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Paulo Almeida

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https://www.readbyqxmd.com/read/28300914/nevus-lipomatosus-cutaneous-superficialis
#1
Gustavo de Sá Menezes Carvalho, Silvana Maria de Morais Cavalcanti, Alzinira Souza Herênio, Márcia Almeida Galvão Teixeira, Eliane Ruth Barbosa de Alencar, Sergio Paulo Mendes Gonçalves
We report a case of nevus lipomatosus cutaneous superficialis of Hoffman-Zurhelle (NCLS), with multiple lesions, in a ten-year-old child. The NLCS is considered rare. The classical clinical presentation is characterized by multiple skin-colored or yellowish papules and nodules, which can have a linear distribution. Histologically, it is characterized by the presence of mature ectopic adipocytes in the dermis. The main therapeutic option is surgical excision. The classical Nevus lipomatosus cutaneous superficialis is reported in this case...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300887/linear-iga-and-igg-bullous-dermatosis
#2
Karina de Almeida Pinto Fernandes, Kely Hernández Galvis, Anndressa Camillo da Matta Setubal Gomes, Osvania Maris Nogueira, Paulo Antônio Oldani Felix, Thiago Jeunon de Sousa Vargas
Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300708/clinical-outcome-tumor-recurrence-and-causes-of-death-a-long-term-follow-up-of-surgically-treated-meningiomas
#3
Antonio Nogueira de Almeida, Benedito Jamilson Araújo Pereira, Paulo Henrique Pires Aguiar, Wellingson Silva Paiva, Hector Navarro Cabrera, Clemar Corrêa da Silva, Manoel Jacobsen Teixeira, Suely Kazue Nagahashi Marie
OBJECTIVE: The medical literature still lacks information about the impacts of surgery and adjuvant treatment on the life of patients with meningioma. The clinical outcome, timing of tumor recurrence, and causes of death are often overlooked. The paper evaluates these data taking into account tumor localization and histological grade. METHODS: The article is a cross-sectional study of patients operated on between 2000 and 2014 in a single institution. The series has 593 adult patients (442 females and 151 males) and follow-up of 68...
March 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28278104/three-dimensional-oil-dispersion-model-in-campos-basin-brazil
#4
Bernardo Lopes Almeida de Oliveira, Theodoro Antoun Netto, Luiz Paulo de Freitas Assad
This paper presents the physical and mathematical formulation of a three-dimensional oil dispersion model that calculates the trajectory from the seafloor to the sea surface, its assumptions and constraints. It was developed by researchers that are familiar with oil spill dispersion and mathematical analysis. Oil dispersion is calculated through two computational routines. The first calculates the vertical dispersion along the water column and resamples the droplets when the oil reaches the surface. The second calculates the surface displacement of the spill...
February 22, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28274807/virulence-genes-and-genetic-relationship-of-l-monocytogenes-isolated-from-human-and-food-sources-in-brazil
#5
Rosana Macedo de Almeida, André Victor Barbosa, Rodrigo de Castro Lisbôa, André Felipe das Mercês Santos, Ernesto Hofer, Deyse Christina Vallim, Cristina Barroso Hofer
The herein presented assay provided a bacteriological and molecular characterization of 100 samples of L. monocytogenes isolated from human (43) and food (57) sources, from several regions of Brazil, and collected between 1975 and 2013. Antigenic characterization defined 49% of serotype 4b samples, followed by 28% of serotype 1/2b, 14% of serotype 1/2c, 8% of serotype 1/2a, and 1% of serotype 3b. Both type of samples from human and food origin express the same serotype distribution. Multiplex PCR analysis showed 13 strains of type 4b with the amplification profile 4b-VI (Variant I)...
March 5, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28268114/s-mansoni-t-cruzi-co-infection-modulates-arginase-1-inos-expression-liver-and-heart-disease-in-mice
#6
João Paulo Ferreira Rodrigues, Ivo Santana Caldas, Reggiani Vilela Gonçalves, Leonardo Augusto Almeida, Raquel Lopes Martins Souza, Rômulo Dias Novaes
Although Schistosoma species and Trypanosoma cruzi share common endemic areas, co-infections by these parasites remains overlooked. By using a murine model of S. mansoni and T. cruzi co-infection, we investigated if and to what extent these infections might interact to change the pathological outcomes typically observed when the host is infected by a single parasite species. Swiss mice were randomized into four groups: uninfected (NI) and those infected by S. mansoni (SM), T. cruzi (TC) or co-infected (SM + TC)...
March 4, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28266237/frozen-embryo-transfer-cycles-in-women-with-deep-endometriosis
#7
George Queiroz Vaz, Alessandra Viviane Evangelista, Maria Cecilia Almeida Cardoso, Paulo Gallo, Maria Cecilia Erthal, Marco Aurelio Pinho Oliveira
OBJECTIVE: To compare the transfer pregnancy rates with frozen embryos from patients with deep endometriosis and non-endometriosis patients. METHODS: We conducted a retrospective cohort study of review of medical records of 181 women aged 18-40 years, undergoing transfer of frozen embryos into a fertility center. The data collected was from January 2007 to December 2013. RESULTS: Regarding the patients with endometriosis, there was no statistical difference in proportion to compare polycystic ovarian syndrome, male factor, tubal factor and unexplained infertility...
March 7, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28254548/brachio-brachial-arteriovenous-fistula-superficialization-with-short-skip-incisions
#8
António Norton de Matos, Clemente Neves Sousa, Paulo Almeida, José Queirós, Duarte Rego, Gabriela Teixeira, Luís Loureiro, Sérgio Teixeira
The exhaustion of superficial venous patrimony or reduced diameter of superficial veins usually prevent patients from having an arteriovenous fistula created. In such cases, utilizing deep vessels can be a more viable option as opposed to an arteriovenous graft. We describe a new approach for the brachio-brachial arteriovenous fistula creation technique. It consists of three small incisions, thus causing minimal surgical damage. We have found it to be better tolerated by the patients and well received by dialysis nurses...
February 27, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28241780/thromboelastometry-versus-standard-coagulation-tests-versus-restrictive-protocol-to-guide-blood-transfusion-prior-to-central-venous-catheterization-in-cirrhosis-study-protocol-for-a-randomized-controlled-trial
#9
Leonardo Lima Rocha, Camila Menezes Souza Pessoa, Ary Serpa Neto, Rogerio Ruscitto do Prado, Eliezer Silva, Marcio Dias de Almeida, Thiago Domingos Correa
BACKGROUND: Liver failure patients have traditionally been empirically transfused prior to invasive procedures. Blood transfusion is associated with immunologic and nonimmunologic reactions, increased risk of adverse outcomes and high costs. Scientific evidence supporting empirical transfusion is lacking, and the best approach for blood transfusion prior to invasive procedures in cirrhotic patients has not been established so far. The aim of this study is to compare three transfusion strategies (routine coagulation test-guided - ordinary or restrictive, or thromboelastometry-guided) prior to central venous catheterization in critically ill patients with cirrhosis...
February 27, 2017: Trials
https://www.readbyqxmd.com/read/28241038/spatial-clustering-and-local-risk-of-leprosy-in-s%C3%A3-o-paulo-brazil
#10
Antônio Carlos Vieira Ramos, Mellina Yamamura, Luiz Henrique Arroyo, Marcela Paschoal Popolin, Francisco Chiaravalloti Neto, Pedro Fredemir Palha, Severina Alice da Costa Uchoa, Flávia Meneguetti Pieri, Ione Carvalho Pinto, Regina Célia Fiorati, Ana Angélica Rêgo de Queiroz, Aylana de Souza Belchior, Danielle Talita Dos Santos, Maria Concebida da Cunha Garcia, Juliane de Almeida Crispim, Luana Seles Alves, Thaís Zamboni Berra, Ricardo Alexandre Arcêncio
BACKGROUND: Although the detection rate is decreasing, the proportion of new cases with WHO grade 2 disability (G2D) is increasing, creating concern among policy makers and the Brazilian government. This study aimed to identify spatial clustering of leprosy and classify high-risk areas in a major leprosy cluster using the SatScan method. METHODS: Data were obtained including all leprosy cases diagnosed between January 2006 and December 2013. In addition to the clinical variable, information was also gathered regarding the G2D of the patient at diagnosis and after treatment...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28240141/preparation-characterization-and-biocompatibility-studies-of-thermoresponsive-eyedrops-based-on-the-combination-of-nanostructured-lipid-carriers-nlc-and-the-polymer-pluronic-f-127-for-controlled-delivery-of-ibuprofen
#11
Hugo Almeida, Paulo Lobão, Christian Frigerio, Joel Fonseca, Renata Silva, José Manuel Sousa Lobo, Maria Helena Amaral
CONTEXT: Nanostructured lipid carrier (NLC) dispersions present low viscosity and poor mucoadhesive properties, which reduce the pre-corneal residence time and consequently, the bioavailability of ocular drugs. OBJECTIVE: The aim of this study was to prepare thermoresponsive eyedrops based on the combination of lipid nanoparticles and a thermoresponsive polymer with mucomimetic properties (Pluronic® F-127). MATERIALS AND METHODS: NLCi dispersions were prepared based on the melt-emulsification and ultrasonication technique...
May 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28238773/inhibition-of-the-tetk-efflux-pump-by-the-essential-oil-of-chenopodium-ambrosioides-l-and-%C3%AE-terpinene-against-staphylococcus-aureus-is-58
#12
Paulo W Limaverde, Fábia F Campina, Francisco A B da Cunha, Francidalva D Crispim, Fernando G Figueredo, Luciene F Lima, Cícera Datiane de M Oliveira-Tintino, Yedda M L S de Matos, Maria Flaviana B Morais-Braga, Irwin R A Menezes, Valdir Q Balbino, Henrique D M Coutinho, José P Siqueira-Júnior, Jackson R G S Almeida, Saulo R Tintino
The use of natural products is crucial to suppress the development of these micro-organisms and to reduce the concentration necessary to inhibit these microrganisms, reducing the toxicity risks also. In this study, the essential oil from Chenopodium ambrosioides Leaves and its main constituent α-Terpinene were used in the antibacterial and potentiating activity of antibiotics and ethidium bromide assays, against the bacterial strains Staphylococcus aureus IS-58, carriers of efflux pumps. The Minimum Inhibitory Concentration (MIC) was determined using a microdilution method...
February 23, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28231394/adaptive-divergence-in-wine-yeasts-and-their-wild-relatives-suggests-a-prominent-role-for-introgressions-and-rapid-evolution-at-non-coding-sites
#13
Pedro Almeida, Raquel Barbosa, Douda Bensasson, Paula Gonçalves, José Paulo Sampaio
In Saccharomyces cerevisiae, the main yeast in wine fermentation, the opportunity to examine divergence at the molecular level between a domesticated lineage and its wild counterpart arose recently due to the identification of the closest relatives of wine strains, a wild population associated with Mediterranean oaks. Since genomic data is available for a considerable number of representatives belonging to both groups, we used population genomics to estimate the degree and distribution of nucleotide variation between wine yeasts and their closest wild relatives...
February 23, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28226063/pelvic-floor-rehabilitation-program-report-of-10-years-of-experience
#14
Maria Helena Baena de Moraes Lopes, Juliana Neves da Costa, Júnia Leonne Dourado de Almeida Lima, Lea Dolores Reganhan de Oliveira, Aletha Silva Caetano
Objective: to relate the creation, experience of establishment and service performed in the Pelvic Floor Rehabilitation Program [(PRAP)], a project of the School of Nursing of University of Campinas (UNICAMP), developed at a health unity in Campinas, São Paulo, Brazil. Results: this Program appeared due to the high demand of patients with urinary incontinence (UI) and need of formation or qualification of professionals to serve those customers and multiply the actions at other health unities...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28215251/the-association-between-caffeine-consumption-and-objective-sleep-variables-is-dependent-on-adora2a-c-1083t-c-genotypes
#15
Rafael Almeida Nunes, Diego Robles Mazzotti, Camila Hirotsu, Monica L Andersen, Sergio Tufik, Lia Bittencourt
OBJECTIVE: To verify the association between c.1083T>C polymorphism in the adenosine receptor A2A gene (ADORA2A) and objective sleep, as well as the correlation between caffeine consumption, sleep parameters, and electroencephalographic spectral power in a large, population-based sample from São Paulo, Brazil. METHODS: This study was conducted in participants of the São Paulo Epidemiologic Sleep Study (EPISONO), a large, population-based survey consisting of a representative sample of the inhabitants of the city from São Paulo, Brazil, according to sex, age (20-80 years), and socioeconomic status in the year 2007...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28191024/recent-trends-in-pharmacological-activity-of-alkaloids-in-animal-colitis-potential-use-for-inflammatory-bowel-disease
#16
REVIEW
Ana Cristina Alves de Almeida, Felipe Meira de-Faria, Ricardo José Dunder, Luis Paulo Bognoni Manzo, Alba Regina Monteiro Souza-Brito, Anderson Luiz-Ferreira
Inflammatory bowel disease (IBD) is a chronic and disrupted inflammation of the gastrointestinal tract. IBD have two main conditions, Crohn's disease and ulcerative colitis, and have been extensively investigated in recent years. Antibiotics derived from salicylates, steroids, immunosuppressors, and anti-TNF therapy are part of the therapeutic arsenal for IBD. However, very often patients stop responding to treatments over the time. In this context, searching for alternative agents is crucial for IBD clinical management...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28189083/structure-based-design-synthesis-and-antitumoral-evaluation-of-enulosides
#17
Jonh A M Santos, Cosme S Santos, Claudia L A Almeida, Thiago D S Silva, João R Freitas Filho, Gardenia C G Militão, Teresinha G da Silva, Carlos H B da Cruz, Juliano C R Freitas, Paulo H Menezes
Enulosides, carbohydrate derivatives containing an α,β-unsaturated carbonyl unit, were designed and obtained in high yields and isomeric purity. All synthesized compounds exhibited antitumoral activity in micromolar range against four tested tumor cells lines, being the best results observed for HL-60 cells. These compounds open new possibilities to prepare an array of more active, site-specific or selective antitumor agents. 2016 Elsevier Ltd. All rights reserved.
January 24, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28188835/automated-pulse-discrimination-of-two-freely-swimming-weakly-electric-fish-and-analysis-of-their-electrical-behavior-during-dominance-contest
#18
Rafael T Guariento, Thiago S Mosqueiro, Paulo Matias, Vinicius B Cesarino, Lirio O B Almeida, Jan F W Slaets, Leonardo P Maia, Reynaldo D Pinto
Electric fishes modulate their electric organ discharges with a remarkable variability. Some patterns can be easily identified, such as pulse rate changes, offs and chirps, which are often associated with important behavioral contexts, including aggression, hiding and mating. However, these behaviors are only observed when at least two fish are freely interacting. Although their electrical pulses can be easily recorded by non-invasive techniques, discriminating the emitter of each pulse is challenging when physically similar fish are allowed to freely move and interact...
February 7, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28185126/zika-virus-and-neuroscience-the-need-for-a-translational-collaboration
#19
Lavínia Schuler-Faccini, Paulo Roehe, Eduardo R Zimmer, André Quincozes-Santos, Adriano M de Assis, Elizabeth Obino Cirne Lima, Jorge Almeida Guimarães, Cesar Victora, Vivaldo Moura Neto, Diogo O Souza
Zika virus (ZIKV) has become a major challenge for scientists and health agencies. ZIKV's involvement with human fetal microcephaly and Guillain-Barré syndrome and its transmission through Aedes africanus and Aedes aegypti mosquitos highlighted the epidemiological and neurological risks associated to ZIKV infection. In 2013, ZIKV arrives in Brazil but the first outbreak in the country was reported in 2015. Here, we used the Web of Science as a search tool for comparing the evolution of world and Brazilian scientific research on dengue virus (DENV)-also present in mosquito-, ZIKV and microcephaly...
February 9, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28182237/chromosomal-evolution-and-cytotaxonomy-in-wrasses-perciformes-labridae
#20
Leandro A H Almeida, Lorena A Nunes, Jamille A Bitencourt, Wagner F Molina, Paulo R A M Affonso
No abstract text is available yet for this article.
February 9, 2017: Journal of Heredity
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