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Paulo F Almeida

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https://www.readbyqxmd.com/read/29898095/brazilian-legislation-on-genetic-heritage-harms-biodiversity-convention-goals-and-threatens-basic-biology-research-and-education
#1
EDITORIAL
Ruy José V Alves, Marcelo Weksler, João A Oliveira, Paulo A Buckup, José P Pombal, Hélcio R G Santana, Adriano Lúcio Peracchi, Alexander W A Kellner, Alexandre Aleixo, Alfredo Ricardo L Bonino, Alzira Maria P DE Almeida, Ana Luisa Albernaz, Camila C Ribas, Carla Zilberberg, Carlos Eduardo V Grelle, Carlos Frederico D DA Rocha, Carlos José E Lamas, Célio Fernando B Haddad, Cibele R Bonvicino, Cynthia P A Prado, Daniela O DE Lima, Denise C Rossa-Feres, Fabrício R Dos Santos, Fátima Regina G Salimena, Fernando A Perini, Flávio A Bockmann, Francisco Luís Franco, Gisele M L Del Giudice, Guarino R Colli, Ima Célia G Vieira, Jader Marinho-Filho, Jane M C F Werneck, Jorge A D Dos Santos, Jorge Luiz DO Nascimento, Jorge Luiz Nessimian, José Luis P Cordeiro, Kleber Del Claro, Leandro O Salles, Lilian Casatti, Lucia Helena R Py-Danie, Luís Fábio Silveira, Luís Felipe Toledo, Luiz F DE Oliveira, Luiz Roberto Malabarba, Marcelo D DA Silva, Márcia S Couri, Márcio R C Martins, Marcos D S Tavares, Marcos Eduardo G Sobral, Marcus Vinícius Vieira, Maria DE Lourdes A Oliveira, Mário César C DE Pinna, Michael J G Hopkins, Mirco Solé, Naércio A Menezes, Paulo Passos, Paulo Sergio D'Andrea, Pedro C E A Pinto, Pedro L Viana, Peter M Toledo, Roberto E Dos Reis, Roberto Vilela, Rogério P Bastos, Rosane G Collevatti, Rui C Silva, Santiago C Fisher, Ulisses Caramaschi
No abstract text is available yet for this article.
April 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29741195/polypharmacy-but-not-potential-inappropriate-prescription-was-associated-with-frailty-in-older-adults-from-a-middle-income-country-outpatient-clinic
#2
I Aprahamian, M M Biella, G Vano Aricó de Almeida, F Pegoraro, A V Alves Pedrini, B Cestari, L H Bignotto, B Alvarez Ribeiro de Melo, J E Martinelli
OBJECTIVES: the aims of the present study were: (1) investigate the prevalence and association of polypharmacy and pre-frailty or frailty in a middle-income country sample of older adults; and (2) evaluate the prevalence of potential inappropriate prescription (PIP) and its association with pre-frailty or frailty. DESIGN: Cross-sectional observational study. SETTING: Outpatient center at a university-based hospital in the state of São Paulo, Brazil...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29701353/freedom-solo-versus-trifecta-bioprotheses-clinical-and-hemodynamic-evaluation-after-propensity-score-matching
#3
Rui J Cerqueira, Renata Melo, Soraia Moreira, Francisca A Saraiva, Marta Andrade, Elson Salgueiro, Jorge Almeida, Mário J Amorim, Paulo Pinho, André Lourenço, Adelino F Leite-Moreira
INTRODUCTION: To compare stentless Freedom Solo and stented Trifecta aortic bioprostheses regarding hemodynamic profile, left ventricular mass regression, early and late postoperative outcomes and survival. METHODS: Longitudinal cohort study of consecutive patients undergoing aortic valve replacement (from 2009 to 2016) with either Freedom Solo or Trifecta at one centre. Local databases and national records were queried. Postoperative echocardiography (3-6 months) was obtained for hemodynamic profile (mean transprosthetic gradient and effective orifice area) and left ventricle mass determination...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29607162/early-and-mid-term-haemodynamic-performance-and-clinical-outcomes-of-st-jude-medical-trifecta%C3%A2-valve
#4
Renata Raimundo, Soraia Moreira, Francisca Saraiva, Rui J Cerqueira, Pedro Teixeira, Elson Salgueiro, André Lourenço, Mário J Amorim, Jorge Almeida, Paulo Pinho, Adelino F Leite-Moreira
Background: New models of aortic bioprostheses have proven excellent early haemodynamic profile, but their mid and long-term performance warrants further systematic assessment. The aim of this study is to report clinical and haemodynamic performance of St. Jude Medical Trifecta bioprosthesis during 5 years of implantation. Methods: We performed a single centre, retrospective, observational and descriptive study including all 556 individuals who underwent aortic valve replacement (AVR) with the Trifecta bioprosthesis (between July of 2011 and June of 2016)...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29522211/innovative-methodology-for-point-of-care-circulating-cathodic-antigen-with-rapid-urine-concentration-for-use-in-the-field-for-detecting-low-schistosoma-mansoni-infection-and-for-control-of-cure-with-high-accuracy
#5
Rafaella F Q Grenfell, Diana Taboada, Lucélia A Coutinho, Maria Luysa C Pedrosa, Jéssica V Assis, Matheus S P Oliveira, Renata R Cruz, Aureo Almeida, Vanessa Silva-Moraes, Naftale Katz, Paulo Marcos Z Coelho
Background: Prior to eliminating schistosomiasis, efforts must address accurate and fast individual diagnosis. Diagnosis is still inaccurate by parasitological and point-of-care circulating cathodic antigen (POC-CCA) in areas of low endemicity. Methods: Our group has optimized POC-CCA with a 30 min urine concentration step with no need for specialized technicians or equipment and with high accuracy. We evaluated this new method, called POC-CCA filter (FLT), in two Brazilian endemic areas with distinct profiles...
January 1, 2018: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29493182/the-pubovesical-complex-sparing-technique-on-laparoscopic-radical-prostatectomy
#6
Rafael Batista Rebouças, Rodrigo Campos Monteiro, João Paulo Pereira Lima, Filipe Pádua B F Almeida, Cesar Araujo Britto, Marcos Tobias-Machado, Carlo Passerotti
INTRODUCTION: Preservation of urinary continence is a great challenge in Radical Prostatectomy. In order to improve functional results, Asimakopoulos et al. (2010) described a robot-assisted surgical technique with preservation of the pubovesical complex (PVC). We present a pure laparoscopic execution. PRESENTATION: A 61-year-old male patient with a diagnosis of prostate cancer, with PSA 6.54ng/ml, DRE: T1C and Gleason 6 (3+3) 1/12 fragments. All therapeutic possibilities were discussed, including active surveillance...
March 1, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29451659/environmental-factors-can-influence-dengue-reported-cases
#7
Marco Antonio F Carneiro, Beatriz da C A Alves, Flávia de Sousa Gehrke, José Nuno Domingues, Nelson Sá, Susana Paixão, João Figueiredo, Ana Ferreira, Cleonice Almeida, Amaury Machi, Eriane Savóia, Vânia Nascimento, Fernando Fonseca
INTRODUCTION: Global climate changes directly affect the natural environment and contribute to an increase in the transmission of diseases by vectors. Among these diseases, dengue is at the top of the list. The aim of our study was to understand the consequences of temporal variability of air temperature in the occurrence of dengue in an area comprising seven municipalities of the Greater São Paulo. METHOD: Characterization of a temporal trend of the disease in the region between 2010 and 2013 was performed through analysis of the notified number of dengue cases over this period...
November 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29322308/quality-of-life-of-patients-with-type-1-diabetes-mellitus-using-insulin-analog-glargine-compared-with-nph-insulin-a-systematic-review-and-policy-implications
#8
REVIEW
Paulo H R F Almeida, Thales B C Silva, Francisco de Assis Acurcio, Augusto A Guerra Júnior, Vania E Araújo, Leonardo M Diniz, Brian Godman, Alessandra M Almeida, Juliana Alvares
INTRODUCTION: Insulin analog glargine (GLA) has been available as one of the therapeutic options for patients with type 1 diabetes mellitus to enhance glycemic control. Studies have shown that a decrease in the frequency of hypoglycemic episodes improves the quality of life (QoL) of diabetic patients. However, there are appreciable acquisition cost differences between different insulins. Consequently, there is a need to assess their impact on QoL to provide future guidance to health authorities...
January 10, 2018: Patient
https://www.readbyqxmd.com/read/29297430/tuberculosis-among-south-american-immigrants-in-s%C3%A3-o-paulo-municipality-an-analysis-in-space-and-time
#9
P F P S Pinto, F C Neto, M C S de Almeida Ribeiro
OBJECTIVE: To identify spatial and temporal, and spatial variation in temporal trends in clusters of tuberculosis (TB) among South American migrants residing in São Paulo municipality, SP, Brazil, between 2006 and 2013. DESIGN: An ecological descriptive study was conducted using data obtained from official TB reports and the 2010 Brazilian demographic census. Clusters were identified using scan statistics and SaTScan software; those with P < 0.05 were considered statistically significant...
January 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29287444/polycyclic-aromatic-hydrocarbons-content-and-fatty-acids-profile-in-coconut-safflower-evening-primrose-and-linseed-oils
#10
Simone Alves da Silva, Elizabeth A F da Silva Torres, Adriana Palma de Almeida, Geni Rodrigues Sampaio
This study aimed at evaluating the polycyclic aromatic hydrocarbons (PAHs) contamination of commercial vegetable oils and examined the identity through the fatty acids profiles. Coconut, safflower, evening primrose, and linseed oils marketed in São Paulo (Brazil) were investigated totaling 69 samples. Four PAHs, benzo[a]anthracene (BaA), chrysene (Chr), benzo[b]fluoranthene (BbF), and benzo[a]pyrene (BaP), were detected in 96% of the samples at individual levels ranging from not detected to 14.99 μg kg-1 ...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29187682/bacterial-glycerol-oxidation-coupled-to-sulfate-reduction-at-neutral-and-acidic-ph
#11
Sidnei C Santos, Martin G Liebensteiner, Antonie H van Gelder, Mauricio R Dimitrov, Paulo F Almeida, Cristina M Quintella, Alfons J M Stams, Irene Sánchez-Andrea
Glycerol is a main co-product of biodiesel production. Crude glycerol may serve as a cheap and attractive substrate in biotechnological applications, e.g. for the production of valuable chemicals or as an electron donor for reduction processes. In this work, sulfate reduction with glycerol was studied at neutral and acidic pH using bioreactor sludge samples and Tinto River sediments as a source of inoculum, respectively. Communities of sulfate-reducing bacteria (SRB) and fermentative bacteria were co-enriched at both pH values...
March 27, 2018: Journal of General and Applied Microbiology
https://www.readbyqxmd.com/read/29170530/identification-and-analysis-of-seven-effector-protein-families-with-different-adaptive-and-evolutionary-histories-in-plant-associated-members-of-the-xanthomonadaceae
#12
Renata de A B Assis, Lorraine Cristina Polloni, José S L Patané, Shalabh Thakur, Érica B Felestrino, Julio Diaz-Caballero, Luciano Antonio Digiampietri, Luiz Ricardo Goulart, Nalvo F Almeida, Rafael Nascimento, Abhaya M Dandekar, Paulo A Zaini, João C Setubal, David S Guttman, Leandro Marcio Moreira
The Xanthomonadaceae family consists of species of non-pathogenic and pathogenic γ-proteobacteria that infect different hosts, including humans and plants. In this study, we performed a comparative analysis using 69 fully sequenced genomes belonging to this family, with a focus on identifying proteins enriched in phytopathogens that could explain the lifestyle and the ability to infect plants. Using a computational approach, we identified seven phytopathogen-enriched protein families putatively secreted by type II secretory system: PheA (CM-sec), LipA/LesA, VirK, and four families involved in N-glycan degradation, NixE, NixF, NixL, and FucA1...
November 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29130685/daptomycin-phosphatidylglycerol-domains-in-lipid-membranes
#13
Mark A Kreutzberger, Antje Pokorny, Paulo F Almeida
Daptomycin is an acidic, 13-amino acid, cyclic polypeptide that contains a number of nonproteinogenic residues and is modified at its N-terminus with a decanoyl chain. It has been in clinical use since 2003 against selected drug-resistant Staphylococcus aureus and Enterococcus spp infections. In vitro, daptomycin is active against Gram-positive pathogens at low concentrations but its antibiotic activity depends critically on the presence of calcium ions. This dependence has been thought to arise from binding of one or two Ca2+ ions to daptomycin as a required step in its interaction with the bacterial membrane...
November 28, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29053913/morphological-changes-of-the-internal-carotid-artery-prevalence-and-characteristics-a-clinical-and-ultrasonographic-study-in-a-series-of-19-804-patients-over-25-years-old
#14
H F G Martins, A Mayer, P Batista, F Soares, V Almeida, A J Pedro, V Oliveira
BACKGROUND AND PURPOSE: Morphological changes of the internal carotid arteries (McICA) are frequently found during cervical ultrasound studies. However, the etiology of McICA remains controversial. During this study, the prevalence and demographic characteristics of McICA, such as kinking, coiling or looping identified by Doppler ultrasound, were analysed and its relationship with vascular risk factors and stroke was assessed. METHODS: A retrospective study was performed by analysing 19 804 patients who were subjected to cervical ultrasonographic study between January 2000 and June 2012...
January 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28867316/endoscopic-endonasal-surgery-for-treatment-of-pituitary-apoplexy-16-years-of-experience-in-a-specialized-pituitary-center
#15
Jackson A Gondim, Lucas Alverne F de Albuquerque, Joao Paulo Almeida, Tania Bulcao, Erika Gomes, Michele Schops, Raquel Vasconcelos, Flora da Paz, Sergio Botelho Guimarães
OBJECTIVE: Symptomatic pituitary apoplexy is a rare but life-threatening condition caused by sudden hemorrhage or infarction of a pituitary adenoma. In the current study, we aim to evaluate the clinical presentation, management, and clinical outcomes in a cohort of patients who were treated for this condition in our center in the last 16 years. METHODS: We performed a retrospective analysis of all patients who underwent endoscopic endonasal surgery for treatment of symptomatic pituitary apoplexy between 2001 and 2016 in our center...
December 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28838147/specific-biomarkers-associated-with-neurological-complications-and-congenital-central-nervous-system-abnormalities-from-zika-virus-infected-patients-in-brazil
#16
Yiu-Wing Kam, Juliana Almeida Leite, Fok-Moon Lum, Jeslin J L Tan, Bernett Lee, Carla C Judice, Daniel Augusto de Toledo Teixeira, Robert Andreata-Santos, Marco A Vinolo, Rodrigo Angerami, Mariangela Ribeiro Resende, Andre Ricardo Ribas Freitas, Eliana Amaral, Renato Passini Junior, Maria Laura Costa, José Paulo Guida, Clarice Weis Arns, Luis Carlos S Ferreira, Laurent Rénia, Jose Luiz Proença-Modena, Lisa F P Ng, Fabio T M Costa
Background: Zika virus (ZIKV) infections have been linked to different levels of clinical outcomes, ranging from mild rash and fever to severe neurological complications and congenital malformations. Methods: We investigated the clinical and immunological response, focusing on the immune mediators profile in 95 acute ZIKV-infected adult patients from Campinas, Brazil. These patients included 6 pregnant women who later delivered during the course of this study. Clinical observations were recorded during hospitalization...
July 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28834711/and-yet-it-moves
#17
Paulo F Almeida
No abstract text is available yet for this article.
August 22, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28741872/breast-disease-in-men-in-metropolitan-s%C3%A3-o-paulo-brazil
#18
Renata Thaís de Almeida Barbosa, Maria Auxiliadora F Vertamatti, Claudia Arab, Tânia Brusque Crocetta, Ricardo Lencioni Mazzei, Ivo Carelli Filho, Ricardo Faure, Izabella Brandão Mendes, Luiz Carlos de Abreu
Although rare, breast cancer in males represents 1% of all cancer in men, and has shown increasing incidence in 25 years. To analyze age, gender, type of procedure performed and diagnosis of all cases of breast diseases in a public hospital in Sao Paulo, Brazil, with special focus on men. Cross-sectional study of breast surgery in 2010-2014 at Hospital Municipal Universitario de Sao Bernardo do Campo, Brazil. In the period 999 breast surgery were carried out. Patients with benign diseases were about 30 years old and patients with malignant diseases were over 50...
March 2018: Breast Journal
https://www.readbyqxmd.com/read/28732311/solid-and-aqueous-magnetoliposomes-as-nanocarriers-for-a-new-potential-drug-active-against-breast-cancer
#19
Ana Rita O Rodrigues, Pedro M F Mendes, Pedro M L Silva, V A Machado, Bernardo G Almeida, J P Araújo, Maria-João R P Queiroz, Elisabete M S Castanheira, Paulo J G Coutinho
Iron oxide nanoparticles, with diameters around 12nm, were synthesized by coprecipitation method. The magnetic properties indicate a superparamagnetic behavior with a coercive field of 9.7Oe and a blocking temperature of 118K. Both aqueous and solid magnetoliposomes containing magnetite nanoparticles have sizes below 150nm, suitable for biomedical applications. Interaction between both types of magnetoliposomes and models of biological membranes was proven. A new antitumor compound, a diarylurea derivative of thienopyridine, active against breast cancer, was incorporated in both aqueous and solid magnetoliposomes, being mainly located in the lipid membrane...
October 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28693539/genomic-prediction-in-contrast-to-a-genome-wide-association-study-in-explaining-heritable-variation-of-complex-growth-traits-in-breeding-populations-of-eucalyptus
#20
Bárbara S F Müller, Leandro G Neves, Janeo E de Almeida Filho, Márcio F R Resende, Patricio R Muñoz, Paulo E T Dos Santos, Estefano Paludzyszyn Filho, Matias Kirst, Dario Grattapaglia
BACKGROUND: The advent of high-throughput genotyping technologies coupled to genomic prediction methods established a new paradigm to integrate genomics and breeding. We carried out whole-genome prediction and contrasted it to a genome-wide association study (GWAS) for growth traits in breeding populations of Eucalyptus benthamii (n =505) and Eucalyptus pellita (n =732). Both species are of increasing commercial interest for the development of germplasm adapted to environmental stresses...
July 11, 2017: BMC Genomics
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