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Total mesorectal excision

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https://www.readbyqxmd.com/read/29340993/laparoscopic-assisted-modified-intersphincter-resection-for-ultralow-rectal-cancer
#1
Haiyang Zhou, Canping Ruan, Zhiguo Wang, Zhiqian Hu
BACKGROUND: Intersphincter resection (ISR) is considered to be a superior technique offering sphincter preservation in patients with ultralow rectal cancer.1 Because high-definition laparoscopy offers wider and clearer vision into the narrow pelvic cavity and intersphincteric space, ISR has been further refined.2 However, functional outcome after ISR has not been optimal. More than half of patients receiving ISR suffer partial or even complete anal incontinence.3 We therefore propose a laparoscopic-assisted modified ISR, with the aim of improving sphincter function following ISR...
January 16, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29337782/laparoscopic-rectovaginopexy-for-neorectal-prolapse-after-transanal-total-mesorectal-excision
#2
Joel Shapiro, Joris J J C de Graaf, Pascal G Doornebosch, Maarten Vermaas, Eelco J R de Graaf
No abstract text is available yet for this article.
February 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29329555/exercise-during-and-after-neoadjuvant-rectal-cancer-treatment-the-exert-trial-study-protocol-for-a-randomized-controlled-trial
#3
Andria R Morielli, Nawaid Usmani, Normand G Boulé, Diane Severin, Keith Tankel, Tirath Nijjar, Kurian Joseph, Alysa Fairchild, Kerry S Courneya
BACKGROUND: Standard treatment for locally advanced rectal cancer includes 5-6 weeks of neoadjuvant chemoradiotherapy (NACRT) followed by total mesorectal excision 6-8 weeks later. NACRT improves local disease control and surgical outcomes but also causes side effects including fatigue, diarrhea, hand-foot syndrome, and physical deconditioning that may impede quality of life (QoL), treatment completion, treatment response, and long-term prognosis. Interventions to improve treatment outcomes and manage side effects that are safe, tolerable and low-cost are highly desirable...
January 12, 2018: Trials
https://www.readbyqxmd.com/read/29316129/anastomotic-leakage-after-side-to-end-anastomosis-for-rectal-cancer-does-leakage-location-matter
#4
Elisabeth Hain, Léon Maggiori, Magaly Zappa, Justine Prost À la Denise, Yves Panis
AIM: To assess outcome according to location of anastomotic leakage (AL) after side-to-end stapler or manual low colorectal or coloanal anastomosis following laparoscopic total mesorectal excision (TME) for rectal cancer. METHODS: All patients presenting with symptomatic or asymptomatic AL after TME and side-to-end low anastomosis for rectal cancer performed from 2005 to 2014 were identified from our prospective database. CT-scans with contrast enema were reviewed to assess location of AL origin...
January 6, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29315090/incidence-and-risk-factors-for-anastomotic-failure-in-1594-patients-treated-by-transanal-total-mesorectal-excision-results-from-the-international-tatme-registry
#5
Marta Penna, Roel Hompes, Steve Arnold, Greg Wynn, Ralph Austin, Janindra Warusavitarne, Brendan Moran, George B Hanna, Neil J Mortensen, Paris P Tekkis
OBJECTIVE: To determine the incidence of anastomotic-related morbidity following Transanal Total Mesorectal Excision (TaTME) and identify independent risk factors for failure. BACKGROUND: Anastomotic leak and its sequelae are dreaded complications following gastrointestinal surgery. TaTME is a recent technique for rectal resection, which includes novel anastomotic techniques. METHODS: Prospective study of consecutive reconstructed TaTME cases recorded over 30 months in 107 surgical centers across 29 countries...
January 5, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29313396/the-role-of-tamis-transanal-minimally-invasive-surgery-in-the-management-of-advanced-rectal-cancer-one-shared-story-of-three-exceptional-cases
#6
Dimitrios Giannoulopoulos, Constantinos Nastos, Maria Gavriatopoulou, Antonios Vezakis, Dionysios Dellaportas, Ira Sotirova, Georgios Giokas, Georgios Polymeneas, Theodosios Theodosopoulos
PURPOSE OF THE STUDY: The current gold standard for contemporary treatment of rectal cancer is total mesorectal excision (TME), achieving excellent local disease control and low recurrence rates. However, TME may be associated with postoperative mortality and quality of life deterioration. Therefore, the need to develop less radical treatment strategies has emerged. Transanal minimally invasive surgery (TAMIS) is currently indicated only for early rectal cancer. However, local excision following chemoradiation has yielded promising clinical outcomes in selected cases with more advanced disease...
January 9, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29288190/can-we-save-the-rectum-by-watchful-waiting-or-transanal-microsurgery-following-chemo-radiotherapy-versus-total-mesorectal-excision-for-early-rectal-cancer-star-trec-study-protocol-for-a-multicentre-randomised-feasibility-study
#7
Anouk J M Rombouts, Issam Al-Najami, Natalie L Abbott, Ane Appelt, Gunnar Baatrup, Simon Bach, Aneel Bhangu, Karen-Lise Garm Spindler, Richard Gray, Kelly Handley, Manjinder Kaur, Ellen Kerkhof, Camilla Jensenius Kronborg, Laura Magill, Corrie A M Marijnen, Iris D Nagtegaal, Lars Nyvang, Femke P Peters, Per Pfeiffer, Cornelis Punt, Philip Quirke, David Sebag-Montefiore, Mark Teo, Nick West, Johannes H W de Wilt
INTRODUCTION: Total mesorectal excision (TME) is the highly effective standard treatment for rectal cancer but is associated with significant morbidity and may be overtreatment for low-risk cancers. This study is designed to determine the feasibility of international recruitment in a study comparing organ-saving approaches versus standard TME surgery. METHODS AND ANALYSIS: STAR-TREC trial is a multicentre international randomised, three-arm parallel, phase II feasibility study in patients with biopsy-proven adenocarcinoma of the rectum...
December 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29280120/-clinical-application-of-compound-anastomotic-device-in-protective-terminal-ileostomy-during-rectal-cancer-operation
#8
Qi Huang, Feng Cao, Jinzhe Zhou, Liming Liu, Bujun Ge
OBJECTIVE: To investigate the clinical effect of the application of "compound anastomotic device" on the high-risk colorectal anastomosis in rectal cancer patients undergoing protective ileostomy. METHODS: A total of 116 rectal cancer patients undergoing surgical procedure and prophylactic ileostomy in Tongji Hospital (90 cases) and The Third People's Hospital of Jingdezhen City (26 cases) from May 2011 to October 2016 were prospectively enrolled in the study. Paralleled control study and random digital table were applied...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29275912/advances-in-organ-preserving-strategies-in-rectal-cancer-patients
#9
REVIEW
Rutger C H Stijns, Mike-Stephen R Tromp, Niek Hugen, Johannes H W de Wilt
Treatment of rectal cancer patients has been subjected to change over the past thirty years. Total mesorectal excision is considered the cornerstone of rectal cancer treatment, but is also associated with significant morbidity resulting in an impaired quality of life. The addition of neoadjuvant chemoradiotherapy to surgery has shown to improve survival and local control and may lead to a partial or even complete response (CR). This raises questions regarding the necessity for subsequent radical surgery. After careful patient selection local excision and wait-and-see approaches are explored, aiming to improve quality of life without compromising oncological outcome...
December 12, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29249592/robotic-low-anterior-resection-versus-transanal-total-mesorectal-excision-in-rectal-cancer-a-comparison-of-115-cases
#10
Daniel Perez, Nathaniel Melling, Matthias Biebl, Matthias Reeh, Julia-Kristin Baukloh, Jameel Miro, Adam Polonski, Jakob R Izbicki, Belinda Knoll, Johann Pratschke, Felix Aigner
BACKGROUND: Robotic low anterior resection (RLAR) and transanal total mesorectal excision (TaTME) are novel surgical techniques for resection of rectal cancer. To our knowledge, no data exist on direct comparison of these procedures in terms of oncological or functional parameters. METHODS: 60 RLAR and 55 TaTME for rectal cancer were compared in respect to patient characteristics, clinicopathological parameters, intraoperative and perioperative results and anatomopathological outcome...
November 26, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29234940/st-gallen-consensus-on-safe-implementation-of-transanal-total-mesorectal-excision
#11
Michel Adamina, Nicolas C Buchs, Marta Penna, Roel Hompes
BACKGROUND: The management of rectal cancer has evolved over the years, including the recent rise of Transanal Total Mesorectal Excision (TaTME). TaTME addresses the limitations created by the bony confines of the pelvis, bulky tumours, and fatty mesorectum, particularly for low rectal cancers. However, guidance is required to ensure safe implementation and to avoid the pitfalls and potential major morbidity encountered by the early adopters of TaTME. We report a broad international consensus statement, which provides a basis for optimal clinical practice...
December 12, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29234923/non-inferiority-multicenter-prospective-randomized-controlled-study-of-rectal-cancer-t2-t3s-superficial-n0-m0-undergoing-neoadjuvant-treatment-and-local-excision-tem-vs-total-mesorectal-excision-tme
#12
X Serra-Aracil, C Pericay, T Golda, L Mora, E Targarona, S Delgado, A Reina, F Vallribera, J M Enriquez-Navascues, S Serra-Pla, J C Garcia-Pacheco
PURPOSE: The standard treatment of rectal adenocarcinoma is total mesorectal excision (TME), in many cases requires a temporary or permanent stoma. TME is associated with high morbidity and genitourinary alterations. Transanal endoscopic microsurgery (TEM) allows access to tumors up to 20 cm from the anal verge, achieves minimal postoperative morbidity and mortality rates, and does not require an ostomy. The treatment of T2, N0, and M0 cancers remains controversial. Preoperative chemoradiotherapy (CRT) in association with TEM reduces local recurrence and increases survival...
December 12, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29221180/pelvic-recurrence-after-definitive-surgery-for-locally-advanced-rectal-cancer-a-retrospective-investigation-of-implications-for-precision-radiotherapy-field-design
#13
Chao Li, Yinju Zhu, Tong Tong, Ye Xu, Yun Guan, Jingwen Wang, Huankun Wang, Ji Zhu
Background: To analyze the local distribution of pelvic recurrence after total mesorectal excision, with a view to simplifying the formulation of optimal individualized radiotherapy plans. Methods: We retrospectively investigated the data of 168 patients diagnosed with recurrent pelvic cancer treated at Fudan University Shanghai Cancer Center between January 2008 and December 2012. The following were collected depending on availability: operative report, histological report, specimen photographs, initial preoperative images, images confirming local recurrence, and clinical history...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29217973/hybrid-transanal-and-total-mesorectal-excision-after-transanal-endoscopic-microsurgery-for-unfavourable-early-rectal-cancer-a-report-of-two-cases
#14
Narimantas E Samalavičius, Audrius Dulskas, Kęstutis Petrulis, Alfredas Kilius, Renatas Tikuišis, Raimundas Lunevičius
Completion total mesorectal excision (TME) is a rare but complex procedure after transanal endoscopic microsurgery for early rectal cancer with unfavourable final histology. Two cases are reported when completion TME was performed after upfront transanal partial mesorectal dissection. Intact non-perforated TME specimens with negative and adequate distal and circumferential margins were created. The quality of both total mesorectal excisions was complete and distal margins were sufficient. We believe that our technique might be a way of approaching completion TME after TEM, especially in cases of low rectal cancer...
2017: Acta Medica Lituanica
https://www.readbyqxmd.com/read/29208050/robotic-assisted-total-mesorectal-excision-with-the-single-docking-technique-for-patients-with-rectal-cancer
#15
Ching-Wen Huang, Hsiang-Lin Tsai, Yung-Sung Yeh, Wei-Chih Su, Ming-Yii Huang, Chun-Ming Huang, Yu-Tang Chang, Jaw-Yuan Wang
BACKGROUND: The robotic system has advantages of high-definition three-dimensional vision and articular instruments with high dexterity, allowing more precise dissection in the deep and narrow pelvic cavity. METHODS: We enrolled 95 patients with stage I-III rectal cancer (adenocarcinoma) who underwent totally robotic-assisted total mesorectal excision (TME) with single-docking technique at a single institution between September 2013 and December 2016. RESULTS: Of the 95 patients, 48 (50...
December 5, 2017: BMC Surgery
https://www.readbyqxmd.com/read/29205769/highly-dexterous-2-module-soft-robot-for-intra-organ-navigation-in-minimally-invasive-surgery
#16
Haider Abidi, Giada Gerboni, Margherita Brancadoro, Alessandro Diodato, Matteo Cianchetti, Helge Wurdemann, Kaspar Althoefer, Arianna Menciassi
BACKGROUND: For some surgical interventions, like the Total Mesorectal Excision (TME), traditional laparoscopes lack the flexibility to safely maneuver and reach difficult surgical targets. This paper answers this need through designing, fabricating and modelling a highly dexterous 2-module soft robot for minimally invasive surgery (MIS). METHODS: A soft robotic approach is proposed that uses flexible fluidic actuators (FFAs) allowing highly dexterous and inherently safe navigation...
December 5, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29205758/transanal-endoscopic-microsurgery-a-new-zealand-experience
#17
Ian Bloomfield, Roelof Van Dalen, Simione Lolohea, Linus Wu
BACKGROUND: Transanal endoscopic microsurgery (TEMS) is a proven alternative therapy to either radical surgery or endoscopic mucosal resection for rectal neoplasms. It has proven benefits with lower morbidity and mortality compared with total mesorectal excision, and a lower local recurrence rate when compared to endoscopic mucosal techniques. METHODS: A retrospective data collection of TEMS procedures performed through Waikato District Health Board, New Zealand, from 2010 to 2015 was conducted...
December 3, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29203980/quality-of-life-after-total-mesorectal-excision-tme-for-rectal-carcinoma-a-study-from-a-tertiary-care-hospital-in-northern-india
#18
Rauf Ahmad Wani, Ikhlaq-Ul-Aziz Bhat, Fazl Qadir Parray, Nisar Ahmad Chowdri
Quality of life (QoL) is a key element in rectal cancer (RC) patients. There is not much data regarding this from North India. This study assesses QoL following low anterior resection (LAR) and abdominoperineal resection (APR), operated for low rectal tumors at a high-volume center in northern India. One-hundred-thirty patients of rectal carcinoma were prospectively assessed for quality of life using the European Organization for Cancer QLQ-30 and CR29 questionnaires and compared with reference data population...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29198494/distribution-of-metastases-in-mesorectum-is-unpredictable-metastases-do-not-respect-tumor-localization-even-in-small-non-circumferential-rectal-cancers
#19
Magdaléna Linter Kapišinská, Eva Hovorková, Veronika Závalová, Zdeněk Šubrt, Martin Kuneš, Alexander Ferko
INTRODUCTION: Low anterior resection with total mesorectal excision (TME) is the gold standard for surgical treatment of rectal carcinoma. The radicality of this procedure is negatively counterbalanced by morbidity, lethality, and numerous other complications. Local excision would appear to be an attractive alternative, but its radicality is disputable due to risk of undetected metastasis to the mesorectum. The study aimed to determine the location of mesorectal metastases with respect to circumferentially - located tumors in patients with tumors involving less than one-third of the rectal circumference...
January 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29190178/transanal-total-mesorectal-excision-in-lower-rectal-cancer-comparison-of-short-term-outcomes-with-conventional-laparoscopic-total-mesorectal-excision
#20
Tung-Cheng Chang, Kee-Thai Kiu
BACKGROUND: Transanal total mesorectal excision (TaTME) is a novel technique to treat rectal cancer and also to obtain good-quality specimens. This study investigated the clinical results and perioperative and pathological outcomes of TaTME in lower rectal cancer treatment in comparison with laparoscopic total mesorectal excision (LaTME). METHODS: During January 2014 to May 2017, all consecutive patients with lower rectal cancer who underwent TaTME were identified...
November 30, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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