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https://www.readbyqxmd.com/read/28429913/effect-of-glucomannan-on-functional-constipation-in-children-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#1
Yong Han, Lei Zhang, Xiang-Qun Liu, Zhi-Jun Zhao, Lu-Xian Lv
BACKGROUND AND OBJECTIVES: Constipation, a common complaint in children, considerably affects the quality of life. This systematic review assessed the treatment effects of glucomannan on children with constipation by summarising evidence from previous randomised controlled trials (RCTs). METHODS AND STUDY DESIGN: A comprehensive electronic literature search was conducted for identifying eligible RCTs that evaluated the effectiveness of glucomannan. The results were reported as mean differences (MDs), standardised mean differences (SMDs), and risk ratios (RRs) with 95% confidence intervals (CIs)...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28426628/ocular-hypertension-and-glaucoma-following-vitrectomy-a-systematic-review
#2
Alba Miele, Andrea Govetto, Carlo Fumagalli, Simone Donati, Ilaria Biagini, Claudio Azzolini, Stanislao Rizzo, Gianni Virgili
PURPOSE: Pars plana vitrectomy has been reported to increase the risk of ocular hypertension and open-angle glaucoma. The authors conducted a systematic review of randomized and nonrandomized studies to compare the incidence of open-angle glaucoma and ocular hypertension in vitrectomized versus nonvitrectomized eyes. METHODS: A literature search was performed using MEDLINE and EMBASE until August 2016. Data on ocular hypertension and open-angle glaucoma incidence and mean intraocular pressure after at least 1 year were pooled using random-effects metaanalysis models...
April 19, 2017: Retina
https://www.readbyqxmd.com/read/28421599/surgery-versus-conservative-management-of-endometriomas-in-subfertile-women-a-systematic-review
#3
Jacob Brink Laursen, Jeppe Bennekou Schroll, Kirsten T Macklon, Martin Rudnicki
INTRODUCTION: Endometriomas are present in up to 44% of all women with endometriosis and have a detrimental effect on fertility. However, it is controversial whether endometriomas should be surgically removed before assisted reproduction technology (ART). Our purpose was to evaluate whether surgical stripping of endometriomas in subfertile women improves the chance of a live birth. Secondary outcomes were impact on ovarian reserve and pain. Material and methods We conducted a systematic review and metaanalysis with results reported in accordance to the PRISMA guidelines...
April 19, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28407199/comprehensive-geriatric-assessment-for-prevention-of-delirium-after-hip-fracture-a-systematic-review-of-randomized-controlled-trials
#4
Lynn Shields, Victoria Henderson, Robert Caslake
OBJECTIVES: To assess the efficacy of comprehensive geriatric assessment (CGA) in prevention of delirium after hip fracture. DESIGN: Systematic review and metaanalysis. SETTING: Ward based models on geriatrics wards and visiting team based models on orthopaedics wards were included. PARTICIPANTS: Four trials (three European, one U.S.; 973 participants) were identified. Two assessed ward-based, and two assessed team-based interventions...
April 13, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28397459/assessment-of-the-link-between-xrcc1-arg399gln-polymorphism-and-breast-cancer-a-meta-analysis-in-a-single-ethnic-group
#5
Xin-Ping Chen, Hai-Feng Wen, Fan Zhang, Wei-Hua Xu, Zhi-Chao Ma, Sheng-Miao Fu
BACKGROUND: Although various individual studies have been conducted to determine the association between X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism and breast cancer, the results remain inconclusive. To assess the influence of XRCC1 Arg399Gln polymorphism on the risk of breast cancer, a metaanalysis was performed in a single ethnic group. METHODS: Eligible studies were identified via databases such as PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure, and Chinese Biology Medicine, throughout February 2016...
April 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28369687/caregiver-integration-during-discharge-planning-for-older-adults-to-reduce-resource-use-a-metaanalysis
#6
Juleen Rodakowski, Philip B Rocco, Maqui Ortiz, Barbara Folb, Richard Schulz, Sally C Morton, Sally Caine Leathers, Lu Hu, A Everette James
OBJECTIVES: To determine the effect of integrating informal caregivers into discharge planning on postdischarge cost and resource use in older adults. DESIGN: A systematic review and metaanalysis of randomized controlled trials that examine the effect of discharge planning with caregiver integration begun before discharge on healthcare cost and resource use outcomes. MEDLINE, EMBASE, and the Cochrane Library databases were searched for all English-language articles published between 1990 and April 2016...
April 3, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28317680/risk-for-microbial-keratitis-comparative-metaanalysis-of-contact-lens-wearers-and-post-laser-in-situ-keratomileusis-patients
#7
Jordan Masters, Mehmet Kocak, Aaron Waite
PURPOSE: To compare the risk for microbial keratitis in contact lens wearers stratified by wear schedule with the risk after laser in situ keratomileusis (LASIK). SETTING: Hamilton Eye Institute and Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA. DESIGN: Comparative metaanalysis and literature review. METHODS: An extensive literature search was performed in the PubMed database between December 2014 and July 2015...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28289821/single-dose-local-anesthetics-exhibit-a-type-dose-and-time-dependent-chondrotoxic-effect-on-chondrocytes-and-cartilage-a-systematic-review-of-the-current-literature
#8
REVIEW
Peter Cornelius Kreuz, Matthias Steinwachs, Peter Angele
PURPOSE: Many studies have shown that local anesthetics may impede chondrocyte metabolism. However, the influence of a single-dose local anesthetics is controversial. The aim of this metaanalysis was to review the literature for studies investigating the cytotoxic effects of single-dose local anesthetics on chondrocytes and cartilage. METHODS: A comprehensive literature search was performed using established search engines (Medline, Embase) to identify studies, investigating the influence of single-dose local anesthetics on cartilage...
March 13, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28288547/neuropsychological-correlates-of-schizotypy-a-systematic-review-and-meta-analysis-of-cross-sectional-studies
#9
Sara Siddi, Donatella Rita Petretto, Antonio Preti
INTRODUCTION: Cognitive deficits can precede the onset of psychotic episodes and predict the onset of the illness in individuals with schizotypy traits. In some studies, high levels of schizotypy were associated with impairments in memory, attention, executive functions, and verbal fluency. This review provides a more comprehensive understanding of cognitive impairments related to schizoytpy. METHODS:  A systematic review of "schizotypy and neuropsychological measures" was conducted, and it retrieved 67 studies...
March 13, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28273828/association%C3%A2-of%C3%A2-serum%C3%A2-manganese%C3%A2-levels%C3%A2-with%C3%A2-alzheimer-s%C3%A2-disease%C3%A2-and%C3%A2-mild%C3%A2-cognitive%C3%A2-impairment-%C3%A2-a%C3%A2-systematic%C3%A2-review%C3%A2-and%C3%A2-meta-analysis
#10
Ke Du, Mingyan Liu, Yanzhu Pan, Xin Zhong, Minjie Wei
Manganese (Mn) is one of the most studied environmental heavy metals linked to Alzheimer's disease (AD). However, it remains unclear whether serum Mn levels are associated with AD and mild cognition impairment (MCI, a prodromal stage of AD). We conducted a metaanalysis to analyze the serum Mn levels in patients with AD and MCI. A systematic database search of PubMed, Web of Science, and the China National Knowledge Infrastructure (CNKI) identified 17 studies, including 836 cases and 1254 health controls (HC)...
March 3, 2017: Nutrients
https://www.readbyqxmd.com/read/28266901/collaborative-approach-of-individual-participant-data-of-prospective-studies-of-de-escalation-in-non-immunosuppressed-critically-ill-patients-with-sepsis
#11
Antonio Gutiérrez-Pizarraya, Marc Leone, Jose Garnacho-Montero, Claude Martin, Ignacio Martin-Loeches
BACKGROUND: There is a concern to conduct de-escalation in very sick patients. AIMS: To determine if de-escalation is feasible in ICU settings. METHODS: We performed a metaanalysis of published studies conducted comparing de-escalation (defined by withdrawal of at least one antimicrobial empirically prescribed, switch to a new antimicrobial with narrower spectrum and withdrawal of at least one antimicrobial plus change of another drug to a new one with narrower spectrum) in non-immunocompromised patients with sepsis admitted to ICU...
April 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28245681/-does-the-sidedness-determine-the-first-line-treatment-of-irresectable-metastatic-colorectal-cancer
#12
Tamás Kullmann, István Sipőcz, Tamás Pintér
INTRODUCTION AND AIM: Median life expectancy of non-resectable metastatic colorectal cancer may surpass three years. However, several points of the treatment strategy are subject of ongoing debate. Optimal sequence of targeted agents is not elucidated either. Based on retrospective analyses of six clinical studies and a metaanalysis, the superiority of anti-EGFR agents such as cetuximab and panitumumab over anti-VEGF bevacizumab has been proposed in the treatment of left sided tumours...
March 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28236811/neuropsychological-performance-changes-following-subthalamic-versus-pallidal-deep-brain-stimulation-in-parkinson-s-disease-a-systematic-review-and-metaanalysis
#13
Ahmed Elgebaly, Mohamed Elfil, Attia Attia, Mayar Magdy, Ahmed Negida
BACKGROUND: Studies comparing subthalamus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) for the management of Parkinson's disease in terms of neuropsychological performance are scarce and heterogeneous. Therefore, we performed a systematic review and metaanalysis to compare neuropsychological outcomes following STN DBS versus GPi DBS. METHODS: A computer literature search of PubMed, the Web of Science, and Cochrane Central was conducted. Records were screened for eligible studies, and data were extracted and synthesized using Review Manager (v...
February 27, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28206891/survival-of-adhesive-restorations-for-primary-molars-a-systematic-review-and-metaanalysis-of-clinical-trials
#14
Ana Paula Santos, Ianny K D Moreira, Ana Carolina Scarpelli, Isabela A Pordeus, Saul M Paiva, Carolina C Martins
PURPOSE: The purpose of this study was to assess the scientific evidence regarding the survival and clinical performance of adhesive materials for primary molars, comparing composite resin (CR), conventional glass ionomer cement (GIC), resin-modified glass ionomer (RMGIC), silver-reinforced glass ionomer cement, and compomer. METHODS: Six databases were searched without restrictions regarding language or year of publication. Meta-analysis was conducted; risk ratios (RRs) and 95 percent confidence intervals (95% CI) were calculated...
October 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28202743/the-cost-effectiveness-of-sequences-of-biological-disease-modifying-antirheumatic-drug-treatment-in-england-for-patients-with-rheumatoid-arthritis-who-can-tolerate-methotrexate
#15
Matt D Stevenson, Allan J Wailoo, Jonathan C Tosh, Monica Hernandez-Alava, Laura A Gibson, John W Stevens, Rachel J Archer, Emma L Simpson, Emma S Hock, Adam Young, David L Scott
OBJECTIVE: To ascertain whether strategies of treatment with a biological disease-modifying antirheumatic drug (bDMARD) are cost-effective in an English setting. Results are presented for those patients with moderate to severe rheumatoid arthritis (RA) and those with severe RA. METHODS: An economic model to assess the cost-effectiveness of 7 bDMARD was developed. A systematic literature review and network metaanalysis was undertaken to establish relative clinical effectiveness...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28196551/effects-of-hospital-palliative-care-on-health-length-of-stay-and-in-hospital-mortality-across-intensive-and-non-intensive-care-units-a-systematic-review-and-metaanalysis
#16
Xibei Liu, Yaser Dawod, Alex Wonnaparhown, Amaan Shafi, Loomee Doo, Ji Won Yoo, Eunjeong Ko, Youn Seon Choi
OBJECTIVE: Hospital palliative care has been shown to improve quality of life and optimize hospital utilization for seriously ill patients who need intensive care. The present review examined whether hospital palliative care in intensive care (ICU) and non-ICU settings will influence hospital length of stay and in-hospital mortality. METHOD: A systematic search of CINAHL/EBSCO, the Cochrane Library, Google Scholar, MEDLINE/Ovid, PubMed, and the Web of Science through 12 October 2016 identified 16 studies that examined the effects of hospital palliative care and reported on hospital length of stay and in-hospital death...
February 15, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28184421/risk-of-active-tuberculosis-in-patients-with-cancer-a-systematic-review-and-metaanalysis
#17
Matthew P Cheng, Claire Nour Abou Chakra, Cedric P Yansouni, Sonya Cnossen, Ian Shrier, Dick Menzies, Christina Greenaway
No abstract text is available yet for this article.
December 13, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28182208/systematic-review-and-metaanalysis-of-acute-kidney-injury-associated-with-concomitant-vancomycin-and-piperacillin-tazobactam
#18
Drayton A Hammond, Melanie N Smith, Chenghui Li, Sarah M Hayes, Katherine Lusardi, P Brandon Bookstaver
No abstract text is available yet for this article.
February 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28164670/prognostic-value-of-expression-of-micrornas-in-non-small-cell-lung-cancer-a-systematic-review-and-meta-analysis
#19
Bingxiang Zhan, Dapeng Lu, Peng Luo, Baolong Wang
BACKGROUND: microRNAs are widely involved in a variety of life processes and considered as potential biomarkers of tumor prognosis. A growing number of studies have documented that miRNAs were associated with outcome in NSCLC patients and can act as a prognostic marker. However, existing studies concerning the relationship between miRNAs and outcome in NSCLC patients were contentious and dispersive. Therefore, a systematic metaanalysis to explore the prognostic value of miRNAs on NSCLC patients is urgently needed...
November 1, 2016: Clinical Laboratory
https://www.readbyqxmd.com/read/28164573/association-studies-of-cyp1a1-exon7-polymorphism-and-gstm1-interaction-with-esophageal-cancer-risk-a-meta-analysis-in-the-chinese-population
#20
Xin-Ping Chen, Da-Feng Xu, Wei-Hua Xu, Zhi-Chao Ma, Jia Yao, Sheng-Miao Fu
BACKGROUND: Although many epidemiological studies have investigated the CYP1A1 exon7 polymorphism and -GSTM1 interaction with esophageal cancer (EC), definite conclusions cannot be drawn. This study was conducted to explore this association in the Chinese population using meta-analysis. METHODS: Relevant studies were identified from PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure, and Chinese Biology Medicine databases published through August 2015...
September 1, 2016: Clinical Laboratory
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