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Paul K R Dasari, Judson P Jones, Michael E Casey, Yuanyuan Liang, Vasken Dilsizian, Mark F Smith
BACKGROUND: The effect of time-of-flight (TOF) and point spread function (PSF) modeling in image reconstruction has not been well studied for cardiac PET. This study assesses their separate and combined influence on 82 Rb myocardial perfusion imaging in obese patients. METHODS: Thirty-six obese patients underwent rest-stress 82 Rb cardiac PET. Images were reconstructed with and without TOF and PSF modeling. Perfusion was quantitatively compared using the AHA 17-segment model for patients grouped by BMI, cross-sectional body area in the scanner field of view, gender, and left ventricular myocardial volume...
June 15, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
John S Garrett, Steven Sonnamaker, Yahya Daoud, Hao Wang, Dion Graybeal
Background: The aim of the study was to determine the optimal set point for the critical event benchmarks described in stroke guidelines and validate the ability of these goals to predict successful administration of intravenous thrombolysis within 60 min of hospital arrival. Methods: This was a retrospective cohort analysis of patients with acute ischemic stroke who received intravenous thrombolysis following presentation to the emergency department. The national benchmarks for time intervals associated with the completion of critical events required to determine candidacy for thrombolysis were evaluated for the ability to predict successful administration of thrombolysis within 60 min of hospital arrival...
July 2018: Journal of Clinical Medicine Research
David Andreu, Juan Fernández-Armenta, Juan Acosta, Diego Penela, Beatriz Jáuregui, David Soto-Iglesias, Vladimir Syrovnev, Elena Arbelo, José María Tolosana, Antonio Berruezo
BACKGROUND: Previously proposed algorithms to predict the ventricular tachycardia (VT) exit site have been based on diverse left ventricle (LV) models, but none of them identify the precise region of origin on electroanatomical mapping (EAM). Moreover, no ECG algorithm has been tested to predict the region of origin of scar-related VTs in non-ischemic patients. OBJECTIVE: To validate a simple electrocardiographic algorithm to identify the segment of origin (SgO) VT relative to the 17-segment American Heart Association (AHA) model in patients with structural heart disease (SHD)...
June 11, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Gulam Muhammed Al Kibria, Krystal Swasey, Allysha Choudhury, Vanessa Burrowes, Kristen A Stafford, S M Iftekhar Uddin, Mohammadhassan Mirbolouk, Atia Sharmeen, Angela Kc, Dipak K Mitra
We analyzed the Bangladesh Demographic and Health Survey 2011 data to examine absolute differences in hypertension prevalence according to the hypertension definition of the "2017 American College of Cardiology/American Heart Association (2017 ACC/AHA) Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults" and "Seventh Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7)" 2003 guidelines. Among 7839 participants ≥35 years, the JNC7 and 2017 ACC/AHA classified 25...
June 13, 2018: Journal of Human Hypertension
Michael D Miedema, Zeina A Dardari, Sina Kianoush, Salim S Virani, Joseph Yeboah, Thomas Knickelbine, Veit Sandfort, Carlos J Rodriguez, Khurram Nasir, Michael J Blaha
BACKGROUND: The potential impact of the 2016 United States Preventive Services Task Force (USPSTF) guidelines on statins for primary prevention of atherosclerotic cardiovascular disease (ASCVD) warrants further analysis. METHODS AND RESULTS: We studied participants from MESA (Multi-Ethnic Study of Atherosclerosis) aged 40 to 75 years and not on statins. We compared statin eligibility at baseline (2000-2002) and over follow-up between USPSTF and the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines...
June 13, 2018: Journal of the American Heart Association
Angela Lowenstern, Shuang Li, Ann Marie Navar, Salim Virani, L Veronica Lee, Michael J Louie, Eric D Peterson, Tracy Y Wang
BACKGROUND: The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) cholesterol guideline recommends statin treatment based on patients' predicted atherosclerotic cardiovascular disease (ASCVD) risk. Whether clinician-reported guideline adoption translates to implementation into practice is unknown. OBJECTIVES: We aimed to compare clinician lipid management in hypothetical scenarios versus observed practice. METHODS: The PALM Registry asked 774 clinicians how they would treat 4 hypothetical scenarios of primary prevention patients with: (1) diabetes; (2) high 10-year ASCVD risk (≥7...
June 2018: American Heart Journal
Jinwei Gao, Bingwen Xi, Kai Chen, Rui Song, Ting Qin, Jun Xie, Liangkun Pan
Stress is an important contributing factor in the outbreak of infectious fish diseases. To comprehensively understand the impact of catecholamine stress hormone norepinephrine (NE) on the pathogenicity of Aeromonas hydrophila, we assessed variations in bacterial growth, virulence-related genes expression and virulence factors activity after NE addition in serum-SAPI medium. Further, we assessed the effects of NE on A. hydrophila virulence in vivo by challenging fish with pathogenic strain AH196 and following with or without NE injection...
June 13, 2018: MicrobiologyOpen
Anne Boucher, Agnes Meybeck, Kazali Alidjinou, Thomas Huleux, Nathalie Viget, Veronique Baclet, Michel Valette, Isabelle Alcaraz, Eveline Sauser, Laurence Bocket, Ajana Faiza
OBJECTIVES: Since February 2017, an increase of acute hepatitis A (AHA) cases has been notified in North of France. We aimed to report clinical and virological features of 49 cases treated in three hospitals in Lille European Metropolis (LEM). METHODS: All adult patients treated for AHA in 3 LEM hospitals between 20 February and 5 July 2017 were included. Demographic characteristics, exposure risk factors to hepatitis A virus (HAV), AHA manifestations and concomitant sexually transmitted infections (STI) were retrospectively recorded...
June 9, 2018: Sexually Transmitted Infections
Isabelle Koné-Paut, Rolando Cimaz, Jethro Herberg, Oliver Bates, Aurelia Carbasse, Jean Pierre Saulnier, Maria Cristina Maggio, Jordi Anton, Maryam Piram
OBJECTIVES: To identify the clinical characteristics, reasons for use and response to treatment with anakinra in a series of patients with Kawasaki Disease (KD). STUDY DESIGN: A retrospective chart review of patients treated with anakinra for KD diagnosed according to the AHA criteria. We compared clinical, biological and echocardiographic characteristics of KD before and after anakinra use. We analysed reasons for use of anakinra, and compared treatment regimens used in 7 European KD referral centres...
June 6, 2018: Autoimmunity Reviews
Kimia Honarmand, Chantal Mepham, Craig Ainsworth, Zahira Khalid
AIM OF THE STUDY: Identifying modifiable factors associated with survival following in-hospital cardiac arrest is crucial. The purpose of this study was to determine the extent to which adherence to the 2010 American Heart Association (AHA) Advanced Cardiac Life Support (ACLS) guidelines in their entirety affects patient outcomes. In addition, we explored the role of code leader training level on patient outcomes. METHODS: We conducted a retrospective review of records for cardiac arrests that occurred on hospital wards and were run by the hospital code team, at three tertiary care centres over 2 to 4 years...
June 6, 2018: Resuscitation
Raymond Y Yeow, Garth W Strohbehn, Calvin M Kagan, Christopher M Petrilli, Jamuna K Krishnan, Karli Edholm, L Scott Sussman, Jaime F Blanck, Remus I Popa, Amit K Pahwa
In-hospital continuous electrocardiographic monitoring, commonly referred to as telemetry, has allowed for rapid recognition of life-threatening conditions, including complex arrhythmias and myocardial ischemia. However, inappropriate use can lead to unnecessary downstream testing from "false alarms," which in turn affects clinician efficiency and increases health care costs without benefiting patients. For these reasons, the Society of Hospital Medicine's Choosing Wisely campaign recommended use of a protocol-driven discontinuation of telemetry...
June 4, 2018: JAMA Internal Medicine
João O Malva, Alda Amado, Alexandra Rodrigues, Anabela Mota-Pinto, Ana F Cardoso, Ana M Teixeira, Ana Todo-Bom, António Devesa, António F Ambrósio, António L Cunha, Bárbara Gomes, Carina Dantas, Cidalina Abreu, Isabel Santana, Jean Bousquet, João Apóstolo, Lúcia Santos, Lúcio Meneses de Almeida, Maddalena Illario, Rafaela Veríssimo, Vitor Rodrigues, Manuel T Veríssimo
Challenges posed by demographic changes and population aging are key priorities for the Horizon 2020 Program of the European Commission. Aligned with the vision of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), the development, exchange, and large-scale adoption of innovative good practices is a key element of the responses required to ensure all European citizens remain as active and healthy as possible as they age. Urged by the need of developing scalable disruptive innovation across Europe, the European Commission and the EIP on AHA created the Reference Sites; local coalition of partners that develop good practices to support AHA...
2018: Frontiers in Medicine
Kate H Magid, Debra Heard, Comilla Sasson
BACKGROUND: Training middle school students to perform hands-only cardiopulmonary resuscitation (HOCPR) is a potential method to increase overall rates of bystander cardiopulmonary resuscitation (CPR). We aimed to examine the feasibility of teaching this population CPR using teacher-implemented education sessions guided by American Heart Association (AHA) training kits and resources. METHODS: We conducted a national HOCPR training campaign in middle schools during the 2014-2015 school year...
July 2018: Journal of School Health
Qurat-Ul-Ain Jelani, Mikhail Petrov, Sara C Martinez, Lene Holmvang, Khaled Al-Shaibi, Mirvat Alasnag
PURPOSE OF REVIEW: Peripheral arterial disease (PAD) is the third most common manifestation of cardiovascular disease (CVD), following coronary artery disease (CAD) and stroke. PAD remains underdiagnosed and under-treated in women. RECENT FINDINGS: Women with PAD experience more atypical symptoms and poorer overall health status. The prevalence of PAD in women increases with age, such that more women than men have PAD after the age of 40 years. There is under-representation of PAD patients in clinical trials in general and women in particular...
June 2, 2018: Current Atherosclerosis Reports
R Godet, A Bruneau, B Vielle, F Vincent, T Le Tourneau, F Carre, D Hupin, J F Hamel, P Abraham, S Henni
INTRODUCTION: The American Heart Association (AHA) recommendations for diagnosing peripheral artery disease (PAD) after exercise are a decrease > 20% of ankle brachial index (ABI) or > 30 mmHg of ankle systolic blood pressure (ASBP) from resting values. We evaluated ABI and ASBP values during incremental maximal exercise in physically active and asymptomatic patients. METHODS: Patients (n=726) underwent incremental bicycle tests with pre and post-exercise recording of all four limbs arterial pressures simultaneously...
June 1, 2018: Scandinavian Journal of Medicine & Science in Sports
Kirsten S Dorans, Katherine T Mills, Yang Liu, Jiang He
BACKGROUND: Hypertension is a major risk factor for cardiovascular disease and all-cause mortality. Compared with prior guidelines, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guideline recommends lower blood pressure thresholds for defining hypertension, for initiating antihypertensive medication, and for antihypertensive medication treatment goals. METHODS AND RESULTS: To better understand potential impacts of the 2017 guideline, we studied trends in mean systolic blood pressure and diastolic blood pressure, prevalence and burden of hypertension, and proportion of controlled hypertension in the US adult population aged ≥20 from 1999 through 2016...
June 1, 2018: Journal of the American Heart Association
Nassir F Marrouche, Mobin Kheirkhahan, Johannes Brachmann
In the last two decades, catheter ablation of atrial fibrillation (AF) has evolved into a procedure with both efficacy in reduction of AF burden and safety. This has led to changes in guidelines from ESC, AHA/ACC and HRS1, 2 now recommending a catheter ablation procedure as a viable first line treatment option for patients suffering from AF with and without heart failure (HF). Current recommendations are based on relief of symptoms and not prevention of mortality and morbidity.
May 30, 2018: Circulation
Kristen M Garcia, Emily Martin, Whitney R Garney, Kristin M Primm
INTRODUCTION: The American Heart Association (AHA) was funded to implement a nationally led initiative to implement policy, systems, and environment (PSE) interventions in communities across the United States. In Cohort 1, 15 communities were tasked with working with local community partners to plan and implement initiatives. METHOD: Engaged as the evaluators, Texas A&M researchers conducted telephone interviews with project managers (employed by AHA) and community partners representing the 15 communities...
May 1, 2018: Health Promotion Practice
Rob Sips
No abstract text is available yet for this article.
May 29, 2018: Schizophrenia Bulletin
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