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https://www.readbyqxmd.com/read/28537696/electron-microscopic-changes-of-detrusor-in-benign-enlargement-of-prostate-and-its-clinical-correlation
#1
Sher Singh Yadav, Rohit Bhattar, Lokesh Sharma, Gautam Banga, Trilok Chandra Sadasukhi
AIMS: To study the ultra structural changes in bladder musculature in cases of BPE and their clinical relevance. MATERIAL AND METHODS: In this descriptive longitudinal, controlled, observational study patients were enrolled into three groups, group 1, group 2A and group 2B. Control group (group-1) consisted of age matched normal male patients, who underwent surveillance or diagnostic cystoscopy for microscopic hematuria or irritative symptoms. Case group (group-2) comprised of patients with BPE, undergoing TURP...
May 23, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28516315/-finding-the-needle-in-a-haystack-oncologic-evaluation-of-patients-treated-for-luts-with-holmium-laser-enucleation-of-the-prostate-holep-versus-transurethral-resection-of-the-prostate-turp
#2
Annika Herlemann, Kerstin Wegner, Alexander Roosen, Alexander Buchner, Philipp Weinhold, Alexander Bachmann, Christian G Stief, Christian Gratzke, Giuseppe Magistro
PURPOSE: To evaluate oncologic parameters of men with bothersome LUTS undergoing surgical treatment with HoLEP or TURP. METHODS: Five hundred and eighteen patients undergoing HoLEP (n = 289) or TURP (n = 229) were retrospectively analyzed for total PSA, prostate volume, PSA density, history of prostate biopsy, resected prostate weight, and histopathological features. Univariate and multivariate logistic regression models were used to identify independent predictors of incidental PCa (iPCa)...
May 17, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28506859/the-obstructed-bladder-expression-of-collagen-matrix-metalloproteinases-muscarinic-receptors-angiogenic-and-neurotrophic-factors-in-patients-with-benign-prostatic-hyperplasia
#3
João Arthur Brunhara Alves Barbosa, Sabrina T Reis, Marco Nunes, Yuri A Ferreira, Katia R Leite, William C Nahas, Miguel Srougi, Alberto A Antunes
OBJECTIVE: to evaluate gene expression of Collagen, Matrix Metalloproteinases (MMP) and Inhibitors, Cholinergic Muscarinic Receptors (CHRM), Angiogenic and Nerve Growth Factors (NGF) in the bladder of patients with Bladder Outlet Obstruction due to Benign Prostatic Hyperplasia METHODS: We analyzed bladder specimens from 43 patients with obstructive BPH undergoing TURP as compared to 10 age-matched controls with IPSS<8 and prostate <30g. A bladder biopsy was performed for relative gene expression analysis with qRT-PCR of Collagens I and III, MMPs 1,2,9; Tissue Inhibitors of Metalloproteinases (TIMP) 1,2 and RECK; CHRM2 and -3; VEGF, CD105; NGF and NGF receptor...
May 12, 2017: Urology
https://www.readbyqxmd.com/read/28502962/treatment-results-of-transurethral-resection-of-the-prostate-by-non-japanese-board-certified-urologists-for-benign-prostate-hyperplasia-analysis-by-resection-volume
#4
Yasutomo Suzuki, Yuka Toyama, Satoko Nakayama, Shunichiro Nomura, Tadaaki Minowa, Kuniaki Tanabe, Yukihiro Kondo
INTRODUCTION: Transurethral resection of the prostate (TURP) is the gold standard for surgical treatment of benign prostatic hyperplasia (BPH), but it has complications such as bleeding and transurethral resection syndrome. The treatment results of TURP performed by non-Japanese board-certified urologists were examined, and the results were analyzed according to the resection volume to determine how much resection volume was suitable for non-Japanese board-certified urologists. MATERIALS AND METHODS: A total of 72 cases that underwent TURP for BPH at our hospital were examined...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28495071/perioperative-and-economic-analysis-of-surgical-treatments-for-benign-prostatic-hyperplasia-a-study-of-the-french-committee-on-lut
#5
R Mathieu, S Lebdai, J N Cornu, A Benchikh, A R Azzouzi, N B Delongchamps, O Dumonceau, A Faix, M Fourmarier, O Haillot, B Lukacs, V Misrai, A de La Taille, G Robert, A Descazeaud
PURPOSE: To evaluate perioperative cost related to surgical treatments of benign prostatic obstruction (BPO): photoselective vaporization of the prostate (pvp), holmium/thullium laser enucleation (HoLEP/ThuLEP), transurethral resection of the prostate (TURP) and open prostatectomy (OP). MATERIAL AND METHODS: We retrospectively collected data from 237 patients who consecutively underwent a surgical treatment for BPH between January 2012 and June 2013 at nine institutions in France...
May 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28480345/thulium-laser-vaporesection-of-the-prostate-can-we-operate-without-interrupting-oral-antiplatelet-anticoagulant-therapy
#6
Tarik Emre Sener, Salvatore Butticè, Luciano Macchione, Christopher Netsch, Yiloren Tanidir, Laurian Dragos, Rosa Pappalardo, Carlo Magno
PURPOSE: Thulium vaporesection of the prostate (ThuVARP) is a new and safe approach for patients receiving anticoagulant therapy in whom transurethral resection of the prostate (TURP) may possess a high bleeding risk. We aimed to demonstrate the efficacy and safety of ThuVARP in patients receiving oral antiplatelet/anticoagulant (OAP/OAC) therapy. MATERIALS AND METHODS: A total of 103 patients who underwent ThuVARP between 2011 and 2013 were enrolled in the study...
May 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28480344/urethral-strictures-after-bipolar-transurethral-resection-of-prostate-may-be-linked-to-slow-resection-rate
#7
Guan Hee Tan, Shamsul Azhar Shah, Nurayub Md Ali, Eng Hong Goh, Praveen Singam, Christopher Chee Kong Ho, Zulkifli Md Zainuddin
PURPOSE: This study aimed to determine the urethral stricture (US) rate and identify clinical and surgical risk factors associated with US occurrence after transurethral resection of the prostate using the bipolar Gyrus PlasmaKinetic Tissue Management System (PK-TURP). MATERIALS AND METHODS: This was an age-matched case-control study of US occurrence after PK-TURP. Retrospective data were collected from the hospital records of patients who had a minimum of 36 months of follow-up information...
May 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28479762/transurethral-resection-of-prostate-in-benign-prostatic-enlargement-with-underactive-bladder-a-retrospective-outcome-analysis
#8
Ashok Kumar Sokhal, Rahul Janak Sinha, Bimalesh Purkait, Vishwajeet Singh
PURPOSE: The purpose of this study was to evaluate the clinical outcome and efficacy of transurethral resection of the prostate in patients of benign prostatic enlargement (BPE) with underactive bladder. MATERIALS AND METHODS: Retrospective study of 174 patients, who underwent transurethral resection of prostate (TURP) between 2008 and 2015, for lower urinary tract symptoms with BPE with bladder underactivity. Clinical history, physical examination, renal function test, urinalysis, cystourethroscopy, transabdominal or transrectal ultrasonography, and urodynamic study were recorded...
April 2017: Urology Annals
https://www.readbyqxmd.com/read/28466803/intra-and-inter-rater-reliability-of-the-modified-ent-assessment-score-entas-2-in-granulomatosis-with-polyangiitis-a-prospective-randomised-trial
#9
Lars Decker, Lisa Türp, Christoph Borzikowsky, Martin Laudien
OBJECTIVES: Ears nose and throat (ENT) involvement is found on a substantial proportion of patients with granulomatosis with polyangiitis (GPA). Structured, reliable ENT assessment is essential in the management of GPA patients. It is the aim of this study to determine the repeatability (intra-rater reliability) and reproducibility (inter-rater reliability) of the ENT Assessment Score (ENTAS 2). METHODS: The ENTAS 2 built the fundament of the prospective randomized trial...
March 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28440263/suprapubic-cystostomy-versus-nonsuprapubic-cystostomy-during-monopolar-transurethral-resection-of-prostate-a-propensity-score-matched-analysis
#10
Run-Qi Guo, Yi-Sen Meng, Wei Yu, Kai Zhang, Ben Xu, Yun-Xiang Xiao, Shi-Liang Wu, Bai-Nian Pan
We aim to reassess the safety of the monopolar transurethral resection of the prostate (M-TURP) without suprapubic cystostomy at our institution over the past decade. This retrospective study was conducted in patients who underwent M-TURP at Peking University First Hospital between 2003 and 2013. A total of 1680 patients who had undergone M-TURP were identified, including 539 patients in the noncystostomy group and 1141 patients in the cystostomy group. After propensity score matching, the number of patients in each group was 456...
April 18, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28435905/transurethral-resection-of-the-prostate-bladder-explosion-and-hyponatremic-encephalopathy-a-rare-case-report-of-malpractice
#11
Giuseppe Vacchiano, Aldo Rocca, Rita Compagna, Anna Ginevra Immacolata Zamboli, Vera Cirillo, Lorenza Di Domenico, Veronica Di Nardo, Giuseppe Servillo, Bruno Amato
We present an original case report of a bladder explosion during a TURP intervention for benign prostatic hypertrophy, that was brought on by the absorption of about 5 liters of glycine 1.5% and then onset of a severe hyponatremia. The quick and inappropriate correction of this electrolyte imbalance led the onset of encephalopathy and the death of the patient. The authors discuss the pathogenesis of these uncommon diseases and, considering the most recent Italian Legislation, they highlight the importance to respect good clinical practice standards and guidelines to ensure the most appropriate treatments for the patient and remove any assumptions of medical liability...
January 2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28422535/comparison-between-normal-saline-and-ringer-s-acetate-in-bipolar-transurethral-resection-of-the-prostate
#12
Ehab Ahmed, Jacob Ingvar, Claes R Nyman, Ulf Norming, Emma Andersson, Robert G Hahn, Tim Fagerström
OBJECTIVE: The standard surgical treatment for benign prostatic hypertrophy (BPH) is transurethral resection of the prostate (TURP). The aim of this study was to compare normal saline (NS) (0.9% sodium chloride) and Ringer's acetate (RA) as irrigation fluid with regard to visibility, resection feasibility, coagulation and bleeding in bipolar TURP. MATERIALS AND METHODS: Twenty patients (mean age 70 years) who were diagnosed with BPH were recruited to the study. The first three 3 liter bags of irrigation fluid contained either NS or RA and were administered in a randomized fashion...
April 19, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28416260/late-genitourinary-toxicity-outcomes-in-300-prostate-cancer-patients-treated-with-dose-escalated-image-guided-intensity-modulated-radiotherapy
#13
K Byrne, G Hruby, A Kneebone, D Whalley, L Guo, P McCloud, T Eade
AIMS: To quantify and qualify late genitourinary toxicity in a cohort of patients with localised prostate cancer treated with image-guided intensity-modulated radiotherapy (IMRT) to doses ≥78 Gy. MATERIALS AND METHODS: The cohort consisted of 300 patients treated with definitive dose-escalated IMRT between 2007 and 2013. Ninety-seven patients received 78-80 Gy in 38 fractions, and 203 received 82-84 Gy in 40 fractions. International Prostate Symptoms Score (IPSS) and supplemental quality of life data were recorded at baseline, weekly during treatment and at follow-up...
April 14, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28412960/a-randomised-controlled-trial-to-determine-the-clinical-and-cost-effectiveness-of-thulium-laser-transurethral-vaporesection-of-the-prostate-thuvarp-versus-transurethral-resection-of-the-prostate-turp-in-the-national-health-service-nhs-the-unblocs-trial-a-study
#14
Jo Worthington, Hilary Taylor, Paul Abrams, Sara T Brookes, Nikki Cotterill, Sian M Noble, Tobias Page, K Satchi Swami, J Athene Lane, Hashim Hashim
BACKGROUND: Transurethral resection of the prostate (TURP) has been the standard operation for benign prostatic obstruction (BPO) for 40 years, with approximately 25,000 procedures performed annually, and has remained largely unchanged. It is generally a successful operation, but has well-documented risks for the patient. Thulium laser transurethral vaporesection of the prostate (ThuVARP) vaporises and resects the prostate using a surgical technique similar to TURP. The small amount of study data currently available suggests that ThuVARP may have certain advantages over TURP, including reduced blood loss and shorter hospital stay, earlier return to normal activities, and shorter duration of catheterisation...
April 17, 2017: Trials
https://www.readbyqxmd.com/read/28401579/mri-assessment-of-tissue-effects-after-180-w-xps-greenlight-laser-vaporization-of-the-prostate
#15
Romain Huet, Romain Mathieu, Tanguy Rohou, Benoit Peyronnet, Andrea Manunta, Gregory Verhoest, Karim Bensalah, Sebastien Vincendeau
BACKGROUND AND OBJECTIVE: Photoselective vaporization of the prostate (PVP) is an alternative to transurethral resection of the prostate (TURP) in the surgical management of Benign Prostate Obtruction (BPO), with a better hemostatic effect due to a coagulation depth of several millimeters. The objective of this study was to prospectively assess the tissue effects of PVP by Magnetic Resonance Imaging (MRI). MATERIALS AND METHODS: From December to February 2014, ten patients were included in a prospective study and underwent PVP performed by a single surgeon with the Greenlight™ laser 180-W XPS...
April 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28394903/5-alpha-reductase-inhibitor-therapy-postpones-urine-retention-and-prostate-surgery-in-patients-with-prostate-enlargement-and-a-maximum-uroflow-rate-of-less-than-15-ml-sec
#16
Wenhsu Lin, Shangsen Lee, Jengyuan Wu, Yuhung Kuo, Tengfu Hsieh
BACKGROUND: This study investigated the risk of transurethral resection of prostate (TURP) and acute urine retention (AUR) in relation to 5-alpha-reductase inhibitor (5ARI) therapy. METHODS: We identified 22,687 patients who were newly diagnosed with PE and low urinary tract symptoms (LUTS) between January 1, 2002 and December 31, 2011. We further classified study subjects who had moderate to severe LUTS and a maximum uroflow rate of less than 15ml/sec into three groups by their defined daily dose (DDD) of 5ARI used...
2017: PloS One
https://www.readbyqxmd.com/read/28392430/-prospective-evaluation-of-the-direct-costs-of-prostate-enucleation-by-the-holep-%C3%A2-laser-during-the-learning-curve-period
#17
M Roger, M Goris-Gbenou, A Guillermet, R Vial, N Cunin, J Tomas, L Bourgue, M Combe, J-G Lopez, C Combe
OBJECTIVE: Holmium laser enucleation of the prostate (HoLEP) has been shown to be effective in treating large prostates compared to prostate transurethral resection (TURP). There are no published data evaluating specifically the impact of the learning curve on the direct costs of HoLEP. The objective of this study was to evaluate the direct costs generated by the use of HoLEP laser during the learning curve period. METHOD: The costs of all medical devices (DM) and drugs used, pre- and post-operative parameters during surgery have been prospectively collected between March and October 2016...
April 6, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28387891/evaluation-of-the-postoperative-cognitive-dysfunction-in-elderly-patients-with-general-anesthesia
#18
Y-L Chi, Z-S Li, C-S Lin, Q Wang, Y-K Zhou
OBJECTIVE: The present study is aimed to study the neuron-specific enolase (NSE) and S100b proteins in the evaluation of postoperative cognitive dysfunction in elderly patients with general anesthesia. PATIENTS AND METHODS: A total of 142 aged patients, who were treated with transurethral resection of the prostate (TURP) surgery under general anesthesia with propofol from June 2014 to December 2015, were randomly divided into two groups. The experiment group was given scopolamine butylbromide by intramuscular injection before the operation, while the control group had no preoperative intramuscular injection...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28380287/scarification-in-sub-saharan-africa-social-skin-remedy-and-medical-import
#19
Roland Garve, Miriam Garve, Jens C Türp, Julius N Fobil, Christian G Meyer
Various forms of body modification may be observed in sub-Saharan Africa. Hypotheses and theories of scarification and tribal marking in sub-Saharan Africa are described, plus the procedure of scarification, examples from several African countries, assumed effects in prevention and treatment of diseases, and the medical risks resulting from unsterile manipulation.
April 5, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28368238/functional-outcomes-and-complications-following-b-turp-versus-holep-for-the-treatment-of-benign-prostatic-hyperplasia-a-review-of-the-literature-and-meta-analysis
#20
Xiaoqiang Qian, Hailong Liu, Ding Xu, Le Xu, Fang Huang, Wei He, Jun Qi, Yu Zhu, Danfeng Xu
OBJECTIVE: To conduct a systematic review and Meta-analysis of the literature on the efficacy and safety of B-TURP versus HoLEP for the treatment of benign prostatic hyperplasia (BPH) in terms of demographic and clinical baseline characteristics, peri-operative variables, and postoperative outcomes and complications. METHODS: Trials comparing B-TURP and HoLEP were identified systematically using Pubmed, Embase, CNKI, Web of Science and the Cochrane Library. Primary outcomes were the peak urinary flow rate (Qmax), post-void residual volume (PVR) and international prostate symptom score (IPSS)...
April 3, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
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