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https://www.readbyqxmd.com/read/29325349/-introduction-and-interpretation-of-guidelines-on-thromboprophylaxis-in-the-perioperative-period-of-urological-surgery
#1
X Wang, Z Y Liu
Venous thromboembolism had drawn great attention of global experts, as it is the third leading cause of cardiovascular-associated death, ranking after coronary heart disease and stroke. Numerous health care organizations had introduced guidelines for thromboprophylaxis during the perioperative period in their own fields. The paper reviewed the available guidelines pertaining to urological surgery from America Urological Association, American College of Chest Physicians and European Association of Urology. Compared with the first two guidelines, the European Association of Urology guideline is a milestone which recommended the most detailed prophylactic measures for the procedure-specific and patient-specific according to the evidence-based medicine...
January 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29285328/a-new-spiral-dental-implant-a-tool-for-oral-rehabilitation-of-difficult-cases
#2
I Balan, R Calcaterra, D Lauritano, E Grecchi, F Carinci
Spiral dental implant (SDI) is an implant with a conical internal helix that confers the characteristic of self-drilling, self-tapping, and self-bone condensing. These proprieties offer better control during insertion of SDI giving a high primary stabilization, even in poor quality bone. A shorter diameter of SDI results in reduced drilling during insertion and consequently less trauma and minimal bone loss. To address the research purpose, the investigators designed a retrospective cohort study. The study population was composed of 25 patients, 11 males and 14 females that have been treated by Dr...
July 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29235900/treatment-and-discharge-patterns-among-patients-hospitalized-with-non-valvular-atrial-fibrillation-transitioning-from-the-inpatient-to-outpatient-setting
#3
Henry J Henk, Feng Cao, Kenneth Tuell, Kwanza Price, Prianka Singh, Jack Mardekian, Kevin Odell, Chad Patel, Wilson Tan, George H Sands, Shalabh Singhal, Jeffrey Trocio, Lien Vo
OBJECTIVE: To evaluate inpatient oral anticoagulant (OAC) treatment, discharge location, and post-discharge OAC treatment for patients hospitalized with non-valvular atrial fibrillation (NVAF). RESEARCH DESIGN AND METHODS: Retrospective study using claims data linked to hospital electronic health records (EHR). Patients (N = 2,484) were hospitalized with a primary (38%) or secondary (62%) diagnosis of AF without evidence of mitral valvular heart disease or valve replacement between January 2009 and September 2013...
December 13, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29234814/hormone-therapy-for-the-primary-prevention-of-chronic-conditions-in-postmenopausal-women-us-preventive-services-task-force-recommendation-statement
#4
David C Grossman, Susan J Curry, Douglas K Owens, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Menopause occurs at a median age of 51.3 years, and the average US woman who reaches menopause is expected to live another 30 years. The prevalence and incidence of most chronic conditions, such as coronary heart disease, dementia, stroke, fractures, and breast cancer, increase with age; however, the excess risk for these conditions that can be attributed to menopause alone is uncertain. Since the publication of findings from the Women's Health Initiative that hormone therapy use is associated with serious adverse health effects in postmenopausal women, use of menopausal hormone therapy has declined...
December 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29204949/-stroke-prevention-in-atrial-fibrillation-in-germany-situational-analysis-of-treatment-reality-based-on-retrospective-data
#5
Ulrike Mergenthaler, Karel Kostev, Sven Moosmang, Inga-Marion Thate-Waschke, Sylvia Haas
BACKGROUND: Guideline-based, risk-adjusted therapy with anticoagulants reduce thromboembolic stroke risk in patients with atrial fibrillation (AF). METHOD: This study analyzed use of oral anticoagulation in German AF-patients. Access to anonymized patient records was made via IMS Health Disease Analyzer database (sample size: 113,619 patients with ICD-10 Code I48.-; observation period: 11/2010-10/2013). Results were subsequently extrapolated to all general practitioners' (GPs) and cardiological practices in Germany...
December 2017: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/29181456/a-review-of-excessive-sugar-metabolism-on-oral-and-general-health
#6
Kai Foo Chow
Stomatologists and dental practitioners, as they are called in different parts of the world according to tradition and history, are basically physicians who specialise in the study and treatment of diseases of the mouth and surrounding structures. They have always been outstanding in advocating the reduction of sugar consumption, mainly due to its direct connection to the pathogenesis of dental caries. Increasingly, it has come to the attention of researchers, epidemiologists and many healthcare workers and professionals that excessive consumption of sugar is also closely tied to the increase in tandem of our current major health issues like obesity, diabetes, heart, liver and kidney disease, and a host of other associated ailments...
2017: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/29181228/knowledge-of-warning-signs-presenting-symptoms-and-risk-factors-of-coronary-heart-disease-among-the-population-of-dubai-and-northern-emirates-in-uae-a-cross-sectional-study
#7
Nelofar Sami Khan, Syed Ilyas Shehnaz, Gomathi Kadayam Guruswami, Salwa Abdelzaher Mabrouk Ibrahim, Sana Abdul Jabbar Mustafa
Background: To evaluate the level of knowledge regarding warning signs, presenting symptoms and risk factors associated with coronary heart disease (CHD) among population of Dubai and Northern Emirates in UAE. Materials and Methods: A cross sectional survey of 1367 residents of Dubai and Northern Emirates was conducted using a self-administered questionnaire. Results: Respondents were classified into two groups: Young Adult Population (YAP; 18-24 years of age) and General Population (GP; 25 years and older)...
June 2017: Nepal Journal of Epidemiology
https://www.readbyqxmd.com/read/29173598/mechanisms-clinical-significance-and-prevention-of-cognitive-impairment-in-patients-with-atrial-fibrillation
#8
REVIEW
Lena Rivard, Paul Khairy
Atrial fibrillation (AF) and dementia are major health issues, with growing evidence suggesting a consistent association between AF and all forms of dementia. Although dementia and AF share several risk factors, the association appears to be independent of a history of clinical stroke and other comorbidities such as hypertension, heart failure, and diabetes. Proposed mechanisms linking AF to cognitive decline include altered hemodynamics resulting in cerebral hypoperfusion, inflammation, genetic factors, and silent cerebral ischemia due to subclinical microemboli...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29171211/a-prospective-survey-of-atrial-fibrillation-management-for-real-world-guideline-adherence-comparison-study-of-drugs-for-symptom-control-and-complication-prevention-of-atrial-fibrillation-code-af-registry
#9
Hyeongsoo Kim, Tae Hoon Kim, Myung Jin Cha, Jung Myung Lee, Junbeom Park, Jin Kyu Park, Ki Woon Kang, Jaemin Shim, Jae Sun Uhm, Jun Kim, Hyung Wook Park, Eue Keun Choi, Jin Bae Kim, Changsoo Kim, Young Soo Lee, Boyoung Joung
BACKGROUND AND OBJECTIVES: The aging population is rapidly increasing, and atrial fibrillation (AF) is becoming a significant public health burden in Asia, including Korea. This study evaluated current treatment patterns and guideline adherence of AF treatment. METHODS: In a prospective observational registry (COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation [CODE-AF] registry), 6,275 patients with nonvalvular AF were consecutively enrolled between June 2016 and April 2017 from 10 tertiary hospitals in Korea...
October 17, 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/29130542/safety-evaluation-of-p-synephrine-following-15%C3%A2-days-of-oral-administration-to-healthy-subjects-a-clinical-study
#10
Mohd Shara, Sidney J Stohs, Mahmoud M Smadi
Extracts of bitter orange (BOE, Citrus aurantium L.) and its primary protoalkaloid p-synephrine are extensively consumed as dietary supplements. p-Synephrine is also present in foods and juices prepared from various Citrus species. The safety of p-synephrine has been questioned as a result of structural similarities with ephedrine. This study assessed the cardiovascular (stimulant) and hemodynamic effects of BOE (49 mg p-synephrine) daily given to 16 healthy subjects for 15 days in a placebo-controlled, cross-over, double-blinded study...
November 12, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29112241/periodontal-therapy-for-the-management-of-cardiovascular-disease-in-patients-with-chronic-periodontitis
#11
REVIEW
Chunjie Li, Zongkai Lv, Zongdao Shi, Ye Zhu, Yafei Wu, Longjiang Li, Zipporah Iheozor-Ejiofor
BACKGROUND: There is an association between chronic periodontitis and cardiovascular disease (CVD). However, it is not known whether periodontal therapy could prevent or manage CVD in patients with chronic periodontitis. OBJECTIVES: The objective of this systematic review was to investigate the effects of periodontal therapy in preventing the occurrence of, and management or recurrence of, CVD in patients with chronic periodontitis. SEARCH METHODS: Cochrane Oral Health's Information Specialist searched the following databases: Cochrane Oral Health's Trials Register (to 31 August 2017), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, 2017, Issue 7), MEDLINE Ovid (1946 to 31 August 2017), Embase Ovid (1980 to 31 August 2017) and the Cumulative Index to Nursing and Allied Health Literature (CINAHL EBSCO) (1937 to 31 August 2017) ...
November 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29103439/perinatal-health-and-malocclusions-in-preschool-children-findings-from-a-cohort-of-adolescent-mothers-in-southern-brazil
#12
Cássia Cardozo Amaral, Vanessa Polina Pereira da Costa, Marina Sousa Azevedo, Ricardo Tavares Pinheiro, Flávio Fernando Demarco, Marília Leão Goettems
INTRODUCTION: Pregnancy in adolescence has long-term consequences that can negatively influence oral conditions. In this study, we aimed to assess malocclusion in deciduous dentition and its association with prolonged breastfeeding, pacifier use, and perinatal health indicators pertaining to the periods immediately before and after birth. METHODS: This cross-sectional study was nested in a cohort of adolescent mothers who became pregnant from 13 to 19 years of age (mean age, 17...
November 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29096024/antithrombotic-therapy-in-atrial-fibrillation-associated-with-valvular-heart-disease-a-joint-consensus-document-from-the-european-heart-rhythm-association-ehra-and-european-society-of-cardiology-working-group-on-thrombosis-endorsed-by-the-esc-working-group
#13
Gregory Y H Lip, Jean Philippe Collet, Raffaele de Caterina, Laurent Fauchier, Deirdre A Lane, Torben B Larsen, Francisco Marin, Joao Morais, Calambur Narasimhan, Brian Olshansky, Luc Pierard, Tatjana Potpara, Nizal Sarrafzadegan, Karen Sliwa, Gonzalo Varela, Gemma Vilahur, Thomas Weiss, Giuseppe Boriani, Bianca Rocca
Atrial fibrillation (AF) is a major worldwide public health problem, and AF in association with valvular heart disease (VHD) is also common. However, management strategies for this group of patients have been less informed by randomized trials, which have largely focused on 'non-valvular AF' patients. Thrombo-embolic risk also varies according to valve lesion and may also be associated with CHA2DS2VASc score risk factor components, rather than only the valve disease being causal. Given marked heterogeneity in the definition of valvular and non-valvular AF and variable management strategies, including non-vitamin K antagonist oral anticoagulants (NOACs) in patients with VHD other than prosthetic heart valves or haemodynamically significant mitral valve disease, there is a need to provide expert recommendations for professionals participating in the care of patients presenting with AF and associated VHD...
November 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29080863/temporal-trends-in-the-use-and-comparative-effectiveness-of-direct-oral-anticoagulant-agents-versus-warfarin-for-nonvalvular-atrial-fibrillation-a-canadian-population-based-study
#14
Amy Y X Yu, Shaun Malo, Lawrence W Svenson, Stephen B Wilton, Michael D Hill
BACKGROUND: Direct oral anticoagulants (DOACs) are noninferior to warfarin for stroke prevention in atrial fibrillation (AF). We aimed to determine the population risk of stroke and death in incident AF, stratified by anticoagulation status and type, and the temporal trends of oral anticoagulation practice in the post-DOAC approval period. METHODS AND RESULTS: We conducted a population-based cohort study of incident nonvalvular AF cases using administrative health data in Alberta, Canada...
October 28, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29079568/comparative-risk-of-cardiovascular-outcomes-between-topical-and-oral-nonselective-nsaids-in-taiwanese-patients-with-rheumatoid-arthritis
#15
Tzu-Chieh Lin, Daniel H Solomon, Sara K Tedeschi, Kazuki Yoshida, Yea-Huei Kao Yang
BACKGROUND: Topical NSAIDs have less systemic absorption than oral NSAIDs. We examined the risk of cardiovascular events associated with nonselective topical NSAIDs versus oral NSAIDs among patients with rheumatoid arthritis in Taiwan. METHODS AND RESULTS: We conducted a retrospective cohort study that included patients with incident rheumatoid arthritis who were newly starting therapy with nonselective topical NSAIDs or oral NSAIDs. We used the Taiwan National Health Insurance Research Database (NHIRD)...
October 27, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29034445/dental-prevention-and-disease-awareness-in-children-with-congenital-heart-disease
#16
Steffen Koerdt, Julia Hartz, Stefan Hollatz, Gesche Frohwitter, Marco R Kesting, Peter Ewert, Renate Oberhoffer, Herbert Deppe
OBJECTIVES: The importance of excellent oral health is known to be crucial in children with congenital heart diseases (CHD). Data about dental health and disease awareness is limited. This study aims to assess preventive measures taken to improve dental health in children with CHD and to gain insight into disease awareness and knowledge about the importance of oral health in children with CHD and to propose measures that could be taken. MATERIAL AND METHODS: Parents of 150 children with CHD were asked to complete a questionnaire containing specific questions about the preventive measures taken by the parents and dental and medical practitioners and their knowledge about underlying disease and the importance of oral health...
October 16, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29020983/cxcr2-inhibition-a-novel-approach-to-treating-coronary-heart-disease-cicada-study-protocol-for-a-randomised-controlled-trial
#17
Jubin P Joseph, Eliana Reyes, Josephine Guzman, Jim O'Doherty, Hannah McConkey, Satpal Arri, Rahul Kakkar, Nicholas Beckley, Abdel Douiri, Sally F Barrington, Simon R Redwood, Albert Ferro
BACKGROUND: There is emerging evidence of the central role of neutrophils in both atherosclerotic plaque formation and rupture. Patients with lower neutrophil counts following acute coronary syndromes tend to have a greater coronary flow reserve, which is a strong predictor of long-term cardiovascular health. But so far, no data are available regarding the impact of neutrophil inhibition on cardiovascular clinical or surrogate endpoints. Therefore, the aim of this study is to investigate the effects of AZD5069, a cysteine-X-cysteine chemokine receptor 2 (CXCR2) inhibitor, on coronary flow reserve and coronary structure and function in patients with coronary artery disease...
October 11, 2017: Trials
https://www.readbyqxmd.com/read/29017665/folic-acid-effect-on-artemether-induced-cardiac-anomalies-in-mice-embryos
#18
Muhammad Shahid Akhtar, Mohammad Tahir
OBJECTIVE: To determine the role of folic acid in preventing the adverse effects of artemether, on fetal heart in Albino mice. STUDY DESIGN: Experimental study. PLACE AND DURATION OF STUDY: Department of Anatomy, University of Health Sciences, Lahore, from July 2011 to January 2012. METHODOLOGY: Eighteen pregnant Albino mice were randomly divided into three groups A, B, and C of six mice each. The control group Awas treated with intramuscular injection of solvent arachis oil 10...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28991002/estimating-the-effect-of-preventable-treatment-discontinuation-on-health-outcomes
#19
M A Brookhart, D Reams, P J Dluzniewski, A Kshirsagar, L Walsh, B D Bradbury
BACKGROUND: There is increased interest in studying the effects of medication adherence on health outcomes. However, if patients appropriately stop treatment because of side effects and treatment failure, it is neither possible nor clinically meaningful to estimate the effect of full medication adherence. METHODS: We present an analysis designed to estimate the effect of non-medical (preventable) discontinuation of cinacalcet, an oral medication approved to treat secondary hyperparathyroidism in patients with end stage renal disease on dialysis on mortality and heart failure...
October 4, 2017: Epidemiology
https://www.readbyqxmd.com/read/28953214/clinical-trials-in-menopause
#20
Kathryn I Marko, James A Simon
OBJECTIVE: Clinical trials in menopause have undergone much scrutiny over the years. This has led to significant shifts in the treatment of symptomatic menopause and a substantial impact on women. We aim to delineate the key studies contributing to this controversy and highlight new directions specifically related to menopausal hormone therapy (HT) and vascular disease risk. METHODS: We performed a search of sentinel studies delineating the risks and benefits of HT in otherwise healthy postmenopausal women...
September 25, 2017: Menopause: the Journal of the North American Menopause Society
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