keyword
MENU ▼
Read by QxMD icon Read
search

HsTnT

keyword
https://www.readbyqxmd.com/read/29619842/high-sensitivity-cardiac-troponin-t-for-diagnosis-of-nstemi-in-the-elderly-emergency-department-patient-a-clinical-cohort-study
#1
Dorothee Riedlinger, Martin Möckel, Christian Müller, Fabian Holert, Julia Searle, Johannes von Recum, Anna Slagman
PURPOSE: The aim of this study is to evaluate the impact of age on the diagnostic performance of high-sensitivity troponin T (hsTnT) under routine conditions. MATERIALS AND METHODS: Data of 4118 consecutive emergency department (ED) patients who underwent a routine TnT measurement between 11 October 2012 and 30 November 2013 were analysed. Diagnostic accuracy of hsTnT was compared in four age categories (<50, 50-64, 65-74, ≥75 years of age) for different cut-off values...
April 18, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29599188/prognostic-impact-of-copeptin-in-pulmonary-embolism-a-multicentre-validation-study
#2
Kristian Hellenkamp, Piotr Pruszczyk, David Jiménez, Anna Wyzgał, Deisy Barrios, Michał Ciurzyński, Raquel Morillo, Lukas Hobohm, Karsten Keller, Katarzyna Kurnicka, Maciej Kostrubiec, Rolf Wachter, Gerd Hasenfuß, Stavros Konstantinides, Mareike Lankeit
To externally validate the prognostic impact of copeptin, either alone or integrated in risk stratification models, in pulmonary embolism (PE), we performed a post-hoc analysis of 843 normotensive PE patients prospectively included in three European cohorts.Within the first 30 days, 21 (2.5;95%CI,1.5-3.8%) patients had an adverse outcome and 12 (1.4;95%CI,0.7-2.5%) died due to PE. Patients with copeptin ≥24 pmol·L-1 had a 6.3-fold increased risk for an adverse outcome (95%CI,2.6-15.5;p<0.001) and a 7...
March 29, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29589418/myocardial-injury-after-non-cardiac-surgery-a-perioperative-affair
#3
Viviana Miccichè, Cesare Baldi, Edoardo DE Robertis, Ornella Piazza
Myocardial injury after non cardiac surgery (MINS) is a rather new nosological entity and an unfortunately common perioperative complication. The diagnostic criteria for MINS, also indicated as isolated myocardi- al injury (IMI), are an elevated postoperative high sensitivity Troponin T (hsTnT level ranging between 20 and 65 ng/L with an absolute change of at least 5 ng/L or hsTnT level > 65 ng/L), in absence of symptoms and/or EKG findings suggestive of ischemia and without a non ischemic aetiology causing Troponin eleva- tion...
March 27, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29580830/myocardial-injury-is-more-common-than-deep-venous-thrombosis-after-vascular-surgery-and-is-associated-with-a-high-one-year-mortality-risk
#4
Jacek Górka, Kamil Polok, Jakub Fronczek, Karolina Górka, Mateusz Kózka, Paweł Iwaszczuk, Marzena Frołow, P J Devereaux, Bruce Biccard, Jacek Musiał, Wojciech Szczeklik
OBJECTIVE/BACKGROUND: Venous thromboembolism (VTE) has been considered the dominant major life threatening vascular complication after non-cardiac surgery, but recent studies have shifted the emphasis toward myocardial injury after non-cardiac surgery (MINS) as a common adverse event in the peri-operative setting. The aim of the present study was to compare the incidence and influence on mortality of two dominant venous and arterial events in the peri-operative period by prospectively screening a consecutive cohort of patients undergoing vascular surgery...
March 23, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29559697/pacemaker-implantation-associated-myocardial-micro-damage-a-randomised-comparison-between-active-and-passive-fixation-leads
#5
Patrick Blažek, Jerko Ferri-Certić, Hrvoje Vražić, Carsten Lennerz, Christian Grebmer, Kazuaki Kaitani, Martin Karch, Boris Starčević, Verena Semmler, Christof Kolb
Fixation of the pacemaker leads during pacemaker implantation leads to an increase of cardiac Troponin T (cTnT) that can be interpreted as a sign of minimal myocardial damage. This trial evaluates whether the mechanism type of lead fixation influences the magnitude of cTnT release. Patients having a de-novo cardiac pacemaker implantation or a lead revision were centrally randomized to receive either a ventricular lead with an active (screw) or passive (tine) fixation mechanism. High-sensitive Troponin T (hsTnT) was determined on the day of the procedure beforehand and on the following day...
March 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29544658/impact-of-internal-and-external-electrical-cardioversion-on-cardiac-specific-enzymes-and-inflammation-in-patients-with-atrial-fibrillation-and-heart-failure
#6
Philipp Stieger, Obaida R Rana, Erol Saygili, Haschmatulla Zazai, Thomas Rauwolf, Conrad Genz, Rajen Bali, Ruediger C Braun-Dullaeus, Samir M Said
BACKGROUND: Implantable cardioverter/defibrillator (ICD) shocks can cause myocardial injury, contributing to the progression of the underlying heart disease. The aim was to evaluate whether internal electrical cardioversion (int-CV) via the ICD or conventional external CV (ext-CV) of persistent atrial fibrillation (AF) in heart failure (HF) patients induces myocardial injury and initiates inflammation. METHODS AND RESULTS: A total of 115 HF patients with an ejection fraction between 20% and 45% were prospectively enrolled...
March 12, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29514145/preoperative-midrregional-proadrenomedulin-and-high-sensitivity-troponin-t-predict-perioperative-cardiovascular-events-in-non-cardiac-surgery
#7
Mladjan Golubovic, Radmilo Jankovic, Dusan Sokolovic, Vladan Cosic, Vesna Maravic, Tomislav Kostic, Zoran Perisic, Nebojsa Ladjevic
OBJECTIVE: We evaluated the utility of preoperative mid-regional pro-adrenomedulin (MR-proADM) and cardiac troponin T (TnT) for improved detection of patients at high risk for perioperative cardiac events and mortality after major non-cardiac surgery. SUBJECTS AND METHODS: This prospective, single-center, observational study enrolled 79 patients undergoing major non-cardiac surgery. After initial clinical assessment (clinical history, physical examination, echocardiogram, blood tests, and chest X-ray), mid-regional pro-adrenomedulin and high sensitivity troponin T (hsTnT) were measured within 48 hours prior to surgery by immunoluminometric and electrochemiluminescence-immuno assay...
March 7, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29481724/incidence-predictors-and-longer-term-impact-of-troponin-elevation-following-hybrid-chronic-total-occlusion-percutaneous-coronary-intervention
#8
Rustem Dautov, Luiz Fernando Ybarra, Can Manh Nguyen, Claire Gibrat, Dominique Joyal, Stéphane Rinfret
OBJECTIVES: We examined the incidence of periprocedural cardiac enzyme rise (PCER) [troponin T (TnT) or high-sensivity (hs)TnT >5× the upper limit of normal (ULN)] and periprocedural myocardial infarction (PMI), predictors of PCER and impact of PCER on the longer-term major adverse cardiac events (MACE) following hybrid chronic total occlusion (CTO) percutaneous coronary intervention (PCI). BACKGROUND: PCER and PMI after CTO PCI, risk factors for PCER and its impact on longer-term MACE are not fully understood...
February 26, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29480016/a-direct-comparison-of-decision-rules-for-early-discharge-of-suspected-acute-coronary-syndromes-in-the-era-of-high-sensitivity-troponin
#9
Pei Gee Chew, Fredrick Frost, Liam Mullen, Michael Fisher, Heidar Zadeh, Ruth Grainger, Khaled Albouaini, James Dodd, Bilal Patel, Periaswamy Velavan, Babu Kunadian, Anju Rawat, Toba Obafemi, Sarah Tong, Julia Jones, Aleem Khand
BACKGROUND: We tested the hypothesis that a single high sensitivity troponin at limits of detection (LOD HSTnT) (<5 ng/l) combined with a presentation non-ischaemic electrocardiogram is superior to low-risk Global Registry of Acute Coronary Events (GRACE) (<75), Thrombolysis in Myocardial Infarction (TIMI) (≤1) and History, ECG, Age, Risk factors and Troponin (HEART) score (≤3) as an aid to early, safe discharge for suspected acute coronary syndrome. METHODS: In a prospective cohort study, risk scores were computed in consecutive patients with suspected acute coronary syndrome presenting to the Emergency Room of a large English hospital...
February 1, 2018: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29466220/-head-to-head-comparison-of-suppression-of-tumorogenicity-2-and-copeptin-significance-for-prognosis-of-patients-after-acute-heart-failure-decompensation
#10
O Y Narusov, D E Koshkina, V N Protasov, A A Skvortsov, V P Masenko, S N Tereshchenko, Y F Osmolovskaya, T V Kuznetsova
PURPOSE: To assess the suppression of tumorogenicity 2 (ST2) and copeptin significance for risk stratification of patient (pts) with acute decompensated heart failure (ADHF) during long-term follow-up compared with traditional risk factors. METHODS: We included in a prospective study 159 pts with ADHF. Blood samples to determine copeptin, sST2, NT-proBNP and hsTnT concentration were collected at admission and at discharge from the hospital. Serial determination of biomarker concentration was performed at 3, 6 and 12 months of follow-up...
September 2017: Kardiologiia
https://www.readbyqxmd.com/read/29458232/fibrinogen-and-neopterin-is-associated-with-future-myocardial-infarction-and-total-mortality-in-patients-with-stable-coronary-artery-disease
#11
Øistein Rønneberg Mjelva, Gard F T Svingen, Eva K R Pedersen, Reinhard Seifert, Jan Terje Kvaløy, Øivind Midttun, Per M Ueland, Jan E Nordrehaug, Ottar Nygård, Dennis W T Nilsen
Systemic fibrinogen and neopterin are related to inflammation. We investigated the prognostic utility and possible interactions of these biomarkers in stable coronary artery disease (SCAD) patients undergoing coronary angiography. We included 3,545 patients with suspected stable angina with a median follow-up of 7.3 and 10.2 years for incident acute myocardial infarction (AMI) and all-cause mortality, respectively. Prospective associations were explored by Cox regression. Potential effect modifications were investigated according to strata of fibrinogen, neopterin or high-sensitivity troponin T (hsTnT) below and above the median, as well as gender and smoking habits...
April 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29428559/elevated-il-27-in-patients-with-acute-coronary-syndrome-is-associated-with-adverse-ventricular-remodeling-and-increased-risk-of-recurrent-myocardial-infarction-and-cardiovascular-death
#12
Helena Grufman, Troels Yndigegn, Isabel Gonçalves, Jan Nilsson, Alexandru Schiopu
BACKGROUND AND AIMS: IL-27 is an immunoregulatory cytokine belonging to the IL-6/IL-12 family that was found to be elevated in acute coronary syndrome (ACS) patients. We investigated whether IL-27 is related to post-ischemic cardiac remodeling and long-term prognosis in this patient group. METHODS: We included 524 ACS patients, defined as acute myocardial infarction (AMI) or unstable angina (UA). A subgroup of 107 patients donated blood samples 6 weeks after the index event, and underwent a follow-up echocardiographical examination at 1 year...
February 7, 2018: Cytokine
https://www.readbyqxmd.com/read/29407114/objectively-measured-physical-activity-and-cardiac-biomarkers-a-cross-sectional-population-based-study-in-older-men
#13
Tessa J Parsons, Claudio Sartini, Paul Welsh, Naveed Sattar, Sarah Ash, Lucy T Lennon, S Goya Wannamethee, I-Min Lee, Peter H Whincup, Barbara J Jefferis
BACKGROUND: N-terminal pro-brain natriuretic peptide (NT-proBNP) and high sensitivity Troponin T (hsTnT) are markers of cardiac injury used in diagnosis of heart failure and myocardial infarction respectively, and associated with increased risk of cardiovascular disease. Since physical activity is protective against cardiovascular disease and heart failure, we investigated whether higher levels of physical activity, and less sedentary behaviour were associated with lower NT-proBNP and hsTnT...
March 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29397141/prognostic-value-of-postoperative-high-sensitivity-troponin-t-in-patients-with-different-stages-of-kidney-disease-undergoing-noncardiac-surgery
#14
V G B Liem, S E Hoeks, F Grüne, K H J M Mol, F H I M Wesdorp, R J Stolker, F van Lier
BACKGROUND: Emerging evidence suggests that postoperative troponin release is a strong and independent predictor of short-term mortality. However, evaluating elevated troponins in patients with chronic kidney disease (CKD) is still controversial and is often disregarded. This study examines morbidity along with short- and long-term mortality risk associated with elevated high-sensitivity troponin T (hsTnT) in patients with different stages CKD undergoing noncardiac surgery. METHODS: This observational cohort comprised 3262 patients aged ≥60 yr who underwent noncardiac surgery...
January 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29397140/association-between-postoperative-mean-arterial-blood-pressure-and-myocardial-injury-after-noncardiac-surgery
#15
F van Lier, F H I M Wesdorp, V G B Liem, J W Potters, F Grüne, H Boersma, R J Stolker, S E Hoeks
BACKGROUND: Myocardial injury after noncardiac surgery is common, although the exact pathophysiology is unknown. It is plausible that hypotension after surgery is relevant for the development of myocardial injury. The authors evaluated whether low mean arterial pressures (MAPs) after surgery are related to an increased incidence in postoperative cardiac-troponin elevation. METHODS: A prospective cohort of 2211 patients aged ≥60 yr, undergoing major or moderate noncardiac surgery in The Netherlands, was retrospectively analysed for the occurrence of postoperative cardiac-troponin elevation [high-sensitive troponin T (hsTnT) >14 ng L-1 ]...
January 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29394350/blood-pressure-and-cardiovascular-outcomes-in-patients-with-diabetes-and-high-cardiovascular-risk
#16
Brian A Bergmark, Benjamin M Scirica, Ph Gabriel Steg, Christina L Fanola, Yared Gurmu, Ofri Mosenzon, Avivit Cahn, Itamar Raz, Deepak L Bhatt
Aims: Optimal blood pressure for prevention of cardiovascular (CV) events in patients with Type 2 diabetes mellitus (T2DM) remains uncertain and there is concern for increased risk with low diastolic blood pressure (DBP). This study analysed the association between blood pressure and CV outcomes in high-risk patients with T2DM. Methods and results: Patients with T2DM and elevated CV risk were enrolled in the Saxagliptin Assessment of Vascular Outcomes Recorded in patients with diabetes mellitus-Thrombolysis in Myocardial Infarction 53 trial...
January 31, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29386197/growth-differentiation-factor-15-is-a-new-biomarker-for-survival-and-renal-outcomes-in-light-chain-amyloidosis
#17
Efstathios Kastritis, Ioannis Papassotiriou, Giampaolo Merlini, Paolo Milani, Evangelos Terpos, Marco Basset, Athanasios Akalestos, Francesca Russo, Erasmia Psimenou, Filia Apostolakou, Maria Roussou, Maria Gavriatopoulou, Evangelos Eleutherakis-Papaiakovou, Despina Fotiou, Dimitrios C Ziogas, Elektra Papadopoulou, Constantinos Pamboucas, Meletios A Dimopoulos, Giovanni Palladini
Growth differentiation factor-15 (GDF-15) improves prognostication in patients with cardiovascular disorders in addition to conventional cardiac markers (N-terminal pro B-type natriuretic peptide [NT-proBNP], troponins [Tns]) and has shown prognostic value in patients with renal diseases. In patients with light chain (AL) amyloidosis, cardiac involvement is the major determinant of prognosis, and cardiac markers define prognosis, whereas biomarkers of renal involvement stratify renal risk. We explored the prognostic importance of serum level of GDF-15 in patients with AL amyloidosis in 2 independent cohorts...
April 5, 2018: Blood
https://www.readbyqxmd.com/read/29380285/stronger-correlation-with-myocardial-ischemia-of-high-sensitivity-troponin-t-than-other-biomarkers
#18
Theodore Pipikos, Alkistis Kapelouzou, Diamantis I Tsilimigras, Yannis Fostinis, Marina Pipikou, Athanassios Theodorakos, Antonis N Pavlidis, Christos Kontogiannis, Dennis V Cokkinos, Maria Koutelou
BACKGROUND: Acute myocardial infarction (AMI) is considered a major cause of death and disability. Myocardial perfusion scintigraphy (MPS) as a non-invasive diagnostic imaging procedure and certain biomarkers associated with myocardial ischemia (ISCH), such as ischemia-modified albumin (IMA), neuropeptide Y (NPY), N-terminal pro b-type natriuretic peptide (NT-proBNP), and high-sensitivity troponin T (hsTnT) could probably aid in the detection of myocardial infarction. METHODS: Between December 2011 and June 2012, we prospectively analyzed patients who underwent a MPS study with the clinical question of myocardial ISCH...
January 29, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29371002/the-predictive-value-of-nt-probnp-and-hs-tnt-for-risk-of-death-in-cardiac-surgical-patients
#19
Jon Brynildsen, Liisa Petäjä, Ville Pettilä, Ståle Nygård, Suvi T Vaara, Rita Linko, Marjatta Okkonen, Tor-Arne Hagve, Leena Soininen, Raili Suojaranta-Ylinen, Magnus Nakrem Lyngbakken, Torbjørn Omland, Helge Røsjø
BACKGROUND: European System for Cardiac Operative Risk Evaluation II (EuroSCORE II) is used for risk stratification before cardiac surgery, but whether N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity troponin T (hs-TnT) may add prognostic information to EuroSCORE II is not known. METHODS: Preoperative (n=640) and postoperative (n=629) blood samples were available from cardiac surgical patients with 961-day follow-up (FINNAKI Heart study; cohort #1)...
March 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29340731/sensitive-cardiac-troponins-could-they-be-new-biomarkers-in-pediatric-pulmonary-hypertension-due-to-congenital-heart-disease
#20
Seyma Kayali, Ilker Ertugrul, Tamer Yoldas, Ozkan Kaya, Senem Ozgür, Utku A Orün, Selmin Karademir
To analyze the role of sensitive cardiac troponin I (scTnI) and high-sensitive troponin T (hscTnT) in the determination of myocardial injury caused by volume and pressure load due to pulmonary hypertension (PH) and to investigate if these markers may be useful in the management of PH in childhood. Twenty-eight patients with congenital heart disease (CHD) with left to right shunt and PH, 29 patients with CHD with left to right shunt but without PH, and 18 healthy children, in total 75 individuals, were included in the study...
April 2018: Pediatric Cardiology
keyword
keyword
41060
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"