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Anaplasmosis

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https://www.readbyqxmd.com/read/29686681/-anaplasma-phagocytophilum-related-defects-in-cd8-nkt-and-nk-lymphocyte-cytotoxicity
#1
Diana G Scorpio, Kyoung-Seong Choi, J Stephen Dumler
Human granulocytic anaplasmosis, caused by the tick-transmitted Anaplasma phagocytophilum , is not controlled by innate immunity, and induces a proinflammatory disease state with innate immune cell activation. In A. phagocytophilum murine infection models, hepatic injury occurs with production of IFNγ thought to be derived from NK, NKT cells, and CD8 T lymphocytes. Specific A. phagocytophilum ligands that drive inflammation and disease are not known, but suggest a clinical and pathophysiologic basis strikingly like macrophage activation syndrome (MAS) and hemophagocytic syndrome (HPS)...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29653174/molecular-detection-of-anaplasma-phagocytophilum-like-anaplasma-spp-and-pathogenic-a-phagocytophilum-in-cattle-from-south-korea
#2
Min-Goo Seo, In-Ohk Ouh, Oh-Deog Kwon, Dongmi Kwak
Anaplasma phagocytophilum is the causative agent of human granulocytic anaplasmosis and tick-borne fever in domestic ruminants. Differential diagnosis of zoonotic and pathogenic tick-borne diseases like granulocytic anaplasmosis is important for the efficient implementation of control programs. Thus, the differentiation of pathogenic A. phagocytophilum from non-pathogenic A. phagocytophilum-like (APL) Anaplasma spp. is essential. Recent molecular analyses of APL revealed its distinct phylogenetic position from A...
April 10, 2018: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29650038/a-lifelong-study-of-a-pack-rhodesian-ridgeback-dogs-reveals-subclinical-and-clinical-tick-borne-anaplasma-phagocytophilum-infections-with-possible-reinfection-or-persistence
#3
Emil Hovius, Arnout de Bruin, Leo Schouls, Joppe Hovius, Niels Dekker, Hein Sprong
BACKGROUND: Various tick-borne infections often occur without specific clinical signs and are therefore notoriously hard to diagnose separately in veterinary practice. Longitudinal studies over multiple tick seasons performing clinical, serological and molecular investigations in parallel, may elucidate the relationship between infection and disease. In this regard, six related Rhodesian Ridgeback dogs living as a pack became subject of lifetime studies due to ongoing tick infestations and recurring clinical problems...
April 12, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29626656/equine-granulocytic-anaplasmosis-28-years-later
#4
REVIEW
Sehrish Saleem, Muhammad Ijaz, Shahid Hussain Farooqi, Awais Ghaffar, Ahmad Ali, Kashif Iqbal, Khalid Mehmood, Hui Zhang
Equine granulocytic anaplasmosis (EGA) is an important tick borne disease of equines that is caused by Anaplasma phagocytophilum (A. phagocytophilum). The etiological agent has veterinary as well as public health importance because of its zoonotic nature. A. phagocytophilum causes an acute illness in equines with loss of appetite, lethargy, hemorrhages and lameness. Clinically, EGA is diagnosed upon examination of morulae within neutrophils especially granulocytes in the blood. The best diagnostic tool for the detection of EGA is Polymerase chain reaction (PCR)...
April 4, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29584589/molecular-characterization-and-phylogenetic-analysis-of-anaplasma-spp-and-ehrlichia-spp-isolated-from-various-ticks-in-southeastern-and-northwestern-regions-of-iran
#5
Ahmad Jafar Bekloo, Maryam Roya Ramzgouyan, Sadegh Shirian, Faezeh Faghihi, Hassan Bakhshi, Fatemeh Naseri, Mehdi Sedaghat, Zakkyeh Telmadarraiy
INTRODUCTION: Anaplasma/Ehrlichia species are tick-transmitted pathogens that cause infections in humans and numerous domestic and wild animal species. There is no information available on the molecular characteristics and phylogenetic position of Anaplasma/Ehrlichia spp. isolated from tick species from different geographic locations in Iran. The aim of this study was to determine the prevalence, molecular characteristics, and phylogenetic relationship of both Anaplasma spp. and Ehrlichia spp...
March 20, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29581163/human-granulocytic-anaplasmosis-acquired-from-a-blacklegged-tick-in-ontario
#6
Stefan Edginton, T Hugh Guan, Gerald Evans, Siddhartha Srivastava
No abstract text is available yet for this article.
March 26, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29566306/bovine-anaplasmosis-and-tick-borne-pathogens-in-cattle-of-the-galapagos-islands
#7
G V Gioia, R L Vinueza, M Marsot, E Devillers, M Cruz, E Petit, H J Boulouis, S Moutailler, F Monroy, M A Coello, M Gondard, L Bournez, N Haddad, G Zanella
A cross-sectional study was conducted to determine the species of Anaplasma spp. and estimate its prevalence in cattle of the three main cattle-producing Galapagos Islands (Santa Cruz, San Cristóbal and Isabela) using indirect PCR assays, genetic sequencing and ELISA. Ticks were also collected from cattle and scanned for 47 tick-borne pathogens in a 48 × 48 real-time PCR chip. A mixed effects logistic regression was performed to identify potential risk factors explaining Anaplasma infection in cattle. A...
March 22, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29559137/haemoparasitic-agents-associated-with-ovine-babesiosis-a-possible-negative-interaction-between-babesia-ovis-and-theileria-ovis
#8
Ferda Sevinc, Mo Zhou, Shinuo Cao, Onur Ceylan, Mehmet Fatih Aydin, Mutlu Sevinc, Xuenan Xuan
Babesiosis, theileriosis, and anaplasmosis are the most common tick-borne diseases in sheep. The majority of anaplasmosis and theileriosis are subclinical; however, babesiosis causes severe infections in small ruminants. Although there are many reports of co-infections with the agents of these diseases, their clinical severity compared with either of the infections alone is unknown. Within the host, interactions between co-infecting species may cause variations in clinical presentation and response to therapy...
March 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29554975/first-detection-of-borrelia-miyamotoi-in-ixodes-ricinus-ticks-from-northern-italy
#9
Silvia Ravagnan, Laura Tomassone, Fabrizio Montarsi, Aleksandra Iwona Krawczyk, Eleonora Mastrorilli, Hein Sprong, Adelaide Milani, Luca Rossi, Gioia Capelli
BACKGROUND: Borrelia miyamotoi is a spirochete transmitted by several ixodid tick species. It causes a relapsing fever in humans and is currently considered as an emerging pathogen. In Europe, B. miyamotoi seems to occur at low prevalence in Ixodes ricinus ticks but has a wide distribution. Here we report the first detection of B. miyamotoi in Ixodes ricinus ticks collected in two independent studies conducted in 2016 in the north-eastern and north-western Alps, Italy. RESULTS: Three out of 405 nymphs (0...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29530058/molecular-detection-of-anaplasma-bovis-in-holstein-cattle-in-the-republic-of-korea
#10
Jinho Park, Du-Gyeong Han, Ji-Hyoung Ryu, Jeong-Byoung Chae, Joon-Seok Chae, Do-Hyeon Yu, Bae-Keun Park, Hyeon-Cheol Kim, Kyoung-Seong Choi
Anaplasmosis is a tick-borne infectious disease that affects both human and animal health. This study was performed to characterize and investigate the prevalence of infection with Anaplasma bovis in Holstein cattle originating from two regions in the Republic of Korea (ROK). Blood samples (n = 151; 80 from Namwon and 71 from Jeju Island) were analyzed by polymerase chain reaction, and the prevalence of A. bovis infection was compared before and after grazing. In Namwon, A. bovis infection was not detected, while in the Jeju Island, A...
March 12, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29510496/detection-and-characterisation-of-anaplasma-marginale-and-a-centrale-in-south-africa
#11
REVIEW
Paidashe Hove, Zamantungwa T H Khumalo, Mamohale E Chaisi, Marinda C Oosthuizen, Kelly A Brayton, Nicola E Collins
Bovine anaplasmosis is endemic in South Africa and it has a negative economic impact on cattle farming. An improved understanding of Anaplasma marginale and Anaplasma marginale variety centrale (A. centrale) transmission, together with improved tools for pathogen detection and characterisation, are required to inform best management practices. Direct detection methods currently in use for A. marginale and A. centrale in South Africa are light microscopic examination of tissue and organ smears, conventional, nested, and quantitative real-time polymerase chain reaction (qPCR) assays, and a reverse line blot hybridisation assay...
March 3, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29503011/tick-borne-illness-anaplasmosis
#12
REVIEW
Robin B McFee
No abstract text is available yet for this article.
March 1, 2018: Disease-a-month: DM
https://www.readbyqxmd.com/read/29500125/non-traumatic-splenic-rupture-in-a-patient-with-human-granulocytic-anaplasmosis-and-focused-review-of-the-literature
#13
Rafiullah Khan, Asad Ali
We report a rare case of a 53-year-old man with no significant past medical history who reported multiple tick bites within a 2-month period. The patient reported not "feeling well" for the 2 ½ weeks. He complained of generalized body aches, pains, and chills. He did not report nausea, vomiting, or yellowish discoloration of the eyes or skin. He presented to the emergency room with syncope preceded by severe abdominal pain. Upon presentation, he was pale and hypotensive. He had not experienced any trauma...
February 22, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29483058/occurrence-of-tick-borne-haemoparasites-in-cattle-in-the-mungwi-district-northern-province-zambia
#14
Stephen Tembo, Nicola E Collins, Kgomotso P Sibeko-Matjila, Milana Troskie, Ilse Vorster, Charles Byaruhanga, Marinda C Oosthuizen
Little is known about the occurrence of haemoparasites in cattle in communal grazing areas of Mungwi District of Northern Province, Zambia. Clinical signs and post mortem lesions are pathognomonic of mixed tick-borne infections especially babesiosis, anaplasmosis and East Coast fever. The main objective of this study was to screen selected communal herds of cattle for tick-borne haemoparasites, and identify the tick vectors associated with the high cattle mortalities due to suspected tick-borne diseases in the local breeds of cattle grazing along the banks of the Chambeshi River in Mungwi District, Northern Province, Zambia...
February 16, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29479157/exploring-knowledge-and-management-practices-on-ticks-and-tick-borne-diseases-among-agro-pastoral-communities-in-southern-highlands-tanzania
#15
Isack Ibrahim Kerario, Martin Simuunza, Emmanuel L K Laisser, Sebastian Chenyambuga
Aim: The current study was conducted to assess the farmers' knowledge and management practices on ticks and tick-borne diseases (TBDs) through individual interview using a structured questionnaire in Mbarali and Momba districts of Mbeya region. Materials and Methods: A total of 240 households, 120 from each district were asked to mention TBDs of cattle which they thought were the most important in their localities and period of the year when the diseases occurred more frequently...
January 2018: Veterinary World
https://www.readbyqxmd.com/read/29479151/detection-of-ehrlichia-anaplasma-and-babesia-spp-in-dogs-of-cebu-philippines
#16
Rochelle Haidee D Ybañez, Adrian P Ybañez, Lyra Lee A Arnado, Laila Monika P Belarmino, Knowlie Gay F Malingin, Paul Bien C Cabilete, Ziggy Ryan O Amores, Maxfrancis G Talle, Mingming Liu, Xuenan Xuan
Background: Ehrlichia , Anaplasma , and Babesia spp. are canine pathogens transmitted by the Rhipicephalus sanguineus tick which can cause varied clinical signs. These pathogens have been investigated in the Philippines, but coinfection has not been reported yet. Aim: The aim of this study was to evaluate the presence of Ehrlichia/Anaplasma and Babesia spp. in Philippine dogs. Materials and Methods: A total of 100 dogs from seven different veterinary establishments in Cebu, Philippines, were examined for Ehrlichia/Anaplasma and Babesia spp...
January 2018: Veterinary World
https://www.readbyqxmd.com/read/29468169/severe-human-granulocytic-anaplasmosis-with-significantly-elevated-ferritin-levels-in-an-immunocompetent-host-in-pennsylvania-a-case-report
#17
Mona L Camacci, Ronaldo Paolo Panganiban, Zachary Pattison, Kamyar Haghayeghi, Alexander Daly, Cindy Ojevwe, Ryan J Munyon
Human granulocytic anaplasmosis (HGA) is a tick-borne, infectious disease caused by Anaplasma phagocytophilum that generally presents with nonspecific symptoms such as fever, chills, headache, malaise, and myalgia. If not treated immediately, HGA can cause hemophagocytic lymphohistiocytosis (HLH), a well-documented but underrecognized sequela of severe HGA. In this article, we report a case of severe HGA with hyperferritinemia in a 74-year-old male from Central Pennsylvania who initially presented with recurrent fevers, nausea, and malaise to our emergency department and was subsequently discharged home that same day...
January 2018: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29453420/a-multiplex-serologic-platform-for-diagnosis-of-tick-borne-diseases
#18
Rafal Tokarz, Nischay Mishra, Teresa Tagliafierro, Stephen Sameroff, Adrian Caciula, Lokendrasingh Chauhan, Jigar Patel, Eric Sullivan, Azad Gucwa, Brian Fallon, Marc Golightly, Claudia Molins, Martin Schriefer, Adriana Marques, Thomas Briese, W Ian Lipkin
Tick-borne diseases are the most common vector-borne diseases in the United States, with serology being the primary method of diagnosis. We developed the first multiplex, array-based assay for serodiagnosis of tick-borne diseases called the TBD-Serochip. The TBD-Serochip was designed to discriminate antibody responses to 8 major tick-borne pathogens present in the United States, including Anaplasma phagocytophilum, Babesia microti, Borrelia burgdorferi, Borrelia miyamotoi, Ehrlichia chaffeensis, Rickettsia rickettsii, Heartland virus and Powassan virus...
February 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29422446/molecular-detection-and-phylogenetic-analysis-of-anaplasma-marginale-and-anaplasma-centrale-amongst-transhumant-cattle-in-north-eastern-uganda
#19
Charles Byaruhanga, Nicola E Collins, Darryn L Knobel, Zamantungwa T H Khumalo, Mamohale E Chaisi, Marinda C Oosthuizen
There is little molecular data from Anaplasma marginale and Anaplasma centrale isolates from cattle in Uganda. Between November 2013 and January 2014, blood was collected from 240 cattle in 20 randomly-selected herds in two districts of the Karamoja Region in north-eastern Uganda. A duplex quantitative real-time polymerase chain reaction (qPCR) assay was used to detect and determine the prevalence of A. marginale (targeting the msp1β gene) and A. centrale (targeting the groEL gene). The qPCR assay revealed that most cattle (82...
February 1, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29415034/molecular-characterization-of-the-recombinant-protein-rmlti-bmcg-ltb-protective-immunity-against-rhipicephalus-boophilus-microplus
#20
Bárbara Guimarães Csordas, Rodrigo Casquero Cunha, Marcos Valério Garcia, Sérgio Silva da Silva, Fábio Leivas Leite, Renato Andreotti
The bovine tick Rhipicephalus (Boophilus) microplus is found in several tropical and subtropical regions of the world. This parasite transmits pathogens that cause disease, such as babesiosis (Babesia bovis and B. bigemina) and anaplasmosis (Anaplasma marginale). Tick infestations cause enormous livestock losses, and controlling tick infestations and the transmission of tick-borne diseases remains a challenge for the livestock industry. Because the currently available commercial vaccines offer only partial protection against R...
2018: PloS One
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