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https://www.readbyqxmd.com/read/28318771/cross-protection-to-new-drifted-influenza-a-h3-viruses-and-prevalence-of-protective-antibodies-to-seasonal-influenza-during-2014-in-portugal
#1
Raquel Guiomar, Susana Pereira da Silva, Patrícia Conde, Paula Cristóvão, Ana Carina Maia, Pedro Pechirra, Ana Paula Rodrigues, Baltazar Nunes, Luís Milho, Ana Paula Coelho, Aida Fernandes, Paula Caseiro, Fernando Rodrigues, Lurdes Correia, João Pereira-Vaz, Sofia Almeida, Paula Branquinho, Rita Côrte-Real, Regina Viseu, Maria João Peres, Raquel Sanches, Filipa Dantas, Ludovina Freitas, Graça Andrade, Manuel Maurílio, Filomena Caldeira, Rita Cabral Veloso, Luisa Mota-Vieira, Marta Soares, Ana Rita Couto, Jácome Bruges-Armas, Rita Mouro Pinto, Joana Sobrinho Simões, Maria do Rosário Costa, João Tiago Guimarães, Luís Martins, Mário Cunha
INTRODUCTION: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portuguese population. MATERIALS AND METHODS: We developed a cross-sectional study based on a convenience sample of 626 sera collected during June 2014, covering all age groups, both gender and all administrative health regions of Portugal...
March 15, 2017: Vaccine
https://www.readbyqxmd.com/read/28304102/design-synthesis-and-cytotoxic-evaluation-of-certain-7-chloro-4-piperazin-1-yl-quinoline-derivatives-as-vegfr-ii-inhibitors
#2
Mohamed Nabil Aboul-Enein, Aida M Abd El-Sattar El-Azzouny, Fatma Abdel-Fattah Ragab, Mohamed Farouk Hamissa
Signaling pathway inhibition of VEGFR-II is visualized as valuable tool in cancer management. In the current study, the synthesis of novel 1-4-(7-chloroquinolin-4-yl)piperazin-1-yl)-2-(N-substituted-amino)-ethanone derivatives (4a-t) was achieved through the amination of 2-chloro-1-(4-(7-chloroquinolin-4-yl)piperazin-1-yl)ethanone (3) with different secondary amines. The structures of the target compounds were confirmed by IR, (1) H-NMR, (13) C-NMR, HRMS, and microanalysis. Compounds 4a-t were subjected to in vitro anticancer screening against human breast cancer (MCF-7) and prostate cancer (PC3) cell lines...
March 17, 2017: Archiv der Pharmazie
https://www.readbyqxmd.com/read/28302528/association-between-enteric-protozoan-parasites-and-gastrointestinal-illness-among-hiv-and-tuberculosis-infected-individuals-in-the-chowke-district-southern-mozambique
#3
María José Irisarri-Gutiérrez, Marta Hernández-de Mingo, Aida de Lucio, Horacio Gil, Lucía Morales, Raimundo Seguí, Edy Nacarapa, Carla Muñoz-Antolí, Fernando Jorge Bornay-Llinares, José Guillermo Esteban, David Carmena
Human immune deficiency virus (HIV) and tuberculosis (TB) infections remain major public health issues globally, particularly in sub-Saharan Africa. Impairment of both cell-mediated and humoral immunity by HIV and/or TB infections may limit the host's defences against other pathogens, including the diarrheagenic protozoan Cryptosporidium spp., Giardia intestinalis, and Entamoeba histolytica. During September-December 2015 a cross-sectional study was conducted to assess the prevalence and molecular diversity of these enteric parasites among HIV- and/or TB-infected patients at a medical reference centre in Chowke district, southern Mozambique...
March 14, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28298226/addressing-the-double-burden-of-diabetes-and-tuberculosis-lessons-from-kyrgyzstan
#4
Jolene Skordis-Worrall, Jeff Round, Matthias Arnold, Aida Abdraimova, Baktygul Akkazieva, David Beran
BACKGROUND: The incidence of diabetes and tuberculosis co-morbidity is rising, yet little work has been done to understand potential implications for health systems, healthcare providers and individuals. Kyrgyzstan is a priority country for tuberculosis control and has a 5% prevalence of diabetes in adults, with many health system challenges for both conditions. METHODS: Patient exit interviews collected data on demographic and socio-economic characteristics, health spending and care seeking for people with diabetes, tuberculosis and both diabetes and tuberculosis...
March 15, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28297585/electromechanical-conditioning-of-adult-progenitor-cells-improves-recovery-of-cardiac-function-after-myocardial-infarction
#5
Aida Llucià-Valldeperas, Carolina Soler-Botija, Carolina Gálvez-Montón, Santiago Roura, Cristina Prat-Vidal, Isaac Perea-Gil, Benjamin Sanchez, Ramon Bragos, Gordana Vunjak-Novakovic, Antoni Bayes-Genis
Cardiac cells are subjected to mechanical and electrical forces, which regulate gene expression and cellular function. Therefore, in vitro electromechanical stimuli could benefit further integration of therapeutic cells into the myocardium. Our goals were (a) to study the viability of a tissue-engineered construct with cardiac adipose tissue-derived progenitor cells (cardiac ATDPCs) and (b) to examine the effect of electromechanically stimulated cardiac ATDPCs within a myocardial infarction (MI) model in mice for the first time...
March 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28289054/final-touches-and-quality-control-on-the-assembly-of-the-eukaryotic-ribosome
#6
Aida Razi, Joaquin Ortega
No abstract text is available yet for this article.
March 13, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28285809/-an-unusual-glial-tumor
#7
Aida Khadhar, Alia Zehani, Ines Chelly, Imed Ben Said, Slim Haouet, Nidhameddine Kchir
No abstract text is available yet for this article.
March 9, 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/28285133/modification-of-atgrdp1-gene-expression-affects-silique-and-seed-development-in-arabidopsis-thaliana
#8
Aída Araceli Rodríguez-Hernández, Carlos Vladimir Muro-Medina, Jocelin Itzel Ramírez-Alonso, Juan Francisco Jiménez-Bremont
Glycine Rich Proteins (GRPs) are induced at different developmental stages and in specific plant tissues. Recently, we described a novel Arabidopsis gene encoding a short glycine-rich domain protein (AtGRDP1). This gene is involved in abiotic stress responsiveness; the Atgrdp1-null mutant seeds were more sensitive to stress, while the opposite phenotype was achieved by AtGRDP1 overexpression. In this study, we analyzed the phenotype of the fruits produced by Arabidopsis Atgrdp1 mutants and 35S::AtGRDP1 overexpression lines...
March 8, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28284389/biochemical-analyses-of-cerebrospinal-fluid-for-the-diagnosis-of-neurometabolic-conditions-what-can-we-expect
#9
Marta Batllori, Marta Molero-Luis, Mercedes Casado, Cristina Sierra, Rafael Artuch, Aida Ormazabal
In this article, we review the state-of-the-art analysis of different biomarkers in the cerebrospinal fluid for the diagnosis of genetically conditioned, rare, neurometabolic diseases, including glucose transport defects, neurotransmitter (dopamine, serotonin, and gamma-aminobutyric acid) and pterin deficiencies, and vitamin defects (folate, vitamin B6, and thiamine) that affect the brain. The analysis of several key metabolites are detailed, which thus highlights the preanalytical and analytical factors that should be cautiously controlled to avoid misdiagnosis; moreover, these factors may facilitate an adequate interpretation of the biochemical profiles in the context of severe neuropediatric disorders...
November 2016: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/28281153/a-unique-historical-case-to-understand-the-present-sustainable-development
#10
Astrid Barona, Begoña Etxebarria, Aida Aleksanyan, Gorka Gallastegui, Naiara Rojo, Estibaliz Diaz-Tena
Every innovation seeks to become a profitable business, with this considered to be the engine for economic prosperity. When an innovation is revolutionary, its long-term consequences can be revolutionary too. The Haber-Bosh process for ammonia synthesis is arguably the twentieth century's most significant innovation, and its importance to global food production and its impact on the environment are not expected to diminish over the coming decades. The historical case of the ammonia synthesis process invented by Fritz Haber and the ensuing innovation provides an incomparable opportunity to illustrate the interactions across contemporary needs, prominent scientists, political concerns, moral dilemmas, ethics, governance and environmental implications at a time when the concept of sustainability was still in its infancy...
March 9, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28278278/dynamic-changes-of-the-respiratory-microbiota-and-its-relationship-to-fecal-and-blood-microbiota-in-healthy-young-cats
#11
Aida I Vientós-Plotts, Aaron C Ericsson, Hansjorg Rindt, Megan E Grobman, Amber Graham, Kaitlin Bishop, Leah A Cohn, Carol R Reinero
Advances in the field of metagenomics using culture-independent methods of microbial identification have allowed characterization of rich and diverse communities of bacteria in the lungs of healthy humans, mice, dogs, sheep and pigs. These data challenge the long held belief that the lungs are sterile and microbial colonization is synonymous with pathology. Studies in humans and animals demonstrate differences in the composition of airway microbiota in health versus disease suggesting respiratory dysbiosis occurs...
2017: PloS One
https://www.readbyqxmd.com/read/28277024/structural-social-support-and-cardiovascular-disease-risk-factors-in-hispanic-latino-adults-with-diabetes-results-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#12
Rosalba Hernandez, Mercedes Carnethon, Aida L Giachello, Frank J Penedo, Donghong Wu, Orit Birnbaum-Weitzman, Rebeca Espinoza Giacinto, Linda C Gallo, Carmen R Isasi, Neil Schneiderman, Yanping Teng, Donglin Zeng, Martha L Daviglus
OBJECTIVE(S): Cross-sectional and longitudinal studies have yielded inconsistent findings on the associations of social support networks with cardiovascular health in Hispanic/Latino adults with diabetes. We examined the cross-sectional associations of structural social support and traditional cardiovascular disease (CVD) risk factors in a diverse sample of Hispanic/Latino adults with diabetes. RESEARCH DESIGN AND METHODS: This analysis included 2994 adult participants ages 18-74 with diabetes from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL - 2008-2011)...
February 23, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28270484/differences-in-incidence-of-diabetic-retinopathy-between-type-1-and-2-diabetes-mellitus-a-nine-year-follow-up-study
#13
Pedro Romero-Aroca, Raul Navarro-Gil, Aida Valls-Mateu, Ramon Sagarra-Alamo, Antonio Moreno-Ribas, Nuria Soler
BACKGROUND/AIMS: To determine the incidence of any diabetic retinopathy (any-DR), sight-threatening diabetic retinopathy (STDR) and diabetic macular oedema (DMO) and their risk factors in type 1 diabetes mellitus (T1DM) over a screening programme. METHODS: Nine-year follow-up, prospective population-based study of 366 patients with T1DM and 15 030 with T2DM. Epidemiological risk factors were as follows: current age, age at DM diagnosis, sex, type of DM, duration of DM, arterial hypertension, levels of glycosylated haemoglobin (HbA1c), triglycerides, cholesterol fractions, serum creatinine, estimated glomerular filtration rate (eGFR) and urine albumin to creatinine ratio (UACR)...
March 7, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28269376/characterizing-graphene-modified-electrodes-for-interfacing-with-arduino%C3%A2-based-devices
#14
Farrah Aida Arris, Mohamad Hafiz Ithnin, Wan Wardatul Amani Wan Salim
Portable low-cost platform and sensing systems for identification and quantitative measurement are in high demand for various environmental monitoring applications, especially in field work. Quantifying parameters in the field requires both minimal sample handling and a device capable of performing measurements with high sensitivity and stability. Furthermore, the one-device-fits-all concept is useful for continuous monitoring of multiple parameters. Miniaturization of devices can be achieved by introducing graphene as part of the transducer in an electrochemical sensor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267983/synthesis-molecular-modeling-studies-and-anticonvulsant-activity-of-certain-1-benzyl-aryl-amino-cyclohexyl-methyl-esters
#15
Walaa Hamada Abd-Allah, Mona Elsayed Aboutabl, Mohamed Nabil Aboul-Enein, Aida Abdel Sattar El-Azzouny
A series of (1-(benzyl (aryl) amino) cyclohexyl) methyl esters 7a-n were prepared and screened for their anticonvulsant profile. Screening of these esters 7a-n and their starting alcohols 6a and 6b revealed that compound 7k was the most potent one in the scPTZ screening test with an ED50 value of 0.0056mmol/kg being about 10- and 164-fold more potent than phenobarbital (ED50=0.056mmol/kg) and ethosuximide (ED50=0.92mmol/kg) as reference drugs, respectively. Meanwhile, in the MES test, compounds 7b and 7k at doses 0...
February 27, 2017: Bioorganic Chemistry
https://www.readbyqxmd.com/read/28264260/-i-irene-litanga-i-a-new-genus-and-new-species-in-the-i-polia-i-generic-complex-from-china-lepidoptera-noctuidae-hadeninae-hadenini
#16
Aidas Saldaitis, Balázs Benedek
A new Hadenini genus and species, Irene gen. n. litanga sp. n. (Figs 1-4, 13, 15), are described from China. This is the third paper since 2013 dealing with members of the Polia-complex in the Himalayan region and particularly the mountainous areas of Central China (Saldaitis et al., 2013, 2016). The discovery of a new genus within the Polia genera group again demonstrates the fascinating and surprising diversity of the region. The clarification of the relationship between the genera-subgenera and species belonging to Polia genera group, (e...
March 2, 2017: Zootaxa
https://www.readbyqxmd.com/read/28259709/consensus-classification-of-posterior-cortical-atrophy
#17
Sebastian J Crutch, Jonathan M Schott, Gil D Rabinovici, Melissa Murray, Julie S Snowden, Wiesje M van der Flier, Bradford C Dickerson, Rik Vandenberghe, Samrah Ahmed, Thomas H Bak, Bradley F Boeve, Christopher Butler, Stefano F Cappa, Mathieu Ceccaldi, Leonardo Cruz de Souza, Bruno Dubois, Olivier Felician, Douglas Galasko, Jonathan Graff-Radford, Neill R Graff-Radford, Patrick R Hof, Pierre Krolak-Salmon, Manja Lehmann, Eloi Magnin, Mario F Mendez, Peter J Nestor, Chiadi U Onyike, Victoria S Pelak, Yolande Pijnenburg, Silvia Primativo, Martin N Rossor, Natalie S Ryan, Philip Scheltens, Timothy J Shakespeare, Aida Suárez González, David F Tang-Wai, Keir X X Yong, Maria Carrillo, Nick C Fox
INTRODUCTION: A classification framework for posterior cortical atrophy (PCA) is proposed to improve the uniformity of definition of the syndrome in a variety of research settings. METHODS: Consensus statements about PCA were developed through a detailed literature review, the formation of an international multidisciplinary working party which convened on four occasions, and a Web-based quantitative survey regarding symptom frequency and the conceptualization of PCA...
March 1, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/28258173/reducing-depressive-symptoms-after-the-great-east-japan-earthquake-in-older-survivors-through-group-exercise-participation-and-regular-walking-a-prospective-observational-study
#18
Taishi Tsuji, Yuri Sasaki, Yusuke Matsuyama, Yukihiro Sato, Jun Aida, Katsunori Kondo, Ichiro Kawachi
OBJECTIVES: Survivors of the 2011 Great East Japan Earthquake have an increased risk of depressive symptoms. We sought to examine whether participation in group exercise and regular walking could mitigate the worsening of depressive symptoms among older survivors. DESIGN: Prospective observational study. SETTING: Our baseline survey was conducted in August 2010, ∼7 months prior to the Great East Japan Earthquake and tsunami, among people aged 65 or older residing in Iwanuma City, Japan, which suffered significant damage in the disaster...
March 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28251432/impact-of-caries-and-dental-fluorosis-on-oral-health-related-quality-of-life-a-cross-sectional-study-in-schoolchildren-receiving-water-naturally-fluoridated-at-above-optimal-levels
#19
Álvaro García-Pérez, María Esther Irigoyen-Camacho, S Aída Borges-Yáñez, Marco Antonio Zepeda-Zepeda, Irvin Bolona-Gallardo, Gerardo Maupomé
PURPOSE: The purpose of this study was to evaluate the impact of caries and fluorosis on oral health-related quality of life (OHRQoL) among schoolchildren living in areas with high concentrations of fluoride in water. METHODS: Five hundred and twenty-four schoolchildren (8-12 year olds) residing in rural communities in central Mexico were examined for oral hygiene, caries (International Caries Detection and Assessment System, ICDAS II), and fluorosis (Thylstrup and Fejerskov Index, TFI)...
March 1, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28243606/optimization-of-hydrothermal-and-diluted-acid-pretreatments-of-tunisian-luffa-cylindrica-l-fibers-for-2g-bioethanol-production-through-the-cubic-central-composite-experimental-design-ccd-response-surface-methodology
#20
Kaouther Zaafouri, Manel Ziadi, Aida Ben Hassen-Trabelsi, Sabrine Mekni, Balkiss Aïssi, Marwen Alaya, Latifa Bergaoui, Moktar Hamdi
This paper opens up a new issue dealing with Luffa cylindrica (LC) lignocellulosic biomass recovery in order to produce 2G bioethanol. LC fibers are composed of three principal fractions, namely, α-cellulose (45.80%  ± 1.3), hemicelluloses (20.76%  ± 0.3), and lignins (13.15%  ± 0.6). The optimization of LC fibers hydrothermal and diluted acid pretreatments duration and temperature were achieved through the cubic central composite experimental design CCD. The pretreatments optimization was monitored via the determination of reducing sugars...
2017: BioMed Research International
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