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Sacral nerve stimulation

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https://www.readbyqxmd.com/read/29142293/neural-pathways-for-colorectal-control-relevance-to-spinal-cord-injury-and-treatment-a-narrative-review
#1
REVIEW
Brid Callaghan, John B Furness, Ruslan V Pustovit
STUDY DESIGN: Narrative review. OBJECTIVES: The purpose is to review the organisation of the nerve pathways that control defecation and to relate this knowledge to the deficits in colorectal function after SCI. METHODS: A literature review was conducted to identify salient features of defecation control pathways and the functional consequences of damage to these pathways in SCI. RESULTS: The control pathways for defecation have separate pontine centres under cortical control that influence defecation...
November 16, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29115915/neuromodulation-in-multiple-sclerosis
#2
Hesham Abboud, Eddie Hill, Junaid Siddiqui, Alessandro Serra, Benjamin Walter
Neuromodulation, or the utilization of advanced technology for targeted electrical or chemical neuronal stimulation or inhibition, has been expanding in several neurological subspecialties. In the past decades, immune-modulating therapy has been the main focus of multiple sclerosis (MS) research with little attention to neuromodulation. However, with the recent advances in disease-modifying therapies, it is time to shift the focus of MS research to neuromodulation and restoration of function as with other neurological subspecialties...
November 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29112568/sacral-nerve-stimulation-for-fecal-incontinence-how-long-should-the-test-phase-be
#3
Elsa Lambrescak, Vincent Wyart, Guillaume Meurette, Jean-Luc Faucheron, Christian Thomas, Patrick Atienza, Paul-Antoine Lehur, Isabelle Etienney
BACKGROUND: Decision-making for pulse generator implantation for sacral nerve stimulation in the management of fecal incontinence is based on the results of a test phase. Its duration is still a matter of debate. OBJECTIVE: The purpose of this study was to determine whether an early positive response during the test phase could predict implantation of a permanent sacral nerve pulse generator. DESIGN: This was a short-term observational cohort study...
December 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29102296/sacral-neuromodulation-for-faecal-incontinence-10-years-experience-at-a-scottish-tertiary-centre
#4
Hoey Koh, Stephen McSorley, Sarah Hunt, Martha Quinn, Graham MacKay, John Anderson
INTRODUCTION: Sacral nerve stimulation (SNS) is increasingly popular in the management of faecal incontinence. This paper reports the first 10-year experience of SNS in the management of faecal incontinence at a tertiary referral centre. Data was collected in a prospectively maintained database. RESULTS: In total 130 patients were referred. The majority were women (94%) under 75-year-old (98%). Seven patients were found to have full-thickness rectal prolapse at the initial work-up and proceeded to rectopexy...
October 25, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29071144/does-sacral-pulsed-electromagnetic-field-therapy-have-a-better-effect-than-transcutaneous-electrical-nerve-stimulation-in-patients-with-neurogenic-overactive-bladder
#5
Lamyaa A Fergany, Husain Shaker, Magdy Arafa, Mohamed S Elbadry
OBJECTIVE: To compare the effectiveness of pulsed electromagnetic field therapy (PEMFT) and transcutaneous electrical nerve stimulation (TENS) on neurogenic overactive bladder dysfunction (OAB) in patients with spinal cord injury (SCI). PATIENTS AND METHODS: In all, 80 patients [50 men and 30 women, with a mean (SD) age of 40.15 (8.76) years] with neurogenic OAB secondary to suprasacral SCI were included. They underwent urodynamic studies (UDS) before and after treatment...
June 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29065235/comparison-of-active-stimulating-electrodes-of-sacral-neuromodulation
#6
Xin Su, Matthew Cutinella, Jason E Agran, David A Dinsmoor
OBJECTIVE: The goal of this study was to compare the motor response to sacral neuromodulation (SNM) with different pairs of stimulating electrodes in anesthetized and awake sheep. MATERIALS AND METHODS: Similar to SNM clinical use in humans, the InterStim(®) quadripolar tined lead was implanted adjacent to the S3 nerve root in sheep and bipolar stimulation was configured with one electrode negative and one electrode positive on the four contacts (0 most distal to device, 1, 2, and 3 most proximal)...
October 24, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29063170/-neuromodulation-of-lower-urinary-tract-dysfunction
#7
REVIEW
T M Kessler, S de Wachter
Neuromodulative procedures such as transcutaneous electrical nerve stimulation (TENS), transcutaneous/percutaneous tibial nerve stimulation (TTNS/PTNS), and sacral neuromodulation (SNM) are promising second-line treatments for refractory lower urinary tract dysfunction. Using these therapies, both storage and voiding disorders but also bowel dysfunction might be successfully treated. Although the mechanism of action of neuromodulation is not well understood, it seems to involve modulation of spinal cord reflexes and brain networks by peripheral afferents (genital/rectal, tibial and sacral afferents in the case of TENS, TTNS/PTNS, and SNM, respectively)...
October 23, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29046985/new-devices-and-technologies-for-the-management-of-overactive-bladder
#8
REVIEW
Juan M Guzman-Negron, Howard B Goldman
PURPOSE OF REVIEW: Overactive bladder (OAB) affects millions of people in the USA and has a significant impact on their quality of life. Despite having a number of safe and effective ways of managing refractory OAB patients, there are many promising new technologies actively being studied and developed for the treatment of this population. This review examines current new devices and technologies under study for the treatment of OAB. RECENT FINDINGS: Modifications to already established therapies such as sacral nerve stimulation (SNS) or tibial nerve stimulation (TNS) are currently being studied for refractory OAB...
October 18, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/29024404/removal-of-sacral-nerve-stimulation-devices-for-magnetic-resonance-imaging-what-happens-next
#9
Jessica C Lloyd, Bradley C Gill, Javier Pizarro-Berdichevsky, Howard B Goldman
INTRODUCTION: Sacral neuromodulation (SNM) devices (Medtronic, Minneapolis, MN, USA) are not approved to undergo magnetic resonance imaging (MRI) of sites other than the head. When MRIs are required, devices are often removed prior to imaging. We reviewed the prevalence of device removal for MRI at a large academic institution and the subsequent clinical course of these patients. METHODS: A retrospective review of all SNM explants from 2009-2015 was performed. Cases explanted for MRI were analyzed to collect demographics, clinical characteristics, and postremoval management...
October 11, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28975677/sacral-neuromodulation-standardized-electrode-placement-technique
#10
Klaus E Matzel, Emmanuel Chartier-Kastler, Charles H Knowles, Paul A Lehur, Arantxa Muñoz-Duyos, Carlo Ratto, Mona B Rydningen, Michael Sørensen, Philip van Kerrebroeck, Stefan de Wachter
INTRODUCTION: Sacral neuromodulation (SNM) (sacral nerve stimulation SNS) has become an established therapy for functional disorders of the pelvic organs. Despite its overall success, the therapy fails in a proportion of patients. This may be partially due to inadequate electrode placement with suboptimal coupling of the electrode and nerve. Based on these assumptions the technique of sacral spinal neuromodulation has been redefined. All descriptions relate to the only currently available system licensed for all pelvic indications (Medtronic Interstim(®) )...
October 4, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28960926/surgery-for-constipation-systematic-review-and-practice-recommendations-results-v-sacral-nerve-stimulation
#11
REVIEW
S A Pilkington, C Emmett, C H Knowles, J Mason, Y Yiannakou
AIM: To assess the outcomes of sacral nerve stimulation in adults with chronic constipation. METHOD: Standardised methods and reporting of benefits and harms were used for all CapaCiTY reviews that closely adhered to PRISMA 2016 guidance. Main conclusions were presented as summary evidence statements with a summative Oxford Centre for Evidence-Based Medicine (2009) level. RESULTS: Seven articles were identified, providing data on outcomes in 375 patients...
September 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28960925/surgery-for-constipation-systematic-review-and-clinical-guidance-paper-1-introduction-methods
#12
REVIEW
C H Knowles, U Grossi, E J Horrocks, D Pares, P F Vollebregt, M Chapman, S R Brown, M Mercer-Jones, A B Williams, R J Hooper, N Stevens, J Mason
AIM: This manuscript provides the introduction and detailed methodology used in subsequent reviews to assess the outcomes of surgical interventions with the primary intent of treating chronic constipation in adults and to develop recommendations for practice. METHOD: PRISMA guidance was adhered to throughout. A literature search was performed in public databases between January 1960 and February 2016. Studies that fulfilled strictly-defined PICOS (patients, interventions, controls, outcome, and study design) criteria were included...
September 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28960557/searching-for-a-definition-for-pharmacologically-refractory-constipation-a-systematic-review
#13
Alex Yu Sen Soh, Jin-Yong Kang, Kewin Tien Ho Siah, Carmelo Scarpignato, Kok-Ann Gwee
BACKGROUND AND AIM: Surgery and other non-pharmacological treatments such as sacral nerve stimulation are used for the treatment of difficult to treat chronic constipation. Novel pharmacological therapeutic agents are also being introduced. To evaluate the efficacy of these treatments, it is imperative to have a consistent definition of pharmacologically refractory constipation. We carried out a systematic review of studies on refractory, difficult-to-treat or surgically treated constipation to determine the criteria various authors used to define this group of patients...
September 27, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28960131/blood-perfusion-changes-during-sacral-nerve-root-stimulation-versus-surface-gluteus-electrical-stimulation-on-in-seated-spinal-cord-injury
#14
Liang Qin Liu, Martin Ferguson-Pell
The objective of this article is to examine dynamic changes of ischial blood perfusion during sacral nerve root stimulation against surface functional electrical stimulation (FES). Fourteen adults with suprasacral spinal cord injury (SCI) were recruited. The gluteal maximus was activated by surface FES or stimulating sacral nerve roots by functional magnetic stimulation (FMS) or a sacral anterior root stimulator implant (SARS). Ischial skin index of hemoglobin (IHB) and oxygenation (IOX) was measured.Skin blood perfusion was significantly higher during FMS than the baseline (IHB 1...
September 29, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28931549/sacral-neuromodulation-blocks-pudendal-inhibition-of-reflex-bladder-activity-in-cats-insight-into-the-efficacy-of-sacral-neuromodulation-in-fowler-s-syndrome
#15
Xing Li, Jamie Uy, Michelle Yu, Shun Li, Katherine Theisen, Jeffrey Browning, Bing Shen, Jicheng Wang, James R Roppolo, William C de Groat, Changfeng Tai
This study tested the hypothesis that sacral neuromodulation, i.e. electrical stimulation of afferent axons in sacral spinal root, can block pudendal afferent inhibition of the micturition reflex. In α-chloralose anesthetized cats, pudendal nerve stimulation (PNS) at 3-5 Hz was used to inhibit bladder reflex activity while the sacral S1 or S2 dorsal root was stimulated at 15-30 Hz to mimic sacral neuromodulation and to block the bladder inhibition induced by PNS. The intensity threshold (T) for PNS or S1/S2 dorsal root stimulation (DRS) to induce muscle twitch of anal sphincter or toe was determined...
September 20, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28885782/evaluation-of-pulse-width-of-spinal-nerve-stimulation-in-a-rat-model-of-bladder-micturition-reflex
#16
Xin Su, Heather A Simenson, David A Dinsmoor, Heather D Orser
OBJECTIVES: The spinal nerve stimulation (SNS) evoked motor threshold (Tmot ) response across different pulse-widths (PWs) was first explored and a subset of selected stimulation PWs were further assessed with respect to bladder reflex contraction (BRC). MATERIALS AND METHODS: In anesthetized female rats, wire electrodes were placed under each of the L6 spinal nerves to produce bilateral SNS. The relationship of Tmot response with PW was analyzed using a monoexponential nonlinear regression...
September 8, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28877395/optimal-lead-positioning-in-sacral-neuromodulation-which-factors-are-related-to-treatment-outcome
#17
Ranjana Jairam, Tom Marcelissen, Gommert van Koeveringe, Philip van Kerrebroeck
OBJECTIVES: Sacral neuromodulation (SNM) is a well-established treatment for overactive bladder (OAB) and non-obstructive urinary retention (NOR). During test stimulation, the lead is positioned along the third sacral nerve, which ideally results in a response in all four contact points (active electrodes). However, it is unclear whether the position of the lead (depth, angle, deflection) and the number of active electrodes is related to the outcome of SNM. METHODS: All patients who underwent test stimulation using the tined lead between January 2011 and September 2016 were included in this retrospective study...
September 6, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28838787/surgical-interventions-and-the-use-of-device-aided-therapy-for-the-treatment-of-fecal-incontinence-and-defecatory-disorders
#18
Adil E Bharucha, Satish S C Rao, Andrea S Shin
The purpose of this clinical practice update expert review is to describe the key principles in the use of surgical interventions and device-aided therapy for managing fecal incontinence (FI) and defecatory disorders. The best practices outlined in this review are based on relevant publications, including systematic reviews and expert opinion (when applicable). Best Practice Advice 1: A stepwise approach should be followed for management of FI. Conservative therapies (diet, fluids, techniques to improve evacuation, a bowel training program, management of diarrhea and constipation with diet and medications if necessary) will benefit approximately 25% of patients and should be tried first...
December 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28832311/surgical-technique-for-removal-of-tined-lead-for-interstim
#19
Zhamshid Okhunov, Bilal Farhan, Ahmed Ahmed, Christopher Pulford, Gamal Ghoniem
INTRODUCTION: We aimed to introduce our technique describing the removal of a chronic implanted tined-lead in patients with a sacral neuromodulator implant. MATERIALS AND METHODS: We performed a retrospective review of patients who had chronic sacral neuromodulator (InterStim) implanted by a single surgeon from 2001 through 2015. This simple surgical technique was developed and successfully performed to remove the leads. Primary reasons for removal were elective due to poor symptoms control and failure to maintain response or lead migration...
August 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28799195/sacral-nerve-stimulation-for-constipation-and-fecal-incontinence-in-children-long-term-outcomes-patient-benefit-and-parent-satisfaction
#20
P L Lu, I J N Koppen, D K Orsagh-Yentis, K Leonhart, E J Ambeba, K J Deans, P C Minneci, S Teich, K A Diefenbach, S A Alpert, M A Benninga, D Yacob, C Di Lorenzo
OBJECTIVE: To evaluate the long-term efficacy of sacral nerve stimulation (SNS) in children with constipation and describe patient benefit and parent satisfaction. METHODS: Using a prospective patient registry, we identified patients <21 years old with constipation treated with SNS for >2 years. We compared symptoms, medical treatment, PedsQL Gastrointestinal Symptom Scale (GSS), Fecal Incontinence Quality of Life Scale (FIQL), and Fecal Incontinence Severity Index (FISI) before SNS and at follow-up...
August 10, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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