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https://www.readbyqxmd.com/read/27905478/vascular-disease-ticagrelor-not-superior-to-clopidogrel-for-pad
#1
Irene Fernández-Ruiz
No abstract text is available yet for this article.
December 1, 2016: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/27905026/native-matrix-based-human-lung-alveolar-tissue-model-in-vitro-studies-of-the-reparatory-actions-of-mesenchymal-stem-cells
#2
Ieva Bruzauskaite, Jovile Raudoniute, Jaroslav Denkovskij, Edvardas Bagdonas, Sandra Meidute-Abaraviciene, Vaida Simonyte, Daiva Bironaite, Almantas Siaurys, Eiva Bernotiene, Ruta Aldonyte
Studies of lung diseases in vitro often rely on flat, plastic-based monocultures, due to short lifespan of primary cells, complicated anatomy, lack of explants, etc. We hereby present a native 3D model with cues for repopulating epithelial cells. Abilities of mesenchymal stem cells (MSC) to modulate bacterial lipopolysaccharide (LPS) and cigarette smoke-induced injury to pulmonary epithelium were tested in our model. Post-mortem human lung tissue was sliced, cut and decellularized. Resulting matrix pads were reseeded with pulmonary epithelium (A549 line)...
December 1, 2016: Cytotechnology
https://www.readbyqxmd.com/read/27904596/association-of-adiponectin-with-peripheral-arterial-disease-and-mortality-in-nondiabetic-hemodialysis-patients-long-term-follow-up-data-of-7-years
#3
Yijun Zhou, Jiwei Zhang, Weiming Zhang, Zhaohui Ni
BACKGROUND: The relationships between adiponectin and clinical outcomes in hemodialysis (HD) patients remain highly controversial. Meanwhile, the association between adiponectin and the peripheral artery disease (PAD) has not been well studied in HD patients without diabetic mellitus. MATERIALS AND METHODS: The ankle-brachial index was measured in HD patients. Adiponectin levels in 105 HD patients were measured by Enzyme-Linked Immunosorbant Assay. RESULTS: 105 HD patients were enrolled; 14 (13%) patients had PAD...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27904022/morphology-of-the-lingual-papillae-in-the-eastern-grey-kangaroo
#4
Shoichi Emura
We examined the dorsal lingual surface of an adult eastern grey kangaroo (Macropus gigantues) by scanning electron microscopy. The filiform papillae on the lingual apex and anterior body consisted of a main papilla and secondary papillae. The connective tissue core of the filiform papillae on the lingual apex had several processes. The filiform papillae on the lingual posterior body were thread-like in shape. The connective tissue core of the filiform papillae on the lingual posterior body consisted of many slender processes...
2016: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/27903857/a-hyperpigmented-reticular-rash-in-a-patient-on-peritoneal-dialysis
#5
Andrew M South, Milene K Crispin, Ann L Marqueling, Scott M Sutherland
Chronically ill patients often develop uncommon exam findings. A 16-year-old female with end-stage renal disease secondary to immune complex-mediated glomerulonephritis on peritoneal dialysis (PD) developed a pruritic, hyperpigmented reticular rash on her abdomen, sparing the PD catheter insertion site. The rash appeared approximately 6 weeks after initiating PD. She used a heating pad nightly during PD for dialysis drain pain. Testing for systemic and autoimmune disease was negative. She was referred to dermatology, where the diagnosis of erythema ab igne (EAI), a well-described but less well-known hyperpigmented reticular cutaneous eruption caused by chronic exposure to low levels of infrared heat, was confirmed...
November 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27903754/trajectories-to-seeking-demedicalised-assistance-in-suicide-a-qualitative-in-depth-interview-study
#6
Martijn Hagens, Bregje D Onwuteaka-Philipsen, H Roeline W Pasman
BACKGROUND: In the Netherlands, people can receive (limited) demedicalised assistance in suicide (DAS)-an option less well known than physician-assisted dying (PAD). AIM: This study explores which trajectories people take to seek DAS, through open-coding and inductive analysis of in-depth interviews with 17 people who receive(d) DAS from counsellors facilitated by foundation De Einder. RESULTS: People sought DAS as a result of current suffering or as a result of anticipating possible prospective suffering...
November 30, 2016: Journal of Medical Ethics
https://www.readbyqxmd.com/read/27901319/salt-templating-with-pore-padding-hierarchical-pore-tailoring-towards-functionalised-porous-carbons
#7
K Vasanth Kumar, Srinivas Gadipelli, Kathrin Preuss, Harshit Porwal, Tingting Zhao, Zheng Xiao Guo, Maria-Magdalena Titirici
We propose a new synthetic route towards nanoporous functional carbon materials based on salt templating with pore-padding approach (STPP). STPP relies on the use of a pore-padding agent that undergoes an initial polymerisation/ condensation process prior to the formation of a solid carbon framework. The pore-padding agent allows tailoring hierarchically the pore-size distribution and controlling the amount of heteroatom (nitrogen in this case) functionalities as well as the type of nitrogen (graphitic, pyridinic, oxides of nitrogen) incorporated within the carbon framework in a single-step-process...
November 30, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27901227/evaluation-of-cytotoxicity-and-corrosion-resistance-of-orthodontic-mini-implants
#8
Celha Borges Costa Alves, Márcio Nunes Segurado, Miriam Cristina Leandro Dorta, Fátima Ribeiro Dias, Maurício Guilherme Lenza, Marcos Augusto Lenza
Objective: To evaluate and compare in vitro cytotoxicity and corrosion resistance of mini-implants from three different commercial brands used for orthodontic anchorage. Methods: Six mini-implants (Conexão(tm), Neodent(tm) and SIN(tm)) were separately immersed in artificial saliva (pH 6.76) for 30 and 60 days. The cytotoxicity of the corrosion extracts was assessed in L929 cell cultures using the violet crystal and MTT assays, as well as cell morphology under light microscopy...
September 2016: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/27900294/efficacy-of-autologous-leukocyte-reduced-platelet-rich-plasma-therapy-for-patellar-tendinopathy-in-a-rat-treadmill-model
#9
Mamoru Yoshida, Hiroki Funasaki, Keishi Marumo
BACKGROUND: An autologous platelet-rich plasma (PRP) therapy has currently been applied for the tendinopathy; however, its efficacy and an optimal platelets concentration in PRP were uncertain. We analyzed them in an animal model prepared using a repetitive running exercise. METHODS: We made the tendinopathy rat model of patellar tendon using a rodent treadmill machine. Rats with tendinopathy were injected with leukocyte-reduced PRP at the platelets concentration of 1...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27899247/association-of-plasma-fetuin-a-levels-with-peripheral-arterial-disease-and-lower-extremity-arterial-calcification-in-subjects-with-type-2-diabetes-mellitus
#10
Ioanna Eleftheriadou, Pinelopi Grigoropoulou, Alexander Kokkinos, Iordanis Mourouzis, Despoina Perrea, Nicholas Katsilambros, Petros P Sfikakis, Nikolaos Tentolouris
AIMS: Fetuin-A is a hepatic glycoprotein that is involved in insulin resistance and atherosclerosis. Herein we examined the association of plasma fetuin-A levels with peripheral arterial disease (PAD) in patients with type 2 diabetes mellitus (T2DM). MATERIAL AND METHODS: A total of 71 patients with T2DM and 57 non-diabetic individuals were recruited. Diagnosis of PAD was based on the absence of triphasic waveform at pedal arteries, while ankle-brachial index (ABI) was calculated...
November 12, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27899017/public-access-defibrillation-and-outcomes-after-pediatric-out-of-hospital-cardiac-arrest
#11
Tatsuma Fukuda, Naoko Ohashi-Fukuda, Hiroaki Kobayashi, Masataka Gunshin, Toshiki Sera, Yutaka Kondo, Naoki Yahagi
BACKGROUND: Use of automated external defibrillators (AEDs) has been recommended for pediatric out-of-hospital cardiac arrest (OHCA). However, there are no conclusive studies that elucidated the effectiveness of public-access defibrillation (PAD) in children. METHODS: This was a nationwide, population-based, propensity score-matched study of pediatric OHCA in Japan from 2011 to 2012, based on data from the All-Japan Utstein Registry. We included pediatric OHCA patients (aged 1-17 years) who received bystander cardiopulmonary resuscitation...
November 26, 2016: Resuscitation
https://www.readbyqxmd.com/read/27898734/diagnostic-accuracy-study-of-an-oscillometric-ankle-brachial-index-in-peripheral-arterial-disease-the-influence-of-oscillometric-errors-and-calcified-legs
#12
Ángel Herráiz-Adillo, Vicente Martínez-Vizcaíno, Iván Cavero-Redondo, Celia Álvarez-Bueno, Miriam Garrido-Miguel, Blanca Notario-Pacheco
BACKGROUND: Peripheral arterial disease (PAD) is an indicator of widespread atherosclerosis. However, most individuals with PAD, in spite of being at high cardiovascular risk, are asymptomatic. This fact, together with the limitations of the Doppler ankle-brachial index (ABI), contributes to PAD underdiagnose. The aim of this study was to compare oscillometric ABI and Doppler ABI to diagnose peripheral arterial disease, and also to examine the influence of oscillometric errors and calcified legs on the PAD diagnoses...
2016: PloS One
https://www.readbyqxmd.com/read/27895702/ameliorating-effect-of-erxian-decoction-combined-with-fructus-schisandrae-chinensis-wu-wei-zi-on-menopausal-sweating-and-serum-hormone-profiles-in-a-rat-model
#13
Shi Wei Wang, Fei Hua Wu, Yan Bo Zhang, Liang Zhang, Jing Su, Hei Kei Wong, Ai Hua Liu, Ho Pan Cheung, Tzi Bun Ng, Yao Tong, Stephen Cho Wing Sze
BACKGROUND: Modified Erxian decoction (MEXD), i.e., Erxian decoction (EXD) with Fructus Schisandrae chinensis (Wu Wei Zi) added, has been used to alleviate menopausal symptoms. This study aimed to investigate the effects of MEXD on menopausal sweating and serum hormone levels in a rat model of menopause after oral administration of MEXD. METHODS: Quality control of MEXD was conducted by employing a reversed-phase high performance liquid chromatography column. The three treatment groups received oral administration of MEXD in 0...
2016: Chinese Medicine
https://www.readbyqxmd.com/read/27894915/postoperative-temporal-hollowing-is-there-a-surgical-approach-that-prevents-this-complication-a-systematic-review-and-anatomic-illustration
#14
REVIEW
Elbert E Vaca, Chad A Purnell, Arun K Gosain, Mohammed S Alghoul
BACKGROUND: Temporal hollowing is a common complication following surgical dissection in the temporal region. Our objectives were to: (1) review and clarify the temporal soft tissue relationships - supplemented by cadaveric dissection - to better understand surgical approach variations and elucidate potential etiologies of postoperative hollowing; (2) identify if there is any evidence to support a surgical approach that prevents hollowing through a systematic review. METHODS: Cadaveric dissection was performed on six hemi-heads...
November 5, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27894602/evolution-and-degree-of-control-of-cardiovascular-risk-factors-after-5-years-of-follow-up-and-their-relationship-with-the-incidence-of-peripheral-arterial-disease-artper-cohort
#15
Rosa Forés, María Teresa Alzamora, Guillem Pera, Marta Valverde, Maria Angla, José Miguel Baena-Díez, Xavier Mundet-Tuduri
BACKGROUND AND OBJECTIVE: Although cardiovascular risk factors (CVRF) are well known, their degree of control is not optimal. The aim of this study is to assess the evolution and control of CVRFs after 5 years of monitoring a population-based cohort and their association with the incidence of peripheral arterial disease (PAD). MATERIAL AND METHOD: Prospective cohort study recruited between 2006-2008. Second phase between 2011-2012. An ankle brachial index was determined for all participants in both phases...
November 25, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27894254/divergent-selection-induced-obesity-alters-the-composition-and-functional-pathways-of-chicken-gut-microbiota
#16
Jinmei Ding, Lele Zhao, Lifeng Wang, Wenjing Zhao, Zhengxiao Zhai, Li Leng, Yuxiang Wang, Chuan He, Yan Zhang, Heping Zhang, Hui Li, He Meng
BACKGROUND: The gastrointestinal tract is populated by a complex and vast microbial network, with a composition that reflects the relationships of the symbiosis, co-metabolism, and co-evolution of these microorganisms with their host. The mechanism that underlies such interactions between the genetics of the host and gut microbiota remains elusive. RESULTS: To understand how genetic variation of the host shapes the gut microbiota and interacts with it to affect the metabolic phenotype of the host, we compared the abundance of microbial taxa and their functional performance between two lines of chickens (fat and lean) that had undergone long-term divergent selection for abdominal fat pad weight, which resulted in a 4...
November 28, 2016: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/27893636/facial-contouring-by-targeted-restoration-of-facial-fat-compartment-volume-the-mid-face
#17
Wenjin Wang, Yun Xie, Ru-Lin Huang, Jia Zhou, Herrler Tanja, Peijuan Zhao, Chen Cheng, Sizheng Zhou, Lee L Q Pu, Qingfeng Li
BACKGROUND: Recent anatomical findings have suggested that facial fat distribution is complex and changes with age. Here, we developed a grafting technique based on the physiological distribution and volume changes of facial fat compartments to achieve a youthful and natural-looking face. METHODS: Forty cadaveric hemifaces were used for the dissection of fat compartments and neurovascular structures in the mid-face area. Seventy-eight patients were treated for cheek atrophy using our targeted restoration of mid-face fat compartment volume...
November 21, 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27892883/predicting-long-term-prognosis-in-stable-peripheral-artery-disease-with-baseline-functional-capacity-estimated-by-the-duke-activity-status-index
#18
Vichai Senthong, Yuping Wu, Stanley L Hazen, W H Wilson Tang
BACKGROUND: The ability of a simple self-assessment tool for estimated functional capacity to predict long-term prognosis in patients with established peripheral artery disease (PAD) is unknown. We investigate whether subjective measurement of functional capacity estimated by using the Duke Activity Status Index (DASI) questionnaire predicts long-term prognosis in patients with established PAD. METHODS: We administered the DASI questionnaire to 771 stable patients with established PAD who underwent elective diagnostic coronary angiography with 5-year follow-up all-cause mortality...
October 20, 2016: American Heart Journal
https://www.readbyqxmd.com/read/27891487/a-rare-case-of-pyogenic-granuloma-with-a-natal-tooth
#19
Nidhi Agarwal, Dipanshu Kumar, Alaka Vaish, Ashish Anand
Natal teeth are teeth present in the oral cavity at the time of birth. It is extremely rare to find natal teeth in association with pathological conditions of the oral cavity. Pyogenic granuloma is a type of inflammatory hyperplasia that appears as an over exuberant connective tissue response to a stimulus or injury, in the present case the injurious agent is the natal tooth. The parents of the eight day old male infant brought the child with a natal tooth associated with a soft tissue lesion growing from the gum pad...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891180/the-effect-of-foot-orthoses-with-forefoot-cushioning-or-metatarsal-pad-on-forefoot-peak-plantar-pressure-in-running
#20
Michaela Hähni, Anja Hirschmüller, Heiner Baur
BACKGROUND: Foot orthoses are frequently used in sports for the treatment of overuse complaints with sufficient evidence available for certain foot-related overuse pathologies like plantar fasciitis, rheumatoid arthritis and foot pain (e.g., metatarsalgia). One important aim is to reduce plantar pressure under prominent areas like metatarsal heads. For the forefoot region, mainly two common strategies exist: metatarsal pad (MP) and forefoot cushioning (FC). The aim of this study was to evaluate which of these orthosis concepts is superior in reducing plantar pressure in the forefoot during running...
2016: Journal of Foot and Ankle Research
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