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placent previa

Dilek Uysal, Hakan Cokmez, Cetin Aydin, Tolga Ciftpinar
Postpartum haemorrhage is the most important cause of maternal morbidity and mortality, especially when all conservative measures, including syntometrine oxytocin and Bakri balloons have failed to accomplish haemostasis and expeditious surgical procedures, such as uterine artery ligation and emergency peripartum hysterectomy (EPH) are required. This retrospective study analysed 31 cases of EPH performed between January 2007 and January 2016 in the Department of Gynecology and Obstetrics of Izmir Ataturk Teaching and Research Hospital...
March 2018: JPMA. the Journal of the Pakistan Medical Association
Giuseppe Cali, Francesco Forlani, Francesca Foti, Gabriella Minneci, Lamberto Manzoli, Maria Elena Flacco, Danilo Buca, Marco Liberati, Giovanni Scambia, Francesco D'Antonio
OBJECTIVES: To ascertain the diagnostic accuracy of ultrasound in detecting AIP during the first trimester (11-14 weeks of gestation) of pregnancy in women at risk of these conditions. METHODS: Retrospective analysis on prospectively collected data on women at risk for AIP based upon the presence of at least one prior CS and/or uterine surgery and placenta previa who had an ultrasound assessment for AIP since the 11-14 weeks scan. The ultrasound signs explored in the present study were: loss of clear zone, placental lacunae, bladder wall interruption, uterovescical hypervascularity...
March 13, 2018: Ultrasound in Obstetrics & Gynecology
Eun Jung Jung, Hwa Jin Cho, Jung Mi Byun, Dae Hoon Jeong, Kyung Bok Lee, Moon Su Sung, Ki Tae Kim, Young Nam Kim
INTRODUCTION: Placenta previa is a condition in which the placenta implants in the poorly vascularized lower uterine segment, which may result in inadequate uteroplacental perfusion, in turn, adversely affect the neonatal outcome. Abnormal placentation may also lead to severe postpartum hemorrhage as placenta separation proceeds. We aimed to evaluate the differences in placental histopathology and perinatal outcomes in pregnancies complicated with placenta previa and controls. METHOD: We undertook a retrospective case-control study of 93 pregnancies with placenta previa and 81 controls between 2011 and 2017...
March 2018: Placenta
Christina M Duzyj, Irina A Buhimschi, Christine A Laky, Genevieve Cozzini, Guomao Zhao, Mark Wehrum, Catalin S Buhimschi
OBJECTIVE: Placenta accreta is clinically associated with maternal uterine scar. Our objective was to investigate the biochemical contribution of maternal scarring to hyperinvasive trophoblast. We hypothesized that trophoblast over-invasion in placenta accreta is associated with aberrant invasion-site signaling of growth and angiogenic factors known to be involved in wound healing and promotion of cell invasion through the epithelial to mesenchymal cellular program. DESIGN: Cross-sectional series...
February 22, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
Sonia DaSilva-Arnold, Stacy Zamudio, Abdulla Al-Khan, Jesus Alvarez-Perez, Ciaran Mannion, Christopher Koenig, Davlyn Luke, Anisha Perez, Margaret Petroff, Manuel Alvarez, Nicholas P Illsley
Differentiation of first trimester human placental cytotrophoblast from an anchorage-dependent epithelial phenotype into the mesenchymal-like invasive extravillous trophoblast is crucial in the development of the maternal-fetal interface. We showed previously that differentiation of first trimester cytotrophoblast to extravillous trophoblast involves an epithelial-mesenchymal transition (EMT). Here we compare the epithelial-mesenchymal characteristics of cytotrophoblast (CTB) and extravillous trophoblast (EVT) derived from normal third trimester placenta or placenta previa versus abnormally invasive placenta (AIP)...
February 9, 2018: Biology of Reproduction
Michiko Yamashita, Keiichi Kumasawa, Hitomi Nakamura, Tadashi Kimura
INTRODUCTION: Placenta previa is an abnormality in which the placenta covers the internal uterine os, and it can cause serious morbidity and mortality in both mother and fetus due to catastrophic hemorrhage. Some pregnant women recover from placenta previa due to a phenomenon called "migration." However, the mechanism of "migration" of the placenta has not been elucidated. METHODS: Human placentas were collected from patients with placenta previa and those with no abnormal placentation (control)...
January 30, 2018: Biochemical and Biophysical Research Communications
Jennifer K Durst, Methodius G Tuuli, Lorene A Temming, Owen Hamilton, Jeffrey M Dicke
OBJECTIVES: To identify the incidence and resolution rates of a low-lying placenta or placenta previa and to assess the optimal time to perform follow-up ultrasonography (US) to assess for resolution. METHODS: We conducted a retrospective cohort study of women with a diagnosis of a low-lying placenta or placenta previa at routine anatomic screening. Follow-up US examinations were reviewed to estimate the proportion of women who had resolution. A Kaplan-Meier survival curve was generated to estimate the median time to resolution...
February 5, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Kazuki Saito, Maki Fukami, Mami Miyado, Ichiro Ono, Keijiro Sumori
Case: A 39-year-old woman presented with a genital hemorrhage at 5 weeks of gestation after an artificial cycle double frozen-thawed embryo transfer. She was diagnosed with a cervical heterotopic pregnancy. Although hormone supplementation was discontinued to terminate the pregnancy at 5 weeks of gestation, the intrauterine and cervical gestational sacs continued to develop. Outcome: The cervical gestational sac was surgically removed and the intrauterine pregnancy continued uneventfully, except for vasa previa...
January 2018: Reproductive Medicine and Biology
Oonagh E Keag, Jane E Norman, Sarah J Stock
BACKGROUND: Cesarean birth rates continue to rise worldwide with recent (2016) reported rates of 24.5% in Western Europe, 32% in North America, and 41% in South America. The objective of this systematic review is to describe the long-term risks and benefits of cesarean delivery for mother, baby, and subsequent pregnancies. The primary maternal outcome was pelvic floor dysfunction, the primary baby outcome was asthma, and the primary subsequent pregnancy outcome was perinatal death. METHODS AND FINDINGS: Medline, Embase, Cochrane, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were systematically searched for published studies in human subjects (last search 25 May 2017), supplemented by manual searches...
January 2018: PLoS Medicine
Yaakov Melcer, Eric Jauniaux, Shlomit Maymon, Anna Tsviban, Marina Pekar-Zlotin, Moshe Betser, Ron Maymon
BACKGROUND: Placenta accreta spectrum (PAS) and vasa previa (VP) are congenital disorders of placentation associated with high morbidity and mortality for both mothers and newborns when undiagnosed before delivery. Prenatal diagnosis of these conditions is essential to allow multidisciplinary management and thus improve perinatal outcomes. OBJECTIVES: To compare perinatal outcome in women with PAS or VP before and after implementation of targeted scanning protocols...
January 15, 2018: American Journal of Obstetrics and Gynecology
Tingting Sha, Xunqiang Yin, Wenwei Cheng, Isaac Yaw Massey
OBJECTIVE: To provide an updated comparison of pregnancy-related complications and adverse perinatal outcomes of pregnancies conceived after frozen embryo transfer (FET) versus fresh embryo transfer (fresh ET). DESIGN: Meta-analysis. SETTING: University. PATIENT(S): Pregnancies resulting from FET versus fresh ET. INTERVENTIONS(S): Pubmed, Embase, Cochrane Library, Google Scholar, and Chinese databases, including the China National Knowledge Infrastructure Database, Wanfang, and Chinese Scientific Journals Full-Text Database were searched by two independent reviewers from January 1980 to September 2017...
January 11, 2018: Fertility and Sterility
Fatimat M Akinlusi, Kabiru A Rabiu, Idayat A Durojaiye, Adeniyi A Adewunmi, Tawaqualit A Ottun, Yusuf A Oshodi
BACKGROUND: Caesarean delivery carries a risk of major intra-operative blood loss and its performance is often delayed by non-availability of blood and blood products. Unnecessary cross-matching and reservation of blood lead to apparent scarcity in centres with limited supply. This study set out to identify the risk factors for blood transfusion in women who underwent caesarean delivery at a tertiary obstetric unit with a view to ensuring efficient blood utilization. METHODS: A prospective cohort analysis of 906 women who had caesarean deliveries at the Lagos State University Teaching Hospital, Nigeria between January and December, 2011...
January 10, 2018: BMC Pregnancy and Childbirth
Yoshihisa Ono, Yoshihiko Murayama, Sumiko Era, Shigetaka Matsunaga, Tomonori Nagai, Hisato Osada, Yasushi Takai, Kazunori Baba, Satoru Takeda, Hiroyuki Seki
AIMS: We investigated whether common iliac artery balloon occlusion (CIABO) was effective for decreasing blood loss during cesarean hysterectomy (CH) in patients with placenta previa with accreta and was safe for mothers and fetuses. METHODS: Of the 67 patients who underwent CH for placenta previa with accreta at our facility from 1985 to 2014, 57 patients were eligible for the study. The amount of intraoperative bleeding during CH was compared between three groups: surgery without blood flow occlusion (13 patients), internal iliac artery ligation (15 patients) and CIABO (29 patients)...
January 3, 2018: Journal of Obstetrics and Gynaecology Research
R Maymon, Y Melcer, M Pekar-Zlotin, O Shaked, H Cuckle, J Tovbin
PURPOSE: To construct a calculator for 'bedside' estimation of morbidly adherent placenta (MAP) risk based on ultrasound (US) findings. MATERIALS AND METHODS: This retrospective study included all pregnant women with at least one previous cesarean delivery attending in our US unit between December 2013 and January 2017. The examination was based on a scoring system which determines the probability for MAP. RESULTS: The study population included 471 pregnant women, and 41 of whom (8...
December 29, 2017: Archives of Gynecology and Obstetrics
Innie Chen, Shifana Lalani, Ri-Hua Xie, Minxue Shen, Sukhbir S Singh, Shi-Wu Wen
OBJECTIVE: To examine the association between surgically diagnosed endometriosis and pregnancy outcomes in subsequent pregnancies. DESIGN: Retrospective cohort study of women who delivered a singleton live birth from 2003 to 2013 in Ottawa, Ontario, Canada. SETTING: Tertiary level academic center. PATIENT(S): Pregnant women with surgically diagnosed endometriosis were identified using International Classification of Diseases-10 codes from previous hospital admissions and were compared with pregnant women with no prior admission for endometriosis for the occurrences of adverse pregnancy outcomes...
January 2018: Fertility and Sterility
Corinne Hubinont, Mina Mhallem, Pamela Baldin, Frederic Debieve, Pierre Bernard, Eric Jauniaux
OBJECTIVE: To review a single-center case series of placenta percreta and to evaluate risk factors and the impact of surgical techniques used in previous cesarean delivery. METHODS: The present retrospective cohort study included pregnancies with placenta percreta managed between January 1, 2002, and March 31, 2017, at Saint Luc University Hospital, Brussels, Belgium. The data reviewed included demographics, outcomes, inter-pregnancy interval, and surgical techniques used for uterine closure in previous cesarean delivery...
March 2018: International Journal of Gynaecology and Obstetrics
Jaimin Shah, Eduardo Matta, Fernando Acosta, Natalia Golardi, Cristina Wallace-Huff
Background: The detection of a morbidly adherent placenta (MAP) in the first trimester is rare. Risk factors such as multiparity, advanced maternal age, prior cesarean delivery, prior myomectomy, placenta previa, or previous uterine evacuation place patients at a higher risk for having abnormal placental implantation. If these patients have a first trimester missed abortion and fail medical management, it is important that providers have a heightened suspicion for a MAP. Case: A 24-year-old G4P3003 with 3 prior cesarean deliveries underwent multiple rounds of failed medical management for a missed abortion...
2017: Case Reports in Obstetrics and Gynecology
Haitham Baghlaf, Andrea R Spence, Nicholas Czuzoj-Shulman, Haim Arie Abenhaim
PURPOSE: The purpose of this study is to examine the association between maternal asthma and pregnancy, delivery and neonatal outcomes. MATERIALS AND METHODS: We carried out a retrospective cohort study using the Health Care Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) database from 2003 to 2011. Among women who delivered during this time period, we compared pregnancy, delivery, and neonatal outcomes in asthmatics versus non-asthmatics. Multivariate logistic regression was used to estimate adjusted odds ratios and 95% confidence intervals...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
Kei Miyakoshi, Toshimitsu Otani, Eiji Kondoh, Shintaro Makino, Mamoru Tanaka, Satoru Takeda
OBJECTIVE: To investigate maternal outcomes after leaving the placenta in situ for placenta accreta spectrum (PAS) disorders in patients with placenta previa on a cesarean delivery scar. METHODS: The present retrospective study reviewed medical records from women with placenta previa on a cesarean scar underwent perinatal care at secondary- or tertiary-level perinatal centers in Japan between January 1, 2010, and December 31, 2014. Perinatal management was conducted based on each leading obstetrician's discretion...
November 21, 2017: International Journal of Gynaecology and Obstetrics
Zhongyuan Qiu, Jifen Hu, Jianbo Wu, Lihong Chen
BACKGROUND: To evaluate the clinical efficacy of prophylactic temporary balloon occlusion of the abdominal aorta in patients with placenta previa accretism during cesarean section. METHODS: Twenty-three consecutive patients, prenatally confirmed with placenta previa accretism were retrospectively analyzed in our center from August 2012 to October 2014. All 23 subjects underwent cesarean section with prophylactic balloon occlusion of the abdominal aorta. RESULTS: All of the 23 subjects experienced singleton pregnancies leading to the birth of live infants...
November 2017: Medicine (Baltimore)
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