Ahmed I Anwar, Lei Lu, Connor J Plaisance, Charles P Daniel, Chelsi J Flanagan, Danielle M Wenger, David McGregor, Giustino Varrassi, Adam M Kaye, Shahab Ahmadzadeh, Elyse M Cornett, Sahar Shekoohi, Alan D Kaye
Fluoroquinolones, a popular antibiotic class that inhibits nucleic acid synthesis of bacteria by disrupting the activity of the enzyme's topoisomerase IV and DNA gyrase, are used to treat bacterial infections. However, the widespread use of these drugs has allowed for the development of microbial resistance in recent years. Quinolones also have many clinically relevant side effects, including psychosis, confusion, seizures, headaches, dizziness, and nausea. Common side effects include tendinitis, myopathy, depression, and fatigue...
February 2024: Curēus