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Paulo Almeida

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https://www.readbyqxmd.com/read/27903122/management-and-outcome-of-recurrent-adult-craniopharyngiomas-an-analysis-of-42-cases-with-long-term-follow-up
#1
Mazda K Turel, Georgios Tsermoulas, Lior Gonen, George Klironomos, Joao Paulo Almeida, Gelareh Zadeh, Fred Gentili
OBJECTIVE The treatment of recurrent and residual craniopharyngiomas is challenging. In this study the authors describe their experience with these tumors and make recommendations on their management. METHODS The authors performed an observational study of adult patients (≥ 18 years) with recurrent or residual craniopharyngiomas that were managed at their tertiary center. Retrospective data were collected on demographics and clinical, imaging, and treatment characteristics from patients who had a minimum 2-year follow-up...
December 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27901193/physicochemical-photophysical-characterization-and-angiogenic-properties-of-curcuma-longa-essential-oil
#2
Lilhian A Araújo, Rafael G M Araújo, Flávia O Gomes, Susy R Lemes, Luciane M Almeida, Lauro J Q Maia, Pablo J Gonçalves, Fátima Mrué, Nelson J Silva-Junior, Paulo R DE Melo-Reis
This study analyzed the physicochemical and photophysical properties of essential oil of Curcuma longa and its angiogenic potential. The results showed that curcumin is the main fluorescent component present in the oil, although the amount is relatively small. The experimental chorioallantoic membrane model was used to evaluate angiogenic activity, showing a significant increase in the vascular network of Curcuma longa and positive control groups when compared to the neutral and inhibitor controls (P <0...
2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27896890/diterpenes-as-lead-molecules-against-neglected-tropical-diseases
#3
REVIEW
Marcus Vinícius Oliveira Barros de Alencar, João Marcelo de Castro E Sousa, Hercília Maria Lins Rolim, Maria das Graças Freire de Medeiros, Gilberto Santos Cerqueira, Fernanda Regina de Castro Almeida, Antônia Maria das Graças Lopes Citó, Paulo Michel Pinheiro Ferreira, José Arimatéia Dantas Lopes, Ana Amélia de Carvalho Melo-Cavalcante, Md Torequl Islam
Nowadays, neglected tropical diseases (NTDs) are reported to be present everywhere. Poor and developing areas in the world have received great attention to NTDs. Drug resistance, safety profile, and various challenges stimulate the search for alternative medications. Plant-based drugs are viewed with great interest, as they are believed to be devoid of side effects. Diterpenes, a family of essential oils, have showed attractive biological effects. A systematic review of the literature was carried out to summarize available evidences of diterpenes against NTDs...
November 29, 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27890589/aged-mice-receiving-caffeine-since-adulthood-show-distinct-patterns-of-anxiety-related-behavior
#4
Paulo Henrique S Botton, Daniela Pochmann, Andreia S Rocha, Fernanda Nunes, Amanda S Almeida, Daniela M Marques, Lisiane O Porciúncula
Caffeine is the psychostimulant most consumed worldwide. Anxiogenic effects of caffeine have been described in adult animalswith controversial findings about its anxiogenic potential. Besides, the effects of caffeine on anxiety with aging are still poorly known. In this study, adult mice (6months old) started to receive caffeine (0.3 and 1.0mg/mL, drinking water) during 12-14months only in the light cycle and at weekdays. The open field (OF) and elevated plus maze (EPM) testing were used to determine the effects of caffeine on anxiety-related behavior in adult and aged mice (18-20months old)...
November 24, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/27888673/clinical-correlates-of-pp65-antigenemia-monitoring-in-the-first-months-of-post-kidney-transplant-in-patients-undergoing-universal-prophylaxis-or-preemptive-therapy
#5
Fabiana Rabe Carvalho, Rachel Ingrid Juliboni Cosendey, Cintia Fernandes Souza, Thalia Medeiros, Paulo Alexandre Menezes, Andrea Alice Silva, Jorge Reis Almeida, Jocemir Ronaldo Lugon
INTRODUCTION: Human cytomegalovirus (HCMV) is a major cause of morbidity in kidney transplant patients. OBJECTIVES: We aimed to study viral replication and serological response in the first months post kidney transplant in patients undergoing universal prophylaxis or preemptive therapy and correlate the findings with the clinical course of HCMV infection. PATIENTS AND METHODS: Independent from the clinical strategy adopted for managing HCMV infection, prophylaxis versus preemptive therapy, the pp65 antigenemia assay and serological response were assessed on the day of transplantation, and then weekly during the first three months of post-transplant...
November 23, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27884174/comparative-morphological-and-molecular-analysis-confirms-the-presence-of-the-west-nile-virus-mosquito-vector-culex-univittatus-in-the-iberian-peninsula
#6
Verónica Mixão, Daniel Bravo Barriga, Ricardo Parreira, Maria Teresa Novo, Carla Alexandra Sousa, Eva Frontera, Marietjie Venter, Leo Braack, António Paulo Gouveia Almeida
BACKGROUND: Culex univittatus and Culex perexiguus mosquitoes (Diptera: Culicidae) are competent arbovirus vectors, but with unclear morphological differentiation. In Europe, and in the Iberian Peninsula in particular, the presence of either or both species is controversial. However, in order to conduct adequate surveillance for arboviruses in this region, it is crucial to clarify whether Cx. univittatus is present or not, as well as to critically assess existing differentiation tools...
November 25, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27883957/effect-of-freezing-prior-to-aging-on-myoglobin-redox-forms-and-cie-color-of-beef-from-nellore-and-aberdeen-angus-cattle
#7
Carolina Naves Aroeira, Robledo de Almeida Torres Filho, Paulo Rogério Fontes, Alcinéia de Lemos Souza Ramos, Lúcio Alberto de Miranda Gomide, Márcio Machado Ladeira, Eduardo Mendes Ramos
The objective of this study was to evaluate the effect of freezing prior to wet aging on the color of Nellore and Aberdeen Angus cattle meat. Samples of the Longissimus thoracis muscle were subjected to two treatments: conventional aging (0, 7, 14 and 21days); and freezing (-20°C for 40days) followed by thawing and aging. Freezing promoted (P<0.05) formation of metmyoglobin during aging, especially in Nellore beef. Frozen meats showed (P<0.05) lower lightness (L*) values and higher redness (a*), chroma (C*) and hue angle (h*) values at the first day of storage, deteriorating quickly with aging time...
November 16, 2016: Meat Science
https://www.readbyqxmd.com/read/27881360/an-observational-registry-of-carotid-endarterectomy-and-carotid-artery-stenting-in-brazil-study-protocol
#8
Edwaldo Edner Joviliano, Winston Bonetti Yoshida, Marcone Lima Sobreira, Regina Moura, Ana Terezinha Guillaumon, Selma Regina De Oliveira Raymundo, Daniel Gustavo Miquelin, Ludvig Hafner, Marcelo Jose Almeida
BACKGROUND: Carotid artery stenting (CAS) and carotid endarterectomy (CEA) are alternative strategies for stroke prevention in patients with atherosclerotic carotid disease. CEA has been considered the first-line treatment for carotid stenosis worldwide, and the safety and efficacy of CAS compared to CEA remains in question. OBJECTIVE: The purpose of this study is to compare the practice and outcomes of CAS and CEA in a real-world setting within public university hospitals in Brazil...
November 23, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27881059/natural-products-with-antiplatelet-action
#9
Gabriela Elisa Hirsch, Paulo Ricardo Nazário Viecili, Amanda Spring de Almeida, Sabrina Nascimento, Fernando Garcez Porto, Juliana Otero, Aline Schmidt, Brenda da Silva, Mariana Migliorini Parisi, Jonatas Zeni Klafke
BACKGROUND: Complex hemostatic mechanisms are involved in the pathophysiology of various diseases, including cardiovascular diseases. Among them, dysregulation of platelet activity is linked to the progression of atherosclerosis and mainly involves platelet aggregation and a decrease in blood flow in the vascular endothelium. The major platelet activation pathways mediated by agonists involve the arachidonic acid pathway, adenosine diphosphate pathway, serotonin pathway, nitric oxide pathway, and action of free radicals on molecules involved in platelet aggregation...
November 23, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27870769/brown-tumors-in-secondary-hyperparathyroidism-in-a-patient-with-lupus-nephritis
#10
Sílvia Fernandes, Paulo Almeida, José Melo-Gomes, José Carlos Romeu
No abstract text is available yet for this article.
December 2016: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/27865673/a-rare-cause-of-acute-coronary-syndrome-kounis-syndrome
#11
João Almeida, Sara Ferreira, Joana Malheiro, Paulo Fonseca, Daniel Caeiro, Adelaide Dias, José Ribeiro, Vasco Gama
Kounis syndrome is an acute coronary syndrome in the context of a hypersensitivity reaction. The main pathophysiological mechanism appears to be coronary vasospasm. We report the case of a patient with a history of allergy to quinolones, who was given ciprofloxacin before an elective surgical procedure and during drug administration developed symptoms and electrocardiographic changes suggestive of ST-segment elevation acute coronary syndrome. The drug was suspended and coronary angiography excluded epicardial coronary disease...
December 2016: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/27865218/-percutaneous-endovascular-aortic-repair-with-local-anesthesia-one-day-surgery
#12
Joel Sousa, Daniel Brandão, Paulo Barreto, Joana Ferreira, José Almeida Lopes, Armando Mansilha
INTRODUCTION: To evaluate the results of the abdominal aortic aneurism endovascular treatment (EVAR), percutaneously and with local anesthesia, according to the concept of one day surgery. MATERIAL AND METHODS: Unicentric, retrospective analysis of patients with aorto-iliac aneurysmal disease, consecutively treated by EVAR with percutaneous access trough the Preclose technique (pEVAR), according to the outpatient criteria, with one overnight stay in the hospital...
June 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27865216/establishing-the-role-of-unlinked-total-elbow-arthroplasty-in-low-demand-patients-a-long-term-follow-up-study
#13
Sara Machado, Isabel Almeida Pinto, Rui Pinto, Paulo Ribeiro de Oliveira
INTRODUCTION: Experience with total elbow arthroplasty is scarce in most centers. It seems to have a significant rate of associated complications. Most studies are based on non-validated outcome measures and short-term results. MATERIAL AND METHODS: We selected patients undergoing unlinked total elbow arthroplasty, with a resultant sample of thirteen cases, with a mean postoperative follow-up of 72 months. We applied the Mayo Elbow Score and all patients underwent an X-ray study, prior to surgery and during the follow-up period...
June 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/27864069/microencapsulated-sln-an-innovative-strategy-for-pulmonary-protein-delivery
#14
Diana P Gaspar, Carmen Serra, Paulo R Lino, Lídia Gonçalves, Pablo Taboada, Carmen Remuñán-López, António J Almeida
Associating protein with nanoparticles is an interesting strategy to improve their bioavailability and biological activity. Solid lipid nanoparticles (SLN) have been sought as carriers for therapeutic proteins transport to the lung epithelium. Nevertheless, because of their low inertia, nanoparticles intended for pulmonary application usually escape from lung deposition. To overcome this problem, the production of spray-dried powders containing nanoparticles has been recently reported. Herein we developed new hybrid microencapsulated SLN for pulmonary administration, containing a model protein (papain, PAP)...
November 15, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27852270/inequalities-in-healthy-life-expectancy-by-brazilian-geographic-regions-findings-from-the-national-health-survey-2013
#15
Célia Landmann Szwarcwald, Paulo Roberto Borges de Souza Júnior, Aline Pinto Marques, Wanessa da Silva de Almeida, Dalia Elena Romero Montilla
BACKGROUND: The demographic shift and epidemiologic transition in Brazil have drawn attention to ways of measuring population health that complement studies of mortality. In this paper, we investigate regional differences in healthy life expectancy based on information from the National Health Survey (PNS), 2013. METHODS: In the survey, a three-stage cluster sampling (census tracts, households and individuals) with stratification of the primary sampling units and random selection in all stages was used to select 60,202 Brazilian adults (18 years and over)...
November 17, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27849298/long-term-mortality-predictors-in-patients-with-small-aortic-annulus-undergoing-aortic-valve-replacement-with-a-19-or-21-mm-bioprosthesis
#16
Jenny Lourdes Rivas de Oliveira, Renato Tambellini Arnoni, Magaly Arrais Dos Santos, Antonio Flávio Sanchez Almeida, Mário Issa, Antoninho Sanfins Arnoni, Paulo Chaccur, Luiz Carlos Bento de Souza
Introduction: Replacement of the aortic valve in patients with a small aortic annulus is associated with increased morbidity and mortality. A prosthesis-patient mismatch is one of the main problems associated with failed valves in this patient population. Objective: To evaluate the long-term mortality predictors in patients with a small aortic annulus undergoing aortic valve replacement with a bioprosthesis. Methods: In this retrospective observational study, a total of 101 patients undergoing aortic valve replacement from January 2000 to December 2010 were studied...
July 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27847652/orthodontic-protocol-using-mini-implant-for-class-ii-treatment-in-patient-with-special-needs
#17
Fernando Pedrin Carvalho Ferreira, Anderson Paulo Barbosa Lima, Eliana de Cássia Molina de Paula, Ana Claudia de Castro Ferreira Conti, Danilo Pinelli Valarelli, Renata Rodrigues de Almeida-Pedrin
Improving facial and dental appearance and social interaction are the main factors for special needs (SN) patients to seek orthodontic treatment. The cooperation of SN patients and their parents is crucial for treatment success. Objective. To show through a case report the satisfactory results, both functional and esthetic, in patients with intellectual disability, congenital nystagmus, and severe scoliosis. Materials Used. Pendulum device with mini-implants as anchorage unit. Results. Improvement of facial and dental esthetics, correction of Class II malocclusion, and no root resorption shown in the radiographic follow-up...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27843167/use-of-transgenic-aedes-aegypti-in-brazil-risk-perception-and-assessment
#18
Paulo Paes de Andrade, Francisco José Lima Aragão, Walter Colli, Odir Antônio Dellagostin, Flávio Finardi-Filho, Mario Hiroyuki Hirata, Amaro de Castro Lira-Neto, Marcia Almeida de Melo, Alexandre Lima Nepomuceno, Francisco Gorgônio da Nóbrega, Gutemberg Delfino de Sousa, Fernando Hercos Valicente, Maria Helena Bodanese Zanettini
The OX513A strain of Aedes aegypti, which was developed by the British company Oxitec, expresses a self-limiting transgene that prevents larvae from developing to adulthood. In April 2014, the Brazilian National Technical Commission on Biosafety completed a risk assessment of OX513A and concluded that the strain did not present new biological risks to humans or the environment and could be released in Brazil. At that point, Brazil became the first country to approve the unconstrained release of a genetically modified mosquito...
October 1, 2016: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/27836030/validation-of-a-new-technique-to-detect-cryptosporidium-spp-oocysts-in-bovine-feces
#19
Sandra Valéria Inácio, Jancarlo Ferreira Gomes, Bruno César Miranda Oliveira, Alexandre Xavier Falcão, Celso Tetsuo Nagase Suzuki, Bianca Martins Dos Santos, Monally Conceição Costa de Aquino, Rafaela Silva de Paula Ribeiro, Danilla Mendes de Assunção, Pamella Almeida Freire Casemiro, Marcelo Vasconcelos Meireles, Katia Denise Saraiva Bresciani
Due to its important zoonotic potential, cryptosporidiosis arouses strong interest in the scientific community, because, it was initially considered a rare and opportunistic disease. The parasitological diagnosis of the causative agent of this disease, the protozoan Cryptosporidium spp., requires the use of specific techniques of concentration and permanent staining, which are laborious and costly, and are difficult to use in routine laboratory tests. In view of the above, we conducted the feasibility, development, evaluation and intralaboratory validation of a new parasitological technique for analysis in optical microscopy of Cryptosporidium spp...
November 1, 2016: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/27832961/emergence-of-colistin-resistance-in-the-largest-university-hospital-complex-of-s%C3%A3-o-paulo-brazil-over-five-years
#20
Flávia Rossi, Raquel Girardello, Ana Paula Cury, Thais Sabato Romano Di Gioia, João Nóbrega de Almeida, Alberto José da Silva Duarte
Colistin resistance involving Gram-negative bacilli infections is a challenge for health institutions around of the world. Carbapenem-resistance among these isolates makes colistin the last therapeutic option for this treatment. Colistin resistance among Enterobacteriaceae, Acinetobacter spp., and Pseudomonas spp. was evaluated between 2010 and 2014 years, at Hospital das Clínicas, São Paulo, Brazil. Over five years 1346 (4.0%) colistin resistant Gram-negative bacilli were evaluated. Enterobacteriaceae was the most frequent (86...
November 7, 2016: Brazilian Journal of Infectious Diseases
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