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Jim van os

Ada Wai Tung Fung, Wai-Chi Chan, Corine Sau-Man Wong, Eric Yu-Hai Chen, Roger Man-Kin Ng, Edwin Ho-Ming Lee, Wing-Chung Chang, Se-Fong Hung, Eric Fuk-Chi Cheung, Pak-Chung Sham, Helen Fung-Kum Chiu, Ming Lam, Tin-Po Chiang, Jim van Os, Joseph Tak-Fai Lau, Glyn Lewis, Paul Bebbington, Linda Chiu Wa Lam
BACKGROUND: Anxiety disorders are prevalent yet under-recognized in late life. We examined the prevalence of anxiety disorders in a representative sample of community dwelling older adults in Hong Kong. METHOD: Data on 1,158 non-demented respondents aged 60-75 years were extracted from the Hong Kong Mental Morbidity survey (HKMMS). Anxiety was assessed with the revised Clinical Interview Schedule (CIS-R). RESULT: One hundred and thirty-seven respondents (11...
October 21, 2016: International Psychogeriatrics
Lotte Berk, Martin van Boxtel, Sebastian Köhler, Jim van Os
OBJECTIVE: In cross-sectional studies, positive affect (PA) has been associated with higher levels of cognitive functioning. This study examined whether positive affect (PA) is associated with change in cognitive function over 12 years in an adult population sample. METHODS: Participants (n = 258), aged 40 to 82 years, were drawn from a subsample of the Maastricht Aging Study (MAAS) and assessed at baseline, 6 years and 12 years. PA was measured at baseline with a Dutch translation of the Positive and Negative Affect Schedule (PANAS)...
October 17, 2016: International Journal of Geriatric Psychiatry
Sanne C T Peeters, Ed H B M Gronenschild, Therese van Amelsvoort, Jim van Os, Machteld Marcelis, Rene Kahn, Durk Wiersma, Richard Bruggeman, Wiepke Cahn, Lieuwe de Haan, Carin Meijer, Inez Myin-Germeys
BACKGROUND: Previous research has shown that the human brain can be represented as a complex functional network that is characterized by specific topological properties, such as clustering coefficient, characteristic path length, and global/local efficiency. Patients with psychotic disorder may have alterations in these properties with respect to controls, indicating altered efficiency of network organization. This study examined graph theoretical changes in relation to differential genetic risk for the disorder and aimed to identify clinical correlates...
September 2016: Brain and Behavior
Rosan Luijcks, Catherine J Vossen, Suzanne Roggeveen, Jim van Os, Hermie J Hermens, Richel Lousberg
Human and animal research indicates that exposure to early life adversity increases stress sensitivity later in life. While behavioral markers of adversity-induced stress sensitivity have been suggested, physiological markers remain to be elucidated. It is known that trapezius muscle activity increases during stressful situations. The present study examined to what degree early life adverse events experienced during early childhood (0-11 years) and adolescence (12-17 years) moderate experimentally induced electromyographic (EMG) stress activity of the trapezius muscles, in an experimental setting...
September 2016: Medicine (Baltimore)
Maarten Bak, Marjan Drukker, Laila Hasmi, Jim van Os
INTRODUCTION: Dynamic relationships between the symptoms of psychosis can be shown in individual networks of psychopathology. In a single patient, data collected with the Experience Sampling Method (ESM-a method to construct intensive time series of experience and context) can be used to study lagged associations between symptoms in relation to illness severity and pharmacological treatment. METHOD: The patient completed, over the course of 1 year, for 4 days per week, 10 daily assessments scheduled randomly between 10 minutes and 3 hours apart...
2016: PloS One
Tim Batink, Jindra Bakker, Thomas Vaessen, Zuzana Kasanova, Dina Collip, Jim van Os, Marieke Wichers, Inez Germeys, Frenk Peeters
BACKGROUND: With the development of mHealth, it is possible to treat patients in their natural environment. Mobile technology helps to bridge the gap between the therapist's office and the "real world." The ACT in Daily Life training (ACT-DL) was designed as an add-on intervention to help patients practice with acceptance and commitment therapy in their daily lives. The ACT-DL consists of two main components: daily monitoring using experience sampling and ACT training in daily life. OBJECTIVES: To assess the acceptability and feasibility of the ACT-DL in a general outpatient population...
2016: JMIR MHealth and UHealth
Marta de Castro-Catala, Martine van Nierop, Neus Barrantes-Vidal, Paula Cristóbal-Narváez, Tamara Sheinbaum, Thomas R Kwapil, Elionora Peña, Nele Jacobs, Catherine Derom, Evert Thiery, Jim van Os, Ruud van Winkel, Araceli Rosa
Childhood trauma exposure is a robust environmental risk factor for psychosis. However, not all exposed individuals develop psychotic symptoms later in life. The Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) has been suggested to moderate the psychosis-inducing effects of childhood trauma in clinical and nonclinical samples. Our study aimed to explore the interaction effect between childhood trauma and the BDNF Val66Met polymorphism on subclinical psychotic experiences (PEs). This was explored in two nonclinical independent samples: an undergraduate and technical-training school student sample (n = 808, sample 1) and a female twin sample (n = 621, sample 2)...
August 24, 2016: Journal of Psychiatric Research
Steven Honings, Marjan Drukker, Martine van Nierop, Ruud van Winkel, Hans-Ulrich Wittchen, Roselind Lieb, Margreet Ten Have, Ron de Graaf, Saskia van Dorsselaer, Jim van Os
This study examines the longitudinal associations between psychotic experiences (PE) and incident suicidal ideation and behaviour in the general population, and to what degree the association may be confounded by non-psychotic psychopathology. Data from three prospective, general population cohorts were combined into one dataset (n=15,837) and analysed using logistic regression, controlling for continuous measures of depression, anxiety and mania symptoms. Analyses were conducted in the entire sample, and in subsamples stratified by presence or absence of mental disorders...
November 30, 2016: Psychiatry Research
Ana Catalan, Maider Gonzalez de Artaza, Sonia Bustamante, Pablo Orgaz, Luis Osa, Virxinia Angosto, Cristina Valverde, Amaia Bilbao, Arantza Madrazo, Jim van Os, Miguel Angel Gonzalez-Torres
BACKGROUND: Facial emotion recognition (FER) is essential to guide social functioning and behaviour for interpersonal communication. FER may be altered in severe mental illness such as in psychosis and in borderline personality disorder patients. However, it is unclear if these FER alterations are specifically related to psychosis. Awareness of FER alterations may be useful in clinical settings to improve treatment strategies. The aim of our study was to examine FER in patients with severe mental disorder and their relation with psychotic symptomatology...
2016: PloS One
Steven Honings, Marjan Drukker, Margreet Ten Have, Ron de Graaf, Saskia van Dorsselaer, Jim van Os
BACKGROUND: In cross-sectional, general population studies, psychotic experiences have been associated with an increased risk of physical violence perpetration and arrest. However, longitudinal research on this topic is lacking. Moreover, it remains unclear whether subjects with psychotic experiences are also at risk of displaying psychological violence. The present study aims to investigate these associations. METHOD: The longitudinal association between baseline psychotic experiences and six-year incidence of violence perpetration and three-year incidence of arrest was studied in a prospective cohort of 6646 general population adults...
2016: PloS One
Sinan Guloksuz, Martine van Nierop, Maarten Bak, Ron de Graaf, Margreet Ten Have, Saskia van Dorsselaer, Nicole Gunther, Roselind Lieb, Ruud van Winkel, Hans-Ulrich Wittchen, Jim van Os
BACKGROUND: We investigated to what degree environmental exposure (childhood trauma, urbanicity, cannabis use, and discrimination) impacts symptom connectivity using both continuous and categorical measures of psychopathology. METHODS: Outcomes were continuous symptom dimensions of self-reported psychopathology using the Self-report Symptom Checklist-90-R in 3021 participants from The Early Developmental Stages of the Psychopathology (EDSP) study and binary DSM-III-R categories of mental disorders and a binary measure of psychotic symptoms in 7076 participants from The Netherlands Mental Health Survey and Incidence Study (NEMESIS-1)...
2016: BMC Psychiatry
Johanna T W Wigman, Stijn de Vos, Marieke Wichers, Jim van Os, Agna A Bartels-Velthuis
Our ability to accurately predict development and outcome of early expression of psychosis is limited. To elucidate the mechanisms underlying psychopathology, a broader, transdiagnostic approach that acknowledges the complexity of mental illness is required. The upcoming network paradigm may be fruitful here. In this study, we applied a transdiagnostic network approach to psychosis. Data pertain to the third wave (second follow-up) of a sample of adolescents originally recruited at age 7-8 years. At baseline, N = 347 children with auditory verbal hallucinations (AVH) and N = 347 control children were included...
July 6, 2016: Schizophrenia Bulletin
Holger Garn, Sabine Bahn, Bernhard T Baune, Elisabeth B Binder, Hans Bisgaard, Talal A Chatila, Triantafyllos Chavakis, Carsten Culmsee, Udo Dannlowski, Steffen Gay, James Gern, Tari Haahtela, Tilo Kircher, Ulf Müller-Ladner, Markus F Neurath, Klaus T Preissner, Christoph Reinhardt, Graham Rook, Shannon Russell, Bernd Schmeck, Thaddeus Stappenbeck, Ulrich Steinhoff, Jim van Os, Scott Weiss, Michael Zemlin, Harald Renz
Recent research indicates that chronic inflammatory diseases, including allergies and autoimmune and neuropsychiatric diseases, share common pathways of cellular and molecular dysregulation. It was the aim of the International von-Behring-Röntgen Symposium (October 16-18, 2014, in Marburg, Germany) to discuss recent developments in this field. These include a concept of biodiversity; the contribution of urbanization, lifestyle factors, and nutrition (eg, vitamin D); and new mechanisms of metabolic and immune dysregulation, such as extracellular and intracellular RNAs and cellular and mitochondrial stress...
July 2016: Journal of Allergy and Clinical Immunology
Jim van Os, Uli Reininghaus
A large body of research indicates that weak expressions of positive psychotic symptoms ("psychotic experiences") can be measured in the general population, and likely represent the behavioural manifestation of distributed multifactorial (genetic and non-genetic) risk for psychosis. Psychotic experiences are a transdiagnostic phenomenon: the majority of individuals with these experiences have a diagnosis of non-psychotic disorder, particularly common mental disorder, in which psychotic experiences predict greater illness severity and poorer treatment response...
June 2016: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Patrick Domen, Sanne Peeters, Stijn Michielse, Ed Gronenschild, Wolfgang Viechtbauer, Alard Roebroeck, Jim van Os, Machteld Marcelis
BACKGROUND: Although widespread reduced white matter (WM) integrity is a consistent finding in cross-sectional diffusion tensor imaging (DTI) studies of schizophrenia, little is known about the course of these alterations. This study examined to what degree microstructural WM alterations display differential trajectories over time as a function of level of psychosis liability. METHODS: Two DTI scans with a 3-year time interval were acquired from 159 participants (55 patients with a psychotic disorder, 55 nonpsychotic siblings and 49 healthy controls) and processed with tract-based spatial statistics...
May 17, 2016: Schizophrenia Bulletin
Adela-Maria Isvoranu, Denny Borsboom, Jim van Os, Sinan Guloksuz
The spectrum of psychotic disorder represents a multifactorial and heterogeneous condition and is thought to result from a complex interplay between genetic and environmental factors. In the current paper, we analyze this interplay using network analysis, which has been recently proposed as a novel psychometric framework for the study of mental disorders. Using general population data, we construct network models for the relation between 3 environmental risk factors (cannabis use, developmental trauma, and urban environment), dimensional measures of psychopathology (anxiety, depression, interpersonal sensitivity, obsessive-compulsive disorder, phobic anxiety, somatizations, and hostility), and a composite measure of psychosis expression...
July 2016: Schizophrenia Bulletin
Svetlana A Ivanova, Anton Jm Loonen, P Roberto Bakker, Maxim B Freidin, Nienke J Ter Woerds, Asmar Fy Al Hadithy, Arkadiy V Semke, Olga Yu Fedorenko, Jacobus Rbj Brouwers, Nikolay A Bokhan, Jim van Os, Peter N van Harten, Bob Wilffert
OBJECTIVES: An established theory for the pathogenesis of tardive dyskinesia is disturbed dopaminergic receptor sensitivity and/or dopaminergic intracellular signaling. We examined associations between genetic variants of neurotransmitter receptors and tardive dyskinesia. METHODS: We assessed tardive dyskinesia in Caucasian psychiatric inpatients from Siberia (N = 431) and a long-stay population from the Netherlands (N = 168). These patients were genotyped for 43 tag single nucleotide polymorphisms in five neurotransmitter receptor genes, and the results for the two populations were compared...
2016: SAGE Open Medicine
Jim van Os
No abstract text is available yet for this article.
June 1, 2016: JAMA Psychiatry
Wim Veling, Roos Pot-Kolder, Jacqueline Counotte, Jim van Os, Mark van der Gaag
The impact of social environments on mental states is difficult to assess, limiting the understanding of which aspects of the social environment contribute to the onset of psychotic symptoms and how individual characteristics moderate this outcome. This study aimed to test sensitivity to environmental social stress as a mechanism of psychosis using Virtual Reality (VR) experiments. Fifty-five patients with recent onset psychotic disorder, 20 patients at ultra high risk for psychosis, 42 siblings of patients with psychosis, and 53 controls walked 5 times in a virtual bar with different levels of environmental social stress...
April 2, 2016: Schizophrenia Bulletin
Lars Clemmensen, Agna A Bartels-Velthuis, Rókur Av F Jespersen, Jim van Os, Els M A Blijd-Hoogewys, Lise Ankerstrøm, Mette Væver, Peter F Daniel, Marjan Drukker, Pia Jeppesen, Jens R M Jepsen
BACKGROUND: Theory-of-Mind (ToM) keeps on developing in late childhood and early adolescence, and the study of ToM development later in childhood had to await the development of sufficiently sensitive tests challenging more mature children. The current study aimed to investigate the psychometric properties of the Danish version of the Theory-of-Mind Storybook Frederik (ToM-Frederik). METHODS: We assessed whether ToM-Frederik scores differed between a group of 41 typically developing (TD) children and a group of 33 children with High Functioning Autism Spectrum Disorder (HFASD)...
2016: Frontiers in Psychology
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