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https://www.readbyqxmd.com/read/28743142/infrapatellar-fat-pad-impingement-a-systematic-review
#1
Jason Genin, Mhamad Faour, Prem N Ramkumar, George Yakubek, Anton Khlopas, Morad Chughtai, Michael A Mont, Dominic King
No abstract text is available yet for this article.
July 25, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28742213/derivatization-agents-for-electrochemical-detection-in-amino-acid-peptide-and-protein-separations-the-hidden-electrochemistry
#2
REVIEW
Tania Sierra, Agustin G Crevillen, Alberto Escarpa
In proteomics and clinical analysis, LIF and MS are the most used detectors coupled to separation techniques. MS offers good sensitivity and analyte identification ability but, as counterbalance, it is expensive and it needed background electrolytes compatible with mass spectrometers. LIF detection offers the highest sensitivity but, in general, proteins, peptides and amino acids are not fluorescents so it is necessary the use of fluorescence tags. This fact hindered the potential sensitivity of LIF detection due to the difficulty of labeling analytes at extremely low concentrations...
July 25, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28742134/hemostasis-pad-combined-with-compression-device-after-transradial-coronary-procedures-a-randomized-controlled-trial
#3
Si-Hyuck Kang, Donghoon Han, Sehun Kim, Chang-Hwan Yoon, Jin-Joo Park, Jung-Won Suh, Young-Seok Cho, Tae-Jin Youn, In-Ho Chae
BACKGROUND: Arterial access and hemostasis are important processes during percutaneous coronary procedures. In this study, we tested if the use of chitosan-based pads on top of compression devices could improve hemostasis efficacy compared with compression devices alone after transradial coronary angiography or interventions. METHODS: This study was a single-center open-label randomized controlled trial. Patients who underwent coronary angiography or intervention with the transradial approach were randomly assigned to the study (compression device and a chitosan-based pad) or control (compression devices alone) group in a 2:1 fashion...
2017: PloS One
https://www.readbyqxmd.com/read/28741838/intrauterine-exposure-to-oestradiol-promotes-sex-specific-differential-effects-on-the-prostatic-development-of-neonate-gerbils
#4
Bruno D A Sanches, Juliana S Maldarine, Manoel F Biancardi, Fernanda C A Santos, Maria E Pinto-Fochi, Julia Q Antoniassi, Rejane M Goés, Patrícia S L Vilamaior, Sebastião R Taboga
The effects of intrauterine exposure to 17β-oestradiol (E2) are well studied for the male prostate and there are accumulating evidences that the exposure to high dosages leads to a hypomorphic development. However there is a lack of information about the effects of intrauterine exposure to E2 in the prostate of rodent females, and such research becomes relevant in view of the presence of functional prostate in a proportion of women, and the morphophysiological similarities between the prostate of female rodents and the prostate of women...
July 25, 2017: Cell Biology International
https://www.readbyqxmd.com/read/28740902/urinary-quality-of-life-outcomes-in-men-who-were-treated-with-image-guided-intensity-modulated-radiation-therapy-for-prostate-cancer
#5
Simpa S Salami, Edward Obedian, Shawn Zimberg, Carl A Olsson
PURPOSE: Quality of life (QoL) outcomes play a major role in the treatment selection for prostate cancer (CaP). We evaluated the urinary QoL outcomes in men who were treated with image-guided intensity-modulated radiation therapy (IG-IMRT) for CaP. METHODS AND MATERIALS: We enrolled men who were diagnosed with CaP and underwent IG-IMRT in a large urological group practice into a prospectively maintained database. The typical radiation treatment dosage to prostates and seminal vesicles was 8100 cGy in 45 fractions...
October 2016: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28739087/inhibition-of-lipolysis-by-ilexgenin-a-via-ampk-activation-contributes-to-the-prevention-of-hepatic-insulin-resistance
#6
Lan-Zhu Li, Tong Zhang, Lan Yang, Lijuan Zhang, Lulu Wang, Baolin Liu, Kang Liu
Adipose dysfunction links tightly to hepatic insulin resistance and gluconeogenesis. Ilexgenin A is reported with the ability to regulate lipid profile and protect the liver against high fat diet (HFD) -induced impairment. Here, we propose that ilexgenin A ameliorates hepatic insulin signaling and gluconeogenesis by regulating lipolysis in white adipose tissue (WAT). Pyruvate tolerance test and biochemical analysis coupled with the ex vivo siRNA knockdown and co-culture studies demonstrate that ilexgenin A suppresses inflammation-associated lipolysis in epididymal fat pad via 5'-AMP-activated protein kinase (AMPK) activation, thus inhibits diacylglycerol (DAG) accumulation and protein kinase C ε (PKCε) translocation in liver, leading to the improvement of insulin sensitivity and hepatic glucose production...
July 21, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28738580/true-lab-in-a-syringe-technology-for-bioassays
#7
Lenka Hárendarčíková, Daniel Baron, Andrea Šebestová, Jan Rozsypal, Jan Petr
In our work, we introduced a novel concept of the lab-in-a-syringe tests. We solved the problem of detection in already published LIS tests by putting all the reaction and detection pads directly into the syringe barrel. We also used more layers to make the results visible for users. Two detection layouts: (i) with using rounded pads-based detection, and (ii) with using rectangular detection pads, were studied. As the proof of concept, we studied the determination of Ni(II) using dimethylglyoxime as the reagent and blocking of the interference of Fe(II)...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28737833/the-natural-history-of-oviposition-on-a-ginkgophyte-fruit-from-the-middle-jurassic-of-northeastern-china
#8
Qing-Min Meng, Conrad C Labandeira, Qiao-Ling Ding, Dong Ren
A distinctive pattern of oviposition lesions occurs on a ginkgoalean seed, Yimaia capituliformis, which likely was inflicted by a kalligrammatid lacewing with a long, sword-like, plant piercing ovipositor. This newly recorded oviposition type, DT272, occurs in the 165 million-year-old Jiulongshan Formation, of Middle Jurassic age, in Northeastern China. DT272 consists from three to seven, approximately equally spaced lesions with surrounding callus tissue whose fabricator targeted fleshy outer and inner tissues of a ginkgophyte fruit...
July 24, 2017: Insect Science
https://www.readbyqxmd.com/read/28737072/the-effect-of-metatarsal-padding-on-pain-and-functional-ability-in-metatarsalgia
#9
K Männikkö, J Sahlman
BACKGROUND AND AIMS: Many kinds of insoles and pads are commonly used as a conservative treatment of metatarsalgia. However, earlier studies of insole treatment provide contradictory results, and the natural progression of metatarsalgia is still unknown. The aims of this study were to (1) determine whether simple custom-made metatarsal pad insoles reduce pain and improve functional ability, (2) find out patients' satisfaction with padding treatment, and (3) investigate predisposing factors for metatarsalgia...
March 1, 2017: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/28735949/hip-flexor-muscle-dysfunction-during-walking-at-self-selected-and-fast-speed-in-patients-with-aortoiliac-peripheral-arterial-disease
#10
Takaaki Kakihana, Osamu Ito, Yusuke Sekiguchi, Daisuke Ito, Hitoshi Goto, Daijirou Akamatsu, Yasuharu Matsumoto, Masahiro Kohzuki
OBJECTIVE: Intermittent claudication aggravates physical function and is associated with an increased risk of death in patients with peripheral arterial disease (PAD). Previous studies on kinetic parameters (joint moment and power) of lower limbs in these patients have largely focused on the decline in the ankle plantar flexor moment and power at self-selected (SS) walking speed, which may not be an optimal condition to induce claudication pain. In the present study, we investigated the abnormalities in joint kinetic parameters in patients with PAD at both SS and at fast walking speeds...
August 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28735746/parallel-inhibitory-and-excitatory-trigemino-facial-feedback-circuitry-for-reflexive-vibrissa-movement
#11
Marie-Andrée Bellavance, Jun Takatoh, Jinghao Lu, Maxime Demers, David Kleinfeld, Fan Wang, Martin Deschênes
Animals employ active touch to optimize the acuity of their tactile sensors. Prior experimental results and models lead to the hypothesis that sensory inputs are used in a recurrent manner to tune the position of the sensors. A combination of electrophysiology, intersectional genetic viral labeling and manipulation, and classical tracing allowed us to identify second-order sensorimotor loops that control vibrissa movements by rodents. Facial motoneurons that drive intrinsic muscles to protract the vibrissae receive a short latency inhibitory input, followed by synaptic excitation, from neurons located in the oralis division of the trigeminal sensory complex...
July 13, 2017: Neuron
https://www.readbyqxmd.com/read/28735679/soluble-endoglin-as-a-prognostic-factor-of-the-claudication-distance-improvement-in-patients-with-peripheral-artery-disease-undergoing-supervised-treadmill-training-program
#12
Rafał Januszek, Piotr Mika, Roman Nowobilski, Witold Nowak, Anna Kusienicka, Damian Klóska, Paweł Maga, Rafał Niżankowski
Conservative therapy after complete revascularization is increasing in popularity in patients with peripheral artery disease (PAD). The aim of the present study was to find determinants of the improvement of walking abilities and endothelial function in patients with PAD undergoing supervised treadmill training program (STTP). The presented study enclosed 66 patients in the mean age 65.4 ± 7.7 years with PAD who underwent a 3-month length STTP. We assessed the effect of following factors on the change of the flow-mediated dilatation value (ΔFMD), maximal walking time (ΔMWT), and pain-free walking time (ΔPFWT)...
June 28, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28735546/room-temperature-quantum-ballistic-transport-in-monolithic-ultrascaled-al-ge-al-nanowire-heterostructures
#13
Masiar Sistani, Philipp Staudinger, Johannes Greil, Martin Holzbauer, Hermann Detz, Emmerich Bertagnolli, Alois Lugstein
Conductance quantization at room temperature is a key requirement to utilize ballistic transport for e.g. high performance, low power dissipating transistors operating at the upper limit of ON-state conductance or multi-valued logic gates. So far, studying conductance quantization has been restricted to high mobility materials at ultralow temperatures and requires sophisticated nanostructure formation techniques and precise lithography for contact formation. Utilizing a thermally induced exchange reaction between single-crystalline Ge nanowires (NWs) and Al pads, we achieved monolithic Al-Ge-Al NW heterostructures with ultrasmall Ge segments contacted by self-aligned quasi one-dimensional crystalline Al (c-Al) leads...
July 22, 2017: Nano Letters
https://www.readbyqxmd.com/read/28735205/unconventional-gas-development-facilitates-plant-invasions
#14
Kathryn M Barlow, David A Mortensen, Patrick J Drohan, Kristine M Averill
Vegetation removal and soil disturbance from natural resource development, combined with invasive plant propagule pressure, can increase vulnerability to plant invasions. Unconventional oil and gas development produces surface disturbance by way of well pad, road, and pipeline construction, and increased traffic. Little is known about the resulting impacts on plant community assembly, including the spread of invasive plants. Our work was conducted in Pennsylvania forests that overlay the Marcellus and Utica shale formations to determine if invasive plants have spread to edge habitat created by unconventional gas development and to investigate factors associated with their presence...
July 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28734461/risk-factors-for-mortality-among-individuals-with-peripheral-arterial-disease
#15
Stephen M Amrock, Cherrie Z Abraham, Enjae Jung, Pamela B Morris, Michael D Shapiro
Morbidity and mortality from peripheral arterial disease (PAD) continues to increase. Traditional cardiovascular risk factors are implicated in the development of PAD, yet the extent to which those risk factors correlate with mortality in such patients remains insufficiently assessed. Using data from the 1999 to 2004 National Health and Nutrition Examination Survey, Cox proportional hazards models were used to examine the association of cardiovascular risk factors and all-cause and cardiovascular mortality...
June 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28734257/comparison-of-femoropopliteal-artery-stents-under-axial-and-radial-compression-axial-tension-bending-and-torsion-deformations
#16
Kaspars Maleckis, Paul Deegan, William Poulson, Cole Sievers, Anastasia Desyatova, Jason MacTaggart, Alexey Kamenskiy
High failure rates of Peripheral Arterial Disease (PAD) stenting appear to be associated with the inability of certain stent designs to accommodate severe biomechanical environment of the femoropopliteal artery (FPA) that bends, twists, and axially compresses during limb flexion. Twelve Nitinol stents (Absolute Pro, Supera, Lifestent, Innova, Zilver, Smart Control, Smart Flex, EverFlex, Viabahn, Tigris, Misago, and Complete SE) were quasi-statically tested under bench-top axial and radial compression, axial tension, bending, and torsional deformations...
July 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28733607/two-year-follow-up-of-vascular-events-in-peripheral-arterial-disease-treated-with-antiplatelet-agents-a-prospective-observational-multicenter-cohort-study-season
#17
Yukihito Higashi, Tetsuro Miyata, Hiroshi Shigematsu, Hideki Origasa, Masatoshi Fujita, Hiroshi Matsuo, Hiroaki Naritomi, Hiroaki Matsuda, Masahide Nakajima, Hideto Awano
The present analysis was intended to evaluate the real-world management of peripheral arterial disease (PAD) in Asia, and to explore cardiovascular events in patients with PAD undergoing antiplatelet therapy over 2 years of follow-up. The Surveillance of cardiovascular Events in Antiplatelet-treated arteriosclerosis Obliterans patients in JapaN (SEASON) registry is a prospective observational multicenter study of cardiovascular events in antiplatelet-treated patients with PAD in Japan. The SEASON registry included 11,375 patients who were scheduled to receive treatment for PAD...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733574/metabolomic-characteristics-of-cholesterol-induced-non-obese-nonalcoholic-fatty-liver-disease-in-mice
#18
Lan N Tu, Megan R Showalter, Tomas Cajka, Sili Fan, Viju V Pillai, Oliver Fiehn, Vimal Selvaraj
Nonalcoholic fatty liver disease (NAFLD) in non-obese patients remains a clinical condition with unclear etiology and pathogenesis. Using a metabolomics approach in a mouse model that recapitulates almost all the characteristic features of non-obese NAFLD, we aimed to advance mechanistic understanding of this disorder. Mice fed high fat, high cholesterol, cholate (HFHCC) diet for three weeks consistently developed hepatic pathology similar to NAFLD and nonalcoholic steatohepatitis (NASH) without changes to body weight or fat pad weights...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733413/live-cell-imaging-of-the-schizosaccharomyces-pombe-sexual-life-cycle
#19
Laura Merlini, Aleksandar Vjestica, Omaya Dudin, Felipe Bendezú, Sophie G Martin
The fission yeast Schizosaccharomyces pombe is an invaluable model system for studying the principles that drive sexual differentiation and the meiotic cell division cycle. We describe a simple protocol for microscopic observation of the entire sexual life cycle that can be adapted to focus on specific stages of sexual differentiation. After growth to exponential phase in a nitrogen-rich medium, cell cultures are switched to a nitrogen-deprived medium until the population is enriched for the specific stage of the sexual lifecycle to be studied...
July 21, 2017: Cold Spring Harbor Protocols
https://www.readbyqxmd.com/read/28733249/dna-based-random-key-generation-and-management-for-otp-encryption
#20
Yunpeng Zhang, Xin Liu, Manhui Sun
One-time pad (OTP) is a principle of key generation applied to the stream ciphering method which offers total privacy. The OTP encryption scheme has proved to be unbreakable in theory, but difficult to realize in practical applications. Because OTP encryption specially requires the absolute randomness of the key, its development has suffered from dense constraints. DNA cryptography is a new and promising technology in the field of information security. DNA chromosomes storing capabilities can be used as one-time pad structures with pseudo-random number generation and indexing in order to encrypt the plaintext messages...
July 18, 2017: Bio Systems
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