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deep brain stimulation depression

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https://www.readbyqxmd.com/read/27900544/gamma-knife-subcaudate-tractotomy-for-treatment-resistant-depression-and-target-characteristics-a-case-report-and-review
#1
Seong-Cheol Park, Jung Kyo Lee, Chan-Hyung Kim, Jin Pyo Hong, Do Hee Lee
Stereotactic subcaudate tractotomy has previously been suggested to be an effective treatment for depression. This is the first study to report the use of gamma-knife subcaudate tractotomy for treatment-resistant depression. A 49-year-old woman with major depressive disorder had been treated for 30 years, with nine suicide attempts during that time. The right and left target maximum diameter was 11 mm within 50 % isodose lines. The target was located more posteriorly and inferiorly than the subgenual cingulate target typically used for deep-brain stimulation...
November 29, 2016: Acta Neurochirurgica
https://www.readbyqxmd.com/read/27872807/identification-of-the-stria-medullaris-thalami-using-diffusion-tensor-imaging
#2
Ryan B Kochanski, Robert Dawe, Daniel B Eddelman, Mehmet Kocak, Sepehr Sani
BACKGROUND: Deep brain stimulation (DBS) via anatomical targeting of white matter tracts defined by diffusion tensor imaging (DTI) may be a useful tool in the treatment of pathologic neurophysiologic circuits implicated in certain disease states like treatment resistant depression (TRD). We sought to determine if DTI could be used to define the stria medullaris thalami (SM), the major afferent white matter pathway to the lateral habenula (LHb), a thalamic nucleus implicated in the pathophysiology of TRD...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27842519/administration-of-electroconvulsive-therapy-for-depression-associated-with-deep-brain-stimulation-in-a-patient-with-post-traumatic-parkinson-s-disease-a-case-study
#3
Miles G Cunningham, Golnaz Yadollahikhales, Gordana Vitaliano, Craig van Horne
BACKGROUND: Deep brain stimulation (DBS) has been shown to be effective for parkinsonian symptoms poorly responsive to medications. DBS is typically well-tolerated, as are the maintenance battery changes. Here we describe an adverse event during a battery replacement procedure that caused rapid onset of severe depression. CASE PRESENTATION: The patient is a 58-year-old woman who was in a serious motor vehicle accident and sustained a concussion with loss of consciousness...
November 15, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27812715/commentary-on-deep-brain-stimulation-for-treatment-refractory-depression
#4
Kathleen Mary Patchan
No abstract text is available yet for this article.
November 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27812714/deep-brain-stimulation-for-treatment-refractory-depression
#5
Puneet Narang, Amber Retzlaff, Kanwarjeet Brar, Steven Lippmann
Depression has a high lifetime prevalence and recurrence rate, with more than one-third of affected patients experiencing treatment-refractory depression. These individuals should benefit from additional treatment options such as deep brain stimulation (DBS), a research-grade intervention. DBS is being investigated for its efficacy in treatment-refractory cases. We reviewed the English-language literature published between the years 2010 and 2015 regarding the utility of DBS for patients with treatment-refractory depression...
November 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27768049/treating-clinical-depression-with-repetitive-deep-transcranial-magnetic-stimulation-using-the-brainsway-h1-coil
#6
David Feifel, Katherine Pappas
Repetitive transcranial magnetic stimulation (rTMS) is an emerging non-pharmacological approach to treating many brain-based disorders. rTMS uses electromagnetic coils to stimulate areas of the brain non-invasively. Deep transcranial magnetic stimulation (dTMS) with the Brainsway H1-coil system specifically is a type of rTMS indicated for treating patients with major depressive disorder (MDD) who are resistant to medication. The unique H1-coil design of this device is able to stimulate neuronal pathways that lie deeper in the targeted brain areas than those reached by conventional rTMS coils...
October 4, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27756252/disappearance-of-treatment-resistant-depression-after-damage-to-the-orbitofrontal-cortex-and-subgenual-cingulate-area-a-case-study
#7
Michitaka Funayama, Motoichiro Kato, Masaru Mimura
BACKGROUND: Although post-stroke depression is a well-characterized disorder, there is less understanding of how pre-existence of depression is affected by a stroke. CASE PRESENTATION: We describe a patient with treatment-resistant major depression, which had been ongoing for 14 years but disappeared shortly after onset of a subarachnoid hemorrhage. Her cognitive function and functional status were mostly unaffected by the stroke. However, she no longer excessively regretted past events...
October 19, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27753157/neuropsychological-outcomes-from-constant-current-deep-brain-stimulation-for-parkinson-s-disease
#8
Alexander I Tröster, Joseph Jankovic, Michele Tagliati, DeLea Peichel, Michael S Okun
OBJECTIVE: The aim of this study was to evaluate the neurobehavioral safety of constant-current subthalamic deep brain stimulation and to compare the neuropsychological effects of stimulation versus electrode placement alone. METHODS: A total of 136 patients with Parkinson's disease underwent bilateral subthalamic device implantation in this randomized trial. Patients received stimulation either immediately after device implantation (n = 101; active stimulation) or beginning 3 months after surgery (n = 35; delayed activation control)...
October 18, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/27743900/stimulation-of-subgenual-cingulate-area-decreases-limbic-top-down-effect-on-ventral-visual-stream-a-dbs-eeg-pilot-study
#9
Astrid Kibleur, Mircea Polosan, Pauline Favre, David Rudrauf, Thierry Bougerol, Stéphan Chabardès, Olivier David
Deep brain stimulation (DBS) of the subgenual cingulate gyrus (area CG25) is beneficial in treatment resistant depression. Though the mechanisms of action of Cg25 DBS remain largely unknown, it is commonly believed that Cg25 DBS modulates limbic activity of large networks to achieve thymic regulation of patients. To investigate how emotional attention is influenced by Cg25 DBS, we assessed behavioral and electroencephalographic (EEG) responses to an emotional Stroop task in 5 patients during ON and OFF stimulation conditions...
October 12, 2016: NeuroImage
https://www.readbyqxmd.com/read/27698736/use-of-deep-brain-stimulation-for-major-affective-disorders
#10
Kuanqing Mi
The multifactorial etiology of major affective disorders, such as major depression and bipolar disorder, poses a challenge for identification of effective treatments. In a substantial number of patients, psychopharmacologic treatment does not lead to effective continuous symptom relief. The use of deep brain stimulation (DBS) for treatment-resistant patients is an investigational approach that has recently produced promising results. The recent development of safer stereotaxic neurosurgery, and the combination with functional neuroimaging to map the affected brain circuits, have led to the investigation of DBS as a potential strategy to treat major mood disorders...
October 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27659923/cognitive-outcome-after-ventral-capsule-ventral-striatum-stimulation-for-treatment-resistant-major-depression
#11
Cynthia S Kubu, Tim Brelje, Meryl A Butters, Thilo Deckersbach, Paul Malloy, Paul Moberg, Alexander I Tröster, Eric Williamson, Gordon H Baltuch, Mahendra T Bhati, Linda L Carpenter, Darin D Dougherty, Robert H Howland, Ali R Rezai, Donald A Malone
BACKGROUND: We report the neuropsychological outcome of 25 patients with treatment-resistant major depressive disorder (TRD) who participated in an Institutional Review Board (IRB)-approved randomised double-blind trial comparing active to sham deep brain stimulation (DBS) in the anterior limb of the ventral capsule/ventral striatum (VC/VS). METHODS: Participants were randomised to active (n=12) versus sham (n=13) DBS for 16 weeks. Data were analysed at the individual and group levels...
September 22, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27644164/cellular-and-molecular-mechanisms-triggered-by-deep-brain-stimulation-in-depression-a-preclinical-and-clinical-approach
#12
REVIEW
S Torres-Sanchez, L Perez-Caballero, E Berrocoso
Deep Brain Stimulation (DBS) was originally developed as a therapeutic approach to manage movement disorders, in particular Parkinson's Disease. However, DBS also seems to be an effective treatment against refractory depression when patients fail to respond satisfactorily to conventional therapies. Thus, DBS targeting specific brain areas can produce an antidepressant response that improves depressive symptomatology, these areas including the subcallosal cingulate region, nucleus accumbens, ventral capsule/ventral striatum, medial forebrain bundle, the inferior thalamic peduncle and lateral habenula...
February 6, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/27642815/effectiveness-and-adverse-effects-of-deep-brain-stimulation-umbrella-review-of-meta-analyses
#13
Panagiotis N Papageorgiou, James Deschner, Spyridon N Papageorgiou
Background This umbrella review summarizes the evidence across meta-analyses regarding the effectiveness and adverse effects of deep brain stimulation (DBS). Methods Databases were searched up to March 2015 for meta-analyses of comparative trials in humans assessing the effectiveness or adverse effects of DBS. Data selection, data extraction, and risk of bias assessment were performed by two independent reviewers. Results Seven eligible systematic reviews were included assessing the use of DBS for epilepsy (n = 1), obsessive-compulsive disorder (n = 1), and Parkinson disease (n = 5)...
September 19, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27634495/schizophrenia-and-neurosurgery-a-dark-past-with-hope-of-a-brighter-future
#14
Prateek Agarwal, Christina E Sarris, Yehuda Herschman, Nitin Agarwal, Antonios Mammis
Schizophrenia is a chronic and progressive psychiatric disease that remains difficult to manage in the 21st century. Current medical therapies have been able to give reprieve and decrease incidence of psychotic episodes. However, as the disease progresses, patients can become ever more refractory to current pharmaceutical agents and the polypharmacy that is attempted in treatment. Additionally, many of these drugs have significant adverse effects, leaving the practitioner in a difficult predicament for treating these patients...
September 12, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27615170/-astroglial-modulation-of-deep-brain-stimulation-in-depression
#15
Adeline Etiévant, Guillaume Lucas, Nasser Haddjeri
No abstract text is available yet for this article.
August 2016: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/27601183/deep-transcranial-magnetic-stimulation-dtms-beyond-depression
#16
Aron Tendler, Noam Barnea Ygael, Yiftach Roth, Abraham Zangen
Deep transcranial magnetic stimulation (dTMS) utilizes different H-coils to study and treat a variety of psychiatric and neurological conditions with identifiable brain targets. The availability of this technology is dramatically changing the practice of psychiatry and neurology as it provides a safe and effective way to treat even drug-resistant patients. However, up until now, no effort was made to summarize the different types of H-coils that are available, and the conditions for which they were tested. Areas covered: Here we assembled all peer reviewed publication that used one of the H-coils, together with illustrations of the effective field they generate within the brain...
October 2016: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/27583182/the-pros-and-cons-of-intraoperative-ct-scan-in-evaluation-of-deep-brain-stimulation-lead-implantation-a-retrospective-study
#17
Domenico Servello, Edvin Zekaj, Christian Saleh, Claudio Pacchetti, Mauro Porta
BACKGROUND: Deep brain stimulation (DBS) is an established therapy for movement disorders, such as Parkinson's disease (PD), dystonia, and tremor. The efficacy of DBS depends on the correct lead positioning. The commonly adopted postoperative radiological evaluation is performed with computed tomography (CT) scan and/or magnetic resonance imaging (MRI). METHODS: We conducted a retrospective study on 202 patients who underwent DBS from January 2009 to October 2013...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27551867/-not-available
#18
Matilda Naesström, Patric Blomstedt, Owe Bodlund
Deep brain stimulation for psychiatric disorders Deep brain stimulation is an established treatment for movement disorders. It has been proven to be a safe method; only minor complications have been reported in larger studies. New indications for deep brain stimulation are under investigation; among them major depressive disorder and obsessive-compulsive disorder. Deep brain stimulation for severe and therapy-resistant major depressive disorder and obsessive compulsive-disorder shows promising results. However, the experience of deep brain stimulation in psychiatric disorders is limited...
2016: Läkartidningen
https://www.readbyqxmd.com/read/27527822/translating-the-habenula-from-rodents-to-humans
#19
Laura-Joy Boulos, Emmanuel Darcq, Brigitte Lina Kieffer
The habenula (Hb) is a central structure connecting forebrain to midbrain regions. This microstructure regulates monoaminergic systems, notably dopamine and serotonin, and integrates cognitive with emotional and sensory processing. Early preclinical data have described Hb as a brain nucleus activated in anticipation of aversive outcomes. Evidence has now accumulated to show that the Hb encodes both rewarding and aversive aspects of external stimuli, thus driving motivated behaviors and decision making. Human Hb research is still nascent but develops rapidly, alongside with the growth of neuroimaging and deep brain stimulation techniques...
June 7, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/27524960/longitudinal-changes-in-depressive-circuitry-in-response-to-neuromodulation-therapy
#20
Yagna Pathak, Oludamilola Salami, Sylvain Baillet, Zhimin Li, Christopher R Butson
BACKGROUND: Major depressive disorder (MDD) is a public health problem worldwide. There is increasing interest in using non-invasive therapies such as repetitive transcranial magnetic stimulation (rTMS) to treat MDD. However, the changes induced by rTMS on neural circuits remain poorly characterized. The present study aims to test whether the brain regions previously targeted by deep brain stimulation (DBS) in the treatment of MDD respond to rTMS, and whether functional connectivity (FC) measures can predict clinical response...
2016: Frontiers in Neural Circuits
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