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Sacral nerve stimulation

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https://www.readbyqxmd.com/read/28298708/outcomes-of-sacral-nerve-stimulation-for-faecal-incontinence-in-northern-ireland
#1
G W Irwin, B V Dasari, R Irwin, D Johnston, K Khosraviani
BACKGROUND: Sacral nerve root stimulation (SNS) is an effective and developing therapy for faecal incontinence, a debilitating condition that can result in social and personal incapacitation. OBJECTIVES: The objectives of this study are to assess the morbidity of the procedure, improvement in the incontinence scores and Quality of Life (QoL) following SNS. MATERIALS AND METHODS: Patients were identified from the Northern Ireland regional SNS service from 2006 to 2012...
January 2017: Ulster Medical Journal
https://www.readbyqxmd.com/read/28277856/electrical-therapies-for-gastrointestinal-motility-disorders
#2
Jiande D Z Chen, Jieyun Yin, Wei Wei
Gastrointestinal (GI) motility disorders are common in clinical settings, including esophageal motility disorders, gastroesophageal reflux disease, functional dyspepsia, gastroparesis, chronic intestinal pseudo-obstruction, post-operative ileus, irritable bowel syndrome, diarrhea and constipation. While a number of drugs have been developed for treating GI motility disorders, few are currently available. Emerging electrical stimulation methods may provide new treatment options for these GI motility disorders...
March 6, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28267690/pathophysiology-and-therapeutic-options-for-fecal-incontinence
#3
Alexandra Guillaume, Ahmed E Salem, Patricia Garcia, Bani Chander Roland
Fecal incontinence (FI), defined as the involuntary loss of solid or liquid feces through the anus is a prevalent condition with significant effects on quality of life. FI can affect individuals of all ages and in many cases greatly impairs quality of life but, incontinent patients should not accept their debility as either inevitable or untreatable. The severity of incontinence can range from unintentional elimination of flatus to the complete evacuation of bowel contents. It is reported to affect up to 18% of the population, with a prevalence reaching as high as 50% in nursing home residents...
April 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28265107/use-of-sacral-nerve-stimulation-for-the-treatment-of-overlapping-constipation-and-fecal-incontinence
#4
Gouri Sreepati, Toyia James-Stevenson
BACKGROUND Fecal incontinence and constipation are common gastrointestinal complaints, but rarely occur concurrently. Management of these seemingly paradoxical processes is challenging, as treatment of one symptom may exacerbate the other. CASE REPORT A 51-year-old female with lifelong neurogenic bladder secondary to spina bifida occulta presented with progressive symptoms of daily urge fecal incontinence as well as hard bowel movements associated with straining and a sensation of incomplete evacuation requiring manual disimpaction...
March 7, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28255769/management-of-device-related-complications-after-sacral-neuromodulation-for-lower-urinary-tract-disorders-in-women-a-single-center-experience
#5
Tilemachos Kavvadias, Markus Huebner, Sara Yvonne Brucker, Christl Reisenauer
PURPOSE: This study is aimed at presenting and discussing the device-related complication management during a 5-year period, of the sacral nerve modulation (SNM), in a tertiary-care university unit. METHODS: This is a retrospective chart review of all women, who received SNM in our department between May 2011 and May 2016. All two-stage procedures were performed by the same experienced surgeon and according to our strict protocol of patients' selection and follow-up...
March 3, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28224396/sacral-neuromodulation-implant-infection-risk-factors-and-prevention
#6
REVIEW
Calvin Lee, Javier Pizarro-Berdichevsky, Marisa M Clifton, Sandip P Vasavada
Device infection is one of the most common complications of sacral nerve stimulator placement and occurs in approximately 3-10% of cases. Infection is a serious complication, as it often requires complete explantation of the device. Not much is known regarding risk factors for and methods of preventing infection in sacral nerve stimulation. Multiple risk factors have been linked to device infection including prolonged percutaneous testing and choice of preoperative antibiotic. Methods of infection prevention have also been studied recently, including antibiotic-impregnated collage and type of skin preparation...
February 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28192077/impact-of-age-and-comorbidities-on-utilization-of-sacral-neuromodulation
#7
Anna Er Faris, Bradley C Gill, Javier Pizarro-Berdichevsky, Elodi Dielubanza, Marisa M Clifton, Henry Okafor, Howard B Goldman, Courtenay K Moore, Raymond R Rackley, Sandip P Vasavada
PURPOSE: To investigate the influence of patient age on sacral nerve stimulation(SNS) trial outcomes, device implantation, and treatment durability. MATERIALS AND METHODS: A database of all SNS procedures between 2012-2014 at a high-volume institution was analyzed for associations of age with SNS indication, trial stimulation success, device revision, and device explantation. RESULTS: Within a 356 patient cohort, non-obstructive urinary retention and urgency- frequency patients were younger than those with urgency urinary incontinence...
February 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28181378/sacral-nerve-stimulation-can-alleviate-symptoms-of-bowel-dysfunction-after-colorectal-resections
#8
Diane Mege, Guillaume Meurette, Veronique Vitton, Anne-Marie Leroi, Valerie Bridoux, Philippe Zerbib, Igor Sielezneff
BACKGROUND: Poor functional results, such as faecal incontinence (FI), low anterior resection syndrome (LARS) or high stool frequency can occur after colorectal resections; including proctocolectomy with ileal pouch-anal anastomosis (IPAA), rectal resection and left hemicolectomy. Management of these patients is an issue, and some case-reports have demonstrated the effectiveness of sacral nerve stimulation (SNS) in such situations. OUR AIM: was to analyse the effectiveness of SNS on poor functional results and on the quality of life, after different colorectal resections...
February 9, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28150422/successful-restoration-of-fecal-continence-using-sacral-nerve-stimulation-following-chemoradiation-and-transanal-excision-of-an-anal-melanoma-with-partial-internal-anal-sphincter-resection-a-case-report
#9
Tyler Cameron Tolopka, Craig A Messick
OBJECTIVE: This case report provides evidence for our hypothesis that use of a sacral nerve stimulator may be considered in patients with fecal incontinence (FI) following chemoradiation and transanal operations in the setting of cancer including partial internal sphincter resections. MATERIALS AND METHODS: A 57-year-old female with a history of anal melanoma was treated with neoadjuvant chemoradiation followed by wide local, transanal tumor excision with partial internal anal sphincter resection that resulted in ≥2 full fecal incontinent episodes/week with gas, liquid, and solid stool leakage ≥10/day requiring pad changes...
February 1, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28071947/presacral-abscess-as-a-rare-complication-of-sacral-nerve-stimulator-implantation
#10
A Gumber, S Ayyar, H Varia, S Pettit
A 50-year-old man with intractable anal pain attributed to proctalgia fugax underwent insertion of a sacral nerve stimulator via the right S3 vertebral foramen for pain control with good symptomatic relief. Thirteen months later, he presented with signs of sepsis. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a large presacral abscess. MRI demonstrated increased enhancement along the pathway of the stimulator electrode, indicating that the abscess was caused by infection introduced at the time of sacral nerve stimulator placement...
January 10, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28035463/sacral-nerve-stimulation-for-faecal-incontinence-in-patients-with-sacral-malformation
#11
M Brunner, Z Cui, K E Matzel
INTRODUCTION: Sacral nerve stimulation (SNS) is a common and effective treatment for faecal incontinence (FI), but accessibility of the sacral nerves is mandatory. In some cases, electrode placement fails for unknown reasons. A frequent cause could be sacral malformations, which have a high incidence (up to 24.1%) and can be unsuspected. METHODS AND RESULTS: We report two patients with FI consequent to congenital anorectal malformation and associated sacral malformation...
December 30, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28000184/-to-improve-the-surgical-outcome-of-chronic-constipation-from-bed-to-the-bench
#12
Weidong Tong, Li Wang
The prevalence of chronic constipation is about 16% in adults, and increases with age, especially after 60 years old. Usually, surgical intervention is recommended to patients with long standing intractable constipation, who have undergone various conservative therapies. Lots of surgical procedures have been reported for different kinds of constipation, including slow transit, outlet obstruction, etc. For slow transit constipation, total or subtotal colectomy is commonly used. Merely for the internal rectal prolapse, at least 10 procedures are commonly adopted in clinic...
December 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28000183/-operation-key-points-and-efficacy-evaluation-of-jinling-procedure-for-mixed-refractory-constipation
#13
Jun Jiang, Qiyi Chen
For chronic transit constipation (STC), surgery should be considered when all pharmacological interventions, biofeedback, and sacral nerve stimulation failed to relieve severe symptoms. Chronic functional constipation can be subdivided into three subtypes: colonic slow-transit constipation, outlet obstruction and mixed refractory constipation. The pathological changes of colonic slow transit and outlet obstruction constipation can influence each other. Mixed refractory constipation accounts for 90.2% of chronic constipation...
December 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27997083/acute-sacral-nerve-stimulation-reduces-visceral-mechanosensitivity-in-a-cross-organ-sensitization-model
#14
L D Langlois, E Le Long, M Meleine, M Antor, K Atmani, P Dechelotte, A M Leroi, G Gourcerol
BACKGROUND: Sacral nerve stimulation (SNS) is a surgical treatment of fecal and urinary incontinence that consists of inserting a stimulating electrode into one of the s3 or s4 sacral holes. In addition to the benefit of SNS in the treatment of incontinence, recent studies showed that SNS is effective in the treatment of irritable bowel syndrome as well as bladder pain syndrome. The aim of this study was to evaluate the effect of SNS on visceral mechanosensitivity in a cross-organ sensitization rat model...
November 7, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27935110/involvement-of-opioid-receptors-in-inhibition-of-bladder-overactivity-induced-by-sacral-neuromodulation-in-pigs-a-possible-action-mechanism
#15
Xing Li, Limin Liao, Guoqing Chen, Zhaoxia Wang, Han Deng
AIMS: To determine the role of opioid receptors in the inhibition of bladder overactivity by sacral neuromodulation (SNM) in pigs, and explore the possible mechanism of SNM. METHODS: Both implant-driven stimulators of the S3 spinal nerve were implanted in seven pigs. Naloxone and tramadol were administered. Multiple cystometrograms were performed to determine the effects of SNM and opioid receptors on the micturition reflex by infusing normal saline (NS) or acetic acid (AA)...
December 9, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27920880/conditional-electrical-stimulation-in-animal-and-human-models-for-neurogenic-bladder-working-toward-a-neuroprosthesis
#16
C R Powell
Sacral neuromodulation has had a tremendous impact on the treatment of urinary incontinence and lower urinary tract symptoms for patients with neurologic conditions. This stimulation does not use real-time data from the body or input from the patient. Incorporating this is the goal of those pursuing a neuroprosthesis to enhance bladder function for these patients. Investigators have demonstrated the effectiveness of conditional (also called closed-loop) feedback in animal models as well as limited human studies...
December 2016: Current Bladder Dysfunction Reports
https://www.readbyqxmd.com/read/27887683/sacral-nerve-stimulation-allows-for-decreased-antegrade-continence-enema-use-in-children-with-severe-constipation
#17
Peter L Lu, Lindsey Asti, Daniel L Lodwick, Kristine M Nacion, Katherine J Deans, Peter C Minneci, Steven Teich, Seth A Alpert, Desale Yacob, Carlo Di Lorenzo, Hayat M Mousa
BACKGROUND: Sacral nerve stimulation (SNS) can be beneficial for children with constipation, but no studies have focused on children with constipation severe enough to require antegrade continence enemas (ACEs). Our objective was to evaluate the efficacy of SNS in children with constipation treated with ACE. METHODS: Using a prospective patient registry, we identified patients <21years old who were receiving ACE prior to SNS placement. We compared ACE/laxative usage, PedsQL Gastrointestinal Symptom Scale (GSS), Fecal Incontinence Quality of Life Scale (FIQL), Fecal Incontinence Severity Index (FISI), and Vancouver Dysfunctional Elimination Syndrome Score (DES) at baseline and progressive follow-up time intervals...
November 10, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27868230/no-immediate-effect-on-urodynamic-parameters-during-transcutaneous-electrical-nerve-stimulation-tens-in-children-with-overactive-bladder-and-daytime-incontinence-a-randomized-double-blind-placebo-controlled-study
#18
Luise Borch, Soeren Rittig, Konstantinos Kamperis, Birgitte Mahler, Jens Christian Djurhuus, Soeren Hagstroem
AIM: To evaluate the immediate effect on natural fill urodynamic parameters and bladder function during transcutaneous electrical nerve stimulation (TENS) in children with overactive bladder (OAB) and daytime urinary incontinence (DUI). METHODS: In this double-blind, placebo-controlled study, 24 children with severe OAB and DUI (mean age 8.5 ± 1.2 years) underwent 48-h natural fill urodynamics. After 24 h of baseline investigation, the children were randomized to either active continuous TENS (n = 12) or placebo TENS (n = 12) over the sacral S2-S3 outflow...
November 21, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27844258/surface-anatomical-landmarks-for-the-location-of-posterior-sacral-foramina-in-sacral-nerve-stimulation
#19
A Povo, M Arantes, K E Matzel, J Barbosa, M A Ferreira, D Pais, A Rodríguez-Baeza
BACKGROUND: Sacral nerve stimulation is a common treatment for various pelvic floor disorders. It consists of the percutaneous introduction of electrodes through the posterior sacral foramina for therapeutic stimulation of the target sacral spinal nerve. The aim of our study was to determine the surface anatomical landmarks of the sacrum to facilitate identification of the posterior sacral foramina. METHODS: This study was conducted on 20 human cadavers. The cadavers were placed in a prone position, and all the soft tissues of the sacral region were removed to allow exposure of the osseous structures...
December 2016: Techniques in Coloproctology
https://www.readbyqxmd.com/read/27836361/ultrasound-guided-intrasphincteric-botulinum-toxin-injection-relieves-obstructive-defecation-due-to-hirschsprung-s-disease-and-internal-anal-sphincter-achalasia
#20
COMPARATIVE STUDY
Joseph T Church, Samir K Gadepalli, Toghrul Talishinsky, Daniel H Teitelbaum, Marcus D Jarboe
PURPOSE: Chronic obstructive defecation can occur in patients with Hirschsprung Disease (HD) and internal anal sphincter (IAS) achalasia. Injection of Botulinum Toxin (BoTox) into the IAS can temporarily relieve obstructive defecation, but can be challenging when performed by tactile sense alone. We compared results of BoTox injections with and without ultrasound (US) guidance. METHODS: We retrospectively reviewed BoTox injections into the IAS for obstructive defecation over 5years...
January 2017: Journal of Pediatric Surgery
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