keyword
MENU ▼
Read by QxMD icon Read
search

TURB

keyword
https://www.readbyqxmd.com/read/29661592/monopolar-vs-bipolar-transurethral-resection-for-non-muscle-invasive-bladder-carcinoma-a-post-hoc-analysis-from-a-randomized-controlled-trial
#1
Esmee I M L Liem, Michael McCormack, Eddie S Y Chan, Yoshiyuki Matsui, Petrisor Geavlete, Young D Choi, Theo M de Reijke, Yasser Farahat, Brant A Inman, Jean J M C H de la Rosette, Seiji Naito
PURPOSE: Traditionally, transurethral resection of bladder tumors (TURB) is performed using monopolar technique. Bipolar resection has been postulated to reduce complications. In this study we compare safety and efficacy between monopolar TURB (mTURB) and bipolar TURB (bTURB) for patients with primary non-muscle invasive bladder cancer (NMIBC). MATERIALS AND METHODS: Data were obtained from an international multicenter randomized clinical trial that compared the use of white light cystoscopy with narrow band imaging-assisted TURB using the Olympus system between 2010 and 2014...
April 13, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29649830/healthcare-associated-infections-after-lower-urinary-tract-endoscopic-surgery-analysis-of-risk-factors-associated-microorganisms-and-patterns-of-antibiotic-resistance
#2
Raquel Sopeña-Sutil, José Medina-Polo, Juan Justo-Quintas, Javier Gil-Moradillo, Lucia Garcia-Gonzalez, Raúl Benítez-Sala, Manuel Alonso-Isa, Alba Lara-Isla, Angel Tejido-Sanchez
OBJECTIVES: To review the incidence of healthcare-associated infections/urinary tract infection (UTI), risk factors, microorganisms isolated and antibiotic resistances in patients who underwent lower urinary tract endoscopic surgery (LUTES) in a tertiary care hospital. METHODS: A prospective observational study was carried out including 1,498 patients who undergo LUTES. Patients with and without UTI after surgery were compared. We analysed infection incidence, risk factors, microorganisms isolated and antibiotic resistances...
April 12, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29580697/intravesical-recurrence-after-bladder-sparing-treatment-of-small-cell-carcinoma-of-the-bladder-characteristics-treatment-and-outcome
#3
Maaike van de Kamp, Richard Meijer, Floris Pos, Martijn Kerst, Eric van Werkhoven, Bas van Rhijn, Simon Horenblas, Axel Bex
INTRODUCTION: Small cell carcinoma of the bladder (SCCB) is a rare and lethal disease. Previously, we and others have reported a bladder sparing strategy with platinum-etoposide-based chemotherapy followed by radiotherapy of the bladder. Little is known on frequency and treatment of intravesical recurrence following this approach. The objective of this study is to describe the incidence of intravesical recurrences and their management. MATERIALS AND METHODS: Retrospective study including all patients with SCCB treated at a single institution from 1993 until 2016...
March 23, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29541583/treatment-experience-for-incidentally-diagnosed-asymptomatic-prostate-tuberculosis-in-a-patient-with-history-of-bcg-intravesical-therapy
#4
Suk Young Lee, Sang Hee Choi
Intravesical BCG therapy after transurethral resection of bladder tumor (TURB) is considered the most effective treatment for prophylaxis against the recurrence of high risk non-muscle invasive bladder cancer, and generally well tolerated and infectious complication are rare. We reported a case of granulomatous prostatitis is a patient who had undergone intravesical BCG therapy due to non-invasive superficial urothelial carcinoma of bladder. This patient was diagnosed by prostate biopsy because of PSA elevation without any other voiding symptoms and abnormal abscess pocket in transrectal ultrasonography...
March 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29528758/update-on-early-instillation-of-chemotherapy-after-transurethral-resection-of-non-muscle-invasive-bladder-cancer
#5
Willem Oosterlinck, Karel Decaestecker
Non-muscle-invasive bladder cancer (NMIBC) is a highly recurrent disease. Early bladder chemotherapy instillation (EBCI) after transurethral resection (TURB) is an efficient way to diminish recurrence. However, this method is often challenged. Areas covered: There was a recent publication of a large meta-analysis with the original patient data and the largest study ever on EBCI. Both brought new evidence on EBCI. Also the results of the 2 trials of EBCI with apaziquone appeared. EBCI is discussed among other methods to decrease recurrence...
May 2018: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29506941/accurate-prediction-of-progression-to-muscle-invasive-disease-in-patients-with-pt1g3-bladder-cancer-a-clinical-decision-making-tool
#6
David D Andrea, Mohammad Abufaraj, Martin Susani, Robin Ristl, Beat Foerster, Shoji Kimura, Andrea Mari, Francesco Soria, Alberto Briganti, Pierre I Karakiewicz, Killian M Gust, Morgan Rouprêt, Shahrokh F Shariat
PURPOSE: To improve current prognostic models for the selection of patients with T1G3 urothelial bladder cancer who are more likely to fail intravesical therapy and progress to muscle-invasive bladder cancer (MIBC). MATERIALS AND METHODS: We performed a retrospective analysis of 1,289 patients with pT1G3 urothelial bladder cancer who were treated with transurethral resection of the bladder (TURB) and adjuvant intravesical bacillus-Calmette-Guérin (BCG). Random-split sample data and competing-risk regression were used to identify the independent impact of lymphovascular invasion (LVI) and variant histology (VH) on progression to MIBC...
March 2, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29497859/transurethral-resection-of-bladder-cancer-on-the-lateral-bladder-wall-without-obturator-nerve-block-extent-of-adductor-spasms-using-the-monopolar-versus-bipolar-technique-a-prospective-randomised-study
#7
T Gramann, C Schwab, V Zumstein, P Betschart, M Meier, H-P Schmid, D S Engeler
PURPOSE: To establish whether bipolar transurethral resection of tumours (bTURB) on the lateral bladder wall is superior to monopolar transurethral resection (mTURB) of such tumours. To our knowledge, this is the first prospective randomised study, which defines complete resection depending on obturator jerk as primary endpoint. METHODS: In a prospective, randomised, single centre study, 52 patients with newly diagnosed or recurrent bladder tumour on the lateral bladder wall were enrolled and randomised to undergo mTURB or bTURB; 44 patients were eligible for analysis, of whom 21 underwent mTURB and 23 bTURB...
March 1, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29224022/bladder-fetal-rhabdomyoma-intermediate-type
#8
L González-Pérez, H Alvarez-Argüelles, V J Ramos Gutiérrez, S García Hernández, A C Plata Bello, T Concepción Masip, E Salido Ruiz
INTRODUCTION: Rhabdomyomas are benign tumors of striated muscle, the bladder localization is very rare. CLINICAL CASE: We present an 87-year-old male consulting for gross hematuria. Cystoscopy was done with evidence of bulged bladder mucosa in right side wall and dome. Post-transurethral resection of the bladder (TURB) pathological anatomy was negative for malignancy. As extension study abdominopelvic computed tomography was performed identifying a bladder thickening of right posterior sidewall and an increased density of the adjacent fat...
December 8, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29185633/-intravesical-microwave-thermo-chemotherapy-for-the-treatment-of-non-invasive-bladder-cancer
#9
Marek Benacka, Daniel A Benamran, Grégory Wirth, Christophe E Iselin
Non-invasive urothelial carcinoma of the bladder is known for its significant rate of recurrence after transurethral resection (TURB) even after adjuvant intravesical chemotherapy or immunoprophylaxis. Therefore, new and more effective approaches for the management of non-invasive bladder tumors have been developed and are progressively introduced in clinical practice. Recently, the endovesical administration of a combined regimen using a cytostatic agent and microwave-induced hyperthermia appears to be highly efficient and possibly superior to intravesical chemotherapy alone for none invasive bladder cancer...
November 29, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29152110/comparison-of-the-effect-of-spinal-anesthesia-and-general-anesthesia-on-5-year-tumor-recurrence-rates-after-transurethral-resection-of-bladder-tumors
#10
Woo-Jong Choi, Seunghee Baek, Eun-Young Joo, Syn-Hae Yoon, Eunkyul Kim, Bumsik Hong, Jai-Hyun Hwang, Young-Kug Kim
Non-muscle invasive bladder tumors are early-stage tumors with high recurrence rates. Transurethral resection of bladder tumor (TURB) is performed under spinal or general anesthesia; however, the effect of the two anesthetic techniques on non-muscle invasive bladder tumor recurrence is unknown. Thus, we compared their effects on tumor recurrence rates five years after TURB. Data from 876 patients who underwent TURB from 2000 to 2007 was reviewed. Patients received spinal or general anesthesia based on their choice or the clinician's preference...
October 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/29074050/discrepancy-between-european-association-of-urology-guidelines-and-daily-practice-in-the-management-of-non-muscle-invasive-bladder-cancer-results-of-a-european-survey
#11
Kees Hendricksen, Atiqullah Aziz, Perrine Bes, Felix K-H Chun, Jakub Dobruch, Luis A Kluth, Paolo Gontero, Andrea Necchi, Aidan P Noon, Bas W G van Rhijn, Michael Rink, Florian Roghmann, Morgan Rouprêt, Roland Seiler, Shahrokh F Shariat, Brian Qvick, Marek Babjuk, Evanguelos Xylinas
BACKGROUND: The European Association of Urology (EAU) non-muscle-invasive bladder cancer (NMIBC) guidelines are meant to help minimise morbidity and improve the care of patients with NMIBC. However, there may be underuse of guideline-recommended care in this potentially curable cohort. OBJECTIVE: To assess European physicians' current practice in the management of NMIBC and evaluate its concordance with the EAU 2013 guidelines. DESIGN, SETTING, AND PARTICIPANTS: Initial 45-min telephone interviews were conducted with 20 urologists to develop a 26-item questionnaire for a 30-min online quantitative interview...
October 23, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29034722/the-efficacy-of-apaziquone-in-the-treatment-of-bladder-cancer
#12
Francisco Caramés Masana, Theo M de Reijke
Bladder cancer is nowadays a common tumor. Non-muscle invasive bladder cancer (NMIBC) has still chances of recurrence and progression in spite of surgery and adjuvant treatments. New therapies are being developed to reduce these percentages with less adverse effects - Apaziquone (EO9) is an example. Areas covered: A literature search has been performed using Pubmed, UpToDate and Google verified information (mainly from Food and Drug Administration and Spectrum Pharmaceutics websites). We have included data from the most representative clinical trials and reviews published...
October 20, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28931860/towards-an-ultra-rapid-smartphone-connected-test-for-infectious-diseases
#13
Valérian Turbé, Eleanor R Gray, Victoria E Lawson, Eleni Nastouli, Jennifer C Brookes, Robin A Weiss, Deenan Pillay, Vincent C Emery, C Theo Verrips, Hiromi Yatsuda, Dale Athey, Rachel A McKendry
The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10 seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, is extremely fast because no complex labelling, amplification or wash steps are needed. A pocket-sized control box reads out the SAW signal and displays results electronically. High analytical sensitivity and specificity are found with model and real patient blood samples...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28866819/fluorescence-in-situ-hybridization-as-prognostic-predictor-of-tumor-recurrence-during-treatment-with-bacillus-calmette-gu%C3%A3-rin-therapy-for-intermediate-and-high-risk-non-muscle-invasive-bladder-cancer
#14
Esmee I M L Liem, Joyce Baard, Evelyne C C Cauberg, Mieke T J Bus, D Martijn de Bruin, M Pilar Laguna Pes, Jean J M C H de la Rosette, Theo M de Reijke
A significant number of patients with intermediate- or high-risk bladder cancer treated with intravesical Bacillus Calmette-Guérin (BCG) immunotherapy are non-responders to this treatment. Since we cannot predict in which patients BCG therapy will fail, markers for responders are needed. UroVysion(®) is a multitarget fluorescence in situ hybridization (FISH) test for bladder cancer detection. The aim of this study was to evaluate whether FISH can be used to early identify recurrence during treatment with BCG...
September 2, 2017: Medical Oncology
https://www.readbyqxmd.com/read/28851281/growth-phase-dependent-expression-profiles-of-three-vital-h-ns-family-proteins-encoded-on-the-chromosome-of-pseudomonas-putida-kt2440-and-on-the-pcar1-plasmid
#15
Zongping Sun, Delyana Vasileva, Chiho Suzuki-Minakuchi, Kazunori Okada, Feng Luo, Yasuo Igarashi, Hideaki Nojiri
BACKGROUND: H-NS family proteins are nucleoid-associated proteins that form oligomers on DNA and function as global regulators. They are found in both bacterial chromosomes and plasmids, and were suggested to be candidate effectors of the interaction between them. TurA and TurB are the predominantly expressed H-NS family proteins encoded on the chromosome of Pseudomonas putida KT2440, while Pmr is encoded on the carbazole-degradative incompatibility group P-7 plasmid pCAR1. Previous transcriptome analyses suggested that they function cooperatively, but play different roles in the global transcriptional network...
August 29, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28805264/large-nested-variant-of-urothelial-carcinoma-a%C3%A2-clinicopathological-study-of-36-cases
#16
Eva Compérat, Jesse K McKenney, Arndt Hartmann, Ondrej Hes, Simone Bertz, Justine Varinot, Fadi Brimo
AIMS: The large nested variant of urothelial carcinoma (LNUC) has been added to the World Health Organization (WHO) 2016 classification. Scant data exist, and little is known about its clinical behaviour. MATERIAL AND RESULTS: Cases fulfilling the morphological criteria of LNUC were collected. Pure and mixed cases (i.e. with other patterns of invasive UC) were studied. Immunohistochemical staining with cytokeratin (CK)7, p63, GATA-3, CK20, p53 and Ki-67 was performed...
June 9, 2017: Histopathology
https://www.readbyqxmd.com/read/28591513/unravelling-the-molecular-basis-of-high-affinity-nanobodies-against-hiv-p24-in-vitro-functional-structural-and-in-silico-insights
#17
Eleanor R Gray, Jennifer C Brookes, Christophe Caillat, Valérian Turbé, Benjamin L J Webb, Luke A Granger, Benjamin S Miller, Laura E McCoy, Mohamed El Khattabi, C Theo Verrips, Robin A Weiss, Dorothy M Duffy, Winfried Weissenhorn, Rachel A McKendry
Preventing the spread of infectious diseases remains an urgent priority worldwide, and this is driving the development of advanced nanotechnology to diagnose infections at the point of care. Herein, we report the creation of a library of novel nanobody capture ligands to detect p24, one of the earliest markers of HIV infection. We demonstrate that these nanobodies, one tenth the size of conventional antibodies, exhibit high sensitivity and broad specificity to global HIV-1 subtypes. Biophysical characterization indicates strong 690 pM binding constants and fast kinetic on-rates, 1 to 2 orders of magnitude better than monoclonal antibody comparators...
July 14, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/28480169/angiosarcoma-of-the-bladder-review-of-the-literature-and-discussion-about-a-clinical-case
#18
Florian Gerbaud, Alexandre Ingels, Sophie Ferlicot, Jacques Irani
Our reported case is a 72 year-old man who presented with hematuria. A transurethral resection of the bladder tumor (TURB-T) has been performed. Histopathological diagnosis was an epithelioid angiosarcoma. CT scan revealed a bladder thickening. The treatment consisted in a complete pelvectomy with urinary and digestive diversion. Following the operation, the patient developed liver and pulmonary metastasis. He died 5 months after the initial diagnosis.
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28461983/assessment-of-the-infiltrative-character-of-bladder-cancer-at-the-time-of-transurethral-resection-a-single-center-study
#19
Paweł Grzegółkowski, Krystian Kaczmarek, Artur Lemiński, Michał Soczawa, Adam Gołąb, Marcin Słojewski
INTRODUCTION: Determining the clinical stage of bladder carcinoma before radical cystectomy is characterized by a high inaccuracy rate. The discrepancy in some reports reaches up to 48%. Therefore intraoperative clinical staging of bladder carcinoma is not recommended before radical treatment as it is for prostate cancer. However, the accuracy of clinical assessment of the muscle invasive character of the tumors at the time of transurethral resection has not been studied. In our study we estimate the accuracy of clinical staging during endoscopic treatment...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28420564/prognostic-role-of-neutrophil-to-lymphocyte-ratio-in-primary-non-muscle-invasive-bladder-cancer
#20
David D'Andrea, Marco Moschini, Kilian Gust, Mohammad Abufaraj, Mehmet Özsoy, Romain Mathieu, Francesco Soria, Alberto Briganti, Morgan Rouprêt, Pierre I Karakiewicz, Shahrokh F Shariat
INTRODUCTION: The purpose of this study was to assess the role of pretreatment neutrophil-to-lymphocyte ratio (NLR) as a predictor of clinical outcomes in patients treated with transurethral resection (TURB) for primary non-muscle-invasive bladder cancer (NMIBC). PATIENTS AND METHODS: Data from 918 patients treated with TURB for primary NMIBC were retrospectively collected. NLR was evaluated as binary variable with the cut-point of 3 based on the visual best correlation of the receiver operating curve analyses focusing on disease recurrence...
March 27, 2017: Clinical Genitourinary Cancer
keyword
keyword
40904
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"