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Gastric cancer laparoscopy

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https://www.readbyqxmd.com/read/28431531/short-term-surgical-outcomes-of-laparoscopy-assisted-versus-totally-laparoscopic-billroth-ii-gastrectomy-for-gastric-cancer-a-matched-cohort-study
#1
Ji-Hyun Kim, Kyong-Hwa Jun, Hyung-Min Chin
BACKGROUND: To evaluate feasibility and benefits of intracorporeal anastomosis, we compared short-term surgical outcomes between laparoscopy-assisted distal gastrectomy (LADG) and totally laparoscopic distal gastrectomy (TLDG) with Billroth-II (B-II) anastomosis for gastric cancer. METHODS: Sixty patients underwent attempted B-II TLDG from 2011 through 2013. Patients who underwent B-II LADG prior to 2011 were matched to TLDG cases for demographics, comorbidities, tumor characteristics, and TNM stage...
April 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28430584/short-and-long-term-outcomes-of-laparoscopy-assisted-versus-open-total-gastrectomy-for-gastric-cancer-a-propensity-score-matched-analysis
#2
Jian-Xian Lin, Ju-Li Lin, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Chang-Ming Huang
BACKGROUND: Few studies have been designed to evaluate the short- and long-term outcomes of laparoscopy-assisted total gastrectomy (LATG), and a retrospective study of a large patient cohort is valuable before conducting randomized controlled clinical trials. RESULTS: Among all patients, age, tumor location, histologic type, pT stage, pN stage and pTNM stage significantly differed between the LATG group and OTG group. After the propensity score matching, the clinicopathological characteristics did not significantly differ between groups...
April 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415645/peritoneal-carcinomatosis-limits-of-diagnosis-and-the-case-for-liquid-biopsy
#3
REVIEW
James R W McMullen, Matthew Selleck, Nathan R Wall, Maheswari Senthil
Peritoneal Carcinomatosis (PC) is a late stage manifestation of several gastrointestinal malignancies including appendiceal, colorectal, and gastric cancer. In PC, tumors metastasize to and deposit on the peritoneal surface and often leave patients with only palliative treatment options. For colorectal PC, median survival is approximately five months, and palliative systemic therapy is able to extend this to approximately 12 months. However, cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) with a curative intent is possible in some patients with limited tumor burden...
March 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28378081/laparoscopy-assisted-distal-gastrectomy-is-feasible-also-for-elderly-patients-aged-80-years-and-over-effectiveness-and-long-term-prognosis
#4
Motohira Yoshida, Shigehiro Koga, Kei Ishimaru, Yuji Yamamoto, Yusuke Matsuno, Satoshi Akita, Jun Kuwabara, Kazufumi Tanigawa, Yuji Watanabe
BACKGROUND: Elderly patients usually have concurrent ailments, and the safety and effectiveness of laparoscopy-assisted distal gastrectomy (LADG) for these patients have been controversial. This study aimed to evaluate whether laparoscopy-assisted distal gastrectomy is safe and effective for elderly patients aged 80 years and over, as well as to clarify their long-term prognosis. METHODS: A total of 31 patients aged 80 years and over who underwent LADG in our hospital were retrospectively reviewed...
April 4, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28373179/dual-incarcerated-internal-hernias-after-laparoscopic-total-gastrectomy-with-roux-en-y-reconstruction-for-gastric-cancer
#5
Zi Qin Ng, Willy Low, Pradeep Subramanian, Joel Stein
Internal hernia postgastrectomy is an exceedingly rare complication especially in the laparoscopic cohort of patients. Different types of internal hernias have been described, of which, Petersen's and jejunojejunostomy mesenteric defect hernias are the most commonly encountered followed by oesophageal defect and transverse colon mesocolic defect hernias. As the early presentation is always non-specific, late diagnosis of internal hernia has significant implication on morbidity and mortality. Here, we present a rare case of a patient with previous laparoscopy-assisted total gastrectomy presented with features of impending bowel obstruction and bowel ischaemia secondary to dual incarcerated internal hernias...
April 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28365946/a-propensity-score-matching-analysis-comparing-the-oncological-outcomes-of-laparoscopic-and-open-gastrectomy-in-patients-with-gastric-carcinoma
#6
Youfang Gong, Baochun Wang, Haiyang Wang
PURPOSE: To compare the oncological outcomes of patients with laparoscopy-assisted gastrectomy with those with open resection to remove nonmetastatic gastric cancer. METHODS: A total of 532 patients were initially enrolled. Propensity score matching was applied to assemble a study cohort. The primary objective was overall survival (OS). Cancer-specific survival (CSS) and disease-free survival (DFS) were secondary objectives. RESULTS: A total of 388 patients were matched for analysis...
January 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28332353/port-site-metastases-and-chimney-effect-of-b-ultrasound-guided-and-laparoscopically-assisted-hyperthermic-intraperitoneal-perfusion-chemotherapy
#7
Ming Chen Ba, Hui Long, Xiang Liang Zhang, Yuan Feng Gong, Zhao Fei Yan, Shuai Wang, Yun Qiang Tang, Shu Zhong Cui
PURPOSE: CO₂ leakage along the trocar (chimney effect) has been proposed to be an important factor underlying port-site metastasis after laparoscopic surgery. This study aimed to test this hypothesis by comparing the incidence of port-site metastasis between B-ultrasound-guided and laparoscopically-assisted hyperthermic intraperitoneal perfusion chemotherapy (HIPPC). MATERIALS AND METHODS: Sixty-two patients with malignant ascites induced by gastrointestinal or ovarian cancer were divided into two groups to receive either B-ultrasound-guided or laparoscopically-assisted HIPPC...
May 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28331173/laparoscopic-gastrectomy-with-enhanced-recovery-after-surgery-protocol-single-center-experience
#8
Magdalena Pisarska, Michał Pędziwiatr, Piotr Major, Michał Kisielewski, Marcin Migaczewski, Mateusz Rubinkiewicz, Piotr Budzyński, Krzysztof Przęczek, Anna Zub-Pokrowiecka, Andrzej Budzyński
BACKGROUND Surgery remains the mainstay of gastric cancer treatment. It is, however, associated with a relatively high risk of perioperative complications. The use of laparoscopy and the Enhanced Recovery After Surgery (ERAS) protocol allows clinicians to limit surgically induced trauma, thus improving recovery and reducing the number of complications. The aim of the study is to present clinical outcomes of patients with gastric cancer undergoing laparoscopic gastrectomy combined with the ERAS protocol. MATERIAL AND METHODS Fifty-three (21 female/32 male) patients who underwent elective laparoscopic total gastrectomy due to cancer were prospectively analyzed...
March 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28314905/comparison-of-two-and-three-dimensional-display-for-performance-of-laparoscopic-total-gastrectomy-for-gastric-cancer
#9
Shingo Kanaji, Satoshi Suzuki, Hitoshi Harada, Masayasu Nishi, Masashi Yamamoto, Takeru Matsuda, Taro Oshikiri, Tetsu Nakamura, Yasuhiro Fujino, Masahiro Tominaga, Yoshihiro Kakeji
PURPOSE: Introduction of three-dimensional (3D) display might remove technical obstacles of laparoscopic surgery and improve laparoscopic skills. We analyzed the effect of 3D technology on operative performance during laparoscopic total gastrectomy (LTG) for gastric cancer and assessed its advantages over two-dimensional (2D) laparoscopy. METHODS: This study included 30 consecutive surgeries of LTG with esophagojejunostomy by the overlap method performed (3D group, n = 15, 2D group, n = 15)...
March 17, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28299807/evolving-application-of-minimally-invasive-cancer-operations-at-a-tertiary-cancer-center
#10
Luke V Selby, Ronald P DeMatteo, Renee M Tholey, William R Jarnagin, Julio Garcia-Aguilar, Paul D Strombom, Peter J Allen, T Peter Kingham, Martin R Weiser, Murray F Brennan, Vivian E Strong
BACKGROUND: Patients and providers are increasingly interested in the utilization, safety, and efficacy of minimally invasive surgery (MIS). We reviewed 11 years of MIS resections (laparoscopic and robotic) for intra-abdominal malignancies. METHODS: Patients who underwent gastrectomy, distal pancreatectomy, hepatic resection, and colorectal resection between 2004 and 2014 were identified. Cases were categorized as open, laparoscopic, and robotic based on the initial operation approach...
March 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28251018/changing-trends-in-gastric-cancer-surgery
#11
REVIEW
İlter Özer, Erdal Birol Bostancı, Murat Ulaş, Yusuf Özoğul, Musa Akoğlu
Gastric cancer is one of the most common causes of cancer-related death. It requires multimodal treatment and surgery is the most effective treatment modality. Radical surgery includes total or subtotal gastrectomy with lymph node dissection. The extent of lymphadenectomy still remains controversial. Eastern surgeons have performed D2 or more extended lymphadenectomy while their Western colleagues have performed more limited lymph node dissection. However, the trend has been changing in favour of D2 lymph node dissection in both hemispheres...
January 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28226356/-application-of-clockwise-modularized-lymphadenectomy-in-laparoscopic-gastrectomy-for-gastric-cancer
#12
Jiankun Hu, Kun Yang, Xinzu Chen, Weihan Zhang, Kai Liu, Xiaolong Chen, Linyong Zhao, Zongguang Zhou
OBJECTIVE: To investigate the feasibility and efficacy of clockwise modularized lymphadenectomy in laparoscopic gastrectomy for gastric cancer. METHODS: Clinical data of 19 cases who underwent the laparoscopic clockwise modularized lymphadenectomy for gastric cancer (clockwise group) from July 2016 to September 2016 were analyzed retrospectively. The clockwise modularized lymphadenectomy included the fixed operative order, detailed procedure and requirement of lymphadenectomy, which mainly reflected in assisting the exposure of operative field and dissection of lymph nodes through suspending the liver and banding the greater omentum, as well as proposing the requirements and attentions for the dissections of each station of lymph nodes to facilitate the quality control of lymphadenectomy...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226355/-role-of-diagnostic-laparoscopy-in-the-treatment-plan-of-gastric-cancer
#13
Haojie Li, Qi Zhang, Ling Chen, Lingqiang Min, Xuefei Wang, Fenglin Liu, Yihong Sun
OBJECTIVE: To assess the clinical value of the diagnostic laparoscopy in choosing treatment strategies for patients with gastric cancer. METHODS: Retrospective analysis was performed on clinical and pathological data collected from 2 023 patients undergoing gastric cancer surgery in the Zhongshan Hospital of Fudan University from 2009 to 2014. All the patients were diagnosed as gastric cancer by endoscopic biopsy and staged by imaging examination before surgery...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28226349/-prevention-and-treatment-of-complications-related-to-the-digestive-tract-reconstruction-in-laparoscopic-gastric-cancer-surgery
#14
Junsheng Peng, Shi Chen
With the development of laparoscopic techniques and equipments, laparoscopic-assisted, even total laparoscopic radical surgery for gastric cancer can be performed successfully. However, the incidence of postoperative complications is higher in the laparoscopy group as compared to the open-surgery group, which is still the barrier for the total laparoscopic radical gastrectomy. Similar to open surgery, the major complications of digestive tract reconstruction after laparoscopic radical gastrectomy are anastomotic leakage, anastomotic bleeding, anastomotic stricture and stenosis of input or output loop...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28194592/the-yield-of-staging-laparoscopy-in-gastric-cancer-is-affected-by-racial-and-ethnic-differences-in-disease-presentation
#15
Ibrahim Nassour, Hannah Fullington, Linda S Hynan, Adam C Yopp, Mathew M Augustine, Patricio M Polanco, Michael A Choti, John C Mansour, Sam C Wang, Matthew R Porembka
BACKGROUND: Gastric cancer is a heterogeneous disease with variable presentation between racial and ethnic groups. Staging laparoscopy (SL) detects occult metastases not visible on cross-sectional imaging and therefore improves staging. It remains unclear how differences in race and ethnicity affect disease presentation and the yield of SL. METHODS: We performed a retrospective review of a prospectively maintained database to identify patients with gastric cancer treated with curative intent at our institutions from 2008 to 2015...
February 13, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28187041/laparoscopy-assisted-versus-open-d2-distal-gastrectomy-for-advanced-gastric-cancer-results-from-a-randomized-phase-ii-multicenter-clinical-trial-coact-1001
#16
Young Kyu Park, Hong Man Yoon, Young-Woo Kim, Ji Yeon Park, Keun Won Ryu, Young-Joon Lee, Oh Jeong, Ki Young Yoon, Jun Ho Lee, Sang Eok Lee, Wansik Yu, Sang-Ho Jeong, Taebong Kim, Sohee Kim, Byoung-Ho Nam
OBJECTIVE: This randomized, phase II, multicenter clinical trial was conducted to evaluate the feasibility of laparoscopy-assisted distal gastrectomy (LADG) with D2 lymph node dissection compared with open distal gastrectomy (ODG) for the treatment of advanced gastric cancer (AGC). SUMMARY OF BACKGROUND DATA: D2 lymph node dissection has been accepted as standard treatment for AGC. Although LADG is widely performed in early gastric cancer (EGC), the feasibility of LADG in AGC has not been proven yet...
March 15, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28163200/comparative-study-of-laparoscopy-assisted-and-open-radical-gastrectomy-for-stage-t4a-gastric-cancer
#17
Fan Zhang, Yuanzhi Lan, Bo Tang, Yingxue Hao, Yan Shi, Peiwu Yu
BACKGROUND: The feasibility and safety of laparoscopic-assisted gastrectomy as a first-line treatment for advanced gastric cancer is controversial, especially for patients with serous membrane invasion. This study was designed to evaluate and compare the clinical effect of laparoscopy-assisted and open radical gastrectomy for stage T4a gastric cancer. MATERIALS AND METHODS: We performed a retrospective analysis of the clinical data of 230 patients with stage T4a gastric cancer in our hospital from October 2006 to October 2008...
February 3, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28133336/-a-case-of-an-elderly-patient-with-unresectable-gastric-cancer-treated-by-paclitaxel-and-ramucirumab
#18
Yutaka Kimura, Yoichi Makari, Johta Mikami, Junpei Yoshimura, Toshiya Inoue, Genta Sawada, Shin Nakahira, Jun Yamamura, Shunji Kamigaki, Ken Nakata, Tameyoshi Yamamoto, Naoki Ikeda, Masaki Tsujie, Junya Fujita, Hiroki Ohzato
An 80-year-old man was admitted to our hospital with appetite loss in December 2014. Gastroduodenal scope, abdominal computed tomography(CT), and laparoscopy revealed type 4 advanced gastric cancer(poorly differentiated adenocarcinoma) with multiple lymph node(LN)involvement and multiple peritoneal metastasis. S-1(80mg/body)was administrated between January 2015 and September 2015 in the outpatient clinic. A partial response was obtained, but a gastric tumor, ascites, and LN re-growth were observed. Since October 2015, paclitaxel(PTX)(70mg/m2; day 1, 8, and 15)and ramucir- umab(RAM)(8mg/kg; day 1 and 15)have been administered...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133325/-a-patient-with-stage-iv-gastric-cancer-who-survived-more-than-five-years-after-gastrectomy
#19
Ayumi Takaoka, Shinsuke Usui, Yuuichi Kumaki, Tomohiro Akutsu, Hiroko Matsunaga, Masaki Tashiro, Kaida Arita, Shigeo Haruki, Koji Ito, Akiyo Matsumoto, Noriaki Takiguchi
The prognosis of patients with Stage IV gastric cancer is generally poor. The 5-year overall survival rate is less than 10%. The patient was a 73-year-old man with Stage IV gastric cancer. Before chemotherapy, peritoneal dissemination was observed using staging laparoscopy. The patient received first-line chemotherapy with TS-1 plus CDDP. Renal function worsened and consequently the therapy was stopped. He received 3 courses of chemotherapy with weekly PTX. The peritoneal dissemination had disappeared by the second staging laparoscopy and he underwent distal gastrectomy...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133061/-curative-resection-for-chemorefractory-advanced-gastric-cancer-with-pancreatic-invasion-by-pancreatoduodenectomy-a-case-report
#20
Masahiro Koh, Kentaro Kishi, Ryo Tsukada, Masahiro Tanemura, Mitsuyoshi Tei, Toru Masuzawa, Yozo Suzuki, Kenta Furukawa, Mikako Ikehara, Hiroki Akamatsu
A 37-year-old woman was diagnosed with advanced gastric cancer. Pancreatic invasion of the tumor and positive cytology from peritoneal washing was found on staging laparoscopy. The patient received chemotherapy consisting of S-1 and CDDP, but the tumor size increased after 5 courses. The patient then received 2 courses of second line chemotherapy consisting of biweekly CPT-11; however, the tumor progressed and caused stenosis of the stomach. After gastrojejunostomy for the stenosis, negative cytology of intraperitoneal lavage was found...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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