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https://www.readbyqxmd.com/read/28806681/human-biomonitoring-of-polycyclic-aromatic-hydrocarbonsand-metals-in-the-general-population-residing-near-the-municipal-solid-waste-incinerator-of-modena-italy
#1
Maria Giulia Gatti, Petra Bechtold, Laura Campo, Giovanna Barbieri, Giulia Quattrini, Andrea Ranzi, Sabrina Sucato, Luca Olgiati, Elisa Polledri, Michael Romolo, Laura Iacuzio, Giuliano Carrozzi, Paolo Lauriola, Carlo A Goldoni, Silvia Fustinoni
BACKGROUND AND OBJECTIVES: A cross-sectional biomonitoring study was carried out to investigate exposure to incinerator emission in relation to the body burden of selected biomarkers in the population living around the plant. METHODS: Approximately 500 people, aged 18-69 yrs, living within 4 km from the incinerator were randomly selected form the population register. Exposure was measured through fall-out maps of particulate matter (PM), used as tracer for incinerator emissions...
August 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/28806507/triboelectric-nanogenerator-enabled-body-sensor-network-for-self-powered-human-heart-rate-monitoring
#2
Zhiming Lin, Jun Chen, Xiaoshi Li, Zhihao Zhou, Keyu Meng, Wei Wei, Jin Yang, Zhong Lin Wang
Heart rate monitoring plays a critical role in personal healthcare management. A low-cost, non-invasive and user-friendly heart rate monitoring system is highly desirable. Here, a self-powered wireless Body Sensor Network (BSN) system is developed for heart rate monitoring via integration of a downy-structure based triboelectric nanogenerator (D-TENG), a power management circuit, a heart rate sensor, a signal processing unit and Bluetooth module for wireless data transmission. By converting the inertia energy of human walking into electric power, a maximum power of 2...
August 14, 2017: ACS Nano
https://www.readbyqxmd.com/read/28806064/conditional-displacement-hybridization-assay-for-multiple-snp-phasing
#3
Tsz Wing Fan, Henson L Lee Yu, I-Ming Hsing
The two chromosomal copies of the human genome are highly polymorphic, and the allelic content on each strand can dictate a person's biological outcomes. While many of the current diagnostic tools are able to detect the presence of multiple mutations at the same time, most cannot determine the phase of these mutations unless long-range PCR or sequencing techniques are used or if templates are compartmentalized into single copies prior to amplification. Here, an enzyme-coupled hybridization assay, named Conditional Displacement Hybridization Assay (CDHA), is described for the concurrent and rapid determination of the presence and phase of SNP variants...
August 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28805419/creating-space-for-relationships
#4
Susan L Maataoui, Jodi S Hardwick, Tessa S Lundquist
Sexuality is a key component of personality and behavior, encompassing basic human needs for touch, intimacy, love, affection, and sexual behavior. The design of long-term care facilities makes it almost impossible for a resident to be sexually intimate, to share romantic moments, or to have a meal in a private setting. This case study describes the rationale and process used to establish a private guestroom called the Family Room at Patriots Place, the specialized dementia unit in the Veterans Affairs (VA) Maine Healthcare System Community Living Center (CLC)...
August 2017: Psychological Services
https://www.readbyqxmd.com/read/28802637/blood-pressure-responses-to-dietary-sodium-association-with-autonomic-cardiovascular-function-in-normotensive-adults
#5
Evan L Matthews, Michael S Brian, David G Edwards, Sean D Stocker, Megan M Wenner, William B Farquhar
Blood pressure responses to dietary sodium vary widely person-to-person. Salt sensitive rodent models display altered autonomic function, a trait thought to contribute to poor cardiovascular health. Thus, we hypothesized that increased salt sensitivity (SS) in normotensive humans would be associated with increased muscle sympathetic nerve activity (MSNA), decreased high frequency heart rate variability (HF-HRV), and decreased baroreflex sensitivity. Healthy normotensive men and women completed 1week of high (300mmol·day(-1)) and 1week of low (20mmol·day(-1)) dietary sodium (random order) with 24h mean arterial pressure (MAP) assessed on the last day of each diet to assess SS...
August 6, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28801406/speak-up-culture-in-an-intensive-care-unit-in-hong-kong-a-cross-sectional-survey-exploring-the-communication-openness-perceptions-of-chinese-doctors-and-nurses
#6
George Wing Yiu Ng, Jack Kwok Hung Pun, Eric Hang Kwong So, Wendy Wai Hang Chiu, Avis Siu Ha Leung, Yuk Han Stone, Chung Ling Lam, Sarah Pui Wa Lai, Rowlina Pui Wah Leung, Hing Wah Luk, Anne Kit Hung Leung, Kin Wah Au Yeung, Kang Yiu Lai, Diana Slade, Engle Angela Chan
OBJECTIVES: Despite growing recognition of the importance of speaking up to protect patient safety in critical care, little research has been performed in this area in an intensive care unit (ICU) context. This study explored the communication openness perceptions of Chinese doctors and nurses and identified their perceptions of issues in ICU communication, their reasons for speaking up and the possible factors and strategies involved in promoting the practice of speaking up. DESIGN: A mixed-methods design with quantitative and sequential qualitative components was used...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801255/decoding-naturalistic-experiences-from-human-brain-activity-via-distributed-representations-of-words
#7
REVIEW
Satoshi Nishida, Shinji Nishimoto
Natural visual scenes induce rich perceptual experiences that are highly diverse from scene to scene and from person to person. Here, we propose a new framework for decoding such experiences using a distributed representation of words. We used functional magnetic resonance imaging (fMRI) to measure brain activity evoked by natural movie scenes. Then, we constructed a high-dimensional feature space of perceptual experiences using skip-gram, a state-of-the-art distributed word embedding model. We built a decoder that associates brain activity with perceptual experiences via the distributed word representation...
August 8, 2017: NeuroImage
https://www.readbyqxmd.com/read/28801245/episodic-future-thinking-and-future-based-decision-making-in-a-case-of-retrograde-amnesia
#8
Flavia De Luca, Francesca Benuzzi, Elena Bertossi, Davide Braghittoni, Giuseppe di Pellegrino, Elisa Ciaramelli
We investigated episodic future thinking (EFT) and future-based cognition and decision-making in patient SG, who developed a dense retrograde amnesia following hypoxia due to a cardiac arrest. Despite intact general cognitive and executive functioning, SG was unable to remember events from his entire lifetime. He had, however, relatively spared anterograde memory and general semantic knowledge. Voxel-based morphometry detected a reduction of gray matter in the thalamus, cerebellum and fusiform gyrus bilaterally, and, at a reduced threshold, in several regions of the autobiographical memory network, including the hippocampi...
August 9, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28800997/palliative-care-and-human-rights-a-decade-of-evolution-in-standards
#9
Tamar Ezer, Diederik Lohman, Gabriela B de Luca
CONTEXT: Human rights standards to address palliative care have developed over the last decade. OBJECTIVES: This paper aims to examine key milestones in the evolution of human rights standards to address palliative care, relevant advocacy efforts, and areas for further growth. METHODS: The paper provides an analysis of human rights standards in the context of palliative care through the lens of the right to health, freedom from torture and ill treatment, and the rights of older persons and children...
August 8, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28800810/international-emergency-psychiatry-challenges-disaster-medicine-war-human-trafficking-displaced-persons
#10
REVIEW
Michael Jaung, Suni Jani, Sophia Banu, Joy M Mackey
Mental health disorders are a major cause of morbidity and a growing burden in low-income and middle-income countries; but there is little existing literature on the detailed epidemiology, diagnosis, and treatment in low-resource settings. Special situations with vulnerable populations, such as those created by international humanitarian emergencies, refugees or internally displaced people, and victims of human trafficking, are increasing in prevalence. These victims are often resettled in developed countries and come to the emergency department seeking care...
September 2017: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28800511/the-serotonin-transporter-promoter-variant-5-httlpr-and-childhood-adversity-are-associated-with-the-personality-trait-openness-to-experience
#11
Md Shafiqur Rahman, Peter Guban, Mei Wang, Philippe A Melas, Yvonne Forsell, Catharina Lavebratt
There is evidence supporting an association between the serotonin-transporter-linked polymorphic region (5-HTTLPR) and the Five Factor Model (FFM) of human personality. 5-HTTLPR has also been found to interact with stressful life events to increase risk of psychopathology. In the present study, by taking into account stressful life events in the form of childhood adversity, we examined the association between 5-HTTLPR and FFM traits using an adult Swedish cohort (N = 3112). We found that 5-HTTLPR was significantly associated with openness (to experience)...
July 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28800349/musculoskeletal-disorders-personality-traits-psychological-distress-and-accident-proneness-of-chinese-coal-miners
#12
Mingming Deng, Feng Wu, Jun Wang, Linyan Sun
BACKGROUND: Human factors comprise one of the important reasons leading to the casualty accidents in coal mines. OBJECTIVE: The aim of this study was to analyze the relationships among musculoskeletal disorders (MSDs), personality traits, psychological distress, and accident proneness of coal miners. PARTICIPANTS: There were 1500 Chinese coal miners surveyed in this study. Among these miners, 992 valid samples were obtained. METHODS: The study surveyed the MSDs, personality traits, psychological distress, and accident proneness of coal miners with MSDs Likert scale, Eysenck personality questionnaire, Symptom Checklist-90 (SCL-90) scale, and accident proneness questionnaire, respectively...
2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28799801/cross-generational-effects-of-alcohol-dependence-in-humans-on-hras-and-tp53-methylation-in-offspring
#13
Shirley Y Hill, Gregory Rompala, Gregg E Homanics, Nicholas Zezza
AIM: We hypothesized that cross-generational effects of alcohol exposure could alter DNA methylation and expression of the HRAS oncogene and TP53 tumor suppressor gene that drive cancer development. METHODS: DNA methylation of the HRAS and TP53 genes was tested in samples from young participants (Mean age of 13.4 years). RESULTS: Controlling for both personal use and maternal use of substances during pregnancy, familial alcohol dependence was associated with hypomethylation of CpG sites in the HRAS promoter region and hypermethylation of the TP53 gene...
August 11, 2017: Epigenomics
https://www.readbyqxmd.com/read/28799199/refining-moral-agency-insights-from-moral-psychology-and-moral-philosophy
#14
Aimee Milliken
Research in moral psychology has recently raised questions about the impact of context and the environment on the way the human mind works. In a 2012 call to action, Paley wrote: "If some of the conclusions arrived at by moral psychologists are true, they are directly relevant to the way nurses think about moral problems, and present serious challenges to favoured concepts in nursing ethics, such as the ethics of care, virtue, and the unity of the person" (p. 80). He urges nurse ethicists and scholars to evaluate the impact these findings may have for moral theory...
August 11, 2017: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/28799165/meanings-of-troubled-conscience-and-how-to-deal-with-it-expressions-of-persian-speaking-enrolled-nurses-in-sweden
#15
Monir Mazaheri, Eva Ericson-Lidman, Öhlén Joakim, Astrid Norberg
INTRODUCTION: A feature of the healthcare system in Sweden, particularly in the care of older people, is its cultural diversity in terms of having considerable numbers of both caregivers and care recipients with an immigrant background. Considering the influence of culture in ethical decision-making processes, the idea of conscience and the adverse effects of a troubled conscience, it is important to study the concepts of conscience and troubled conscience in culturally diverse populations...
August 10, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28798318/sunscreen-products-impair-the-early-developmental-stages-of-the-sea-urchin-paracentrotus-lividus
#16
Cinzia Corinaldesi, Elisabetta Damiani, Francesca Marcellini, Carla Falugi, Luca Tiano, Francesca Brugè, Roberto Danovaro
Marine ecosystems are increasingly threatened by the release of personal care products. Among them, sunscreens are causing concern either for the effects on skin protection from UV radiation and for the potential impacts on marine life. Here, we assessed the UVA protective efficacy of three sunscreens on human dermal fibroblasts, including two common products in Europe and USA, and an eco-friendly product. The sunscreens' effects were also tested on Paracentrotus lividus, a marine species possibly threatened by these contaminants...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28798200/wearable-physiological-monitoring-for-human-thermal-work-strain-optimization
#17
Mark J Buller, Alexander Pearson Welles, Karl E Friedl
Safe performance limits of soldiers and athletes have typically relied on predictive work-rest models of ambient conditions, average work intensity, and characteristics of the population. Bioengineering advances in noninvasive sensor technologies including miniaturization, reduced cost, power requirements, and comfort now make it possible to produce individual predictions of safe thermal-work limits. These precision medicine assessments depend on the development of thoughtful algorithms based on physics and physiology...
August 10, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28797269/a-reduction-in-malaria-transmission-intensity-in-northern-ghana-after-7%C3%A2-years-of-indoor-residual-spraying
#18
Sylvester Coleman, Samuel K Dadzie, Aklilu Seyoum, Yemane Yihdego, Peter Mumba, Dereje Dengela, Philip Ricks, Kristen George, Christen Fornadel, Daniel Szumlas, Paul Psychas, Jacob Williams, Maxwell A Appawu, Daniel A Boakye
BACKGROUND: Indoor residual spraying (IRS) is being implemented as one of the malaria prevention methods in the Northern Region of Ghana. Changes in longevity, sporozoite and entomological inoculation rates (EIRs) of major malaria vectors were monitored to assess the impact of IRS in selected districts. METHODS: Monthly human landing catches (HLCs) were used to collect mosquitoes from sentinel sites in three adjacent districts between July 2009 and December 2014: Savelugu Nanton (SND) where IRS had been implemented from 2008 to 2014; Tolon Kumbungu (TKD) where IRS had been implemented between 2008 and 2012 and Tamale Metropolis (TML) with no history of IRS...
August 10, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28797109/upper-limb-movements-can-be-decoded-from-the-time-domain-of-low-frequency-eeg
#19
Patrick Ofner, Andreas Schwarz, Joana Pereira, Gernot R Müller-Putz
How neural correlates of movements are represented in the human brain is of ongoing interest and has been researched with invasive and non-invasive methods. In this study, we analyzed the encoding of single upper limb movements in the time-domain of low-frequency electroencephalography (EEG) signals. Fifteen healthy subjects executed and imagined six different sustained upper limb movements. We classified these six movements and a rest class and obtained significant average classification accuracies of 55% (movement vs movement) and 87% (movement vs rest) for executed movements, and 27% and 73%, respectively, for imagined movements...
2017: PloS One
https://www.readbyqxmd.com/read/28796840/yes-research-matters
#20
Mari L Shinohara
My father was diagnosed with stomach cancer recently. Luckily, it was still at an early stage, and endoscopic surgery successfully took care of it. My father was fortunate; since people with stomach cancer do not show clear symptoms in the early stages, the disease is often not diagnosed until it becomes advanced. In his case, the diagnosis started from a suggestion by his doctor to check whether he had a gastric infection with Helicobacter pylori, a bacterial species found in the digestive tract. In Japan, where he lives, a majority of gastric cancer patients (more than 99%) have been infected with H...
August 2017: PLoS Pathogens
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