keyword
MENU ▼
Read by QxMD icon Read
search

metaanalysis

keyword
https://www.readbyqxmd.com/read/29914277/the-fetal-fibronectin-test-25-years-after-its-development-what-is-the-evidence-regarding-its-clinical-utility-a-systematic-review-and-meta-analysis
#1
Gilles Faron, Lisa Balepa, José Parra, Jean-François Fils, Leonardo Gucciardo
BACKGROUND: The identification of women at risk for preterm birth should allow interventions which could improve neonatal outcome. Fetal fibronectin, a glycoprotein which acts normally as glue between decidua and amniotic membranes could be a good marker of impending labour when its concentration in cervicovaginal secretions between 22 and 36 weeks of gestation is ≥ 50 ng/mL. Many authors worldwide have tested this marker with many different methodologies and clinical settings, but conclusions about its clinical use are mixed...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29858239/rheumatoid-arthritis-and-risk-of-sexual-dysfunction-a-systematic-review-and-metaanalysis
#2
Shankun Zhao, Ermao Li, Jiamin Wang, Lianmin Luo, Jintai Luo, Zhigang Zhao
OBJECTIVE: It has been reported that there is an association between rheumatoid arthritis (RA) and increased susceptibility to sexual dysfunction (SD). This systematic review and metaanalysis aimed to investigate whether RA was a risk factor for SD. METHODS: MEDLINE (PubMed), EMBASE, and the Cochrane Library were systematically searched for all studies assessing sexual function in patients with RA. The association between RA and risk of SD was summarized using relative risk (RR) with 95% CI...
June 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29776450/the-role-of-surgical-margins-in-atypical-lipomatous-tumours-of-the-extremities
#3
Jessica Rauh, Alexander Klein, Andrea Baur-Melnyk, Thomas Knösel, Lars Lindner, Falk Roeder, Volkmar Jansson, Hans Roland Dürr
BACKGROUND: Atypical lipomatous tumours (ALT) are common adipocytic tumours. Due to their large size and deep-seated location, wide resection might result in severe functional deficits. The question which margins should be aimed is hence discussed controversially. METHODS: Forty consecutive patients underwent limb-sparing resections. Margins were defined as R0 (wide resection), R1 (marginal resection) or R2 if tumour was left. All patients were followed for evidence of local recurrence or remote metastases...
May 17, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29772543/functional-diagnostics-for-thyrotropin-hormone-receptor-autoantibodies-bioassays-prevail-over-binding-assays
#4
Simon David Lytton, Anke Schluter, Paul J Banga
Autoantibodies to the thyrotropin hormone receptor (TSH-R) are directly responsible for the hyperthyroidism in Graves' disease and mediate orbital manifestations in Graves' orbitopathy (otherwise known as thyroid eye disease). These autoantibodies are heterogeneous in their function and collectively referred to as TRAbs. Measurement of TRAbs is clinically important for diagnosis of a variety of conditions and different commercial assays with high sensitivity and specificity are available for diagnostic purposes...
June 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/29737822/effects-of-mthfr-a1298c-polymorphism-on-peripheral-blood-folate-concentration-in-healthy-populations-a-meta-analysis-of-observational-studies
#5
Yu Xin, Lihua Wu, Xiaolin Lu, Shaofang Shangguan, Zhen Wang, Shaoyan Chang, Jiyong Yin, Wei Piao, Ting Zhang, Li Wang
BACKGROUND AND OBJECTIVES: Methylenetetrahydrofolate reductase (MTHFR) irreversibly converts 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, which is the main form of folate used in the body. Previous studies suggest that MTHFR polymorphism influences folate metabolism, but conflicting results are reported. We performed a meta-analysis to accurately characterize the association between MTHFR A1298C polymorphism and peripheral blood folate concentration in healthy populations...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29735661/importing-food-damages-domestic-environment-evidence-from-global-soybean-trade
#6
Jing Sun, Harold Mooney, Wenbin Wu, Huajun Tang, Yuxin Tong, Zhenci Xu, Baorong Huang, Yeqing Cheng, Xinjun Yang, Dan Wei, Fusuo Zhang, Jianguo Liu
Protecting the environment and enhancing food security are among the world's Sustainable Development Goals and greatest challenges. International food trade is an important mechanism to enhance food security worldwide. Nonetheless, it is widely concluded that in international food trade importing countries gain environmental benefits, while exporting countries suffer environmental problems by using land and other resources to produce food for exports. Our study shows that international food trade can also lead to environmental pollution in importing countries...
May 7, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29732392/bladder-cancer-genetic-susceptibility-a-systematic-review
#7
Evangelina López de Maturana, Marta Rava, Chiaka Anumudu, Olga Sáez, Dolores Alonso, Núria Malats
Background: The variant/gene candidate approach to explore bladder cancer (BC) genetic susceptibility has been applied in many studies with significant findings reported. However, results are not always conclusive due to the lack of replication by subsequent studies. Objectives: To identify all epidemiological investigations on the genetic associations with BC risk, to quantify the likely magnitude of the associations by applying metaanalysis methodology and to assess whether there is a potential for publication/reporting bias...
April 26, 2018: Bladder Cancer
https://www.readbyqxmd.com/read/29727605/the-burden-of-invasive-aspergillosis-in-patients-with-haematological-malignancy-a-meta-analysis-and-systematic-review
#8
R J van de Peppel, L G Visser, O M Dekkers, M G J de Boer
INTRODUCTION: Successful treatment of haematological malignancies is frequently complicated by invasive aspergillosis (IA), a life-threatening fungal infection that occurs in at least 10% of haematooncological patients. Case fatality rates (CFR) may fluctuate over time, depending on host pathogen interactions as well as on treatment and quality of patient care. We conducted a systematic review and metaanalysis of current - i.e. 2008-revised EORTC-MSG criteria era - incidence and case fatality rates (CFR) of IA in patients with haematological malignancy...
May 1, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29689002/response-letter-intraoperative-neurophysiological-monitoring-in-spine-surgery-a-systematic-review-and-metaanalysis
#9
Jefferson W Daniel, Ricardo Vieira Botelho, Jerônimo Milano Buzetti, Fernando Rolemberg Dantas, Franz Onishi, Eloy Russafa Neto, Eduardo de Freitas Bertolini, Marcelo Duva Borgheresi, Andrei Fernandes Joaquim
No abstract text is available yet for this article.
April 23, 2018: Spine
https://www.readbyqxmd.com/read/29605348/systematic-review-meta-analysis-comparing-successful-outcomes-after-single-vs-double-stage-laryngotracheal-reconstruction
#10
REVIEW
Reema Padia, Phayvanh Sjogren, Marshall Smith, Harlan Muntz, Gregory Stoddard, Jeremy Meier
OBJECTIVE: To compare operation-specific decannulation rates between single-stage (SSLTR) and double-stage laryngotracheal reconstruction (DSLTR) when controlling for grade of airway stenosis. METHODS: A systematic review and meta-analysis were performed using PubMed, EMBASE and Cochrane databases from 1970 to 2015 to examine primary SSLTR and DSLTR for subglottic stenosis in patients 18 years or younger. Primary outcome was decannulation or extubation after LTR...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29567836/histone-deacetylase-mediated-regulation-of-endolysosomal-ph
#11
Hari Prasad, Rajini Rao
The pH of the endolysosomal system is tightly regulated by a balance of proton pump and leak mechanisms that are critical for storage, recycling, turnover, and signaling functions in the cell. Dysregulation of endolysosomal pH has been linked to aging, amyloidogenesis, synaptic dysfunction, and various neurodegenerative disorders, including Alzheimer's disease. Therefore, understanding the mechanisms that regulate luminal pH may be key to identifying new targets for managing these disorders. Meta-analysis of yeast microarray databases revealed that nutrient-limiting conditions inhibited the histone deacetylase (HDAC) Rpd3 and thereby up-regulated transcription of the endosomal Na+ /H+ exchanger Nhx1, resulting in vacuolar alkalinization...
May 4, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29555766/the-role-of-consolidation-in-learning-context-dependent-phonotactic-patterns-in-speech-and-digital-sequence-production
#12
Nathaniel D Anderson, Gary S Dell
Speakers implicitly learn novel phonotactic patterns by producing strings of syllables. The learning is revealed in their speech errors. First-order patterns, such as "/f/ must be a syllable onset," can be distinguished from contingent, or second-order, patterns, such as "/f/ must be an onset if the vowel is /a/, but a coda if the vowel is /o/." A metaanalysis of 19 experiments clearly demonstrated that first-order patterns affect speech errors to a very great extent in a single experimental session, but second-order vowel-contingent patterns only affect errors on the second day of testing, suggesting the need for a consolidation period...
April 3, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29551054/ezetimibe-decreased-nonalcoholic-fatty-liver-disease-activity-score-but-not-hepatic-steatosis
#13
Hyo Young Lee, Dae Won Jun, Hyun Jung Kim, Hyunwoo Oh, Waqar Khalid Saeed, Hyeongsik Ahn, Ramsey C Cheung, Mindie H Nguyen
Background/Aims: A number of clinical trials reported varying effects of cholesterol lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We, therefore, assessed the changes in hepatic steatosis and NAFLD activity score (NAS) after treatment with cholesterol lowering agents in NAFLD patients by metaanalysis. Methods: The Cochrane Library, the MEDLINE, and the Embase databases were searched until May 2015, without any language restrictions, for randomized controlled trials (RCTs) and nonrandomized studies (NRSs)...
March 20, 2018: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29545454/a-systematic-review-and-metaanalysis-of-antirheumatic-drugs-and-vaccine-immunogenicity-in-rheumatoid-arthritis
#14
Sujith Subesinghe, Katie Bechman, Andrew I Rutherford, David Goldblatt, James B Galloway
OBJECTIVE: Vaccination is a key strategy to reduce infection risk in patients with rheumatoid arthritis (RA) and is advocated in internationally recognized rheumatology society guidelines. The aim was to evaluate to the effect of antirheumatic drugs on influenza and pneumococcal vaccine immunogenicity. METHODS: We conducted a systematic literature review and metaanalysis comparing the humoral response to influenza (pandemic and seasonal trivalent subunit vaccines) and pneumococcal (23-valent pneumococcal polysaccharide vaccine, 7- and 13-valent pneumococcal conjugated vaccines) vaccination in adult patients with RA treated with antirheumatic drugs...
June 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29534265/-retinal-astrocytic-hamartoma-in-neurofibromatosis-type-2-metaanalysis-and-a-case-report
#15
Daniela Aneta Starosta, Birgit Lorenz
BACKGROUND: Neurofibromatosis type 2 (NF2) is a genetic condition with an autosomal dominant pattern of inheritance and incomplete penetrance. It is characterized by multiple benign tumors of the central and peripheral nervous system including astrocytomas, ependymomas, meningeomas, and schwannomas, among which bilateral vestibular schwannomas are the most frequent. Among ocular manifestations of NF2, juvenile subcapsular cataract is the most common followed by epiretinal membranes and combined hamartomas of the retina and retinal pigment epithelium...
March 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29521265/-efficacy-of-lycopene-intake-in-primary-prevention-of-prostate-cancer-a-systematic-review-of-the-literature-and-meta-analysis
#16
Juan Guillermo Cataño, Carlos Gustavo Trujillo, Juan Ignacio Caicedo, Alejandra Bravo-Balado, Daniela Robledo, Angela Marcela Mariño-Alvarez, Adriana Pedraza, María Juliana Arcila, Mauricio Plata
OBJECTIVE: To evaluate the efficacy of lycopene intake in primary prevention of prostate cancer (PCa). METHODS: A systematic search of the literature was conducted in March 2015 and the articles published between the years 1990-2015 were reviewed. The following search terms were used: prostate cancer, prostatic neoplasm, lycopene, prevention, effectiveness and efficacy (MeSH). Publications including research in humans, written in English and whose texts were accessible were reviewed...
March 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29439921/impact-of-organizational-interventions-on-reducing-inappropriate-intravenous-immunoglobulin-ivig-usage-a-systematic-review-and-meta-analysis
#17
Calvin Diep, Andrew W Shih, Erin Jamula, Nancy M Heddle, Michael Parvizian, Christopher M Hillis
BACKGROUND: With increasing global use of intravenous immunoglobulin (IVIG), there is interest in its appropriate usage. Efforts to regulate IVIG usage have primarily taken the form of organizational interventions implemented in hospitals to monitor and improve physician prescribing. Similar interventions have proven effective in reducing the inappropriate and total hospital usage of other blood products, but their efficacy on IVIG use is less understood. Thus, we performed a systematic review of studies reporting the change in inappropriate IVIG use following such interventions in hospitals or regions...
January 31, 2018: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29401273/low-risk-of-primary-clostridium-difficile-infection-with-tetracyclines-a-systematic-review-and-metaanalysis
#18
Raseen Tariq, Janice Cho, Saloni Kapoor, Robert Orenstein, Siddharth Singh, Darrell S Pardi, Sahil Khanna
Background: The choice of antibiotics for systemic infections in patients with a high risk of Clostridium difficile infection (CDI) remains a clinical practice dilemma. Although some studies suggest that tetracyclines may be associated with a lower risk of CDI than other antibiotics, other results are conflicting. We conducted a systematic review and metaanalysis of studies that assessed the risk of CDI with tetracyclines compared to other antibiotics. Methods: We conducted a systematic search of Medline, Embase, and Web of Science from January 1978 through December 2016 to include studies that assessed the association between tetracycline use and risk of CDI...
February 1, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29397134/systematic-review-of-the-qor-15-score-a-patient-reported-outcome-measure-measuring-quality-of-recovery-after-surgery-and-anaesthesia
#19
REVIEW
J Kleif, J Waage, K B Christensen, I Gögenur
BACKGROUND: The QoR-15 is a patient-reported outcome questionnaire that measures the quality of recovery after surgery and anaesthesia. We aimed to perform a systematic review and meta-analysis of the measurement properties of the QoR-15. METHODS: Studies reporting measurement properties or interpretability of the QoR-15 after surgery were eligible for inclusion. All languages were included in the PubMed and Embase search. The COSMIN guidelines for systematic reviews of patient-reported outcome measurements were followed...
January 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/29394213/eosinophil-counts-in-the-small-intestine-and-colon-of-children-without-apparent-gastrointestinal-disease-a-meta-analysis
#20
Zoltán Kiss, Bálint Tél, Nelli Farkas, András Garami, Áron Vincze, Judit Bajor, Patrícia Sarlós, Katalin Márta, Adrienn Erős, Alexandra Mikó, Zsolt Szakács, Dániel Pécsi, Péter Mátrai, Péter Hegyi, Gábor Veres
The aim of the current study was to review the available data regarding eosinophil density in healthy tissue specimen originating from lower gastrointestinal segments to support suggested diagnostic cutoffs widely used in clinical practice. A systematic search was performed in 3 different databases. Calculations were made with Comprehensive MetaAnalysis software using random-effects model. Cell number measurements were pooled using the random-effects model and displayed on forest plots. Summary point estimations, 95% confidence intervals (CIs), and 95% prediction intervals (PIs) were calculated...
April 30, 2018: Journal of Pediatric Gastroenterology and Nutrition
keyword
keyword
40920
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"