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https://www.readbyqxmd.com/read/28926461/nailfold-capillaroscopy-findings-mimicking-systemic-sclerosis-in-a-patient-with-port-wine-stain
#1
Serdar Can Güven, Özkan Varan, Hamit Küçük
No abstract text is available yet for this article.
September 19, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28915292/news-views-and-reviews-a-tool-for-my-laser-practice-i-simply-can-t-do-without-shining-a-light-on-my-favorite-light-source
#2
Eric F Bernstein
With laser surgery, what you see is what you get. Visualizing the target for treatment, be it a port-wine stain, a cluster of spider veins, a tattoo or freckles, or simply photodamaged skin requires seeing through surface reflections, dry skin, and often quite dark laser goggles. The tool that has been indispensable to me in my practice is the Syris v900L polarizing and magnifying headlamp. This indispensable tool makes laser treatment more precise, effective, and easier by truly shining a light on the subject of a laser treatment...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28866729/experimental-investigation-on-the-vascular-thermal-response-to-near-infrared-laser-pulses
#3
Dong Li, Bin Chen, Wenjuan Wu, Zhaoxia Ying
Port wine stains (PWS) are congenital vascular malformations that progressively darken and thicken with age. To improve the effect of laser therapy in clinical practice, thermal response of blood vessel to a 1064 nm Nd:YAG laser with controlled energy doses and pulse durations was evaluated using the dorsal skin chamber model. A total of 137 vessels with 30-300 μm diameters were selected from the dorsal skin of the mouse to match those capillaries in port wine stains. Experimental results showed that the thermal response of blood vessels to 1064 nm laser irradiation can be classified as follows: vessel dilation, coagulation, constriction with decreased diameter, complete constriction, hemorrhage, and collagen damage with increasing laser radiant exposure...
September 2, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28858925/pulsed-dye-laser-at-subpurpuric-settings-for-the-treatment-of-pulsed-dye-laser-induced-ecchymoses-in-patients-with-port-wine-stains
#4
Jeremy A Brauer, Joshua A Farhadian, Leonard J Bernstein, Yoon-Soo Bae, Roy G Geronemus
BACKGROUND: Post-procedure purpura is a major complaint of patients with port-wine stains (PWSs) treated with pulsed dye laser (PDL). OBJECTIVE: To assess the safety and efficacy of using PDL at nonpurpuric settings to treat ecchymoses that develop within PWSs after treatment with PDL. MATERIALS AND METHODS: Prospective, randomized, controlled study using 595-nm PDL for treatment of PWSs and laser-induced ecchymoses. Port-wine stains were treated in entirety at baseline...
August 30, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28758247/pulsed-dye-laser-treatment-of-port-wine-stains-in-children-useful-tips-to-avoid-general-anesthesia
#5
Adrián Alegre-Sánchez, Bibiana Pérez-García, Pablo Boixeda
Pulsed dye laser (PDL) treatment of port-wine stains (PWSs) in children is a common procedure performed in most laser units. Pain assessment in our younger patients is a major concern, especially in those with extensive PWSs. The use of general anesthesia (GA) results in pain-free treatment, but its effects on the developing brain are far from totally understood. Thus we propose some tips that avoid the use of GA in most of our young patients, including the use of topical anesthetics and cooling systems, large laser spot size and high frequencies, early and frequent treatment with parents present, and the "introduction" and "pressure" techniques, among others...
July 30, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28750153/safety-and-efficacy-of-dual-wavelength-laser-1064-nm-595-nm-for-treatment-of-non-treated-port-wine-stains
#6
Tianyou Wang, Da Chen, Jingyan Yang, Gang Ma, Wenxin Yu, Xiaoxi Lin
BACKGROUND: Patients with port-wine stain (PWS) suffer physically and psychologically because of the high incidence (0.3%-0.5%) of the disease. Pulsed dye laser (PDL) at 595 nm is the gold standard of the treatment for PWS. Nevertheless, clinicians intend to determine whether the dual wavelength laser (DWL) (595 nm PDL + 1064 nm Nd:YAG) is an adequate choice in the treatment of non-treated PWS. This study is the first prospective within-patient controlled research seeking to investigate the safety and efficacy of DWL for the treatment of non-treated PWS...
July 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28724825/a-rare-case-of-overlapping-sturge-weber-syndrome-and-klippel-trenaunay-syndrome-associated-with-bilateral-refractory-childhood-glaucoma
#7
Manju R Pillai, P P Hasini, Ashish Ahuja, S R Krishnadas
A 6-year-old girl presented with blurred vision and was found to have elevated intraocular pressure (IOP) and glaucomatous optic disc damage in both eyes. She also displayed capillary malformations on the face (port-wine stain), upper back and all four limbs, angiomatosis in the brain and had hypertrophy of the left upper and lower limbs typical of overlapping Sturge-Weber syndrome and Klippel-Trenaunay syndromes. She was initially managed with IOP lowering topical medications but required trabeculectomy in the right eye followed by Ahmed valve implantation in both eyes...
July 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28705519/acquired-port-wine-stain-fegeler-syndrome-a-report-of-3-cases
#8
J F Millán-Cayetano, J Del Boz, P García-Montero, M de Troya-Martín
No abstract text is available yet for this article.
July 11, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28698417/-intravenous-ablation-for-lower-extremity-varices-to-prevent-recurrent-pulmonary-embolism-in-klippel-trenaunay-syndrome-report-of-a-case
#9
Ikutaro Kigawa, Masahiro Aiba, Atsushi Ito
Klippel-Trenaunay syndrome( KTS) is a complex congenital anomaly characterized by lower extremity varix and venous malformations, port-wine stains, and soft tissue and bone hypertrophy. We present a case of a 35-year-old man of KTS with pulmonary embolism (PE). The patient was referred to our hospital complaining of the leg pain and sudden onset of dyspnea. Enhanced computed tomography (CT) showed lower extremity varices, superficial thrombophlebitis and bilateral pulmonary thrombi. No venous malformations except for varicose veins were revealed in the limbs or pelvis...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28681520/a-hairy-port-wine-stain-with-overlying-hyperhidrosis-on-the-thigh-of-a-child
#10
Vishal Gupta, Saurabh Bhatia, Sudheer Arava, Vinod K Sharma
No abstract text is available yet for this article.
July 6, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28663834/dermoscopy-guided-dark-field-multi-functional-optical-coherence-tomography
#11
Soonjae Kwon, Yeoreum Yoon, Bumju Kim, Won Hyuk Jang, Byungho Oh, Kee Yang Chung, Ki Hean Kim
Dermoscopy is a skin surface microscopic technique allowing specular reflection free observation of the skin, and has been used to examine pigmented skin lesions. However, dermoscopy has limitations in providing depth information due to lack of 3D resolution. In order to overcome the limitations, we developed dermoscopy guided multi-functional optical coherence tomography (MF-OCT) providing both high-contrast superficial information and depth-resolved structural, birefringent, and vascular information of the skin simultaneously...
March 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28657379/a-new-imaging-technique-for-assessment-of-the-effectiveness-of-long-pulse-nd-yag-532-nm-laser-in-treatment-of-facial-port-wine-stain
#12
Murtadha Hashim Al-Janabi, Noor Taha Ismaeel Ali, Karrar Dheiaa Mohammed, Muhsin A Al-Dhalimi, Sahib Neamh Abdul Wahid
BACKGROUND: PWS is a vascular malformation presented at birth and associated with a psychological problem to the patients. Many types the laser systems were used to solve this problem. AIM OF THE STUDY: to assess the efficacy of long-pulsed Nd:YAG 532 nm for the treatment of port wine stain both clinically and by imaging technique. PATIENTS AND METHODS: This is an Interventional therapeutic clinical study for the treatment of facial port-twine stain with long-pulsed, 532nm, Nd:YAG laser...
June 28, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28652904/successful-treatment-of-unilateral-klippel-trenaunay-syndrome-with-pulsed-dye-laser-in-a-2-week-old-infant
#13
Hoda Rahimi, Habib Hassannejad, Hamideh Moravvej
Introduction: Klippel-Trenaunay syndrome (KTS) is a rare congenital mesodermal abnormality characterized by varicose veins, cutaneous capillary malformation, as well as bone and soft tissue hypertrophy. Case Report: A 2-week-old female infant presented to our clinic because of vascular nevus and progressive enlargement of her right extremities and trunk since birth. The patient was treated with 595-nm pulsed-dye laser (PDL). Her port-wine stain (PWS) disappeared completely after third PDL session and the soft tissue hypertrophy stopped...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/28650740/in-vivo-investigation-of-the-safety-and-efficacy-of-pulsed-dye-laser-with-two-spot-sizes-in-port-wine-stain-treatment-a-prospective-side-by-side-comparison
#14
Wenxin Yu, Hanru Ying, Yijie Chen, Yajing Qiu, Hui Chen, Yunbo Jin, Xi Yang, Tianyou Wang, Gang Ma, Xiaoxi Lin
OBJECTIVE: Pulsed dye laser (PDL) with 7 and 10 mm spot sizes is widely used on a regular basis for the treatment of port-wine stain (PWS). BACKGROUND DATA: No studies have reported on the differences in efficacy outcomes resulting from the use of different laser spot sizes in the treatment of PWS by PDL. Thus, an in vivo investigation into the differences in safety and efficacy of treatment between two spot sizes (7 vs. 10 mm) of PWS by PDL was conducted. MATERIALS AND METHODS: A total of 35 PWS patients underwent three treatment sessions by using a 595 nm wavelength PDL (Vbeam(®), Candela Corp) with two laser settings: (1) 7 mm spot size, radiant exposure of 12 J/cm(2) and (2) 10 mm spot size, radiant exposure of 10 J/cm(2)...
September 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28647616/photodynamic-therapy-in-dermatology-beyond-non-melanoma-cancer-an-update
#15
REVIEW
Xiang Wen, Yong Li, Michael R Hamblin
Photodynamic therapy (PDT) employs a photosensitizer (PS) and visible light in the presence of oxygen, leading to production of cytotoxic reactive oxygen species, which can damage the cellular organelles and cause cell death. In dermatology, PDT has usually taken the form of topical application of a precursor in the heme biosynthesis pathway, called 5-aminolevulinic acid (or its methyl ester), so that an active PS, protoporphyrin IX accumulates in the skin. As PDT enhances dermal remodeling and resolves chronic inflamation, it has been used to treat cutaneous disorders include actinic keratoses, acne, viral warts, skin rejuvenation, psoriasis, localized scleroderma, some non-melanoma skin cancers and port-wine stains...
September 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28623992/near-infrared-fluorescence-lymphatic-imaging-of-klippel-tr%C3%A3-naunay-syndrome
#16
John C Rasmussen, Rodrick C Zvavanjanja, Melissa B Aldrich, Matthew R Greives, Eva M Sevick-Muraca
The relationship between lymphatic and venous malformations in Klippel-Trénaunay syndrome is difficult to assess. Herein the authors describe near-infrared fluorescence lymphatic imaging to assess the lymphatics of a subject with a large port-wine stain and right leg edema. Although lymphatic vessels in the medial, affected knee appeared dilated and perhaps tortuous, no definitive abnormal lymphatic pooling or propulsion was observed. The lymphatics in the affected limb were well defined but less numerous than in the contralateral limb, and active, contractile function was observed in all vessels...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28599054/coexistence-of-ephb1-and-ephrinb2-in-port-wine-stain-endothelial-progenitor-cells-contributes-to-clinicopathological-vasculature-dilatation
#17
W Tan, J Wang, F Zhou, L Gao, Y Rong, H Liu, A Sukanthanag, G Wang, M C Mihm, D-B Chen, J S Nelson
Port wine stain (PWS) is a vascular malformation characterized by a progressive dilatation of post-capillary venules, but the molecular pathogenesis remains obscure. We hypothesized that PWS endothelial cells (ECs) present a unique molecular phenotype that lead to pathoanatomic PWS vasculatures. We herein show multiple clinicopathologic features of PWS blood vessels during the development and progression of the disease. 1) There were no normal arterioles and venules phenotypically and morphologically observed in PWS skin; both arterioles and venules showed differentiation impairments, resulting in a reduction of arteriole-like vasculatures and defects in capillary loop formation in PWS lesions...
June 9, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28598555/experimental-and-numerical-investigation-on-the-transient-vascular-thermal-response-to-multi-pulse-nd-yag-laser
#18
Dong Li, Ruohui Li, Hao Jia, Bin Chen, Wenjuan Wu, Zhaoxia Ying
BACKGROUND AND OBJECTIVE: Port wine stains (PWS) are congenital vascular malformations that progressively darken and thicken with age. Laser therapy is currently the most effective way in clinical practice for PWS. A 1,064 nm Nd:YAG laser in the near-infrared band can achieve a deeper treatment depth compared to the current widely adopted pulsed dye laser. However, because of its relatively weak absorption by blood, single-pulse Nd:YAG laser requires high energy density to cause effective vessel damage, but may inflict undesirable burning to surrounding collagen...
June 9, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28584521/tranexamic-acid-encapsulating-thermosensitive-liposomes-for-site-specific-pharmaco-laser-therapy-of-port-wine-stains
#19
M Ingmar van Raath, Ruud Weijer, Gia Hung Nguyen, Bernard Choi, Anton I de Kroon, Michal Heger
Site-specific pharmaco-laser therapy (SSPLT) is a developmental stage treatment modality designed to non-invasively remove superficial vascular pathologies such as port wine stains (PWS) by combining conventional laser therapy with the prior administration of a prothrombotic and/or antifibrinolytic pharmaceutical-containing drug delivery system. For the antifibrinolytic SSPLT component, six different PEGylated thermosensitive liposomal formulations encapsulating tranexamic acid (TA), a potent antifibrinolytic lysine analogue, were characterized for drug:lipid ratio, encapsulation efficiency, size, endovesicular TA concentration (CTA), phase transition temperature (Tm), and assayed for heat-induced TA release...
August 2016: Journal of Biomedical Nanotechnology
https://www.readbyqxmd.com/read/28578999/utility-and-tolerability-of-the-long-pulsed-1064-nm-neodymium-yttrium-aluminum-garnet-lp-nd-yag-laser-for-treatment-of-symptomatic-or-disfiguring-vascular-malformations-in-children-and-adolescents
#20
Aditi S Murthy, Annelise Dawson, Deepti Gupta, Shanna Spring, Kelly M Cordoro
BACKGROUND: Vascular malformations manifest with pain, bleeding, disability, and disfigurement in a subset of children. There are scant data available on the utility and tolerability of laser surgery for symptomatic or disfiguring non-port-wine stain vascular malformations in children. OBJECTIVE: The objective of this study was to determine the utility and tolerability of the 1064-nm long-pulsed neodymium:yttrium-aluminum-garnet (LP Nd:YAG) laser for treatment of symptomatic or disfiguring vascular malformations in children...
June 1, 2017: Journal of the American Academy of Dermatology
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