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https://www.readbyqxmd.com/read/29145463/the-chicken-or-the-egg-exploring-bi-directional-associations-between-newcastle-disease-vaccination-and-village-chicken-flock-size-in-rural-tanzania
#1
Julia de Bruyn, Peter C Thomson, Brigitte Bagnol, Wende Maulaga, Elpidius Rukambile, Robyn G Alders
Newcastle disease (ND) is a viral disease of poultry with global importance, responsible for the loss of a potential source of household nutrition and economic livelihood in many low-income food-deficit countries. Periodic outbreaks of this endemic disease result in high mortality amongst free-ranging chicken flocks and may serve as a disincentive for rural households to invest time or resources in poultry-keeping. Sustainable ND control can be achieved through vaccination using a thermotolerant vaccine administered via eyedrop by trained "community vaccinators"...
2017: PloS One
https://www.readbyqxmd.com/read/29135897/is-bmi-a-valid-measure-of-obesity-in-postmenopausal-women
#2
Hailey R Banack, Jean Wactawski-Wende, Kathleen M Hovey, Andrew Stokes
OBJECTIVE: Body mass index (BMI) is a widely used indicator of obesity status in clinical settings and population health research. However, there are concerns about the validity of BMI as a measure of obesity in postmenopausal women. Unlike BMI, which is an indirect measure of obesity and does not distinguish lean from fat mass, dual-energy x-ray absorptiometry (DXA) provides a direct measure of body fat and is considered a gold standard of adiposity measurement. The goal of this study is to examine the validity of using BMI to identify obesity in postmenopausal women relative to total body fat percent measured by DXA scan...
November 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29126231/irrigation-management-and-phosphorus-addition-alter-the-abundance-of-carbon-dioxide-fixing-autotrophs-in-phosphorus-limited-paddy-soil
#3
Xiaohong Wu, Tida Ge, Wende Yan, Juan Zhou, Xiaomeng Wei, Liang Chen, Xiangbi Chen, Paolo Nannipieri, Jinshui Wu
In this study, we assessed the interactive effects of phosphorus (P) application and irrigation methods on the abundances of marker genes (cbbL, cbbM, accA, and aclB) of CO2-fixing autotrophs. We conducted rice-microcosm experiments using a P-limited paddy soil, with and without the addition of P fertiliser (P versus CK), and using two irrigation methods, namely alternate wetting and drying (AWD) and continuous flooding (CF). The abundances of bacterial 16S rRNA, archaeal 16S rRNA, cbbL, cbbM, accA, and aclB genes in the rhizosphere soil (RS) and bulk soil (BS) were quantified...
November 8, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29116125/erratum-large-meta-analysis-of-genome-wide-association-studies-identifies-five-loci-for-lean-body-mass
#4
M Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L Koller, Zoltán Kutalik, Jian'an Luan, Ida Malkin, Janina S Ried, Albert V Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi, Kristina Åkesson, Najaf Amin, Leslie J Baier, Inês Barroso, David A Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B Borecki, Aron S Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A Cauley, Peggy M Cawthon, Henna Cederberg, Zhao Chen, Nam H Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R Cummings, Philip L De Jager, Ilja Demuth, Rosalie A M Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W Enneman, Mike Erdos, Johan G Eriksson, Joel Eriksson, Karol Estrada, Daniel S Evans, Mary F Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L Hanson, Caroline Hayward, Albert Hofman, Eric P Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J Hubal, Alan Hubbard, Kim M Huffman, Lise B Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O Kilpeläinen, Norman Klopp, Jacqueline S L Kloth, Heikki A Koistinen, William E Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L Langdahl, Lenore J Launer, Jong-Young Lee, Markus M Lerch, Joshua R Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Östen Ljunggren, Mattias Lorentzon, Robert N Luben, William Maixner, Fiona E McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Håkan Melhus, Dan Mellström, Simon Melov, Karl Michaëlsson, Braxton D Mitchell, Andrew P Morris, Leif Mosekilde, Anne Newman, Carrie M Nielson, Jeffrey R O'Connell, Ben A Oostra, Eric S Orwoll, Aarno Palotie, Stephen C J Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L Prince, Katri Räikkönen, Stuart H Ralston, Samuli Ripatti, John A Robbins, Jerome I Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stančáková, Elisabeth Steinhagen-Thiessen, Elizabeth A Streeten, Unnur Styrkarsdottir, Karin M A Swart, Sian-Tsung Tan, Mark A Tarnopolsky, Patricia Thompson, Cynthia A Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J Tranah, Jaakko Tuomilehto, Natasja M van Schoor, Arjun Verma, Peter Vollenweider, Henry Völzke, Jean Wactawski-Wende, Mark Walker, Michael N Weedon, Ryan Welch, H-Erich Wichmann, Elisabeth Widen, Frances M K Williams, James F Wilson, Nicole C Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C Chambers, Angela Döring, Cornelia M van Duijn, Michael J Econs, Vilmundur Gudnason, Jaspal S Kooner, Bruce M Psaty, Timothy D Spector, Kari Stefansson, Fernando Rivadeneira, André G Uitterlinden, Nicholas J Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J F Loos, David Karasik, Tamara B Harris, Claes Ohlsson, Douglas P Kiel
A correction to this article has been published and is linked from the HTML version of this article.
November 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/29098763/characterising-infant-and-young-child-feeding-practices-and-the-consumption-of-poultry-products-in-rural-tanzania-a-mixed-methods-approach
#5
Julia De Bruyn, Brigitte Bagnol, Ian Darnton-Hill, Wende Maulaga, Peter C Thomson, Robyn Alders
Suboptimal breastfeeding practices, early initiation of complementary feeding, and monotonous cereal-based diets have been implicated as contributors to continuing high rates of child undernutrition in sub-Saharan Africa. Nutrition-sensitive interventions, including agricultural programs that increase access to nutrient-rich vegetables, legumes, and animal-source foods, have the potential to achieve sustainable improvements in children's diets. In the quest to evaluate the efficacy of such programs in improving growth and development in the first 2 years of life, there is a role for mixed methods research to better understand existing infant and young child feeding practices...
November 2, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29098029/synergistic-anti-proliferative-and-pro-apoptotic-activities-of-5f-and-cisplatin-in-human-non-small-cell-lung-cancer-nci-h23-cells
#6
Yuchan Li, Wende Li, Wusheng Deng, Yuhong Gan, Kefeng Wu, Jie Sun
Two-drug combination chemotherapy, often including cisplatin and one other drug, remains the standard of care for patients with advanced non-small cell lung cancer (NSCLC). To improve the treatment of late-stage NSCLC and decrease the toxicity of combination chemotherapy, the search for novel drugs remains vigorous. Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic acid (5F), a bioactive compound isolated from the herb Pteris semipinnata L., has previously been shown to induce apoptosis and inhibit proliferation in various cancer cells...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29092894/mitochondrial-reactive-oxygen-species-in-lipotoxic-hearts-induces-post-translational-modifications-of-akap121-drp1-and-opa1-that-promote-mitochondrial-fission
#7
Kensuke Tsushima, Heiko Bugger, Adam R Wende, Jamie Soto, Gregory A Jenson, Austin R Tor, Rose McGlauflin, Helena C Kenny, Yuan Zhang, Rhonda Souvenir, Xiao X Hu, Crystal L Black, Renata O Pereira, Vitor A Lira, Kenneth Spitzer, Terry L Sharp, Kooresh I Shoghi, Genevieve C Sparagna, Eva A Rog-Zielinska, Peter Kohl, Oleh Khalimonchuk, Jean E Schaffer, E Dale Abel
Rationale: Cardiac lipotoxicity, characterized by increased uptake, oxidation and accumulation of lipid intermediates, contributes to cardiac dysfunction in obesity and diabetes. However, mechanisms linking lipid overload and mitochondrial dysfunction are incompletely understood. Objective: To elucidate the mechanisms for mitochondrial adaptations to lipid overload in postnatal hearts in vivo. Methods and Results: Using a transgenic mouse model of cardiac lipotoxicity overexpressing long-chain acyl-CoA synthetase 1 in cardiomyocytes, we show that modestly increased myocardial fatty acid uptake leads to mitochondrial structural remodeling with significant reduction in minimum diameter...
November 1, 2017: Circulation Research
https://www.readbyqxmd.com/read/29092231/tunable-dual-wavelength-fiber-laser-with-unique-gain-system-based-on-in-fiber-acousto-optic-mach-zehnder-interferometer
#8
Na Yan, Xiaofang Han, Pengfa Chang, Ligang Huang, Feng Gao, Xuanyi Yu, Wending Zhang, Ze Zhang, Guoquan Zhang, Jingjun Xu
A fast tunable dual-wavelength laser based on in-fiber acousto-optic Mach-Zehnder interferometer (AO-MZI) with new fabrication process is proposed. Not only could the center wavelength of the output laser be optimized with enhanced tuning range about 30 nm by tuning the polarization and the driving frequency of the radio frequency (RF) signal accordingly, but also the spectral spacing between the two output wavelengths could be tuned from ~0 nm to 2.65 nm by controlling the power of the RF signal. The tuning mechanism was also discussed...
October 30, 2017: Optics Express
https://www.readbyqxmd.com/read/29081036/microrna-378-enhances-radiation-response-in-ectopic-and-orthotopic-implantation-models-of-glioblastoma
#9
Wende Li, Yujiao Liu, Weining Yang, Xiaoxing Han, Sen Li, Hao Liu, Leo E Gerweck, Dai Fukumura, Jay S Loeffler, Burton B Yang, Rakesh K Jain, Peigen Huang
Glioblastoma multiforme (GBM) is the most common and highly malignant primary brain tumor, which is virtually incurable due to its therapeutic resistance to radiation and chemotherapy. To develop novel therapeutic approaches for treatment of GBM, we examined the role of miR-378 on tumor growth, angiogenesis, and radiation response in ectopic and orthotopic U87 glioblastoma models. Cell and tumor growth rates, in vitro and in vivo radiation sensitivities, and tumor vascular density were evaluated in U87-GFP and U87-miR-378 tumor lines...
October 28, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29071440/reduction-of-the-relative-centrifugal-force-influences-cell-number-and-growth-factor-release-within-injectable-prf-based-matrices
#10
Simon Wend, Alica Kubesch, Anna Orlowska, Sarah Al-Maawi, Niklas Zender, Andre Dias, Richard J Miron, Robert Sader, Patrick Booms, C James Kirkpatrick, Joseph Choukroun, Shahram Ghanaati
Platelet rich fibrin (PRF) is a blood concentrate system obtained by centrifugation of peripheral blood. First PRF matrices exhibited solid fibrin scaffold, more recently liquid PRF-based matrix was developed by reducing the relative centrifugation force and time. The aim of this study was to systematically evaluate the influence of RCF (relative centrifugal force) on cell types and growth factor release within injectable PRF- in the range of 60-966 g using consistent centrifugation time. Numbers of cells was analyzed using automated cell counting (platelets, leukocytes, neutrophils, lymphocytes and monocytes) and histomorphometrically (CD 61, CD- 45, CD-15+, CD-68+, CD-3+ and CD-20)...
October 25, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29067752/recent-attempted-and-actual-weight-change-in-relation-to-pregnancy-loss-a-prospective-cohort-study
#11
R G Radin, S L Mumford, L A Sjaarda, R M Silver, J Wactawski-Wende, A M Lynch, N J Perkins, L L Lesher, B D Wilcox, S N Hinkle, T C Plowden, K Kim, E F Schisterman
OBJECTIVE: To assess weight change and attempted weight loss during the 12-18 months before spontaneous conception in relation to the risk of pregnancy loss. DESIGN: Prospective cohort study. SETTING: United States, 2007-2011. METHODS: Women (n = 629) who were attempting pregnancy reported at baseline any weight loss attempts over the past 12 months, and their minimum and maximum weights during that time. Follow up lasted one to six menstrual cycles and throughout pregnancy...
October 25, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29041709/hybrid-modes-in-plasmonic-cavity-array-for-enhanced-hot-electron-photodetection
#12
Zhiqiang Yang, Min Liu, Shuhai Liang, Wending Zhang, Ting Mei, Dawei Zhang, Soo Jin Chua
The plasmonic characteristics of a periodic array of cavities in a silicon substrate are investigated for hot-electron photodetection. Resonances of cavity surface plasmons bound to air cavities and silicon cavities, and resonance of Bragg-surface plasmon polaritons are illustrated by the map of metal absorption. Hybrid modes formed with combination of these modes can strongly enhance absorption in metal and be exploited to optimize hot-electron photodetectors for single-band and dual-band detection at optical communication wavelengths...
August 21, 2017: Optics Express
https://www.readbyqxmd.com/read/29037452/balancing-immunity-and-yield-in-crop-plants
#13
REVIEW
Yuese Ning, Wende Liu, Guo-Liang Wang
Crop diseases cause enormous yield losses and threaten global food[ED1] security. The use of highly resistant cultivars can effectively control plant diseases, but in crops, genetic immunity to disease often comes with an unintended reduction in growth and yield. Here, we review recent advances in understanding how nucleotide-binding domain, leucine-rich repeat (NLR) receptors and cell wall-associated kinase (WAK) proteins function in balancing immunity and yield. We also discuss the role of plant hormones and transcription factors in regulating the trade-offs between plant growth and immunity...
October 13, 2017: Trends in Plant Science
https://www.readbyqxmd.com/read/29030573/adjusting-the-catalytic-properties-of-cobalt-ferrite-nanoparticles-by-pulsed-laser-fragmentation-in-water-with-defined-energy-dose
#14
Friedrich Waag, Bilal Gökce, Chakrapani Kalapu, Georg Bendt, Soma Salamon, Joachim Landers, Ulrich Hagemann, Markus Heidelmann, Stephan Schulz, Heiko Wende, Nils Hartmann, Malte Behrens, Stephan Barcikowski
Highly active, structurally disordered CoFe2O4/CoO electrocatalysts are synthesized by pulsed laser fragmentation in liquid (PLFL) of a commercial CoFe2O4 powder dispersed in water. A partial transformation of the CoFe2O4 educt to CoO is observed and proposed to be a thermal decomposition process induced by the picosecond pulsed laser irradiation. The overpotential in the OER in aqueous alkaline media at 10 mA cm(-2) is reduced by 23% compared to the educt down to 0.32 V with a Tafel slope of 71 mV dec(-1)...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29029304/conventional-and-advanced-imaging-of-spine-oncologic-disease-nonoperative-post-treatment-effects-and-unique-spinal-conditions
#15
Falgun H Chokshi, Meng Law, Wende N Gibbs
In this review, we discuss the imaging features of diseases and conditions ranging from neoplastic to nonoperative post-treatment effects to unique conditions of the spine. Additionally, advanced imaging may increase diagnostic certainty in cases where conventional imaging characteristics of benign lesions and malignant pathology are variable.
October 6, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28992799/significant-symptomatic-improvement-of-subacute-cutaneous-lupus-after-testosterone-therapy-in-a-female-to-male-transgender-subject
#16
A Ocon, R Peredo-Wende, J M Kremer, B D Bhatt
No abstract text is available yet for this article.
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28975422/sedentary-time-and-postmenopausal-breast-cancer-incidence
#17
Sarah J O Nomura, Chiranjeev Dash, Vanessa B Sheppard, Deborah Bowen, Matthew Allison, Wendy Barrington, Rowan Chlebowski, Mace Coday, Lifang Hou, Barbara Howard, Michael LaMonte, JoAnn E Manson, Marian L Neuhouser, Electra Paskett, Maryam Sattari, Marcia Stefanick, Jean Wactawski-Wende, Lucile L Adams-Campbell
PURPOSE: The objective of this study was to evaluate the prospective association between sedentary time and postmenopausal breast cancer incidence, and whether associations differ by race/ethnicity, physical activity levels, and body measurements. METHODS: The Women's Health Initiative Observational Study is a prospective cohort among women ages 50-79 years at baseline (1994-1998) (analytic cohort = 70,233). Baseline questionnaire data were used to estimate time spent sitting and total sedentary time...
December 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28944310/metabolic-origins-of-heart-failure
#18
Adam R Wende, Manoja K Brahma, Graham R McGinnis, Martin E Young
For more than half a century, metabolic perturbations have been explored in the failing myocardium, highlighting a reversion to a more fetal-like metabolic profile (characterized by depressed fatty acid oxidation and concomitant increased reliance on glucose utilization). More recently, alterations in ketone body and amino acid/protein metabolism have been described during heart failure, as well as mitochondrial dysfunction and perturbed metabolic signaling (e.g., acetylation, O-GlcNAcylation). Although numerous mechanisms are likely involved, the current review provides recent advances regarding the metabolic origins of heart failure, and their potential contribution toward contractile dysfunction of the heart...
June 2017: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/28913889/prevalence-and-contributors-to-low-grade-inflammation-in-three-u-s-populations-of-reproductive-age-women
#19
Lindsey A Sjaarda, Rose G Radin, Chandra Swanson, Daniel L Kuhr, Sunni L Mumford, Noya Galai, Robert M Silver, Jean Wactawski-Wende, Neil J Perkins, Enrique F Schisterman
BACKGROUND: Inflammation, measured by high-sensitivity C-reactive protein (hsCRP), is linked to adverse reproductive outcomes. However, prevalence and predictors of low-grade inflammation are poorly understood among reproductive age women. Therefore, the current aim was to characterize: (i) the prevalence of elevated hsCRP and (ii) whether the association of various demographic, anthropometric, life style, and metabolic characteristics with higher hsCRP varies across populations of reproductive age women with varying risk profiles for adverse reproductive outcomes...
September 15, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28900765/serum-25-hydroxyvitamin-d-concentrations-and-lung-cancer-risk-in-never-smoking-postmenopausal-women
#20
Ting-Yuan David Cheng, Xiaoling Song, Shirley A A Beresford, Gloria Y F Ho, Karen C Johnson, Mridul Datta, Rowan T Chlebowski, Jean Wactawski-Wende, Lihong Qi, Marian L Neuhouser
PURPOSE: Vitamin D has been implicated in lowering lung cancer risk, but serological data on the association among never-smoking women are limited. We report results examining the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with lung cancer risk among female never smokers. We also examined whether the association was modified by vitamin D supplementation and serum vitamin A concentrations. METHODS: In the Women's Health Initiative, including the calcium/vitamin D (CaD) Trial, we selected 298 incident cases [191 non-small cell lung cancer (NSCLC) including 170 adenocarcinoma] and 298 matched controls of never smokers...
October 2017: Cancer Causes & Control: CCC
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