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Paulo Almeida

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https://www.readbyqxmd.com/read/28808799/transorbital-endoscopic-approach-for-exposure-of-the-sylvian-fissure-middle-cerebral-artery-and-crural-cistern-an-anatomical-study
#1
João Paulo Almeida, Armando S Ruiz-Treviño, Sathwik R Shetty, Sacit B Omay, Vijay K Anand, Theodore H Schwartz
BACKGROUND: The availability of minimal access instrumentation and endoscopic visualization has revolutionized the field of minimally invasive skull base surgery. The transorbital endoscopic approach using an eyelid incision has been proposed as a new minimally invasive technique for the treatment of skull base pathology, mostly extradural tumors. Our study aims to evaluate the anatomical aspects and potential role of the transorbital endoscopic approach for exposure of the sylvian fissure, middle cerebral artery and crural cistern...
August 14, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28801420/protocol-study-for-a-randomised-controlled-double-blind-clinical-trial-involving-virtual-reality-and-anodal-transcranial-direct-current-stimulation-for-the-improvement-of-upper-limb-motor-function-in-children-with-down-syndrome
#2
Jamile Benite Palma Lopes, Luanda André Collange Grecco, Renata Calhes Franco de Moura, Roberta Delasta Lazzari, Natalia de Almeida Carvalho Duarte, Isabela Miziara, Gileno Edu Lameira de Melo, Arislander Jonathan Lopes Dumont, Manuela Galli, Claudia Santos Oliveira
INTRODUCTION: Down syndrome results in neuromotor impairment that affects selective motor control, compromising the acquisition of motor skills and functional independence. The aim of the proposed study is to evaluate and compare the effects of multiple-monopolar anodal transcranial direct current stimulation and sham stimulation over the primary motor cortex during upper limb motor training involving virtual reality on motor control, muscle activity, cerebral activity and functional independence...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28795275/effects-of-photobiomodulation-therapy-and-topical-non-steroidal-anti-inflammatory-drug-on-skeletal-muscle-injury-induced-by-contusion-in-rats-part-2-biochemical-aspects
#3
Shaiane Silva Tomazoni, Lúcio Frigo, Tereza Cristina Dos Reis Ferreira, Heliodora Leão Casalechi, Simone Teixeira, Patrícia de Almeida, Marcelo Nicolas Muscara, Rodrigo Labat Marcos, Andrey Jorge Serra, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
Muscle injuries trigger an inflammatory process, releasing important biochemical markers for tissue regeneration. The use of non-steroidal anti-inflammatory drugs (NSAIDs) is the treatment of choice to promote pain relief due to muscle injury. NSAIDs exhibit several adverse effects and their efficacy is questionable. Photobiomodulation therapy (PBMT) has been demonstrated to effectively modulate inflammation induced from musculoskeletal disorders and may be used as an alternative to NSAIDs. Here, we assessed and compared the effects of different doses of PBMT and topical NSAIDs on biochemical parameters during an acute inflammatory process triggered by a controlled model of contusion-induced musculoskeletal injury in rats...
August 9, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28794439/maternal-low-intensity-physical-exercise-prevents-obesity-in-offspring-rats-exposed-to-early-overnutrition
#4
Tatiane Aparecida Ribeiro, Laize Peron Tófolo, Isabela Peixoto Martins, Audrei Pavanello, Júlio Cezar de Oliveira, Kelly Valério Prates, Rosiane Aparecida Miranda, Claudinéia Conationi da Silva Franco, Rodrigo Mello Gomes, Flávio Andrade Francisco, Vander Silva Alves, Douglas Lopes de Almeida, Veridiana Mota Moreira, Kesia Palma-Rigo, Elaine Vieira, Gabriel Sergio Fabricio, Marcos Ricardo da Silva Rodrigues, Wilson Rinaldi, Ananda Malta, Paulo Cezar de Freitas Mathias
Low intensity exercise during pregnancy and lactation may create a protective effect against the development of obesity in offspring exposed to overnutrition in early life. To test these hypotheses, pregnant rats were randomly assigned into 2 groups: Sedentary and Exercised, low intensity, on a rodent treadmill at 30% VO2Max /30-minute/session/3x/week throughout pregnancy and the lactation. Male offspring were raised in small litters (SL, 3 pups/dam) and normal litters (NL, 9 pups/dam) as models of early overnutrition and normal feed, respectively...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28793098/effects-of-supportive-telephone-counseling-in-the-metabolic-control-of-elderly-people-with-diabetes-mellitus
#5
Tânia Alves Canata Becker, Carla Regina de Souza Teixeira, Maria Lúcia Zanetti, Ana Emília Pace, Fábio Araújo Almeida, Maria Teresa da Costa Gonçalves Torquato
Objective: the purpose of this study was to evaluate the efficacy of telephone-based support for the metabolic control of elderly patients with diabetes mellitus. Method: a pragmatic study was conducted in two groups, called G1 (n=36) and G2 (n=27), at a health unit from the countryside of São Paulo state. Patients in G1 group received telephone support over four months, through 16 telephone contacts with educational material; for the G2 group the educational material was mailed...
July 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28778042/sub-lethal-effects-of-essential-oil-of-lippia-sidoides-on-drywood-termite-cryptotermes-brevis-blattodea-termitoidea
#6
Abraão Almeida Santos, Bruna Maria Santos de Oliveira, Carlisson Ramos Melo, Ana Paula Santana Lima, Emile Dayara Rabelo Santana, Arie Fitzgerald Blank, Marcelo Coutinho Picanço, Ana Paula Albano Araújo, Paulo Fellipe Cristaldo, Leandro Bacci
The drywood termite Cryptotermes brevis (Walker, 1853) (Kalotermitidae) is one of the most important wood structural pest in the world. Substances from the secondary metabolism of plants (e.g., essential oils) have been considered an environmentally safer form of control for urban pests, such as termites. In the present study, we analyzed the lethal and sub-lethal effects of essential oil of Lippia sidoides and its major components on C. brevis pseudergates in two routes of exposure (contact and fumigation)...
August 1, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28774638/mangrove-endophyte-promotes-reforestation-tree-acacia-polyphylla-growth
#7
Renata Assis Castro, Manuella Nóbrega Dourado, Jaqueline Raquel de Almeida, Paulo Teixeira Lacava, André Nave, Itamar Soares de Melo, João Lucio de Azevedo, Maria Carolina Quecine
Mangroves are ecosystems located in the transition zone between land and sea that serve as a potential source of biotechnological resources. Brazil's extensive coast contains one of the largest mangrove forests in the world (encompassing an area of 25,000km(2) along all the coast). Endophytic bacteria were isolated from the following three plant species: Rhizophora mangle, Laguncularia racemosa and Avicennia nitida. A large number of these isolates, 115 in total, were evaluated for their ability to fix nitrogen and solubilize phosphorous...
July 19, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28769640/molecular-and-morphological-identification-of-biomphalaria-species-from-the-state-of-s%C3%A3-o-paulo-brazil
#8
Raquel Gardini Sanches Palasio, Marisa Cristina de Almeida Guimarães, Fernanda Pires Ohlweiler, Roseli Tuan
DNA barcoding and morphological characters were used to identify adult snails belonging to the genus Biomphalaria from 17 municipalities in the state of São Paulo, Brazil. The DNA barcode analysis also included twenty-nine sequences retrieved from GenBank. The final data set of 104 sequences of the mitochondrial cytochrome oxidase I (COI) gene was analyzed for K2P intraspecific and interspecific divergences, through tree-reconstruction methods (Neighbor-Joining, Maximum Likelihood and Bayesian inference), and by applying different models (ABGD, bPTP, GMYC) to partition the sequences according to the pattern of genetic variation...
2017: ZooKeys
https://www.readbyqxmd.com/read/28766916/interleukin-18-il-18-is-equally-expressed-in-inflammatory-breast-cancer-and-noninflammatory-locally-advanced-breast-cancer-a-possible-association-with-chemotherapy-response
#9
Marco Antonio Nasser Aguiar, Carlos Wagner S Wanderley, Lívia Maria Soares Nobre, Mateus Rolim Mendes Alencar, Maria do Perpétuo Socorro Saldanha, Alceu Machado Souza, Deysi Viviana Tenazoa Wong, Paulo Goberlânio Barros, Paulo Roberto Carvalho Almeida, Roberto Cesar Pereira Lima-Júnior, Ronaldo Albuquerque Ribeiro
AIM: Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer. The signs of inflammation such as hyperemia and hyperthermia might suggest the possible participation of inflammatory mediators. This study investigates stromal and tumor expression of nuclear factor-kappa B (NF-κB) and interleukin-18 (IL-18) in samples obtained from IBC and noninflammatory locally advanced breast cancer (LABC) and the influence of these markers on patients' prognosis...
August 2, 2017: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28761873/pneumoretroperitoneum-and-sepsis-after-transanal-endoscopic-resection-of-a-rectal-lateral-spreading-tumor
#10
Bruno Augusto Alves Martins, Marcelo de Melo Andrade Coura, Romulo Medeiros de Almeida, Natascha Mourão Moreira, João Batista de Sousa, Paulo Gonçalves de Oliveira
Transanal endoscopic microsurgery is considered a safe, appropriate, and minimally invasive approach, and complications after endoscopic microsurgery are rare. We report a case of sepsis and pneumoretroperitoneum after resection of a rectal lateral spreading tumor. The patient presented with rectal mucous discharge. Colonoscopy revealed a rectal lateral spreading tumor. The patient underwent an endoscopic transanal resection of the lesion. He presented with sepsis of the abdominal focus, and imaging tests revealed pneumoretroperitoneum...
June 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/28759766/metal-toxicity-assessment-by-sentinel-species-of-mangroves-in-situ-case-study-integrating-chemical-and-biomarkers-analyses
#11
Luis Felipe de Almeida Duarte, Caroline Araújo de Souza, Camilo Dias Seabra Pereira, Marcelo Antonio Amaro Pinheiro
Globally, there is a lack of knowledge about tropical ecotoxicology dealing with the potential impact of metal contamination in mangrove ecosystem. This habitat is considered a nursery for several animal species, among them the "uçá"-crab (Ucides cordatus), known as a key species due to its biological and economical importance. This study evaluated the association involving metal contamination (Cd, Cu, Pb, Cr, Mn and Hg) in water, sediment, red-mangrove vegetation (Rhizophora mangle) and tissues of uçá crab, together with its geno-cytotoxic responses, based on micronucleated hemocytes frequency and the retention time of neutral red in lysosomes...
July 28, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28741872/breast-disease-in-men-in-metropolitan-s%C3%A3-o-paulo-brazil
#12
Renata Thaís de Almeida Barbosa, Maria Auxiliadora F Vertamatti, Claudia Arab, Tânia Brusque Crocetta, Ricardo Lencioni Mazzei, Ivo Carelli Filho, Ricardo Faure, Izabella Brandão Mendes, Luiz Carlos de Abreu
Although rare, breast cancer in males represents 1% of all cancer in men, and has shown increasing incidence in 25 years. To analyze age, gender, type of procedure performed and diagnosis of all cases of breast diseases in a public hospital in Sao Paulo, Brazil, with special focus on men. Cross-sectional study of breast surgery in 2010-2014 at Hospital Municipal Universitario de Sao Bernardo do Campo, Brazil. In the period 999 breast surgery were carried out. Patients with benign diseases were about 30 years old and patients with malignant diseases were over 50...
July 25, 2017: Breast Journal
https://www.readbyqxmd.com/read/28738908/barriers-to-and-facilitators-of-ultra-processed-food-consumption-perceptions-of-brazilian-adults
#13
Luara Bellinghausen Almeida, Fernanda Baeza Scagliusi, Ana Clara Duran, Patricia Constante Jaime
OBJECTIVE: To explore how individuals perceive the availability of ultra-processed foods in their neighbourhoods and the barriers to and facilitators of consumption of such foods. DESIGN: A qualitative design was chosen. In-depth, face-to-face semi-structured interviews were conducted and a content analysis was performed. SETTING: São Paulo, Brazil. SUBJECTS: A purposeful sample of adults (n 48), stratified by sex and age group (20-39 years and 40-59 years)...
July 25, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28738632/raman-hyperspectral-imaging-in-conjunction-with-independent-component-analysis-as-a-forensic-tool-for-explosive-analysis-the-case-of-an-atm-explosion
#14
Mariana Ramos Almeida, Lucio Paulo Lima Logrado, Jorge Jardim Zacca, Deleon Nascimento Correa, Ronei Jesus Poppi
In this work, Raman hyperspectral imaging, in conjunction with independent component analysis, was employed as an analytical methodology to detect an ammonium nitrate fuel oil (ANFO) explosive in banknotes after an ATM explosion experiment. The proposed methodology allows for the identification of the ANFO explosive without sample preparation or destroying the sample, at quantities as small as 70μgcm(-2). The explosive was identified following ICA data decomposition by the characteristic nitrate band at 1044cm(-1)...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28732311/solid-and-aqueous-magnetoliposomes-as-nanocarriers-for-a-new-potential-drug-active-against-breast-cancer
#15
Ana Rita O Rodrigues, Pedro M F Mendes, Pedro M L Silva, V A Machado, Bernardo G Almeida, J P Araújo, Maria-João R P Queiroz, Elisabete M S Castanheira, Paulo J G Coutinho
Iron oxide nanoparticles, with diameters around 12nm, were synthesized by coprecipitation method. The magnetic properties indicate a superparamagnetic behavior with a coercive field of 9.7Oe and a blocking temperature of 118K. Both aqueous and solid magnetoliposomes containing magnetite nanoparticles have sizes below 150nm, suitable for biomedical applications. Interaction between both types of magnetoliposomes and models of biological membranes was proven. A new antitumor compound, a diarylurea derivative of thienopyridine, active against breast cancer, was incorporated in both aqueous and solid magnetoliposomes, being mainly located in the lipid membrane...
July 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28724044/alcohol-and-tobacco-use-and-the-diseases-treated-in-general-practice
#16
Maria Flora de Almeida, Filipe Fernandes Ferreira, Mílton de Arruda Martins, Mario Ferreira
Objective: To characterize the use of alcohol and tobacco and correlate both to the diseases of outpatients in a general practice outpatient clinic. Method: The ASSIST (Alcohol, Smoking and Substance Involvement Screening Test) questionnaire was answered by 300 randomly chosen subjects assigned to different groups according to the diseases being treated at the Outpatient General and Teaching Clinic of the Department of Internal Medicine, Hospital das Clínicas of the University of São Paulo's School of Medicine (HC-FMUSP, in the Portuguese acronym), São Paulo, Brazil...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28717838/the-triterpenoid-alpha-beta-amyrin-prevents-the-impaired-aortic-vascular-reactivity-in-high-fat-diet-induced-obese-mice
#17
Flávia Almeida Santos, Karine Maria Martins Bezerra Carvalho, Francisco José Batista-Lima, Paulo Iury Gomes Nunes, Ana Flávia Seraine Custódio Viana, Armenio André de Carvalho Almeida da Silva, Said Gonçalves da Cruz Fonseca, Mariana Helena Chaves, Vietla Satyanarayana Rao, Pedro Jorge Caldas Magalhães, Teresinha Silva de Brito
To characterize the protective effects of the triterpenoid mixture alpha, beta-amyrin (AMY, 20 mg/kg, during 15 days) on the reactivity of isolated aorta of high-fat diet (HFD)-induced obese mice. Male Swiss mice were fed with HFD or normal diet (ND) for 15 weeks. Contractions of thoracic aorta in response to KCl or phenylephrine (PHE) and relaxation by acetylcholine (ACh) or sodium nitroprusside (SNP) were analyzed. HFD-fed mice developed hyperglycemia, hyperlipidemia, and significant body weight gain, parameters prevented by AMY treatment...
July 17, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28714849/proposal-for-a-unified-classification-system-and-nomenclature-of-lagoviruses
#18
Jacques Le Pendu, Joana Abrantes, Stéphane Bertagnoli, Jean-Sébastien Guitton, Ghislaine Le Gall-Reculé, Ana Margarida Lopes, Stéphane Marchandeau, Fernando Alda, Tereza Almeida, Alves Paulo Célio, Juan Bárcena, Galina Burmakina, Esther Blanco, Carlos Calvete, Patrizia Cavadini, Brian Cooke, Kevin Dalton, Miguel Delibes Mateos, Wieslaw Deptula, John Sebastian Eden, Fang Wang, Catarina C Ferreira, Paula Ferreira, Pilar Foronda, David Gonçalves, Dolores Gavier-Widén, Robin Hall, Beata Hukowska-Szematowicz, Peter Kerr, John Kovaliski, Antonio Lavazza, Jackie Mahar, Alexander Malogolovkin, Raquel M Marques, Sara Marques, Aaron Martin-Alonso, Pedro Monterroso, Sacramento Moreno, Greg Mutze, Aleksija Neimanis, Paulina Niedzwiedzka-Rystwej, David Peacock, Francisco Parra, Mara Rocchi, Carlos Rouco, Nathalie Ruvoën-Clouet, Eliane Silva, Diogo Silvério, Tanja Strive, Gertrudes Thompson, Beata Tokarz-Deptula, Pedro Esteves
Lagoviruses belong to the Caliciviridae family. They were first recognized as highly pathogenic viruses of the European rabbit (Oryctolagus cuniculus) and European brown hare (Lepus europaeus) that emerged in the 1970-1980s, namely, rabbit haemorrhagic disease virus (RHDV) and European brown hare syndrome virus (EBHSV), according to the host species from which they had been first detected. However, the diversity of lagoviruses has recently expanded to include new related viruses with varying pathogenicity, geographic distribution and host ranges...
July 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28707994/do-craniopharyngioma-molecular-signatures-correlate-with-clinical-characteristics
#19
Sacit Bulent Omay, Yu-Ning Chen, Joao Paulo Almeida, Armando Saul Ruiz-Treviño, John A Boockvar, Philip E Stieg, Jeffrey P Greenfield, Mark M Souweidane, Ashutosh Kacker, David J Pisapia, Vijay K Anand, Theodore H Schwartz
OBJECTIVE Exome sequencing studies have recently demonstrated that papillary craniopharyngiomas (PCPs) and adamantinomatous craniopharyngiomas (ACPs) have distinct genetic origins, each primarily driven by mutually exclusive alterations: either BRAF ( V600E), observed in 95% of PCPs, or CTNNB1, observed in 75%-96% of ACPs. How the presence of these molecular signatures, or their absence, correlates with clinical, radiographic, and outcome variables is unknown. METHODS The pathology records for patients who underwent surgery for craniopharyngiomas between May 2000 and March 2015 at Weill Cornell Medical College were reviewed...
July 14, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28693884/the-flavonoid-rutin-modulates-microglial-macrophage-activation-to-a-cd150-cd206-m2-phenotype
#20
Alessandra Bispo da Silva, Paulo Lucas Cerqueira Coelho, Jessika Alves Oliveira Amparo, Monique Marylin Alves de Almeida Carneiro, Julita Maria Pereira Borges, Cleide Dos Santos Souza, Maria de Fátima Dias Costa, Miriam Mecha, Carmen Guaza Rodriguez, Victor Diogenes Amaral da Silva, Silvia Lima Costa
Rutin is a glycosylated flavonoid present in many fruits and plants that has been demonstrated to have anti-inflammatory and antioxidant properties. However, little is known about the mechanisms underlying microglial activation and its effects on the regulation of cytokines and chemokines associated with inflammatory responses in the central nervous system. In this study we examined the effect of rutin on resting or lipopolysaccharide (LPS)-stimulated microglia and characterized their modulation to an activated M1 phenotype or an alternatively activated M2 phenotype...
July 8, 2017: Chemico-biological Interactions
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