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https://www.readbyqxmd.com/read/29156332/effective-flocculation-of-microcystis-aeruginosa-with-simultaneous-nutrient-precipitation-from-hydrolyzed-human-urine
#1
Yan-Shan Wang, Zhong-Hua Tong, Long-Fei Wang, Guo-Ping Sheng, Han-Qing Yu
Mechanical harvest of massive harmful algal blooms is an effective measure for bloom mitigation. Yet subsequent processing of the resulting water from algae water separation after the harvesting becomes a new problem since individual algal cells or small algal aggregates are still present in the water. Here, we proposed a novel approach for effectively flocculating the cyanobacteria Microcystis aeruginosa with a removal efficiency of 97% in 6 h using hydrolyzed urine. Nitrogen and phosphorus were simultaneously reclaimed through struvite formation...
November 11, 2017: Chemosphere
https://www.readbyqxmd.com/read/29154708/urethral-diverticulum-and-urolithiasis-in-a-female-guinea-pig-cavia-porcellus
#2
Lily A B Parkinson, Jennifer C Hausmann, Robert J Hardie, Megan A Mickelson, Kurt K Sladky
CASE DESCRIPTION A 5-year-old sexually intact female guinea pig was evaluated because of mild dysuria and a subcutaneous mass located cranioventral to the urogenital openings. CLINICAL FINDINGS Non-contrast-enhanced CT and surgical exploration of the distal aspect of the urethra revealed a urethral diverticulum with an intraluminal urolith. Analysis revealed that the urolith was composed of calcium carbonate and struvite. TREATMENT AND OUTCOME The urolith was surgically removed and ablation of the urethral diverticulum was attempted...
December 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29152298/medullary-nephrocalcinosis-in-idiopathic-hypercalciuria
#3
Abhilash Koratala, Vikrampal Bhatti
Idiopathic hypercalciuria is a metabolic abnormality characterized by excessive calcium excretion in the urine with normal serum calcium levels and is a common risk factor for formation of kidney stones and/or nephrocalcinosis. These patients benefit from a normal-calcium, reduced-animal protein, and low-salt diet, along with a thiazide diuretic.
November 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29152254/calcium-intake-and-the-associations-with-faecal-fat-and-energy-excretion-and-lipid-profile-in-a-free-living-population
#4
Louise Kjølbæk, Janne K Lorenzen, Lesli H Larsen, Arne Astrup
The aim of the present study was to investigate the associations between the habitual Ca intake and faecal fat and energy excretion as well as blood lipid profile in free-living normal-weight and overweight individuals. The participants were enrolled for an 8-d period where data from a 7-d diet registration (days 1-7), a 5-d faeces collection (days 3-7), a 2-d urine collection (days 5-7), and anthropometric measurements and a fasting blood sample (day 8) were collected. Analyses showed that dietary Ca intake (g/10 MJ per d) was positively associated with excretion of faecal fat (P = 0·004) and energy (P = 0·031) when adjusted for BMI, age, sex and intake of Ca-containing supplements...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29151300/the-effect-of-antidiuretic-hormone-on-urine-and-serum-electrolyte-levelsin-children-with-primary-monosymptomatic-nocturnal-enuresis
#5
(no author information available yet)
Background/aim: The data concerning the effects of desmopressin on water/electrolyte disturbances of children with primary monosymptomatic nocturnal enuresis (PMNE) are limited. In the present study we aimed to evaluate the effect and tolerability of desmopressin on blood and urine electrolytes and osmolality in PMNE.Materials and methods: Thirty-five children with PMNE between the ages of 5 and 15 participated in the study. Patients collected urine during the daytime and acknowledged the night time fluid restriction before starting to use the desmopressin tablets...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29145146/evaluation-of-anti-urolithiatic-and-diuretic-activities-of-watermelon-citrullus-lanatus-using-in-vivo-and-in-vitro-experiments
#6
Waqar Ahmed Siddiqui, Muhammad Shahzad, Arham Shabbir, Ali Ahmad
Traditionally, Citrullus lanatus is known to have protective properties in kidney diseases and for having the ability to clear urine. Current study aims to validate the traditional uses of C. lanatus by evaluation of anti-urolithiatic and diuretic activities using in vivo and in vitro experiments. Male Wistar rats were used for in vivo anti-urolithiatic and diuretic activities. Supersaturated solution of calcium and oxalate was used for in vitro crystallization study. Hematoxylin & eosin staining was used for histopathological evaluation of kidney...
November 11, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29140511/two-fatal-cases-involving-cardiovascular-drugs-diltiazem-and-amlodipine
#7
Luca Morini, Matteo Moretti, Francesca Brandolini, Antonio Marco Maria Osculati, Angelo Groppi, Claudia Vignali
A liquid chromatographic tandem mass spectrometric method for the identification and quantification of 18 cardiovascular drugs was developed in order to evaluate two cases of fatal intoxication involving diltiazem and amlodipine respectively. Samples were simply diluted and centrifuged using a three-steps procedure with methanol, acetonitrile and mobile phase. The method proved to be selective and all the validation parameters fulfilled the acceptance criteria. In particular, linearity was studied in the range limits of quantitation (LOQ)-1,000 ng/mL (LOQ ranging from 0...
November 13, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/29135157/-calciuria-as-a-metabolic-marker-for-various-conditions-and-diseases
#8
L V Egshatyan, N G Mokrysheva
The article analyzes the literature on the features of human calcium homeostasis. The authors describe the etiopathogenetic role of calcitropic hormones, the plasma and urine acid-base status, various ions, lifestyle and nutrition and other factors contributing to hypercalciuria due to increased intestinal absorption, bone resorption, impairment of tubular calcium reabsorption, etc. They discuss the role of calciuria as a factor in forming urinary calculi and present their own observations.
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29132983/relative-supersaturation-of-24-hour-urine-and-likelihood-of-kidney-stones
#9
Megan Prochaska, Eric Taylor, Pietro Manuel Ferraro, Gary Curhan
PURPOSE: Relative supersaturations of calcium oxalate, calcium phosphate, and uric acid are used clinically in kidney stone prevention. The magnitudes of association between relative supersaturation and stone risk require further quantification. MATERIALS AND METHODS: We performed a cross-sectional study using 24-hour urine collections from Nurses' Health Study I (NHS I), Nurses' Health Study II (NHS II), and Health Professional Follow-up Study (HPFS) cohorts to quantify the association between calcium oxalate, calcium phosphate, and uric acid relative supersaturations levels and likelihood of stone formation...
November 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29131397/a-double-blind-placebo-controlled-multicenter-prospective-randomized-study-of-beraprost-sodium-treatment-for-cats-with-chronic-kidney-disease
#10
M Takenaka, A Iio, R Sato, T Sakamoto, H Kurumatani
BACKGROUND: Chronic kidney disease (CKD) is a common progressive and irreversible disease in cats. The efficacy and safety of beraprost sodium (BPS) in cats with CKD have not been evaluated. HYPOTHESIS/OBJECTIVES: To evaluate the efficacy and safety of BPS in the treatment of cats with CKD, as compared to placebo. ANIMALS: Seventy-four client-owned cats with naturally occurring CKD. METHODS: Double-blind, placebo-controlled, multicenter, prospective, randomized trial...
November 13, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29130735/evaluation-of-the-pharmacodynamic-effects-of-the-potassium-binder-rdx7675-in-mice
#11
James P Davidson, Andrew J King, Padmapriya Kumaraswamy, Jeremy S Caldwell, Paul Korner, Robert C Blanks, Jeffrey W Jacobs
INTRODUCTION: Hyperkalemia is a common complication in patients with heart failure or chronic kidney disease, particularly those who are taking inhibitors of the renin-angiotensin-aldosterone system. RDX7675, the calcium salt of a reengineered polystyrene sulfonate-based resin, is a potassium binder that is being investigated as a novel treatment for hyperkalemia. This study evaluated the pharmacodynamic effects of RDX7675 in mice, compared to 2 current treatments, sodium polystyrene sulfonate (SPS) and patiromer...
January 1, 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29126251/evidence-for-a-role-of-pdz-domain-containing-proteins-to-mediate-hypophosphatemia-in-calcium-stone-formers
#12
Kristin J Bergsland, Fredric L Coe, Joan H Parks, John R Asplin, Elaine M Worcester
Background: Hypophosphatemia (HYP) is common among calcium stone formers (SFs) and in rare cases is associated with mutations in sodium-phosphate cotransporters or in Na+/H+ exchanger regulatory factor 1 (NHERF1), but the majority of cases are unexplained. We hypothesized that reduced sodium-phosphate cotransporter activity mediated via NHERF1 or a similar PDZ domain-containing protein, causes HYP. If so, other transport activities controlled by NHERF1, such as NHE3 and URAT1, might be reduced in HYP...
November 6, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29119397/specific-features-of-electrolyte-excretion-at-the-early-stages-of-arterial-hypertension-in-shr-rats
#13
M L Blagonravov, E V Medvedeva, A A Bryk, V A Goryachev, M M Azova, E V Velichko
Daytime and nighttime systolic and diastolic BP was recorded in 23-week-old SHR and Wistar rats by telemetric monitoring. Urine concentrations of sodium, potassium, and calcium were determined in SHR rats during of light (07.00-19.00 h) and dark hours (19.00-07.00 h) at the age of 18, 19, 20, 21, 22, and 23 week; 23-week-old Wistar rats were used as the control. At early stages of the experiment, urine sodium concentration was elevated in SHR rats both at daytime and at night. Thereafter, this value declined and by 22-23 week was significantly lower than in normotensive Wistar rats, but only during daytime...
November 9, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29117629/medical-and-dietary-interventions-for-preventing-recurrent-urinary-stones-in-children
#14
REVIEW
Adam Kern, Gwen Grimsby, Helen Mayo, Linda A Baker
BACKGROUND: Nephrolithiasis, or urinary stone disease, in children causes significant morbidity, and is increasing in prevalence in the North American population. Therefore, medical and dietary interventions (MDI) for recurrent urinary stones in children are poised to gain increasing importance in the clinical armamentarium. OBJECTIVES: To assess the effects of medical and dietary interventions (MDI) for the prevention of idiopathic urinary stones in children aged from one to 18 years...
November 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29116604/supplementation-of-pig-diets-in-the-growth-and-termination-phases-with-different-calcium-sources
#15
Ana Lúcia Almeida Santana, Paulo Levi de Oliveira Carvalho, Eliseu Carlos Cristofori, Poliana Caroline da Silva Chambo, Mariana Barbizan, Ricardo Vianna Nunes, Cristine Regina Gregory, Jansller Luiz Genova
The aim of this study was to evaluate the effect of supplementation of pig diets in the growth and termination phases with different calcium sources. In experiment I, 36 whole males were distributed in randomized blocks in six groups, with six replications. A basal diet was formulated to meet the animals' nutritional requirements except for calcium (0.09%), and the sources evaluated (calcitic limestone, monodicalcium phosphate, calcinated bone flour, and oyster flour) replaced the basal diet to provide 0.59% of total calcium...
November 7, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29113983/fgf23-concentration-and-apol1-genotype-are-novel-predictors-of-mortality-in-african-americans-with-type-2-diabetes
#16
Gary C Chan, Jasmin Divers, Gregory B Russell, Carl D Langefeld, Lynne E Wagenknecht, Fang-Chi Hsu, Jianzhao Xu, S Carrie Smith, Nicholette D Palmer, Pamela J Hicks, Donald W Bowden, Thomas C Register, Lijun Ma, J Jeffrey Carr, Barry I Freedman
OBJECTIVE: Cardiovascular and renal complications contribute to higher mortality in patients with diabetes. We assessed novel and conventional predictors of mortality in African American-Diabetes Heart Study participants. RESEARCH DESIGN AND METHODS: Associations between mortality and subclinical atherosclerosis, urine albumin-to-creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), plasma fibroblast growth factor 23 (FGF23) concentration, African ancestry proportion, and apolipoprotein L1 genotypes (APOL1) were assessed in 513 African Americans with type 2 diabetes; analyses were performed using Cox proportional hazards models...
November 7, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29106383/s-sulfocysteine-nmda-receptor-dependentsignaling-underlies-neurodegeneration-in-molybdenum-cofactor-deficiency
#17
Avadh Kumar, Borislav Dejanovic, Florian Hetsch, Marcus Semtner, Debora Fusca, Sita Arjune, Jose Angel Santamaria-Araujo, Aline Winkelmann, Scott Ayton, Ashley I Bush, Peter Kloppenburg, Jochen C Meier, Guenter Schwarz, Abdel Ali Belaidi
Molybdenum cofactor deficiency (MoCD) is an autosomal recessive inborn error of metabolism characterized by neurodegeneration and death in early childhood. The rapid and progressive neurodegeneration in MoCD presents a major clinical challenge and may relate to the poor understanding of the molecular mechanisms involved. Recently, we reported that treating patients with cyclic pyranopterin monophosphate (cPMP) is a successful therapy for a subset of infants with MoCD and prevents irreversible brain damage. Here, we studied S-sulfocysteine (SSC), a structural analog of glutamate that accumulates in the plasma and urine of patients with MoCD, and demonstrated that it acts as an N-methyl D-aspartate receptor (NMDA-R) agonist, leading to calcium influx and downstream cell signaling events and neurotoxicity...
November 6, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29095693/reference-intervals-for-stone-risk-factors-in-24-h-urine-among-healthy-adults-of-the-han-population-in-china
#18
Zanlin Mai, Xiaoxia Li, Zelin Cui, Wenqi Wu, Yongda Liu, Lili Ou, Yueping Liang, Zhijian Zhao, Yang Liu, Xing Mai, Wei Zhu, Tao Zhang, Chao Cai, Houmeng Yang, Guohua Zeng
BACKGROUND: The aim of the study was to establish reference intervals for 24-h urinary stone risk factors in the healthy Chinese Han population. METHODS: From May 2013 to July 2014, we collected and analyzed 24-h urine samples from healthy adult Han population during a cross-sectional study across China. The protocol for analysis of 24-h urine included volume, pH, oxalate, citrate, sodium, potassium, chloride, calcium, phosphorous, creatinine, urate, magnesium, the ion activity products of calcium oxalate (AP(CaOx) indexs) and calcium phosphate (AP(CaP) indexs)...
November 2, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29095605/mimicking-and-inhibiting-urea-hydrolysis-in-nonwater-urinals
#19
Daniella Saetta, Treavor H Boyer
Nonwater urinals are critical in the implementation of building-scale water conservation and urine diversion systems. However, due to the composition of urine and the prevalence of the urease enzyme that hydrolyzes urea, minerals readily precipitate in nonwater urinals and pipes. This leads to clogging, malodor, and possible replacement of nonwater urinals with flush urinals. Accordingly, the goal of this research was to provide an improved understanding of the urea hydrolysis process in nonwater urinals to benefit water conservation and phosphate recovery efforts...
November 2, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29082239/molecular-mechanisms-and-treatment-strategies-in-diabetic-nephropathy-new-avenues-for-calcium-dobesilate-free-radical-scavenger-and-growth-factor-inhibition
#20
REVIEW
Hermann Haller, Linong Ji, Klaus Stahl, Anna Bertram, Jan Menne
Diabetic nephropathy is one of the most important microvascular complications of diabetes mellitus and is responsible for 40-50% of all cases of end stage renal disease. The therapeutic strategies in diabetic nephropathy need to be targeted towards the pathophysiology of the disease. The earlier these therapeutic strategies can bring about positive effects on vascular changes and prevent the vasculature in patients with diabetes from deteriorating, the better the renal function can be preserved. Studies evaluating anti-inflammatory and antioxidative strategies in diabetic nephropathy demonstrate the need and value of these novel treatment avenues...
2017: BioMed Research International
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