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Faecal incontinence

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https://www.readbyqxmd.com/read/28481856/systematic-review-of-animal-models-used-in-research-of-origins-and-treatments-of-fecal-incontinence
#1
Judith Evers, James F X Jones, P Ronan O'Connell
BACKGROUND: Fecal incontinence is a common disorder, but its pathophysiology is not completely understood. OBJECTIVE: The aim of this review is to present animal models that have a place in the study of fecal incontinence. DATA SOURCES: A literature review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines performed in August 2016 revealed 50 articles of interest. Search terms included fecal/faecal incontinence and animal model or specific species...
June 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28477435/sacral-nerve-stimulation-can-be-an-effective-treatment-for-low-anterior-resection-syndrome
#2
Saleh M Eftaiha, Banujan Balachandran, Slawomir J Marecik, Anders Mellgren, Johan Nordenstam, George Melich, Leela M Prasad, John J Park
AIM: Sacral nerve stimulation has become a preferred method for the treatment of faecal incontinence in patients who fail conservative (non-operative) therapy. In previous small studies, sacral nerve stimulation has demonstrated improvement of faecal incontinence and quality of life in a majority of patients with low anterior resection syndrome. We evaluated the efficacy of sacral nerve stimulation in the treatment of low anterior resection syndrome, using a recently developed and validated low anterior resection syndrome instrument to quantify symptoms...
May 6, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28445798/episiotomy-what-angle-do-you-cut-to-the-midline
#3
Kenneth Ma, Louise Byrd
OBJECTIVE: Although episiotomies are the commonest obstetric procedure performed the technique of performing one varies amongst obstetricians and midwives. The angle of episiotomy to the midline in particular has been shown to influence the risk of developing obstetric anal sphincter injuries (OASIS). In order to identify the differences in technique and to identify targets for training we undertook a practice survey of episiotomies to analyse the differences in technique between grades of obstetricians and midwives...
April 11, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28436201/brain-responses-to-mechanical-rectal-stimuli-in-patients-with-faecal-incontinence-an-fmri-study
#4
Naseem Mirbagheri, Sean Hatton, Kheng-Seong Ng, Jim Lagopoulos, Marc A Gladman
AIM: Continence is dependent on anorectal/brain interactions. Consequently, aberrations of the brain-gut axis may be important in the pathophysiology of faecal incontinence (FI) in certain patients. The aim of this study was to assess the feasibility of recording brain responses to rectal mechanical stimuli in patients with FI using functional Magnetic Resonance Imaging (fMRI). METHOD: A prospective, cohort pilot study was performed to assess brain responses during rectal stimulation in 14 patients (4 male, mean [SD] age 62 [15] years)...
April 24, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28426476/autologous-myoblasts-for-the-treatment-of-fecal-incontinence-results-of-a-phase-2-randomized-placebo-controlled-study-mias
#5
Olivier Boyer, Valérie Bridoux, Camille Giverne, Aurélie Bisson, Edith Koning, Anne-Marie Leroi, Pascal Chambon, Justine Déhayes, Stephanie Le Corre, Serge Jacquot, Dominique Bastit, Jérémie Martinet, Estelle Houivet, Jean-Jacques Tuech, Jacques Benichou, Francis Michot
OBJECTIVE: The aim of this study was to evaluate the efficacy of intrasphincteric injections of autologous myoblasts (AMs) in fecal incontinence (FI) in a controlled study. SUMMARY OF BACKGROUND DATA: Adult stem cell therapy is expected to definitively cure FI by regenerating damaged sphincter. Preclinical data and results of open-label trials suggest that myoblast therapy may represent a noninvasive treatment option. METHODS: We conducted a phase 2 randomized, double-blind, placebo-controlled study of intrasphincteric injections of AM in 24 patients...
April 19, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28412947/report-of-the-first-clinical-case-of-intestinal-trichomoniasis-caused-by-tritrichomonas-foetus-in-a-cat-with-chronic-diarrhoea-in-brazil
#6
Aline S Hora, Samantha I Miyashiro, Fabiana C Cassiano, Paulo E Brandão, Archivaldo Reche-Junior, Hilda F J Pena
BACKGROUND: Tritrichomonas foetus is an emergent and important enteric pathogen of cats, which causes prolonged diarrhoea in cats. CASE PRESENTATION: This study describes a T. foetus infection in a seven-month-old, entire male domestic shorthair kitten with a six-month history of persistent large intestinal diarrhoea, faecal incontinence, prostration, apathy and weight loss. Parasites were microscopically observed and confirmed by PCR and DNA sequencing. Molecular analyses were carried out comparing the sequence obtained in this study with T...
April 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28378659/helping-people-to-live-better-with-and-beyond-bowel-cancer
#7
Claire Taylor
Do your patients ever worry about getting caught short? Does the fear of being faecally incontinent stop them from going to work or socialising?
April 5, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28371160/short-term-outcome-of-percutaneous-tibial-nerve-stimulation-for-low-anterior-resection-syndrome-results-of-a-pilot-study
#8
D F Altomare, A Picciariello, C Ferrara, R Digennaro, Y Ribas, M De Fazio
AIM: Percutaneous tibial nerve stimulation (PTNS) is a minimally invasive procedure, which has been demonstrated to be effective in faecal/urinary incontinence, but has never been tested in Low Anterior Resection Syndrome (LARS). The severity of LARS may be evaluated by the LARS-score, but rectal cancer treatments may also affect urinary and sexual function, which are not explored by the LARS-score. The TAPE-score is a new validated index addressing the overall pelvic-floor functions...
March 29, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28371010/laparoscopic-ventral-rectopexy-for-rectal-prolapse-and-rectal-intussusception-using-a-biological-mesh
#9
Sinan Albayati, Matthew J Morgan, Catherine E Turner
AIM: Laparoscopic ventral rectopexy (LVR) is a nerve sparing technique for the treatment of rectal prolapse. Concerns about the use of synthetic meshes in the pelvis and the associated risk of erosion have led to the recent use of biological meshes in some colorectal units. This retrospective study aims to assess the outcomes of patients undergoing LVR using a non-cross-linked non-dermal biological mesh. METHODS: Medical notes of all patients who underwent LVR between December 2011 and May 2014 were reviewed...
March 29, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28356133/abdominal-massage-for-neurogenic-bowel-dysfunction-in-people-with-multiple-sclerosis-amber-abdominal-massage-for-bowel-dysfunction-effectiveness-research-study-protocol-for-a-randomised-controlled-trial
#10
Doreen McClurg, Kirsteen Goodman, Suzanne Hagen, Fional Harris, Sean Treweek, Anton Emmanuel, Christine Norton, Maureen Coggrave, Selina Doran, John Norrie, Peter Donnan, Helen Mason, Sarkis Manoukian
BACKGROUND: Multiple sclerosis (MS) is a life-long condition primarily affecting younger adults. Neurogenic bowel dysfunction (NBD) occurs in 50-80% of these patients and is the term used to describe constipation and faecal incontinence, which often co-exist. Data from a pilot study suggested feasibility of using abdominal massage for the relief of constipation, but the effectiveness remains uncertain. METHODS/DESIGN: This is a multi-centred patient randomised superiority trial comparing an experimental strategy of once daily abdominal massage for 6 weeks against a control strategy of no massage in people with MS who have stated that their constipation is bothersome...
March 29, 2017: Trials
https://www.readbyqxmd.com/read/28346770/a-core-outcome-set-for-localised-prostate-cancer-effectiveness-trials
#11
Steven MacLennan, Paula R Williamson, Hanneke Bekema, Marion Campbell, Craig Ramsay, James N'Dow, Sara MacLennan, Luke Vale, Philipp Dahm, Nicolas Mottet, Thomas Lam
OBJECTIVE: To develop a core outcome set (COS) applicable for effectiveness trials of all interventions for localised prostate cancer. Many treatments exist for localised prostate cancer, although it is unclear which offers the optimal therapeutic ratio; which is confounded by inconsistencies in the selection, definition, measurement and reporting of outcomes in clinical trials. PATIENTS, SUBJECTS AND METHODS: A list of 79 outcomes was derived from a systematic review of published localised prostate cancer effectiveness studies and semi-structured interviews with 15 patients with prostate cancer patients...
March 27, 2017: BJU International
https://www.readbyqxmd.com/read/28319326/altered-defaecatory-behaviour-and-faecal-incontinence-in-a-video-tracked-animal-model-of-pudendal-neuropathy
#12
L A Devane, E Lucking, J Evers, M Buffini, S M Scott, C H Knowles, P R O'Connell, J F X Jones
AIM: The aim was to develop a behavioural animal model of faecal continence and assess the effect of retro-uterine balloon inflation (RBI) injury. RBI in the rat causes pudendal neuropathy, a risk factor for obstetric related faecal incontinence in humans. METHOD: Video-tracking of healthy rats (n = 12) in a cage containing a latrine box was used to monitor their defaecatory behaviour index (DBI) over 2 weeks. The DBI (range 0-1) was devised by dividing the defaecation rate (pellets per hour) outside the latrine by that of the whole cage...
May 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28304143/anal-function-after-endoluminal-loco-regional-resection-by-transanal-endoscopic-microsurgery-and-radiotherapy-for-rectal-cancer
#13
Ivano Biviano, Andrea Balla, Danilo Badiali, Silvia Quaresima, Giancarlo D'Ambrosio, Emanuele Lezoche, Enrico Corazziari, Alessandro M Paganini
AIM: In patients with rectal cancer, surgery and chemo-radiotherapy may affect the anal sphincter function. Few studies evaluated the ano-rectal function after neoadjuvant chemo-radiotherapy (n-CRT) and/or Transanal Endoscopic Microsurgery (TEM). The aim of this study was to evaluate the effects of n-CRT and TEM on ano-rectal function. METHOD: Thirty-seven patients with rectal cancer underwent ano-rectal manometry and Wexner score for faecal incontinence at baseline, after n-CRT (cT2-T3N0 cancer) and at 4 and 12 months after surgery...
March 17, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28299421/evaluation-of-sexual-dysfunction-in-female-patients-presenting-with-faecal-incontinence-or-defecation-disorder
#14
Gianluca Pellino, Lisa Ramage, Constantinos Simillis, Oliver Warren, Christos Kontovounisios, Emile Tan, Paris Tekkis
PURPOSE: Female patients with pelvic floor diseases may suffer from several sexual disorders and sexual life impairments. The aim of this manuscript was to evaluate sexual dysfunction in female patients presenting with faecal incontinence (FI) and defecation disorder (DD). METHODS: A retrospective review was performed of a prospectively collected database of sexually active women referred to the pelvic floor clinic, who completed the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-12 (PISQ-12) at first visit...
May 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28298708/outcomes-of-sacral-nerve-stimulation-for-faecal-incontinence-in-northern-ireland
#15
G W Irwin, B V Dasari, R Irwin, D Johnston, K Khosraviani
BACKGROUND: Sacral nerve root stimulation (SNS) is an effective and developing therapy for faecal incontinence, a debilitating condition that can result in social and personal incapacitation. OBJECTIVES: The objectives of this study are to assess the morbidity of the procedure, improvement in the incontinence scores and Quality of Life (QoL) following SNS. MATERIALS AND METHODS: Patients were identified from the Northern Ireland regional SNS service from 2006 to 2012...
January 2017: Ulster Medical Journal
https://www.readbyqxmd.com/read/28293791/pregnant-women-s-awareness-knowledge-and-beliefs-about-pelvic-floor-muscles-a-cross-sectional-survey
#16
Anne-Marie Hill, Steven M McPhail, Judith M Wilson, Richard G Berlach
INTRODUCTION AND HYPOTHESIS: Pregnant women benefit from completing pelvic floor muscle exercises (PFMEs). The aims of the study were to evaluate pregnant women's levels of awareness, knowledge, and beliefs about the pelvic floor muscles (PFMs) and PFMEs. METHODS: A cross-sectional survey was conducted. Respondents were pregnant women over the age of 18 years who attended antenatal clinics in Western Australia (WA). Questionnaire items measured awareness and knowledge about PFMs, confidence and beliefs about engaging in PFMEs, and attendance at antenatal education (ANE) classes...
March 14, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28290468/ageing-with-neurogenic-bowel-dysfunction
#17
S D Nielsen, P M Faaborg, N B Finnerup, P Christensen, K Krogh
STUDY DESIGN: Longitudinal study with postal survey. OBJECTIVES: To describe changes in the patterns of neurogenic bowel dysfunction and bowel management in a population of people with spinal cord injury (SCI) followed for two decades. SETTING: Members of the Danish SCI Association. METHODS: In 1996, a validated questionnaire on bowel function was sent to the members of the Danish SCI Association (n=589). The same questionnaire was sent to all the surviving members in 2006 (n=284) and in 2015 (n=178)...
March 14, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28252330/supporting-people-living-with-dementia-and-faecal-incontinence
#18
Bridget Russell, Marina Buswell, Christine Norton, Jo Rycroft Malone, Danielle Harari, Rowan Harwood, Brenda Roe, Mandy Fader, Vari M Drennan, Frances Bunn, Claire Goodman
No abstract text is available yet for this article.
March 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28230440/late-gastrointestinal-effects-of-pelvic-radiation-a-nurse-led-service
#19
Helen Ludlow, John Green, Jeff Turner
There are currently at least 2 million people in the UK living with and following a cancer diagnosis. Typically four out of every ten people with cancer will receive radiotherapy, but a large proportion of people who have pelvic radiotherapy may go on to develop gastrointestinal (GI) symptoms. This includes rectal bleeding and faecal incontinence, which can have a huge impact on quality of life. These problems often go under-reported by patients and are also under-recognised or under-treated by health professionals...
February 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28217378/role-of-clinical-pathway-in-improving-the-quality-of-care-for-patients-with-faecal-incontinence-a-randomised-trial
#20
Zeiad I Hussain, Michael Lim, Stevan Stojkovic
AIM: To assess the development and implementation of the Integrated Rapid Assessment and Treatment (IRAT) pathway for the management of patients with fecal incontinence and measure its impact on patients' care. METHODS: Patients referred to the colorectal unit in our hospital for the management of faecal incontinence were randomised to either the Standard Care pathway or the newly developed IRAT pathway in this feasibility study. The IRAT pathway is designed to provide a seamless multidisciplinary care to patients with faecal incontinence in a timely fashion...
February 6, 2017: World Journal of Gastrointestinal Pharmacology and Therapeutics
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