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practical examination neurology

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https://www.readbyqxmd.com/read/28634503/monitoring-the-diagnostic-process-on-an-inpatient-neurology-service
#1
Amar Dhand, Robert Bucelli, Arun Varadhachary, Michael Tsiaklides, Gabriela de Bruin, Gurpreet Dhaliwal
The Institute of Medicine report Improving Diagnosis in Health Care called for tools to monitor physicians' diagnostic process. We addressed this need by developing a tool for clinicians to record and analyze their diagnostic process. The tool was a secure web application in which clinicians used a structured grading system to assess the relative impact of clinical, laboratory, and neuroimaging data for every new diagnosis. Four neurohospitalists used the tool for 6.5 months on a general neurology ward service at a single tertiary-level teaching hospital...
July 2017: Neurohospitalist
https://www.readbyqxmd.com/read/28629741/establishment-of-an-ideal-time-window-model-in-hypothermic-targeted-temperature-management-after-traumatic-brain-injury-in-rats
#2
Wan-Yong Zhao, Shao-Bo Chen, Jing-Jing Wang, Chao Xu, Ming-Liang Zhao, Hua-Jiang Dong, Hai-Qian Liang, Xiao-Hong Li, Yue Tu, Sai Zhang, Chong Chen, Hong-Tao Sun
Although hypothermic-targeted temperature management (HTTM) holds great potential for the treatment of traumatic brain injury (TBI), translation of the efficacy of hypothermia from animal models to TBI patientshas no entire consistency. This study aimed to find an ideal time window model in experimental rats which was more in accordance with clinical practice through the delayed HTTM intervention. Sprague-Dawley rats were subjected to unilateral cortical contusion injury and received therapeutic hypothermia at 15 mins, 2 hours, 4 hours respectively after TBI...
June 16, 2017: Brain Research
https://www.readbyqxmd.com/read/28629403/factors-influencing-professional-life-satisfaction-among-neurologists
#3
Stephanie M Teixeira-Poit, Michael T Halpern, Heather L Kane, Michael Keating, Murrey Olmsted
BACKGROUND: Predicted shortages in the supply of neurologists may limit patients' access to and quality of care for neurological disorders. Retaining neurologists already in practice provides one opportunity to support the overall supply of practicing neurologists. Understanding factors associated with professional life satisfaction (and dissatisfaction) and implementing policies to enhance satisfaction may encourage neurologists to remain in clinical practice. In this paper, we present results from the first study examining factors associated with professional life satisfaction among a large sample of U...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28628591/movement-system-diagnosis
#4
Ann F Van Sant
BACKGROUND AND PURPOSE: This article presents the concept of movement system diagnoses (MSDxs), including an examination of the evolution of the ideas that are shaping the development of MSDxs. SUMMARY OF KEY POINTS: Ideas leading to development of the need for MSDxs are traced, and an overview of Diagnosis Dialog and points of consensus are provided. Four examples from areas of neurologic and pediatric practice where additional work is needed on movement system diagnosis are highlighted...
July 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28617542/assessment-of-behavioral-tasks-performed-by-hemiplegic-patients-with-impaired-dexterity-post-stroke
#5
S Bashir, A Caipa, E B Plow
Disability continues to be one of the leading reasons individuals affected by stroke are left incapable of performing daily activities. Due to the staggering number of disabled adults suffering post-stroke neurological damage, there is a critical need for creating and monitoring effects of successful, intensive stroke therapies. Behavioral assessments are useful tools by which to examine the effectiveness of these stroke therapies as they allow for the investigation of multiple variables, including task performance time, performance quality, and degree of motor function...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28605471/berlin-grading-system-can-stratify-the-onset-and-predict-perioperative-complications-in-adult-moyamoya-disease
#6
Daina Kashiwazaki, Naoki Akioka, Naoya Kuwayama, Kiyohiro Houkin, Marcus Czabanka, Peter Vajkoczy, Satoshi Kuroda
BACKGROUND: The grading system for moyamoya disease is not established. OBJECTIVE: To assess the usefulness of a recently proposed grading system for stratifying the clinical severity and predicting postoperative morbidity in adult moyamoya disease. METHODS: We investigated 176 hemispheres from 89 adult patients who were diagnosed with moyamoya disease in Japan. Their data were analyzed using the Berlin grading system with minor modifications...
June 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28593798/nocebo-in-motor-neuron-disease-systematic-review-and-meta-analysis-of-placebo-controlled-clinical-trials
#7
Faiza Shafiq, Dimos-Dimitrios Mitsikostas, Panagiotis Zis
INTRODUCTION: Nocebo is very prevalent among neurological disorders, resulting in low adherence and treatment outcome. We sought to examine the AEs following placebo administration in placebo-controlled randomised clinical trials (RCTs) for motor neuron disease (MND). METHODS: After a systematic literature search for RCTs for MND pharmacotherapy treatments, we assessed the number of discontinuations because of placebo intolerance. RESULTS: Data were extracted from 12 RCTs fulfilling our search criteria...
June 8, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28586815/speech-motor-sequence-learning-acquisition-and-retention-in-parkinson-disease-and-normal-aging
#8
Jason A Whitfield, Alexander M Goberman
Purpose: The aim of the current investigation was to examine speech motor sequence learning in neurologically healthy younger adults, neurologically healthy older adults, and individuals with Parkinson disease (PD) over a 2-day period. Method: A sequential nonword repetition task was used to examine learning over 2 days. Participants practiced a sequence of 6 monosyllabic nonwords that was retested following nighttime sleep. The speed and accuracy of the nonword sequence were measured, and learning was inferred by examining performance within and between sessions...
May 31, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28577245/from-harmful-treatment-to-secondary-gain-adverse-event-reporting-in-dyspepsia-and-gastroparesis
#9
Klaus Bielefeldt
INTRODUCTION: Medical management of gastroparesis and functional dyspepsia remains difficult with several recent trials showing limited or no benefit. If treatment comes with only marginal improvements, concerns about adverse events become more relevant. We therefore examined the type and outcomes of side effects submitted to a public repository. METHODS: We searched the Federal Adverse Event Reporting System for reports associated with the treatment of dyspepsia or gastroparesis...
June 2, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28576567/developing-a-data-sharing-community-for-spinal-cord-injury-research
#10
REVIEW
Alison Callahan, Kim D Anderson, Michael S Beattie, John L Bixby, Adam R Ferguson, Karim Fouad, Lyn B Jakeman, Jessica L Nielson, Phillip G Popovich, Jan M Schwab, Vance P Lemmon
The rapid growth in data sharing presents new opportunities across the spectrum of biomedical research. Global efforts are underway to develop practical guidance for implementation of data sharing and open data resources. These include the recent recommendation of 'FAIR Data Principles', which assert that if data is to have broad scientific value, then digital representations of that data should be Findable, Accessible, Interoperable and Reusable (FAIR). The spinal cord injury (SCI) research field has a long history of collaborative initiatives that include sharing of preclinical research models and outcome measures...
May 30, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28573372/a-survey-of-anatomical-items-relevant-to-the-practice-of-rheumatology-pelvis-lower-extremity-and-gait
#11
Cristina Hernández-Díaz, José Alvarez-Nemegyei, José Eduardo Navarro-Zarza, Pablo Villaseñor-Ovies, Robert A Kalish, Juan J Canoso, Angélica Vargas, Karla Chiapas-Gasca, Joseph J Biundo, Francisco Javier de Toro Santos, Dennis McGonagle, Simon Carette, Miguel Ángel Saavedra
This study aimed to generate a minimum list of structural and functional anatomical items about the pelvis/hip, knee, ankle/foot, gait, and lower limb innervation, which are most relevant to the practice of rheumatology. To determine their perceived relevance to clinical practice, seven members of the Mexican Clinical Anatomy Task Force compiled an initial list of 470 anatomical items. Ten local and international experts according to a 0-10 Likert scale ranked these items. Of the original list, 101 (21.48%) items were considered relevant (global rate >40)...
June 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28566076/-evaluation-of-viral-etiology-in-central-nervous-system-infections-from-a-university-hospital-point-of-view-in-izmir-based-on-seven-years-data
#12
Ayşın Zeytinoğlu, Selda Erensoy, Rüçhan Sertöz, İmre Altuğlu, Candan Çiçek, Münevver Kayın, Hadiye Şirin, Şafak Taner
The serious diseases of the central nervous system (CNS); encephalitis and meningitis, have high mortality and morbidity rate especially not diagnosed and treated in time. Nucleic acid testing (NAT) is the tool of choice for viral diagnosis in CNS infections. In this study, viral etiological agents found in cerebrospinal fluid (CSF) samples sent to our university hospital virology laboratory for laboratory diagnosis of CNS infections were retrospectively evaluated and results were compared with other reports from our country...
April 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28535498/can-dmco-detect-visual-field-loss-in-neurological-patients-a-secondary-validation-study
#13
Ane Sophie Olsen, Alvilda Thougaard Steensberg, Morten la Cour, Troels Wesenberg Kjaer, Bertil Damato, Lars Hageman Pinborg, Miriam Kolko
Unrecognized visual field loss is caused by a range of blinding eye conditions as well as serious brain diseases. The commonest cause of asymptomatic visual field loss is glaucoma. No screening tools have been proven cost-effective. Damato Multifixation Campimetry Online (DMCO), an inexpensive online test, has been evaluated as a future cost-beneficial tool to detect glaucoma. To further validate DMCO, this study aimed to test DMCO in a preselected population with neurological visual field loss. METHODS: The study design was an evaluation of a diagnostic test...
May 24, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28528730/sir-charles-bell-unheralded-laryngologist
#14
Elliot Abemayor
INTRODUCTION: Sir Charles Bell is renowned and revered as an outstanding surgeon, anatomist, clinician and teacher and his many contributions to various medical fields have been amply described. What are less well-known are his contributions to the field of laryngology. METHODS: Selected clinical and physiological publications by Bell were examined that addressed issues related specifically to the airway or pharynx. These included both case reports and case series...
April 21, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28524254/migraine-nurses-in-primary-care-costs-and-benefits
#15
Jan S P van den Berg, Timothy J Steiner, Petra J L Veenstra, Boudewijn J Kollen
OBJECTIVE: We examined the costs and benefits of introducing migraine nurses into primary care. BACKGROUND: Migraine is one of the most costly neurological diseases. METHODS: We analyzed data from our earlier nonrandomized cohort study comparing an intervention group of 141 patients, whose care was supported by nurses trained in migraine management, and a control group of 94 patients receiving usual care. Estimates of per-person direct costs were based on nurses' salaries and referrals to neurologists...
May 19, 2017: Headache
https://www.readbyqxmd.com/read/28501805/neurological-tests-improve-after-olympic-style-boxing-bouts-a-pretournament-and-post-tournament-study-in-the-2016-women-s-world-boxing-championships
#16
David R Howell, William P Meehan, Michael P Loosemore, Joseph Cummiskey, Jean-Paul Grabner von Rosenberg, David McDonagh
AIM: To prospectively examine the neurocognitive, postural, dual-task and visual abilities of female Olympic-style boxers before and after participation in a tournament. METHODS: Sixty-one females completed the modified Balance Error Scoring System (mBESS), King-Devick test and 3 m timed-up-and-go test in single-task and dual-task conditions. A subset (n=31) completed the CogState computerised neurocognitive test. Initial testing was completed prior to the 2016 Women's World Boxing Championships; each participant repeated the testing protocol within a day of elimination...
May 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28498071/assessment-of-malpractice-claims-due-to-spinal-epidural-abscess
#17
J Mason DePasse, Roy Ruttiman, Adam E M Eltorai, Mark A Palumbo, Alan H Daniels
OBJECTIVE Spinal epidural abscesses (SEAs) can be difficult to diagnose and may result in neurological compromise or even death. Delays in diagnosis or treatment may worsen the prognosis. While SEA presents a high risk for litigation, little is known about the medicolegal ramifications of this condition. An enhanced understanding of potential legal implications is important for practicing spine surgeons, emergency medicine physicians, and internists. METHODS The VerdictSearch database, a large legal-claims database, was queried for "epidural abscess"-related legal cases...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28495807/neurologic-serious-adverse-events-associated-with-nivolumab-plus-ipilimumab-or-nivolumab-alone-in-advanced-melanoma-including-a-case-series-of-encephalitis
#18
James Larkin, Bartosz Chmielowski, Christopher D Lao, F Stephen Hodi, William Sharfman, Jeffrey Weber, Karijn P M Suijkerbuijk, Sergio Azevedo, Hewei Li, Daniel Reshef, Alexandre Avila, David A Reardon
BACKGROUND: Despite unprecedented efficacy across multiple tumor types, immune checkpoint inhibitor therapy is associated with a unique and wide spectrum of immune-related adverse events (irAEs), including neurologic events ranging from mild headache to potentially life-threatening encephalitis. Here, we summarize neurologic irAEs associated with nivolumab and ipilimumab melanoma treatment, present cases of treatment-related encephalitis, and provide practical guidance on diagnosis and management...
June 2017: Oncologist
https://www.readbyqxmd.com/read/28492549/enhanced-neuroprotective-efficacy-of-bone-marrow-mesenchymal-stem-cells-co-overexpressing-bdnf-and-vegf-in-a-rat-model-of-cardiac-arrest-induced-global-cerebral-ischemia
#19
Lili Zhou, Qingming Lin, Peng Wang, Lan Yao, Kahong Leong, Zhiqun Tan, Zitong Huang
Cardiac arrest-induced global cerebral ischemia injury (CA-GCII) usually leads to a poor neurological outcome without an effective treatment. Bone marrow-derived mesenchymal stem cells (BMMSCs) may provide a potential cell-based therapy against neurologic disorders through induction of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF). To optimize the neuroprotective efficacy of BMMSCs further, in this study we have derived BMMSCs, which co-overexpress both BDNF and VEGF, and tested them for the treatment of CA-GCII in a rat model...
May 11, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28471818/spectrum-of-diagnosis-and-disposition-of-patients-referred-to-a-pediatric-orthopaedic-center-for-a-diagnosis-of-intoeing
#20
Shawne Faulks, Kaitlyn Brown, John G Birch
BACKGROUND: Orthopaedic surgeons frequently evaluate otherwise healthy children for concern of intoed gait. Intoeing in otherwise healthy young children due to metatarsus adductus, internal tibial torsion, and increased femoral anteversion do not typically require orthopaedic treatment. This study reviewed the actual diagnosis, management, and disposition of patients referred to a pediatric orthopaedic specialty hospital for a diagnosis of intoeing; the efficacy of an Advanced Practice Provider (APP) assessment program to screen and triage patients with a primary complaint of intoeing; and parental satisfaction with that program...
May 3, 2017: Journal of Pediatric Orthopedics
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