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https://www.readbyqxmd.com/read/27933018/a-study-of-the-coupling-of-fet-temperament-traits-with-major-depression
#1
Irina N Trofimova, William Sulis
Objective: Temperament and mental illness have been linked to the same systems of behavioral regulation. A temperament model, carefully structured to respond to subtle differences within systems of behavior regulation, should exhibit distinct temperament patterns in the presence of mental illness. Previous comparisons of temperament profiles in mental disorders used mostly emotionality-related traits. In contrast, the Functional Ensemble of Temperament (FET) model differentiates not only between emotionality traits, but also between traits related to physical, verbal, and mental aspects of behavior and maps 12 functional aspects of behavior to temperament traits as well as to symptoms of mental illnesses...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27930698/major-depression-as-a-complex-dynamic-system
#2
Angélique O J Cramer, Claudia D van Borkulo, Erik J Giltay, Han L J van der Maas, Kenneth S Kendler, Marten Scheffer, Denny Borsboom
In this paper, we characterize major depression (MD) as a complex dynamic system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be characterized by their own network with unique architecture and resulting dynamics. With respect to architecture, we show that individuals vulnerable to developing MD are those with strong connections between symptoms: e.g., only one night of poor sleep suffices to make a particular person feel tired...
2016: PloS One
https://www.readbyqxmd.com/read/27927175/a-pilot-randomized-controlled-trial-of-a-tailored-cognitive-behavioural-therapy-based-intervention-for-depressive-symptoms-in-those-newly-diagnosed-with-multiple-sclerosis
#3
Litza A Kiropoulos, Trevor Kilpatrick, Alex Holmes, Jennifer Threader
BACKGROUND: To examine the effectiveness and acceptability of an 8-week individual tailored cognitive behavioural therapy (CBT) intervention for the treatment of depressive symptoms in those newly diagnosed with multiple sclerosis. METHODS: The current study presents a pilot, parallel group randomized controlled trial (RCT) with an allocation ratio of 1:1 conducted in a large research and teaching hospital in Melbourne, Australia. 30 individuals with a mean age of 36...
December 7, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27926440/fatigue-with-up-vs-downregulated-brain-arousal-should-not-be-confused
#4
U Hegerl, C Ulke
Fatigue is considered to be an important and frequent factor in motivation problems. However, this term lacks clinical and pathophysiological validity. Semantic precision has to be improved. Lack of drive and tiredness with increased sleepiness as observed in fatigue in the context of inflammatory and immunological processes (hypoaroused fatigue) has to be separated from inhibition of drive and tiredness with prolonged sleep onset latency as observed in major depression (hyperaroused fatigue). Subjective experiences as reported by patients, as well as clinical, behavioral, and neurobiological findings support the validity and importance of this distinction...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/27925450/stress-inflammation-and-pain-a-potential-role-for-monocytes-in-fibromyalgia-related-symptom-severity
#5
Ann Gill Taylor, Tamara G Fischer-White, Joel G Anderson, Katharine E Adelstein, Maheswari Murugesan, Janet E Lewis, Michael M Scott, Ronald P A Gaykema, Lisa E Goehler
The possibility that immunological changes might contribute to symptom severity in fibromyalgia (FM) prompted this proof-of-concept study to determine whether differences in monocyte subpopulations might be present in persons with FM compared with healthy controls. Relationships were assessed by comparing specific symptoms in those with FM (n = 20) and patterns of monocyte subpopulations with healthy age-matched and gender-matched controls (n = 20). Within the same time frame, all participants provided a blood sample and completed measures related to pain, fatigue, sleep disturbances, perceived stress, positive and negative affect and depressed mood (and the Fibromyalgia Impact Questionnaire for those with FM)...
December 2016: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/27924137/exercise-induced-stress-behavior-gut-microbiota-brain-axis-and-diet-a-systematic-review-for-athletes
#6
REVIEW
Allison Clark, Núria Mach
Fatigue, mood disturbances, under performance and gastrointestinal distress are common among athletes during training and competition. The psychosocial and physical demands during intense exercise can initiate a stress response activating the sympathetic-adrenomedullary and hypothalamus-pituitary-adrenal (HPA) axes, resulting in the release of stress and catabolic hormones, inflammatory cytokines and microbial molecules. The gut is home to trillions of microorganisms that have fundamental roles in many aspects of human biology, including metabolism, endocrine, neuronal and immune function...
2016: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/27923434/listening-to-the-patient-voice-in-narcolepsy-diagnostic-delay-disease-burden-and-treatment-efficacy
#7
Kiran Maski, Erin Steinhart, David Williams, Thomas Scammell, Julie Flygare, Kimberly McCleary, Monica Gow
STUDY OBJECTIVES: Describe common symptoms, comorbidities, functional limitations, and treatment responsiveness among patients with narcolepsy. Investigate the effect of pediatric onset of narcolepsy symptoms on time to diagnosis of narcolepsy and presence of comorbid depression. METHODS: Cross-sectional survey of 1,699 people in the United States with self-reported diagnosis of narcolepsy. We utilized mixed-methods data analyses to report study findings. RESULTS: Most participants reported receiving a diagnosis of narcolepsy more than 1 y after symptom onset...
November 28, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27922722/topiramate-versus-carbamazepine-monotherapy-for-epilepsy-an-individual-participant-data-review
#8
REVIEW
Sarah J Nolan, Maria Sudell, Catrin Tudur Smith, Anthony G Marson
BACKGROUND: Epilepsy is a common neurological condition in which abnormal electrical discharges from the brain cause recurrent unprovoked seizures. It is believed that with effective drug treatment, up to 70% of individuals with active epilepsy have the potential to become seizure-free and go into long-term remission shortly after starting drug therapy, the majority of which may be able to achieve remission with a single antiepileptic drug (AED).The correct choice of first-line antiepileptic therapy for individuals with newly diagnosed seizures is of great importance...
December 6, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27919514/the-psychological-impact-of-symptoms-related-to-esophagogastric-cancer-resection-presenting-in-primary-care-a-national-linked-database-study
#9
G Bouras, S R Markar, E M Burns, J R Huddy, A Bottle, T Athanasiou, A Darzi, G B Hanna
BACKGROUND: The objective was to evaluate incidence, risk factors and impact of postoperative symptoms following esophagogastric cancer resection in primary care. METHODS: Patients undergoing esophagogastrectomy for cancer from 1998 to 2010 with linked records in Clinical Practice Research Datalink, Hospital Episodes Statistics and Office of National Statistics databases were studied. The recording of codes for reflux, dysphagia, dyspepsia, nausea, vomiting, dumping, diarrhea, steatorrhea, appetite loss, weight loss, pain and fatigue were identified up to 12 months postoperatively...
November 9, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27919499/quality-of-life-and-its-correlates-in-adolescent-multiple-sclerosis-patients
#10
Slavica Ostojic, Dejan Stevanovic, Jasna Jancic
INTRODUCTION: Measures of health-related quality of life (HRQOL) are considered to be more comprehensive in health outcome assessments than scales assessing only the degree of neurological deficit. OBJECTIVE: The aim of the study was to evaluate HRQOL and its correlates among adolescents with multiple sclerosis (MS) in Serbia. METHODS: Demographic, clinical, and patient-reported outcome data were collected for 21 adolescents with MS, aged 14-18 years...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27919496/cognitive-function-did-not-improve-after-initiation-of-natalizumab-treatment-in-relapsing-remitting-multiple-sclerosis-a-prospective-one-year-dual-control-group-study
#11
M Sundgren, Fredrik Piehl, Åke Wahlin, Tom Brismar
BACKGROUND: Cognitive impairment in multiple sclerosis (MS) is common and has severe implications. Natalizumab (NZ) has documented effects on relapse rate and radiological disease activity in relapsing-remitting MS (RRMS) but studies regarding its specific effects on cognitive functioning are few. Previous studies have reported improvement, however, often lacking relevant control groups. The objective of the present study was to evaluate the cognitive effects of NZ treatment, compared to patients on stable first-line treatment and healthy control subjects...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27918654/cold-water-immersion-and-contrast-water-therapy-do-not-improve-short-term-recovery-following-resistance-training
#12
Christos K Argus, James R Broatch, Aaron C Petersen, Remco Polman, David J Bishop, Shona Halson
PURPOSE: An athlete's ability to recover quickly is important when there is limited time between training and competition. As such, recovery strategies are commonly used to expedite the recovery process. The purpose of this study was to determine the effectiveness of both cold water immersion (CWI) and contrast water therapy (CWT) compared to control on short-term recovery (<4h) following a single full-body resistance training session. METHODS: Thirteen males (age, 26 ± 5 years; weight, 79 ± 7 kg; height, 177 ± 5 cm) were assessed for perceptual (fatigue and soreness) and performance measures (maximal voluntary isometric contraction (MVC) of the knee extensors, weighted and unweighted countermovement jumps) prior to and immediately following the training session...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27918176/comparing-depression-screening-tools-in-persons-with-multiple-sclerosis-ms
#13
Joshua Hanna, Jonathan B Santo, Mervin Blair, Kathy Smolewska, Erin Warriner, Sarah A Morrow
OBJECTIVE: Depression is more common among persons with multiple sclerosis (MS) than the general population. Depression in MS is associated with reduced quality of life, transition to unemployment, and cognitive impairment. Two proposed screening measures for depression in MS populations are the Hospital Anxiety and Depression Scale (HADS) and the Beck Depression Inventory-Fast Screen (BDI-FS). Our objective was to compared the associations of the BDI-FS and the HADS-D scores with history of depressive symptoms, fatigue, and functional outcomes to determine the differential clinical utility of these screening measures among persons with MS...
December 5, 2016: Rehabilitation Psychology
https://www.readbyqxmd.com/read/27917746/insomnia-in-breast-cancer-independent-symptom-or-symptom-cluster
#14
Philip R Gehrman, Sheila N Garland, Lea Ann Matura, Jun Mao
OBJECTIVE: This study examined insomnia in the context of breast cancer, both as an independent symptom and as a component of a symptom cluster that includes depression, anxiety, fatigue, and pain. METHOD: Women with a history of breast cancer currently taking an aromatase inhibitor and who had completed cancer treatment at least one month prior to enrollment were included (n = 413). Participants completed validated measures of insomnia, fatigue, pain, depression, and anxiety...
December 5, 2016: Palliative & Supportive Care
https://www.readbyqxmd.com/read/27914470/symptom-profiles-and-inflammatory-markers-in-moderate-to-severe-copd
#15
Huong Q Nguyen, Jerald R Herting, Kenneth C Pike, Sina A Gharib, Gustavo Matute-Bello, Soo Borson, Ruth Kohen, Sandra G Adams, Vincent S Fan
BACKGROUND: Physical and psychological symptoms are the hallmark of patients' subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. METHODS: We conducted latent class analyses of three physical (dyspnea, fatigue, and pain) and two psychological symptoms (depression and anxiety) in 302 patients with moderate to severe COPD using baseline data from a longitudinal observational study of depression in COPD...
December 3, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27913001/cancer-related-fatigue-persistent-pervasive-and-problematic
#16
REVIEW
Lynn H Gerber
Cancer-related fatigue (CRF) is commonly reported by patients with cancer before, during, and after treatment. It is a persistent sense of tiredness that interferes with function, is distressing, and requires monitoring and, possibly, treatment. Fatigue assessment requires objective measures and self-reports, such as Functional Assessment of Cancer Therapy-Fatigue. Significant contributors to CRF include anemia, pain, insomnia, depressive symptoms, and elevated BMI. Elevated inflammatory cytokines, diabetes mellitus, cortisol, and cellular dysregulation have been associated with CRF...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27911474/is-chelation-therapy-efficient-for-the-treatment-of-intravenous-metallic-mercury-intoxication
#17
Daniela Pelclova, Stepanka Vlckova, Ondrej Bezdicek, Manuela Vaneckova, Pavel Urban, Petr Ridzon, Pavel Diblik, Tomas Navratil, Pavlina Klusackova, Kamil Vlcek, Olga Benesova, Pavel Trestik, Jiri Homolka, Sergey Zakharov
The efficacy of treatment for intravenous elemental mercury intoxication has not been fully studied with regard to clinical outcomes, and treatment recommendations vary. We treated a 41-year-old man with a history of drug abuse and depression who attempted suicide using 1 mL (13.53 g) metallic Hg i.v. He was admitted to the hospital two months later for dyspnoea and thoracic pain and was diagnosed with pneumonia. Hg deposits were seen in the lungs and extra-pulmonary organs. His blood level (372 μg/L) exceeded the population level of 5 μg/L by more than 70-fold...
December 2, 2016: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27911284/different-types-of-exercise-in-multiple-sclerosis-aerobic-exercise-or-pilates-a-single-blind-clinical-study
#18
Bilge Kara, Fadime Küçük, Esra Coşkuner Poyraz, Melda Soysal Tomruk, Egemen İdıman
BACKROUND: The aim of our study is to examine effects of aerobic and Pilates exercises on disability, cognition, physical performance, balance, depression and fatigue in relapsing-remitting Multiple Sclerosis (MS) patients as compared to healthy controls. METHODS: The subjects were divided as aerobic exercise (n = 26), Pilates (n = 9), and the healthy control group (n = 21). We used MSFC, physical performance, Berg balance scale, Beck depression scale, fatique impact scale...
November 25, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27910097/chronic-migraine-an-update-on-physiology-imaging-and-the-mechanism-of-action-of-two-available-pharmacologic-therapies
#19
Sheena K Aurora, Mitchell F Brin
Several lines of research support the hypothesis that migraine is a spectrum of illness, with clinical symptoms that vary along a continuum from episodic migraine to chronic migraine. Physiologic changes may result in episodic migraine evolving into chronic migraine over months to years in susceptible individuals. With chronification, headache frequency increases, becoming more disabling and less responsive to therapy. Neurophysiologic and functional imaging research has reported that chronic migraine may be associated with severity-specific metabolic, functional, and structural abnormalities in the brainstem...
December 2, 2016: Headache
https://www.readbyqxmd.com/read/27908883/association-between-cognitive-complaints-and-vulnerability-to-environmental-distraction-in-multiple-sclerosis
#20
John J Randolph, Jennifer S Randolph, Heather A Wishart
OBJECTIVE: Individuals with multiple sclerosis (MS) often report cognitive dysfunction, although neuropsychological evaluation findings may not correlate with subjective concerns. One factor that may explain this lack of correspondence is the controlled testing environment, which differs from busier settings where cognitive lapses are noted to occur. This study used a novel environmental manipulation to determine whether individuals with MS who report cognitive dysfunction are more vulnerable to the effects of auditory distraction during neuropsychological testing...
December 1, 2016: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
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