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Krisztina Somogyári, Péter Móricz, Imre Gerlinger, László Kereskai, István Szanyi, Ildikó Takács
The aim of this study was to evaluate the short and medium-term effects of radiofrequency (RF) and potassium titanyl phosphate (KTP) and neodymium-yttrium-aluminum garnet (Nd:YAG) laser treatment on the inferior turbinate mucosa in a porcine model. Following randomization, the inferior turbinates were treated either with RF submucosally or with the KTP or the Nd:YAG laser on the surface under videoendoscopic control. Tissue samples were taken at the end of postoperative weeks 1 and 6, and were evaluated macroscopically and histopathologically...
October 11, 2016: Surgical Innovation
Yasushi Yamada, Jun Furusawa, Yoshiki Sugimura, Isao Kuromastu
PURPOSE: To evaluate the long-term outcomes and safety photoselective vaporization of the prostate (PVP). PATIENTS AND METHODS: From April 2005 to December 2015, a total of 1154 patients with benign prostatic hyperplasia (BPH) underwent PVP. The type of Green Light laser was an 80W potassium-titanyl-phosphate (KTP) laser and later a 120W lithium triborate (LBO) laser. Before and after surgery, the International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), post-void residual volume (PVR), prostate-specific antigen (PSA) level and prostate volume were assessed regularly...
October 12, 2016: Journal of Endourology
Kei Negishi, Shiho Tanaka, Saori Tobita
BACKGROUND AND OBJECTIVE: Hyperpigmentation is a common concern in Asian patients. Few published studies address overall skin rejuvenation in this group using long-pulse (LP) laser to target pigmentation and stimulate dermal remodeling. The LP KTP 532-nm laser (LP 532-nm) is used primarily to remove epidermal lesions, while the LP Nd: YAG 1064-nm laser (LP 1064-nm) is used to stimulate dermal remodeling in Asian patients with varying efficacy. The LP 532-nm used alone and in combination with LP 1064-nm to reduce pigmentation and rejuvenate skin was previously evaluated in lighter skin, but not in Asian skin...
September 8, 2016: Lasers in Surgery and Medicine
Seiya Hanamoto, Eisuke Hasegawa, Norihide Nakada, Naoyuki Yamashita, Hiroaki Tanaka
Photoproducts of pharmaceuticals have been studied in order not to overlook their potential risks to aquatic organisms. However, no studies have verified an equation for predicting the fate of photoproducts in aquatic environment (Poiger equation) by field measurements, leaving uncertainties in its practical utility. Therefore, we conducted this study to test the applicability of the Poiger equation to 3-ethylbenzophenone (EBP), a photoproduct of ketoprofen (KTP). Photolysis experiments determined the fraction of KTP transformed into EBP as 0...
September 1, 2016: Science of the Total Environment
J-L Tambasco, A Boes, L G Helt, M J Steel, A Mitchell
We introduce a method for shaping the spectral response of nonlinear light sources by tailoring the quasi-phase matching. Our algorithm relies on engineering the poling to accurately trace a generated target signal field amplitude to determine the desired nonlinearity profile. The proposed poling algorithm results in a poling pattern that is more robust to manufacture, as all domain inversions are of equal width. The poling pattern is verified using a nonlinear beam propagation method simulation. This approach is applied to achieve Gaussian-shaped phase matching along a potassium titanyl phosphate (KTP) crystal in order to generate pure heralded single photons of spectral purity ~0...
August 22, 2016: Optics Express
A Jain, S J Frampton, R Sachidananda, P K Jain
OBJECTIVE: To evaluate the short- to medium-term effectiveness of potassium titanyl phosphate (KTP) laser Dermastat in patients with recurrent anterior epistaxis. METHOD: Fifty-eight patients presenting with recurrent anterior epistaxis were treated using potassium titanyl phosphate laser Dermastat. Those with recurrent epistaxis arising from prominent vessels in Little's area, and/or those for whom treatment with silver nitrate cautery failed, were included. The main outcome measure was resolution of epistaxis at two months...
September 2016: Journal of Laryngology and Otology
Russell J Barbour, Tyler Brewer, Zeb W Barber
We characterize the intermodulation distortion of high power and efficient frequency conversion of modulated optical signals based on sum frequency generation (SFG) in a periodically poled potassium titanyl phosphate (KTP) waveguide. Unwanted frequency two-tone spurs are generated near the converted signal via a three-step cascaded three-wave mixing process. Computer simulations describing the process are presented along with the experimental measurements. High-conversion efficiencies and large spur-free dynamic range of the converted optical signal are demonstrated...
August 1, 2016: Optics Letters
Samuel N Helman, Michael J Pitman
OBJECTIVES/HYPOTHESIS: Many laryngopharyngeal disorders are effectively managed in the office. Herein, an in-office method utilizing the 532-nm potassium-titanyl-phosphate (KTP) laser for the treatment of benign laryngeal and vallecular mucoceles is described. STUDY DESIGN: Retrospective case review. METHODS: A review was performed of patients who had their vallecular or laryngeal mucoceles marsupialized in the office using KTP laser. RESULTS: Outcomes included long-term follow-up laryngoscopy for evidence of recurrence, significant intraprocedural complications, tolerance of the procedure, final pathology of the specimen, and resolution of symptoms...
July 20, 2016: Laryngoscope
Ming-Li Liang, Chun-Li Hu, Fang Kong, Jiang-Gao Mao
The first bismuth selenite fluoride, BiFSeO3, was obtained by aliovalent substitution of 2D BiOIO3. Its structure features a 3D network composed of 1D [BiF](2+) chains interconnected by SeO3 groups. BiFSeO3 exhibits a very strong second harmonic generation (SHG) effect of about 13.5 times that of KH2PO4 (KDP) under 1064 nm laser radiation and 1.1 times that of KTiOPO4 (KTP) under 2.05 μm laser radiation, which is the highest among all of the metal selenites reported. It has also very simple chemical composition and can be synthesized easily under mild hydrothermal conditions...
August 3, 2016: Journal of the American Chemical Society
Niraj Kumar, Pawan Vasudeva, Anup Kumar, Harbinder Singh, Ashmika Sinha
BACKGROUND: To compare short-term efficacy and safety of channel photoselective vaporization of prostate (PVP) and channel transurethral resection of prostate (TURP) in patients with bladder outlet obstruction (BOO) secondary to advanced carcinoma prostate. METHODS: This prospective, non-randomized comparative study was conducted between April 2012 and December 2014. Patients with locally advanced/metastatic carcinoma prostate, who underwent either channel PVP or channel TURP for troublesome LUTS/ acute retention of urine were included in the study...
August 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Bo Hu, Zhenyu Song, Hui Liu, Liang Qiao, Yong Zhao, Muwen Wang, Wei Song, Dong Zhang, Xunbo Jin, Haiyang Zhang
Bladder neck contracture (BNC) after GreenLight laser photoselective vaporization (PVP) of benign prostatic hyperplasia is a common complication. In the present study, data of patients received 80 or 180 W PVP were collected. Perioperative parameters, including applied energy, irradiation time, catheter removal time, and hospital stay, were recorded. Postoperative parameters, including maximum urinary flow rate, International Prostate Symptom Score, post-void residual volume, and incidences of BNC, were recorded at 3 and 12 months after operations...
June 30, 2016: Lasers in Medical Science
Berna Solak, Bahar Sevimli Dikicier, Rabia Oztas Kara, Teoman Erdem
BACKGROUND AND OBJECTIVES: Superficial cutaneous vascular lesions (SCVL) are quite common. Several types of lasers have been used to treat these lesions; however, there are no dedicated treatment guidelines and few studies in the literature addressed their treatment. AIMS: In this paper we aimed to report our clinical experience with Potassium-titanyl phosphate KTP laser treatment on different types of facial SCVLs including telangiectasia, spider angioma and erythema...
June 28, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Kenny F Lin, Samuel Selesnick
OBJECTIVE: To evaluate hearing outcomes and incidence of sensorineural hearing loss (SNHL) after stapedotomy with adipose tissue seal, and to compare adipose tissue sealing with alternative techniques. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary referral center. PATIENTS: Primary stapedotomy was performed in 179 patients using a KTP laser, microdrill, piston prosthesis, and adipose tissue seal of the oval window fenestra between 1991 and 2015...
August 2016: Otology & Neurotology
Isabel N Figueiredo, Carlos Leal, Luís Pinto, Jason Bolito, André Lemos
Currently, a number of studies focus on the study and design of new healthcare technologies to improve elderly health and quality of life. Taking advantage of the popularity, portability, and inherent technology of smartphones, we present an emergency application for smartphones, designated as knock-to-panic (KTP). This innovative and novel system enables users to simply hit their devices in order to send an alarm signal to an emergency service. This application is a complete and autonomous emergency system, and can provide an economic, reliable, and unobtrusive method for elderly monitoring or safety protection...
September 2016: Medical Engineering & Physics
Juliana Perazzo, Mônica Lopes-Ferreira, Sónia Sá Santos, Isa Serrano, Antónia Pinto, Carla Lima, Eduard Bardaji, Isaura Tavares, Montserrat Heras, Katia Conceição, Miguel A R B Castanho
Kyotorphin (KTP) is an endogenous peptide with analgesic properties when administered into the central nervous system (CNS). Its amidated form (l-Tyr-l-Arg-NH2; KTP-NH2) has improved analgesic efficacy after systemic administration, suggesting blood-brain barrier (BBB) crossing. KTP-NH2 also has anti-inflammatory action impacting on microcirculation. In this work, selected derivatives of KTP-NH2 were synthesized to improve lipophilicity and resistance to enzymatic degradation while introducing only minor changes in the chemical structure: N-terminal methylation and/or use of d amino acid residues...
August 17, 2016: ACS Chemical Neuroscience
Kevin M Motz, Alexander T Hillel
This review will highlight the indications and benefits of office-based therapy for recurrent respiratory papillomatosis (RRP) and discuss the utilization of photo-dynamic lasers and adjuvant medical therapy in office-based settings. Office-based management of RRP allows for more timely interventions, is preferred by the majority of patients, and negates the risk of general anesthesia. Current literature argues for the utilization of KTP laser over CO2 laser for office-based treatment of RRP. Medical therapies for RRP are limited, but agents such as bevacizumab are promising and have been shown to reduce disease burden...
June 2016: Current Otorhinolaryngology Reports
Yun-Chen Huang, Steve Shinn-Forng Peng, Wei-Chung Hsu
OBJECTIVE: This study aims to assess the efficacy of a novel endoscopic management for congenital pyriform sinus fistula (CPSF) using potassium titanyl phosphate (KTP) laser assisted endoscopic tissue fibrin glue biocauterization in children. METHOD: From 2010 to 2014, a total of 5 children with recurrent or acute suppurative thyroiditis or neck abscess secondary to CPSF were enrolled retrospectively in this study. RESULTS: Mean age at the first time of endoscopic biocauterization was 6...
June 2016: International Journal of Pediatric Otorhinolaryngology
Ellen Greijmans, Hedwig Luiting-Welkenhuyzen, Harriet Luijks, H Jorn Bovenschen
BACKGROUND: Although not an accepted standard treatment, the 532-nm continuous wave potassium titanyl phosphate (CW-KTP) laser might be a powerful device to treat xanthelasma palpebrarum (XP). OBJECTIVE: To determine the safety and efficacy of CW-KTP laser treatment for XP. MATERIALS AND METHODS: Between January 2013 and January 2015, 30 consecutive patients with XP were treated with a 532-nm CW-KTP laser (spot size: 0.9 mm, power: 5.0 W, fluence: 36-38 J/cm, pulse width: 46 milliseconds, frequency: 2...
July 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Olusegun Famure, Heebah Sultan, Nicholas Phan, Michael Garrels, Lee-Anne Hyer, S Joseph Kim
The Kidney Transplant Program (KTP) at the Toronto General Hospital has taken great strides in preparing to meet the needs of patients and health care providers, as the number of end-stage renal disease patients in Ontario increases. The KTP has begun the process of increasing engagement and collaboration with various stakeholders from the pre- to the post-transplant phase through (1) the development of innovative programs to increase the number of live kidney donations, (2) the development and maintenance of information technology solutions that work simultaneously to provide data to manage and treat patients, and conduct research, and (3) the development, implementation, and delivery of educational presentations and tools to various stakeholders both at the referring centres and the transplant program...
January 2016: CANNT Journal, Journal ACITN
Akihito Ohnishi, Michio Senda, Tomohiko Yamane, Tomoko Mikami, Hiroyuki Nishida, Tomoyuki Nishio, Go Akamatsu, Yasuhiko Ikari, Shogo Kimoto, Kazuki Aita, Masahiro Sasaki, Hiroko Shinkawa, Yasuji Yamamoto, Miho Shukuri, Aya Mawatari, Hisashi Doi, Yasuyoshi Watanabe, Hirotaka Onoe
INTRODUCTION: Neuroinflammatory processes play an important role in the pathogenesis of Alzheimer's disease (AD). As a biomarker of neuroinflammatory processes, we designed (11)C-labeled ketoprofen methyl ester ([(11)C]KTP-Me) to increase the blood-brain barrier permeability of ketoprofen (KTP), a selective cyclooxygenase-1 (COX-1) inhibitor. Animal studies indicated that [(11)C]KTP-Me enters the brain and accumulates in activated microglia of inflammatory lesions. In a first-in-human study, we reported that [(11)C]KTP-Me is a safe positron emission tomography (PET) tracer and enters the brain; the radioactivity is washed out from normal cerebral tissue...
July 2016: Nuclear Medicine and Biology
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