Jingyuan Wu, Tuoyu Zhou, Haofei Shen, Yanbiao Jiang, Qi Yang, Shaochen Su, Luming Wu, Xue Fan, Min Gao, Yang Wu, Yun Cheng, Yuan Qi, Ting Lei, Yongan Xin, Shiqiang Han, Xiangkai Li, Yiqing Wang
Bisphenol A (BPA), an environmental endocrine disruptor (EDC), has been implicated in impairing intestinal and male reproductive dysfunction. The efficacy of gut microbiota modulation for BPA-exposed testicular dysfunction has yet to be verified through research. Therefore, this study explored the potential of mixed probiotics in restoring spermatogenesis damage through the gut-testis axis under BPA exposure. We selected two probiotics strains (Lactobacillus rhamnosus and Lactobacillus plantarum) with BPA removal properties in vitro and the BPA-exposed male mice model was established...
January 2, 2024: Ecotoxicology and Environmental Safety