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Reconstructive urology

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https://www.readbyqxmd.com/read/29144932/re-radiation-induced-complex-anterior-urinary-fistulation-for-prostate-cancer-a-retrospective-multicenter-study-from-the-trauma-and-urologic-reconstruction-network-of-surgeons-turns
#1
https://www.readbyqxmd.com/read/29132797/cloaca-reconstruction-a-new-algorithm-which-considers-the-role-of-urethral-length-in-determining-surgical-planning
#2
Richard J Wood, Carlos A Reck-Burneo, Daniel Dajusta, Christina Ching, Rama Jayanthi, D Gregory Bates, Molly E Fuchs, Katherine McCracken, Geri Hewitt, Marc A Levitt
BACKGROUND: Cloacal malformations represent a uniquely complex challenge for surgeons. The surgical approach to date has been based on the common channel (CC) length with two patient groups considered: less than or greater than 3cm, which we believe is an oversimplification. We reviewed 19 patients, referred after surgery done elsewhere. Eight had postoperative urinary complications, 3 had constant urinary leakage and had been left after surgery with a urethra <1cm, .5 with an original 3 to 5cm common channel, who had undergone total urogenital mobilization (TUM), experienced peri-operative urethral loss needing a vesicostomy, and later, a Mitrofanoff...
October 12, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29118550/-horrendoplasty-a-case-of-total-perineal-destruction-by-agricultural-implement
#3
Pedro Simoes de Oliveira, Tiago Ribeiro de Oliveira, David Martinho, Francisco Martins
Although posterior urethral injury occurs almost always in association with pelvic fracture, it may result from severe trauma to the perineum with its associated potential lethality and severe morbidity. Early primary endoscopic realignment over a urethral catheter can be attempted, although an immediate suprapubic tube placement remains the standard of care. Definitive treatment consists of elective open posterior anastomotic urethroplasty through a perineal approach. The authors present a 53-year-old man who sustained total, massive perineal destruction resulting from work accident with an agricultural implement...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29071150/laparoendoscopic-single-site-surgery-for-the-treatment-of-different-urological-pathologies-defining-the-learning-curve-of-an-experienced-laparoscopist
#4
Aly M Abdel-Karim, Ibrahim M Elhenawy, Ahmed A Eid, Elsayed Yahia, Salah A Elsalmy
OBJECTIVES: To define the learning curve of laparoendoscopic single-site surgery (LESS) of an experienced laparoscopist. PATIENTS AND METHODS: Patients who had LESS, since its implementation in December 2009 until December 2014, were retrospectively analysed. Procedures were divided into groups of 10 and scored according to the European Scoring System for Laparoscopic Operations in Urology. Different LESS indications were done by one experienced laparoscopist. Technical feasibility, surgical safety, outcome, as well as the number of patients required to achieve professional competence were assessed...
September 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29046907/bladder-regeneration-in-a-canine-model-using-a-bladder-acellular-matrix-loaded-with-a-collagen-binding-bfgf
#5
Chunying Shi, Wei Chen, Bing Chen, Tao Shan, Weisheng Jia, Xianglin Hou, Longkun Li, Gang Ye, Jianwu Dai
Bladder reconstruction remains challenging for urological surgery due to lack of suitable regenerative scaffolds. In a previous study, we had used a collagen-binding basic fibroblast growth factor (CBD-bFGF) to bind bFGF to the collagen scaffold, which could promote bladder regeneration in rats. However, the limited graft size in rodent models cannot provide enough evidence to demonstrate the repair capabilities of this method for severely damaged bladders in humans or large animals. In this study, the CBD-bFGF was used to activate a bladder acellular matrix (BAM) scaffold, and the CBD-bFGF/BAM functional scaffold was assessed in a canine model with a large segment defect (half of the entire bladder was resected)...
October 19, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/29024555/concise-review-tissue-engineering-of-urinary-bladder-we-still-have-a-long-way-to-go
#6
REVIEW
Jan Adamowicz, Marta Pokrywczynska, Shane Vontelin Van Breda, Tomasz Kloskowski, Tomasz Drewa
Regenerative medicine is a new branch of medicine based on tissue engineering technology. This rapidly developing field of science offers revolutionary treatment strategy aimed at urinary bladder regeneration. Despite many promising announcements of experimental urinary bladder reconstruction, there has been a lack in commercialization of therapies based on current investigations. This is due to numerous obstacles that are slowly being identified and precisely overcome. The goal of this review is to present the current status of research on urinary bladder regeneration and highlight further challenges that need to be gradually addressed...
October 10, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29022780/primary-urethral-reconstruction-results-in-penile-fracture
#7
R Barros, Mis Silva, V Antonucci, L Schulze, L Koifman, L A Favorito
Objective This study assessed primary urethral reconstruction results in patients with a penile fracture. Materials and methods Between January 2005 and April 2016, patients who underwent primary urethral reconstruction due to penile fracture were called for a follow-up. Epidemiological and clinical presentation data and operative findings were reviewed retrospectively. Partial urethral lesions were primarily treated with interrupted absorbable sutures over urethral catheter. In cases of complete urethral lesion, tension-free end-to-end anastomosis was performed...
September 15, 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28976806/magnetic-compression-anastomosis-magnamosis-for-functional-undiversion-of-ileostomy-in-pediatric-patients
#8
Luzia Toselli, Marcelo Martinez-Ferro, Guillermo Cervio, Dillon Kwiat, Jill Imamura-Ching, Claire E Graves, Brandon Gaston, Michael Harrison
INTRODUCTION: Magnamosis forms a compression anastomosis using self-aligning magnetic Harrison rings. The device has been approved by the Food and Drug Administration for first-in-human testing and has been applied in adults for intestinal anastomosis during urologic reconstructions. We now report the first cases of magnamosis to functionally undivert the fecal stream from a previously created loop ileostomy in pediatric patients. MATERIALS AND METHODS: Case 1: A 4-year-old male underwent a diverting loop ileostomy for malignant bowel obstruction...
October 4, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28974870/preperitoneal-bladder-augmentation-feasibility-and-results
#9
Dhruva Nath Ghosh, Sampath Karl, Sudipta Sen
INTRODUCTION: Bladder augmentation is an important part of pediatric reconstructive urology. This study was conducted to assess the feasibility and results of our technique of preperitoneal bladder augmentation. MATERIALS AND METHODS: Thirty-three children underwent preperitoneal bladder augmentation for small inelastic bladders who had failed medical management or needed undiversion. The underlying diagnosis included neurogenic bladder, valve bladder, bladder exstrophy, non-neurogenic neurogenic, ectopic ureters, and urogenital sinus...
October 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28971794/bowel-preparation-prior-to-reconstructive-urologic-surgery-in-pediatric-myelomeningocele-patients
#10
Nicholas J Farber, Rachel B Davis, Gwen M Grimsby, Brian Shinder, Glenn M Cannon, Micah A Jacobs, Michael C Ost, Francis X Schneck, Heidi A Stephany, Patricio C Gargollo, Moira E Dwyer
INTRODUCTION: Mechanical bowel preparation (MBP) has historically been the standard of care for patients undergoing reconstructive urologic surgery, including urinary diversion. To date, several studies have examined the role of mechanical bowel preparation in postoperative outcomes in pediatric patients undergoing augmentation cystoplasty. However, these patient populations have been heterogeneous in nature, with no studies dedicated to examining the role of MBP prior to reconstructive urologic surgery in pediatric patients with myelomenginoceles...
October 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28965782/use-of-third-line-therapy-for-overactive-bladder-in-a-practice-with-multiple-subspecialty-providers-are-we-doing-enough
#11
Dena Moskowitz, Sarah A Adelstein, Alvaro Lucioni, Una J Lee, Kathleen C Kobashi
PURPOSE: Overactive bladder (OAB) impacts over 15% of the adult population. Compliance with medical treatment is low, due either to inadequate symptom control or intolerable side effects. Although third line therapies have improved the treatment of OAB, many patients do not receive optimal treatment. We hypothesize that the utilization of third line treatment is higher among female pelvic medicine and reconstructive surgery urologists and examine its use in our tertiary referral center...
September 28, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28964781/multicenter-analysis-of-patient-reported-outcomes-following-artificial-urinary-sphincter-placement-for-male-stress-urinary-incontinence
#12
Jonathan T Wingate, Bradley A Erickson, Gregory Murphy, Thomas G Smith, Benjamin N Breyer, Bryan B Voelzke
PURPOSE: Patient-centered data regarding functional and quality of life improvements after AUS placement is lacking. We analyzed the degree of benefit from AUS placement utilizing the ISI, a validated patient reported outcome measure assessing severity and bother of urinary incontinence and the IIQ-7, a validated patient reported outcome measure assessing the impact and emotional distress of urinary incontinence. MATERIALS AND METHODS: We performed a retrospective review from four participating centers in the Trauma and Urologic Reconstruction Network of Surgeons...
September 27, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28926122/stem-cells-and-differentiated-cells-differ-in-their-sensitivity-to-urine-in-vitro
#13
Marta Pokrywczyńska, Tomasz Kloskowski, Daria Balcerczyk, Monika Buhl, Arkadiusz Jundziłł, Maciej Nowacki, Kaja Męcińska-Jundziłł, Tomasz Drewa
INTRODUCTION: Urinary tract regeneration using tissue engineering is one of the most challenging issues in the field of reconstructive urology. Cells seeded on scaffold are exposed to urine immediately after the implantation. The outcome of urinary bladder regeneration is depended on the ability of these cells to survive, proliferate and regenerate. The aim of this study was to compare a sensitivity of three different cell lines to urine in vitro. MATERIAL AND METHODS: Three different cell lines were isolated from porcine bladder (urothelial cells, UCs and smooth muscle cells, SMCs) and adipose tissue (adipose-derived stem cells, ADSCs)...
September 19, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28917602/comparing-inpatient-versus-outpatient-bowel-preparation-in-children-and-adolescents-undergoing-appendicovesicostomy
#14
David L Weatherly, Konrad M Szymanski, Benjamin M Whittam, William E Bennett, Shelly King, Rosalia Misseri, Martin Kaefer, Richard C Rink, Mark P Cain
PURPOSE: The need for mechanical inpatient bowel preparation (IBP) in reconstructive pediatric urology has come under scrutiny, secondary to literature demonstrating little benefit regarding outcomes. Starting in 2013, a majority of patients undergoing reconstructive procedures at our institution no longer underwent IBP. We hypothesized that outpatient bowel preparation (OBP) would reduce length of stay (LOS) without increasing postoperative complications after appendicovesicostomy surgery...
August 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28887865/plasma-rich-plasma-the-ultimate-secret-for-youthful-skin-elixir-and-hair-growth-triggering
#15
REVIEW
Ebtisam Elghblawi
The clinical application of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors that are released from alpha-granule of the concentrated platelets and in the secretion of proteins which are able to capitalize on the healing process at the cellular level. It has been invented to restore the natural beauty by starting the natural rejuvenation process of the skin and aiming to make it function as a younger one and to keep the skin youthful and maintain it. Besides that, it is also emerged to include hairs as a new injectable procedure to enable stimulating hair growth locally and topically; preventing its fall; improving hair shaft, hair stem, and its caliber; increasing its shine, vitality, and pliability; and declining hair splitting and breakage...
September 8, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28886046/effects-of-water-avoidance-stress-on-peripheral-and-central-responses-during-bladder-filling-in-the-rat-a-multidisciplinary-approach-to-the-study-of-urologic-chronic-pelvic-pain-syndrome-mapp-research-network-study
#16
Zhuo Wang, Harriet H Chang, Yunliang Gao, Rong Zhang, Yumei Guo, Daniel P Holschneider, Larissa V Rodriguez
Stress plays a role in the exacerbation and possibly the development of functional lower urinary tract disorders. Chronic water avoidance stress (WAS) in rodents is a model with high construct and face validity to bladder hypersensitive syndromes, such as interstitial cystitis/bladder pain syndrome (IC/BPS), characterized by urinary frequency and bladder hyperalgesia and heightened stress responsiveness. Given the overlap of the brain circuits involved in stress, anxiety, and micturition, we evaluated the effects chronic stress has on bladder function, as well as its effects on regional brain activation during bladder filling...
2017: PloS One
https://www.readbyqxmd.com/read/28865709/minilaparoscopy-in-urology-systematic-review
#17
A Pérez-Lanzac, R García-Baquero
CONTEXT: There has been a boom in recent years in urological procedures using minilaparoscopy (ML). OBJECTIVE: To conduct a systematic review of the published evidence on ML and its current role in urology. ACQUISITION OF EVIDENCE: We performed a search on MedLine spanning October 1983 to December 2016 according to PRISMA criteria. A total of 6 comparative articles and 13 series were selected for this manuscript. SUMMARY OF THE EVIDENCE: Only 1 study was randomised, 4 studies were prospective and comparative, and most were case series in which the operations were performed with 3-mm instruments...
August 30, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28825970/managing-mid-and-lower-ureteral-benign-strictures-the-laparoscopic-way
#18
Bastab Ghosh, Pritesh Jain, Dilip Kumar Pal
OBJECTIVE: The aim of this study is to assess etiopathogenesis of ureteral mid/lower benign strictures and outcomes of various methods of laparoscopic reconstruction and repair. MATERIALS AND METHODS: We retrospectively reviewed the data of patients who underwent laparoscopic repair for mid and lower ureteral benign strictures at our department from January 2013 to February 2016. The demographic, operative, complication, and outcome data were analyzed. RESULTS: Twenty-two patients were treated by various methods of laparoscopic reconstruction in the department of urology for benign ureteral strictures...
August 21, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28811169/tissue-engineered-extracellular-matrices-ecms-in-urology-evolution-and-future-directions
#19
REVIEW
N F Davis, E M Cunnane, F J O'Brien, J J Mulvihill, M T Walsh
Autologous gastrointestinal tissue has remained the gold-standard reconstructive biomaterial in urology for >100 years. Mucus-secreting epithelium is associated with lifelong metabolic and neuromechanical complications when implanted into the urinary tract. Therefore, the availability of biocompatible tissue-engineered biomaterials such as extracellular matrix (ECM) scaffolds may provide an attractive alternative for urologists. ECMs are decellularised, biodegradable membranes that have shown promise for repairing defective urinary tract segments in vitro and in vivo by inducing a host-derived tissue remodelling response after implantation...
August 12, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28802569/gender-and-subspecialty-of-urology-faculty-in-department-based-leadership-roles
#20
Julia Han, Stephanie Stillings, Harold Hamann, Russell Terry, Louis Moy
OBJECTIVE: To characterize the current gender and subspecialty of those holding academic departmental administrative and educational leadership roles in urology. METHODS: We conducted a cross-sectional observational study of U.S. Urology Residency Programs in 2016-2017. Inclusion criteria were participation in the Urology Residency Match Program and having a department of urology website. From June 1, 2016 to August 20, 2016, each department's website was queried...
August 9, 2017: Urology
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