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Junfeng Shi, Yi Chen, Yuetong Chen, Yunzhu Shen, Huanyu Zhao, Hui Sun, Jinfei Chen
RATIONALE: Cytotoxic T lymphocyte (CTL) immunotherapy is an autologous cellular immune therapy that has been approved for treating patients with malignant tumors. However, there is still limited information regarding the impact of CTL on metastatic prostate cancer (PC) patients with bone metastatic lesions. PATIENT CONCERNS: An 82-year-old male patient complained of interrupted urination, urination pain, and significant dysuria on November 24, 2014. Transurethral resection of the prostate (TURP) and postoperative pathological examination showed prostatic adenocarcinoma, and a SPECT/CT scan demonstrated multiple bone metastases...
June 2018: Medicine (Baltimore)
Veeru Kasivisvanathan, Muddassar Hussain
INTRODUCTION: The purpose of this analysis was to compare Aquablation to transurethral resection of the prostate (TURP) with respect to efficacy and safety at 1 year for the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia (BPH) in the United States (U.S.) cohort from the Waterjet Ablation Therapy for Endoscopic Resection of prostate tissue (WATER) study. MATERIALS AND METHODS: WATER is a double-blinded, multicenter prospective randomized controlled trial for patients with moderate-to-severe lower urinary tract symptoms related to BPH...
June 2018: Canadian Journal of Urology
Caifang Chen, Mingqiang Zeng, Ruizhi Xue, Guilin Wang, Zhiyong Gao, Wuxiong Yuan, Zhengyan Tang
To explore the etiology of male urethral stricture, analyze the therapeutic strategies of urethral stricture, and summarize the complicated cases.
 Methods: The data of 183 patients with urethral stricture were retrospectively analyzed, including etiology, obstruction site, stricture length, therapeutic strategy, and related complications.
 Results: The mean age was 49.7 years, the average course was 64.7 months, and the constituent ratio of 51 to 65 years old patients was 38.8% (71/183). The traumatic injury of patients accounted for 52...
May 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Shahnawaz Rajpar, Bilal Surya, Khalil Mobin, Santosh Kumar
To share the experience of 100 cases of Transurethral Resection of Prostate (TURP), This cross-sectional study was conducted in the Department of Urology, SMBBMC and Lyari General Hospital, Karachi from 1.1.13 to 30.4.15. One hundred cases were selected through purposive sampling. Patients who underwent TURP were included. Those with two life threatening co-morbidities, positive urine culture and patients on anti coagulant medications were excluded from the study. Mean age of the patients was 66±6.2 years with minimum 60 years and maximum 85 years...
May 2018: JPMA. the Journal of the Pakistan Medical Association
Joanie Pelletier, Sarah-Jeanne Cyr, Anne-Sophie Julien, Yves Fradet, Louis Lacombe, Paul Toren
BACKGROUND: Advanced prostate cancer may cause significant local complications which affect quality of life, including bladder outlet obstruction and hematuria. We performed a detailed review of our outcomes of palliative transurethral resection of the prostate (pTURP) in the era of taxane chemotherapy and potent androgen receptor antagonists at our tertiary-care institution. METHODS: Using hospital coding data, we identified patients with a diagnosis of prostate cancer who underwent a TURP at Hotel-Dieu Hospital in Quebec City between 2006 and 2016 for detailed chart review...
June 4, 2018: Urologic Oncology
Mark Plante, Peter Gilling, Neil Barber, Mohamed Bidair, Paul Anderson, Mark Sutton, Tev Aho, Eugene Kramolowsky, Andrew Thomas, Barrett Cowan, Ronald P Kaufman, Andrew Trainer, Andrew Arther, Gopal Badlani, Mihir Desai, Leo Doumanian, Alexis E Te, Mark DeGuenther, Claus Roehrborn
BACKGROUND: Aquablation, a waterjet-based prostate resection, has been used for the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia. The hypothesis that BPH surgery standardized with robotic execution may have a more pronounced benefit in certain subgroups such as subjects with more challenging anatomies (e.g., large prostates, large middle lobes) and subjects with moderate BPH has not yet been determined. METHODS: We conducted prespecified and post-hoc exploratory subgroup analyses from a double-blind, multicenter prospective randomized controlled trial comparing transurethral resection of the prostate using either standard electrocautery (TURP) or robotic waterjet (Aquablation) to determine whether certain baseline factors predicted more marked responses after Aquablation as compared to TURP...
June 4, 2018: BJU International
Bernd Rosenhammer, Eva M Lausenmeyer, Roman Mayr, Maximilian Burger, Christian Eichelberg
PURPOSE: Holmium laser enucleation of the prostate (HoLEP) has become a popular alternative to TURP for desobstructive prostate surgery. The prevalence of incidental prostate cancer (iPCa) during surgery varies depending on many preoperative factors. To evaluate whether the surgical procedure itself (HoLEP vs. TURP) influences iPCa detection, we performed a case-by-case matched-pair analysis. METHODS: Preoperative patient age, total PSA, and prostate volume were used as matching criteria...
June 1, 2018: World Journal of Urology
William C Fox, Richard E Moon
There have been many complications associated with transurethral resection of the prostate (TURP), known as TURP syndrome. Of the various irrigation fluids used for TURP, glycine irrigant has been historically popular given its relatively low cost. It is also a nonconductive solution and only slightly hypoosmolar, reducing the risk of burn injury or significant hemolysis. However, there have been many case reports of central nervous system toxicity such as transient blindness and encephalopathy related to glycine toxicity...
May 29, 2018: A&A practice
Michael Chao, Sandra Spencer, Mario Guerrieri, Wei Ding, Mehran Goharian, Huong Ho, Michael Ng, Danielle Healey, Alwin Tan, Chee Cham, Daryl Lim Joon, Nathan Lawrentschuk, Douglas Travis, Shomik Sengupta, Yee Chan, Andrew Troy, Trung Pham, David Clarke, Peter Liodakis, Damien Bolton
Purpose: To report the 5-year biochemical relapse-free survival (BRFS), overall survival (OS), and long-term toxicity outcomes of patients treated with low-dose-rate (LDR) brachytherapy as monotherapy for low- to intermediate-risk prostate cancer. Material and methods: Between 2004 and 2011, 371 patients were treated with LDR brachytherapy as monotherapy. Of these, 102 patients (27%) underwent transurethral resection of the prostate (TURP) prior to implantation...
April 2018: Journal of Contemporary Brachytherapy
Harris E Foster, Michael J Barry, Philipp Dahm, Manhar C Gandhi, Steven A Kaplan, Tobias S Kohler, Lori B Lerner, Deborah J Lightner, J Kellogg Parsons, Claus G Roehrborn, Charles Welliver, Timothy J Wilt, Kevin T McVary
Purpose; Male lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) is common in men and can have negative effects on quality of life (QOL). It is the hope that this Guideline becomes a reference on the effective evidence-based surgical management of LUTS/BPH. MATERIALS/METHODS: The evidence team searched Ovid MEDLINE, the Cochrane Library, and the Agency for Healthcare Research and Quality (AHRQ) database to identify studies indexed between January 2007 and September 2017...
May 15, 2018: Journal of Urology
Mario Petrillo, Filippo Pesapane, Enrico Maria Fumarola, Ilaria Emili, Marzia Acquasanta, Francesca Patella, Salvatore Alessio Angileri, Umberto G Rossi, Igor Piacentini, Antonio Maria Granata, Anna Maria Ierardi, Gianpaolo Carrafiello
Prostatectomy via open surgery or transurethral resection of the prostate (TURP) is the standard treatment for benign prostatic hyperplasia (BPH). Several patients present contraindication for standard approach, individuals older than 60 years with urinary tract infection, strictures, post-operative pain, incontinence or urinary retention, sexual dysfunction, and blood loss are not good candidates for surgery. Prostatic artery embolization (PAE) is emerging as a viable method for patients unsuitable for surgery...
April 2018: Gland Surgery
Richard Lee, Claus Roehrborn
Transurethral resection of the prostate (TURP) is considered the gold standard for minimally invasive treatment of lower urinary tract symptoms due to benign prostate enlargement of <80ml. Although durable and effective, TURP carries the risk of significant side effects, including infection and bleeding, and the risk of dilutional hyponatremia. The Aquabeam system uses high-velocity water jets to robotically ablate prostatic tissue under real-time ultrasound guidance, with hemostasis achieved via a catheter balloon tamponade and a novel traction device or electrocautery...
May 7, 2018: European Urology Focus
Hua-Jie Zhang, Guo-Sheng Yang
n recent years, photoselective vaporization of the prostate (PVP) has gained a wide clinical application in the treatment of benign prostatic hyperplasia (BPH) for its satisfactory effect, high safety, and low incidence of complications. With the improvement of living conditions, BPH patients are paying more attention to their sexual function, especially erectile function and ejaculatory problems instead of just focusing on the alleviation of lower urinary tract symptoms. Few studies of PVP, however, relate to its association with the sexual function of the patient and there is a certain controversy over the influence of PVP on it in the existing literature...
December 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
Wen Song, Tao Wang, Qing Ling, Xia-Ming Liu, Zhong Chen, Xiao-Dong Song, Xiao-Lin Guo, Qian-Yuan Zhuang, Shao-Gang Wang, Ji-Hong Liu
Objective: To compare thulium laser vaporization of the prostate (TLVP) and transurethral resection of the prostate (TURP) in the treatment of benign prostate hyperplasia (BPH) analyze the risk factors for postoperative urethral stricture. METHODS: From June 2015 to June 2016, 210 BPH patients in our hospital underwent TURP (n = 126) or TLVP (n = 84). We followed up the patients for 6 months, compared the effects of the two surgical strategies and analyzed the risk factors for postoperative urethral stricture by multivariate logistic regression analysis...
December 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
Klaus Eredics, David Wachabauer, Florian Röthlin, Stephan Madersbacher, Ingrid Schauer
OBJECTIVE: To assess long-term re-operation rates and mortality after transurethral resection of the prostate (TURP) and open prostatectomy (PE) as therapy for lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE). METHODS: Analysis of a nation-wide data base of all patients who underwent TURP/open PE 2002-2006 and who were followed for 8 years. Actuarial cumulative incidences of reoperation (TURP, urethrotomy, bladder neck incision) and death were calculated...
May 4, 2018: Urology
Sergio Hernando Mina, Herney Andres Garcia-Perdomo
Introduction: The objective of this study was to determine the effectiveness of tranexamic acid in decreasing bleeding in patients undergoing prostate surgery. Material and methods: All clinical experiments were included without language restrictions. The inclusion criteria were as follows: men over 18 years of age who underwent prostate surgery (transurethral, prostate adenectomy, and radical prostatectomy) and received tranexamic acid prior to prostate surgery as a preventive measure for perioperative hemorrhage...
2018: Central European Journal of Urology
Shi Li, Guang-Hai Yu
Objective: To sum up the experience in the treatment of prostate cancer found in transurethral resection of the prostate (TURP) by laparoscopic radical prostatectomy (LRP). METHODS: Fourteen patients found with prostate cancer during TURP underwent LRP in our hospital between 2011 and 2016. We reviewed our experience in the treatment and analyzed the clinical and follow-up data. RESULTS: LRP was successfully performed in all the cases at 1-4 months after TURP, with a mean operation time of (113 ± 94) min (80-220 min), a mean blood loss of (188 ± 152) ml (100-500 ml), a mean catheterization time of (11...
October 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
Jian-Liang Cai, Da Chen, Yu-Feng Song, Jing-Chao Han, Jing-Tian Xiao, Ning-Chen Li, Ming Xia, Yan-Qun Na
Objective: To study the dosage regimen of oral M-receptor blocker following transurethral resection of the prostate (TURP) for severe benign prostate hyperplasia (BPH) with predominant urine storage period symptoms (USPSs) and its clinical effect. METHODS: Severe BPH patients with predominant USPSs received oral tolterodine (2 mg q12d or 4 mg qd) 6 hours after TURP for 4 weeks. The medication continued for another 2 weeks in case of recurrence of USPSs or until the 12th week in case of repeated recurrence...
September 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
Rui Gao, Qi-Xiang Liu, Hui-Liang Zhou, Lin-Sheng Cao, Tao Jiang, Song-Xi Tang, Yi-Lang Ding
Objective: To investigate the expressions of interleukin-17 (IL-17) and interleukin-8 (IL-8) in benign prostatic hyperplasia (BPH) and BPH complicated with histological inflammation and their significance. METHODS: According to the results of HE staining, we divided 60 cases of BPH treated by transurethral resection of the prostate (TURP) into a BPH group (n = 23) and a BPH with inflammation group (n = 37). We analyzed the clinical data of the patients and determined the mRNA and protein expressions of IL-17 and IL-8 by immunohistochemistry, real-time fluorescence quantitative PCR, and Western blot, respectively...
August 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
Marco Dellabella, Alessandro Branchi, Luca Gasparri, Redi Claudini, Daniele Castellani
PURPOSE: To assess oncological safety and quality of life (QL) of men undergoing simultaneous transurethral resection of bladder tumor (TURBT) and transurethral resection of the prostate (TURP) for symptomatic benign prostatic hyperplasia (BPH). METHODS: Ninety-five men with a new diagnosis of bladder cancer (BC) and symptomatic BPH were randomized to receive TURBT + tamsulosin (Group 1) or TURBT + TURP (Group 2). Inclusion criteria were age ≤ 75 years, first diagnosis of BC up to 4 cm, and prostate volume ≤ 80 ml...
May 3, 2018: World Journal of Urology
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