Yoshiaki Norimatsu, Tomoyuki Miyamoto, Tadao K Kobayashi, Tomohiro Oda, Takuya Moriya, Kenji Yanoh, Yasuyuki Miyake, Eiji Ohno
This article focuses on the characteristic features of morphology and molecular biology of PTEN, beta-catenin, and p53 immunocytochemistry in normal endometrium (proliferative, secretory, and atrophic) and endometrial glandular and stromal breakdown (EGBD) using thin-layer specimens. During a 6-month period, 120 endometrial samples were collected directly using the Uterobrush and a thin-layer specimen was prepared. Immunocytochemical expression of PTEN, beta-catenin, and p53 were investigated using 30 cases each of proliferative endometrium (PE), secretory endometrium (SE), atrophic endometrium (AE), and EGBD...
April 2008: Diagnostic Cytopathology