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Nut allergy

M N Kim, K E Lee, J Y Hong, K W Kim, K-E Kim, M H Sohn, J W Park
BACKGROUND: Peanut allergies are common and can be life-threating for sensitised individuals. Peanut allergens share significant amino acid homology with those of other legumes and tree nuts, but their cross-reactivity still remains unclear. OBJECTIVE: We sought to determine the clinical significance of the cross-reactivity of peanut allergens with those of walnut and soybean. METHODS: Pooled sera from eight subjects with both peanut and walnut specific IgE were investigated in an inhibition test...
October 7, 2016: Allergologia et Immunopathologia
T Banti, A Carsin, B Chabrol, R Reynaud, A Fabre
: Infant food diversification has undergone a rapid succession of good practice recommendations in France, but there has been no assessment of pediatrician practices on food diversification. OBJECTIVE: To assess the practices of pediatricians in relation to current recommendations of the French Society of Pediatrics on infant food diversification. METHODS: This was an observational study conducted from 1 November 2014 to 31 March 2015. The study population consisted of 97 pediatricians in the Var department and 84 pediatric residents assigned to the University of Aix-Marseille in France...
October 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Stephanie Stojanovic, Celia Mary Zubrinich, Robyn O'Hehir, Mark Hew
No abstract text is available yet for this article.
September 19, 2016: Medical Journal of Australia
Aneta Wagner, Angelika Szwed, Krzysztof Buczyłko, Waldemar Wagner
BACKGROUND: Oral allergy syndrome (OAS) is caused by cross-reacting allergens found in pollen, raw fruits, vegetables, and some tree nuts. The major apple allergen, Mal d 1, is a cause of food allergic reactions in birch pollen sensitized patients. OBJECTIVE: To explore the allergenicity of the most popular and commonly consumed apple cultivars in Poland in patients with birch pollen allergy with or without OAS. METHODS: Data were obtained from 46 adults with clinical symptoms of birch allergy and allergic rhinitis or rhinoconjunctivitis...
October 2016: Annals of Allergy, Asthma & Immunology
J Sánchez-López, V Gázquez, N Rubira, L Valdesoiro, M Guilarte, A Garcia-Moral, N Depreux, L Soto-Retes, M De Molina, O Luengo, R Lleonart, M Basagaña
BACKGROUND: Food allergy affects around 6% of the European population and its prevalence worldwide has been increasing in the last decades, but studies focused on investigating food allergy epidemiology in Europe are lacking. OBJECTIVE: The Cibus project was created to register the main culprit foods and their clinical manifestations in food allergic patients in Catalonia. METHODS: A specific online database was designed. Allergists from eight different Catalan hospitals registered the new diagnoses of food allergy...
August 31, 2016: Allergologia et Immunopathologia
Robin Korte, Jens Brockmeyer
Food allergies have become a global challenge to food safety in industrialized countries in recent years. With governmental monitoring and legislation moving towards the establishment of threshold allergen doses, there is a need for sensitive and quantitative analytical methods for the determination of allergenic food contaminants. Targeted proteomics employing liquid chromatography-mass spectrometry (LC-MS) has emerged as a promising technique that offers increased specificity and reproducibility compared to antibody and DNA-based technologies...
November 2016: Analytical and Bioanalytical Chemistry
Cíntia Mendes, Joana Costa, António A Vicente, Maria Beatriz P P Oliveira, Isabel Mafra
Cashew plant (Anacardium occidentale L.) is the most relevant species of the Anacardium genus. It presents high economic value since it is widely used in human nutrition and in several industrial applications. Cashew nut is a well-appreciated food (belongs to the tree nut group), being widely consumed as snacks and in processed foods by the majority of world's population. However, cashew nut is also classified as a potent allergenic food known to be responsible for triggering severe and systemic immune reactions (e...
September 1, 2016: Clinical Reviews in Allergy & Immunology
Brooke I Polk, Deendayal Dinakarpandian, Maya Nanda, Charles Barnes, Chitra Dinakar
BACKGROUND: Coconut (Cocos nucifera), despite being a drupe, was added to the US Food and Drug Administration list of tree nuts in 2006, causing potential confusion regarding the prevalence of coconut allergy among tree nut allergic patients. OBJECTIVE: To determine whether sensitization to tree nuts is associated with increased odds of coconut sensitization. METHODS: A single-center retrospective analysis of serum specific IgE levels to coconut, tree nuts (almond, Brazil nut, cashew, chestnut, hazelnut, macadamia, pecan, pistachio, and walnut), and controls (milk and peanut) was performed using deidentified data from January 2000 to August 2012...
October 2016: Annals of Allergy, Asthma & Immunology
Johanna P M van der Valk, Roy Gerth van Wijk, Yvonne Vergouwe, Ewout W Steyerberg, Marit Reitsma, Harry J Wichers, Huub F J Savelkoul, Berber Vlieg-Boerstra, Hans de Groot, Anthony E J Dubois, Nicolette W de Jong
BACKGROUND: The double-blind, placebo-controlled food challenge test (DBPCFC) is the gold standard in cashew nut allergy. This test is costly, time-consuming and not without side effects. Analysis of IgE-reactivity to cashew nut components may reduce the need for food challenge tests. METHODS: In a prospective and multicentre study, children with suspected cashew nut allergy underwent a DBPCFC with cashew nut. Specific IgE to cashew nut and to the components Ana o 1, 2 and 3 were determined...
August 11, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Carlos Lozoya-Ibáñez, Sara Morgado-Nunes, Alexandra Rodrigues, Cláudia Lobo, Luis Taborda-Barata
BACKGROUND: Only one previous study, via telephone call, on the prevalence of self-reported food allergies has been performed in Portugal, in a small sample of adults. The objective of this study was to determine the prevalence of self-reported and probable food allergy, analyze the clinical features and involved foods in Portuguese adults. METHODS: Population-based, cross-sectional study performed in various healthcare centres from central Portugal. All 1436 randomly selected individuals (median age: 45 years, 50...
2016: Allergy, Asthma, and Clinical Immunology
J P M van der Valk, R Gerth van Wijk, B M J Flokstra-de Blok, J L van der Velde, H de Groot, H J Wichers, A E J Dubois, N W de Jong
BACKGROUND: Previous studies showed that Health-Related Quality of Life (HRQL) significantly improved after the food challenge, with greater improvements in HRQL after a negative outcome than a positive outcome. It is currently unknown whether this also occurs in patients undergoing DBPCFCs with cashew nut in the context of a clinical trial. METHODS: Quality of life was studied in children enrolled in a cashew nut study using food allergy quality of life questionnaires (FAQLQs)...
August 6, 2016: Pediatric Allergy and Immunology
M Ponce, S C Diesner, Z Szépfalusi, T Eiwegger
IgE-mediated reactions to food allergens are the most common cause of anaphylaxis in childhood. Although allergies to cow's milk, egg, or soy proteins, in contrast to peanut and tree nut allergens, resolve within the first 6 years of life in up to 60% due to natural tolerance development, this process is not well understood. At present, there is no cure or treatment for food allergy that would result in an induction of tolerance to the symptom-eliciting food. Avoidance, providing an emergency plan and education, is the standard of treatment...
October 2016: Allergy
Nedeljko Radlović, Zoran Leković, Vladimir Radlović, Dusica Simić, Dragana Ristić, Biljana Vuletić
Food allergy represents a highly up-to-date and continually increasing problem of modern man. Although being present in all ages, it most often occures in children aged up to three years. Sensitization most often occurs by a direct way, but it is also possible to be caused by mother's milk, and even transplacentally. Predisposition of inadequate immune response to antigen stimulation, reaginic or nonreaginic, is of non-selective character so that food allergy is often multiple and to a high rate associated with inhalation and/or contact hypersensitivity...
January 2016: Srpski Arhiv za Celokupno Lekarstvo
N Lomidze, T Abramidze, T Gotua, N Dolidze, M Gotua
The aim of our study was to investigate sensitization pattern to food allergens in different age groups of atopic patients in Georgia and reveal the associations between food sensitization and clinical manifestations of allergic disease reflecting the development of atopic march. 1000 patients (children-783, adult-217) with different clinical manifestations were involved in the study. Specific IgE antibodies to food mix, cow's milk, casein, egg, wheat, fish, nuts mixture and inhalant allergens were measured by using ImmunoCap (Phadia, Uppsala, Sweden)...
April 2016: Georgian Medical News
Thomas Werfel
Food allergies can newly arise in adulthood or persist following a food allergy occurring in childhood. The prevalence of primary food allergy is basically higher in children than in adults; however, in the routine practice food allergies in adulthood appear to be increasing and after all a prevalence in Germany of 3.7 % has been published. The clinical spectrum of manifestations of food allergies in adulthood is broad. Allergy symptoms of the immediate type can be observed as well as symptoms occurring after a delay, such as indigestion, triggering of hematogenous contact eczema or flares of atopic dermatitis...
June 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Sai Kranthi Vanga, Vijaya Raghavan
"Tree nut" is a broad term for classification of nuts that include cashews, almonds, hazelnuts etc. Reports of mild to adverse immune reactions following the consumption of these nuts has been on a rise in recent years. Currently, about 1.2 - 2% of the world's population suffer from sensitivity to tree nuts. The only solution is complete abstinence from the allergy causing tree nut which is not feasible in most cases due to issues like cross contamination or their presence in the form of hidden ingredients in processed foods...
May 12, 2016: Critical Reviews in Food Science and Nutrition
Julian Azofra, Felicia Berroa, Gabriel Gastaminza, Noemi Saiz, Pedro M Gamboa, Catalina Vela, Blanca E García, Susana Lizarza, Miguel Angel Echenagusia, Alejandro Joral, María Ascensión Aranzabal, Maria Dolores Quiñones, Ignacio Jauregui, Juan F Madera, Jose Antonio Navarro, Maria Teresa Lizaso, Amalia Bernad, Maria José Goikoetxea
BACKGROUND: Plant food allergies associated with lipid transfer protein (LTP) have been widely described in the Mediterranean Basin. OBJECTIVE: The aim of this work was to describe the clinical profile and pollen sensitization of plant food- allergic patients sensitized to LTP in a non-Mediterranean area. METHODS: Patients with clear IgE-mediated symptoms associated with plant foods and a positive skin prick test (SPT) to Pru p 3 were included in a prospective study in the north of Spain...
2016: International Archives of Allergy and Immunology
L D Archila, I-T Chow, J W McGinty, A Renand, D Jeong, D Robinson, M L Farrington, W W Kwok
BACKGROUND: Allergies to cashew are increasing in prevalence, with clinical symptoms ranging from oral pruritus to fatal anaphylactic reaction. Yet, cashew-specific T cell epitopes and T cell cross-reactivity amongst cashew and other tree nut allergens in humans remain uncharacterized. OBJECTIVES: In this study, we characterized cashew-specific T cell responses in cashew-allergic subjects and examined cross-reactivity of these cashew-specific cells towards other tree nut allergens...
June 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Yuzhu Zhang, BoRam Lee, Wen-Xian Du, Shu-Chen Lyu, Kari C Nadeau, Larry J Grauke, Yan Zhang, Shuo Wang, Yuting Fan, Jiang Yi, Tara H McHugh
The 7S vicilin and 11S legumin seed storage globulins belong to the cupin protein superfamily and are major food allergens in many foods from the "big eight" food allergen groups. Here, for the first time, pecan vicilin was found to be a food allergen. Western blot experiments revealed that 30% of 27 sera used in this study and 24% of the sera from 25 patients with double-blind, placebo controlled clinical pecan allergy contained IgE antibodies specific to pecan vicilin. This allergen consists of a low-complexity region at its N-terminal and a structured domain at the C-terminal that contains two cupin motifs and forms homotrimers...
May 25, 2016: Journal of Agricultural and Food Chemistry
Nannan Jiang, Jia Yin, Liping Wen, Hong Li
PURPOSE: Comprehensive evaluation of anaphylaxis in China is currently lacking. In this study, we characterized the clinical profiles, anaphylactic triggers, and emergency treatment in pediatric and adult patients. METHODS: Outpatients diagnosed with "anaphylaxis" or "severe allergic reactions" in the Department of Allergy, Peking Union Medical College Hospital from January 1, 2000 to June 30, 2014 were analyzed retrospectively. RESULTS: A total of 1,952 episodes of anaphylaxis in 907 patients were analyzed (78% were adults and 22% were children)...
July 2016: Allergy, Asthma & Immunology Research
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