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Jim van os

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https://www.readbyqxmd.com/read/29036532/behavioral-pattern-separation-and-its-link-to-the-neural-mechanisms-of-fear-generalization
#1
Iris Lange, Liesbet Goossens, Stijn Michielse, Jindra Bakker, Shmuel Lissek, Silvia Papalini, Simone Verhagen, Nicole Leibold, Machteld Marcelis, Marieke Wichers, Ritsaert Lieverse, Jim van Os, Therese van Amelsvoort, Koen Schruers
Fear generalization is a prominent feature of anxiety disorders and post-traumatic stress disorder. It is defined as enhanced fear responding to a stimulus that bears similarities, but is not identical to a threatening stimulus. Pattern separation, a hippocampal-dependent process, is critical for stimulus discrimination; it transforms similar experiences or events into non-overlapping representations. The current study is the first in humans to investigate the extent to which fear generalization relies on behavioral pattern separation abilities...
September 26, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29023568/demonstrating-the-reliability-of-transdiagnostic-mhealth-routine-outcome-monitoring-in-mental-health-services-using-experience-sampling-technology
#2
Simone J W Verhagen, Juliënne A Berben, Carsten Leue, Anne Marsman, Philippe A E G Delespaul, Jim van Os, Richel Lousberg
BACKGROUND: Routine Outcome Monitoring (ROM) should provide a dynamic, within-treatment forward feedback loop to guide individual treatment decisions across diagnostic categories. It has been suggested that the Experience Sampling Method (ESM), capturing the film of daily life adaptive processes, offers a flexible, personalised and transdiagnostic feedback system for monitoring and adapting treatment strategies. This is the first study that uses an ESM application (the PsyMate™) as a routine mobile-ROM (mROM) tool in an ambulatory mental health setting...
2017: PloS One
https://www.readbyqxmd.com/read/28861657/the-interplay-of-psychosis-and-victimisation-across-the-life-course-a-prospective-study-in-the-general-population
#3
Steven Honings, Marjan Drukker, Margreet Ten Have, Ron de Graaf, Saskia van Dorsselaer, Jim van Os
PURPOSE: Psychosis has been associated with adult victimisation. However, it remains unclear whether psychosis predicts incident adult victimisation, or whether adult victimisation predicts incident psychosis. Furthermore, a moderating effect of childhood victimisation on the association between psychosis and adult victimisation has not been investigated. METHODS: The longitudinal association between baseline psychotic experiences and six-year incidence of adult victimisation was assessed in a prospective general population cohort of 6646 adults using logistic regression analysis...
November 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28851542/an-experience-sampling-study-on-the-ecological-validity-of-the-swn-20-indication-that-subjective-well-being-is-associated-with-momentary-affective-states-above-and-beyond-psychosis-susceptibility
#4
Karin Pos, Iris E de Wit, Floor A van Dijk, Agna A Bartels-Velthuis, Richard Bruggeman, Carin J Meijer, Lieuwe de Haan, Berhooz Z Alizadeh, Agna A Bartels-Velthuis, Nico J Van Beveren, Richard Bruggeman, Wiepke Cahn, Lieuwe de Haan, Phillipe Delespaul, Carin J Meijer, Inez Myin-Germeys, Rene S Kahn, Frederike Schirmbeck, Claudia J P Simons, Neeltje E van Haren, Jim van Os, Ruud van Winkel
Subjective well-being (SWB) is associated with treatment adherence and symptom outcome in people with psychotic disorders. Also, it is associated with psychosis susceptibility and it is partly hereditable. The SWN-20 is a widely used tool to assess subjective well-being in patients; it was also found to be suitable for assessing SWB in healthy populations. Yet it is unclear how this retrospectively measured construct may be associated with momentary affective state, which is the proposed underlying mechanism of subjective well-being...
December 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28841828/blink-rate-is-associated-with-drug-induced-parkinsonism-in-patients-with-severe-mental-illness-but-does-not-meet-requirements-to-serve-as-a-clinical-test-the-curacao-extrapyramidal-syndromes-study-xiii
#5
Charlotte L Mentzel, P Roberto Bakker, Jim van Os, Marjan Drukker, Glenn E Matroos, Marina A J Tijssen, Peter N van Harten
BACKGROUND: Drug-induced parkinsonism (DIP) has a high prevalence and is associated with poorer quality of life. To find a practical clinical tool to assess DIP in patients with severe mental illness (SMI), the association between blink rate and drug-induced parkinsonism (DIP) was assessed. METHODS: In a cohort of 204 SMI patients receiving care from the only mental health service of the previous Dutch Antilles, blink rate per minute during conversation was assessed by an additional trained movement disorder specialist...
August 25, 2017: Journal of Negative Results in Biomedicine
https://www.readbyqxmd.com/read/28832672/white-noise-speech-illusion-and-psychosis-expression-an-experimental-investigation-of-psychosis-liability
#6
Lotta-Katrin Pries, Sinan Guloksuz, Claudia Menne-Lothmann, Jeroen Decoster, Ruud van Winkel, Dina Collip, Philippe Delespaul, Marc De Hert, Catherine Derom, Evert Thiery, Nele Jacobs, Marieke Wichers, Claudia J P Simons, Bart P F Rutten, Jim van Os
BACKGROUND: An association between white noise speech illusion and psychotic symptoms has been reported in patients and their relatives. This supports the theory that bottom-up and top-down perceptual processes are involved in the mechanisms underlying perceptual abnormalities. However, findings in nonclinical populations have been conflicting. OBJECTIVES: The aim of this study was to examine the association between white noise speech illusion and subclinical expression of psychotic symptoms in a nonclinical sample...
2017: PloS One
https://www.readbyqxmd.com/read/28782974/real-life-validation-of-reduced-reward-processing-in-emerging-adults-with-depressive-symptoms
#7
Jindra Myrthe Bakker, Liesbet Goossens, Iris Lange, Stijn Michielse, Koen Schruers, Ritsaert Lieverse, Machteld Marcelis, Thérèse van Amelsvoort, Jim van Os, Inez Myin-Germeys, Marieke Wichers
Subclinical symptoms of depression are common in emerging adults. Anhedonia is one such symptom that specifically puts one at risk for developing clinical depression. Recently, important progress has been made in elucidating the underlying neurobiology of anhedonia. This progress rests on many experimental studies examining how subjects with depressive symptoms respond to anticipating and consuming rewarding stimuli. Translating these findings to real-life reward processing dynamics is an important next step in order to guide fine-tuning of preventive treatments...
August 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28721742/mindfulness-based-stress-reduction-in-middle-aged-and-older-adults-with-memory-complaints-a-mixed-methods-study
#8
Lotte Berk, Rafke Hotterbeekx, Jim van Os, Martin van Boxtel
OBJECTIVES: In a rapidly aging world population, an increasingly large group faces age-related decline in cognitive functioning. Cognitive complaints of older adults are often related to worries and concerns associated with age-related functional decline. Mindfulness-Based Stress Reduction (MBSR) can successfully target stress, worry and ruminative thinking, but the applicability of this method in middle-aged and older adults with memory complaints is unclear. METHOD: Patients of a university hospital memory clinic (n = 13), aged 45-85 years, with memory complaints but no diagnosis of cognitive disorder, participated in a standard 8-week MBSR program, consisting of weekly group meetings and a one-day silent retreat...
July 19, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28709907/the-details-of-structural-disconnectivity-in-psychotic-disorder-a-family-based-study-of-non-fa-diffusion-weighted-imaging-measures
#9
Stijn Michielse, Ed Gronenschild, Patrick Domen, Jim van Os, Machteld Marcelis
BACKGROUND: Diffusion Tensor Imaging (DTI) studies in psychotic disorder have shown reduced FA, often interpreted as disturbed white matter integrity. The observed 'dysintegrity' may be of multifactorial origin, as changes in FA are thought to reflect a combination of changes in myelination, fiber organization and number of axons. Examining the structural substrate of the diffusion tensor in individuals with (risk for) psychotic disorder may provide better understanding of the underlying structural changes...
July 11, 2017: Brain Research
https://www.readbyqxmd.com/read/28690921/risk-factors-for-tremor-in-a-population-of-patients-with-severe-mental-illness-an-18-year-prospective-study-in-a-geographically-representative-sample-the-curacao-extrapyramidal-syndromes-study-xi
#10
Charlotte L Mentzel, P Roberto Bakker, Jim van Os, Marjan Drukker, Michiel R H van den Oever, Glenn E Matroos, Hans W Hoek, Marina Aj Tijssen, Peter N van Harten
BACKGROUND: The aim was to assess incidence, prevalence and risk factors of medication-induced tremor in African-Caribbean patients with severe mental illness (SMI). METHOD: A prospective study of SMI patients receiving care from the only mental health service of the previous Dutch Antilles. Eight clinical assessments, over 18 years, focused on movement disorders, medication use, and resting tremor (RT) and (postural) action tremor (AT). Risk factors were modeled with logistic regression for both current (having) tremor and for tremor at the next time point (developing)...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28666366/child-maltreatment-and-clinical-outcome-in-individuals-at-ultra-high-risk-for-psychosis-in-the-eu-gei-high-risk-study
#11
Tamar C Kraan, Eva Velthorst, Manouk Themmen, Lucia Valmaggia, Matthew J Kempton, Phillip McGuire, Jim van Os, Bart P F Rutten, Filip Smit, Lieuwe de Haan, Mark van der Gaag
Background: Child maltreatment has been associated with a wide range of mental disorders in adulthood. Whether child maltreatment is specifically associated with psychosis risk in individuals at ultra-high risk (UHR) for psychosis, or leads to a general vulnerability for overall psychopathology in the UHR stage remains unclear. The present study examines the association between child maltreatment and transition to psychosis and other mental disorders. Methods: The sample consisted of 259 UHR individuals from the EUropean network of national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) study...
June 28, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28647453/national-funding-for-mental-health-research-in-finland-france-spain-and-the-united-kingdom
#12
Jean-Baptiste Hazo, Coralie Gandré, Marion Leboyer, Carla Obradors-Tarragó, Stefano Belli, David McDaid, A-La Park, Maria Victoria Maliandi, Kristian Wahlbeck, Til Wykes, Jim van Os, Josep Maria Haro, Karine Chevreul
As part of the Roamer project, we aimed at revealing the share of health research budgets dedicated to mental health, as well as on the amounts allocated to such research for four European countries. Finland, France, Spain and the United Kingdom national public and non-profit funding allocated to mental health research in 2011 were investigated using, when possible, bottom-up approaches. Specifics of the data collection varied from country to country. The total amount of public and private not for profit mental health research funding for Finland, France, Spain and the UK was €10·2, €84·8, €16·8, and €127·6 million, respectively...
June 21, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28586480/lifetime-prevalence-and-correlates-of-schizophrenia-spectrum-affective-and-other-non-affective-psychotic-disorders-in-the-chinese-adult-population
#13
Wing Chung Chang, Corine Sau Man Wong, Eric Yu Hai Chen, Linda Chiu Wa Lam, Wai Chi Chan, Roger Man Kin Ng, Se Fong Hung, Eric Fuk Chi Cheung, Pak Chung Sham, Helen Fung Kum Chiu, Ming Lam, Edwin Ho Ming Lee, Tin Po Chiang, Lap Kei Chan, Gary Kar Wai Lau, Allen Ting Chun Lee, Grace Tak Yu Leung, Joey Shuk Yan Leung, Joseph Tak Fai Lau, Jim van Os, Glyn Lewis, Paul Bebbington
Lifetime prevalence of psychotic disorders varies widely across studies. Epidemiological surveys have rarely examined prevalences of specific psychotic disorders other than schizophrenia, and the majority used a single-phase design without employing clinical reappraisal interview for diagnostic verification. The current study investigated lifetime prevalence, correlates and service utilization of schizophrenia-spectrum, affective, and other non-affective psychotic disorders in a representative sample of community-dwelling Chinese adult population aged 16-75 years (N = 5719) based on a territory-wide, population-based household survey for mental disorders in Hong Kong...
October 21, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28566951/psychological-and-biological-validation-of-a-novel-digital-social-peer-evaluation-experiment-digi-spee
#14
Claudia Menne-Lothmann, Jeroen Decoster, Ruud van Winkel, Dina Collip, Bart P F Rutten, Philippe Delespaul, Marc De Hert, Catherine Derom, Evert Thiery, Nele Jacobs, Jim van Os, Marieke Wichers
INTRODUCTION: Negative social evaluation is associated with psychopathology. Given the frequency of evaluation through increasingly prevalent virtual social networks, increased understanding of the effects of this social evaluation is urgently required. METHODS: A new digital social peer evaluation experiment (digi-SPEE) was developed to mimic everyday online social interactions between peers. Participants received mildly negative feedback on their appearance, intelligence, and congeniality...
March 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28544391/the-experience-sampling-method-as-an-mhealth-tool-to-support-self-monitoring-self-insight-and-personalized-health-care-in-clinical-practice
#15
Jim van Os, Simone Verhagen, Anne Marsman, Frenk Peeters, Maarten Bak, Machteld Marcelis, Marjan Drukker, Ulrich Reininghaus, Nele Jacobs, Tineke Lataster, Claudia Simons, Richel Lousberg, Sinan Gülöksüz, Carsten Leue, Peter C Groot, Wolfgang Viechtbauer, Philippe Delespaul
BACKGROUND: The experience sampling method (ESM) builds an intensive time series of experiences and contexts in the flow of daily life, typically consisting of around 70 reports, collected at 8-10 random time points per day over a period of up to 10 days. METHODS: With the advent of widespread smartphone use, ESM can be used in routine clinical practice. Multiple examples of ESM data collections across different patient groups and settings are shown and discussed, varying from an ESM evaluation of a 6-week randomized trial of mindfulness, to a twin study on emotion dynamics in daily life...
June 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28498576/a-critique-of-the-ultra-high-risk-and-transition-paradigm
#16
Jim van Os, Sinan Guloksuz
The transdiagnostic expression of psychotic experiences in common mental disorder (anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a small minority of people may indeed develop a clinical picture that meets criteria for schizophrenia. However, it appears neither useful nor valid to observe early states of multidimensional psychopathology in young people through the "schizo"-prism, and apply misleadingly simple, unnecessary and inefficient binary concepts of "risk" and "transition"...
June 2017: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/28416093/the-role-of-cognitive-functioning-in-the-relationship-between-childhood-trauma-and-a-mixed-phenotype-of-affective-anxious-psychotic-symptoms-in-psychotic-disorders
#17
Giovanni Mansueto, Martine van Nierop, Koen Schruers, Berhooz Z Alizadeh, Agna A Bartels-Velthuis, Nico J van Beveren, Richard Bruggeman, Wiepke Cahn, Lieuwe de Haan, Philippe Delespaul, Carin J Meijer, Inez Myin-Germeys, Rene S Kahn, Frederike Schirmbeck, Claudia J P Simons, Neeltje E M van Haren, Jim van Os, Ruud van Winkel
Cognitive impairments in patients with psychotic disorder have been associated with poor functioning and increased symptom severity. Furthermore, childhood trauma (CT) exposure has been associated with worse cognitive functioning as well as co-occurrence of affective-anxious-psychosis symptoms or a 'mixed phenotype of psychopathology' (MP), which in turn is associated with greater symptom severity, and poor functioning. This study aims to evaluate if cognition could be associated with CT/MP. 532 patients with non-affective psychotic patients were assessed on CT, symptom profile, cognition, functioning, and symptom severity at baseline and 3 and 6-year follow-up...
April 13, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28358925/serum-s100b-a-proxy-marker-for-grey-and-white-matter-status-in-the-absence-and-presence-of-increased-risk-of-psychotic-disorder
#18
Christine van der Leeuw, Sanne Peeters, Ed Gronenschild, Stijn Michielse, Marcel Verbeek, Paul Menheere, Jim van Os, Machteld Marcelis
S100B is a protein with dose-dependent neurotrophic and neurotoxic effects. Whether S100B in psychotic disorder mirrors pathophysiological mechanisms (which elicit exacerbation of disease) or compensatory action is unclear, as is its validity as a proxy marker for brain status. Insight may be gained by examining associations between serum S100B and indices of grey (cortical thickness (CT)) and white matter (fractional anisotropy (FA)), in relation to the absence or presence of (increased risk of) psychotic disorder...
2017: PloS One
https://www.readbyqxmd.com/read/28220586/prevalence-of-anxiety-and-depressive-symptoms-and-their-association-with-pelvic-floor-dysfunctions-a-cross-sectional-cohort-study-at-a-pelvic-care-centre
#19
Desiree Vrijens, Bary Berghmans, Fred Nieman, Jim van Os, Gommert van Koeveringe, Carsten Leue
AIMS: Pelvic floor dysfunctions (PFDs), like voiding complaints, urinary and fecal incontinence, and prolapse, are prevalent and associated with decrease in quality of life. PFDs are often complex and multifactorial in origin showing interrelationships between different PFD and with affective conditions. The primary aim of this study is to describe the prevalence of affective complaints in a cohort of Pelvic Care Centre (PCC) patients. The secondary aim is to describe associations between PFDs and depression or anxiety...
September 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28204708/modeling-the-interplay-between-psychological-processes-and-adverse-stressful-contexts-and-experiences-in-pathways-to-psychosis-an-experience-sampling-study
#20
Annelie Klippel, Inez Myin-Germeys, UnYoung Chavez-Baldini, Kristopher J Preacher, Matthew Kempton, Lucia Valmaggia, Maria Calem, Suzanne So, Stephanie Beards, Kathryn Hubbard, Charlotte Gayer-Anderson, Adanna Onyejiaka, Marieke Wichers, Philip McGuire, Robin Murray, Philippa Garety, Jim van Os, Til Wykes, Craig Morgan, Ulrich Reininghaus
Several integrated models of psychosis have implicated adverse, stressful contexts and experiences, and affective and cognitive processes in the onset of psychosis. In these models, the effects of stress are posited to contribute to the development of psychotic experiences via pathways through affective disturbance, cognitive biases, and anomalous experiences. However, attempts to systematically test comprehensive models of these pathways remain sparse. Using the Experience Sampling Method in 51 individuals with first-episode psychosis (FEP), 46 individuals with an at-risk mental state (ARMS) for psychosis, and 53 controls, we investigated how stress, enhanced threat anticipation, and experiences of aberrant salience combine to increase the intensity of psychotic experiences...
March 1, 2017: Schizophrenia Bulletin
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