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nutritional treatment diabetes

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https://www.readbyqxmd.com/read/29928894/high-fat-diet-unveils-an-enhancer-element-at-the-ped-pea-15-gene-responsible-for-epigenetic-memory-in-skeletal-muscle
#1
Viviana Vastolo, Immacolata Cristina Nettore, Marco Ciccarelli, Luigi Albano, Gregory Alexander Raciti, Michele Longo, Francesco Beguinot, Paola Ungaro
BACKGROUND: The impact of nutrition on the evolution towards type 2 diabetes has recently received increasing attention because of the effect on chromatin structure and gene expression. PURPOSE: Evaluate the effect of high-fat diet on chromatin remodelling and expression of Ped/Pea-15, a gene commonly overexpressed in individuals at risk of type 2 diabetes. METHODS: We used mouse and cell models to investigate Ped/Pea-15 transcriptional regulation by high-fat diet and glucose, respectively...
June 18, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29927530/nutrition-implications-for-long-term-survivors-of-pancreatic-cancer-surgery
#2
REVIEW
Maria Q B Petzel, Leah Hoffman
With slowly increasing survival rates in pancreatic cancer and international consensus guidelines recommending surgical resection of premalignant lesions, survival post-pancreatic resection is increasing. With longer survival time, the significant comorbidities of such major surgery have far-reaching effects on the nutrition status of the survivor of pancreatic cancer. This review describes the many nutrition-related side effects of pancreatic surgery, including the development of pancreatic enzyme insufficiency, micronutrient deficiencies, diabetes, fatty liver, and metabolic bone disease...
October 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29907450/altered-maternal-and-placental-lipid-metabolism-and-fetal-fat-development-in-obesity-current-knowledge-and-advances-in-non-invasive-assessment
#3
Flavien Delhaes, Stephanie A Giza, Tianna Koreman, Genevieve Eastabrook, Charles A McKenzie, Samantha Bedell, Timothy R H Regnault, Barbra de Vrijer
Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated with pregnancy complications such as preeclampsia and gestational diabetes, and offspring long-term metabolic health is impacted as the consequence of altered fetal growth, physiology and often iatrogenic prematurity. The metabolic changes associated with maternal obesity and/or the consumption of a high-fat diet effecting maternal lipid profiles and metabolism have also been documented to specifically affect placental function and may underlie changes in fetal development and life course disease risk...
May 26, 2018: Placenta
https://www.readbyqxmd.com/read/29903481/performance-of-stochastic-targeted-blood-glucose-control-protocol-by-virtual-trials-in-the-malaysian-intensive-care-unit
#4
Ummu K Jamaludin, Fatanah M Suhaimi, Normy Norfiza Abdul Razak, Azrina Md Ralib, Mohd Basri Mat Nor, Christopher G Pretty, Luqman Humaidi
BACKGROUND AND OBJECTIVE: Blood glucose variability is common in healthcare and it is not related or influenced by diabetes mellitus. To minimise the risk of high blood glucose in critically ill patients, Stochastic Targeted Blood Glucose Control Protocol is used in intensive care unit at hospitals worldwide. Thus, this study focuses on the performance of stochastic modelling protocol in comparison to the current blood glucose management protocols in the Malaysian intensive care unit...
August 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29895254/investigating-information-needs-of-saudi-diabetic-patients
#5
Irfan Anjum Manarvi, Nader Mahr Matta
BACKGROUND: Studies have shown that newly diagnosed diabetic patients need a lot of information about medical examinations, checkups, tests and precautions for its control besides its disastrous effects on heart, kidneys, eyes, foot and nerves etc. Patients in Saudi Arabia are generally not aware of most of the information they may need which is one the major reasons of its increasing number of patients. Past studies conducted are based on clinical data of hospitals and health care centers only discussed its effects...
June 11, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29888116/dietetics-practice-in-the-unique-culturally-diverse-pacific-island-region
#6
Cynthia L Endrizal, Marie Kainoa Fialkowski, Jim Davis, Sarah Yuan, Rachel Novotny, Treena Wasonti Io Delormier, Beatriz Rodriguez
The Pacific Island region is geographically the most isolated region in the world representing a diverse population of indigenous peoples, migrated groups and new-comers. Rates of chronic disease are predominately high in populations identified as Pacific Islander. The practice of dietetics, defined as nutrition education for the prevention of disease and medical nutrition therapy for the treatment of chronic diseases, proves challenging with the unique cultural diversity in the region. There is a need to describe dietetics practice, populations served, and needs for resources identified by nutrition-related topic and cultural relevance for Registered Dietitian Nutritionists in the Pacific Island region...
June 2018: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/29875971/prevalence-and-factors-associated-with-metabolic-syndrome-in-an-urban-population-of-adults-living-with-hiv-in-nairobi-kenya
#7
Catherine Nduku Kiama, Joyce Njeri Wamicwe, Elvis Omondi Oyugi, Mark Odhiambo Obonyo, Jane Githuku Mungai, Zeinab Gura Roka, Ann Mwangi
Introduction: Metabolic syndrome affects 20-25% of the adult population globally. It predisposes to cardiovascular disease and Type 2 diabetes. Studies in other countries suggest a high prevalence of metabolic syndrome among HIV-infected patients but no studies have been reported in Kenya. The objective of this study was to assess the prevalence and factors associated with metabolic syndrome in adult HIV-infected patients in an urban population in Nairobi, Kenya. Methods: In a cross-sectional study design, conducted at Riruta Health Centre in 2016, 360 adults infected with HIV were recruited...
2018: Pan African Medical Journal
https://www.readbyqxmd.com/read/29870029/metformin-added-to-intensive-insulin-therapy-improves-metabolic-control-in-patients-with-type-1-diabetes-and-excess-body-fat
#8
Agnieszka Zawada, Dariusz Naskręt, Paweł Burchardt, Paweł Niedźwiecki, Stanisław Piłaciński, Bogna Wierusz-Wysocka, Marian Grzymisławski, Dorota Zozulińska-Ziółkiewicz
INTRODUCTION Bad nutritional habits and administration of insulin in supraphysiological doses lead to the development of insulin resistance and poor metabolic control in patients with type 1 diabetes. Accumulation of visceral fat is the main cause of the decrease in insulin sensitivity. OBJECTIVES We aimed to evaluate changes in anthropometric parameters, indirect measures of insulin resistance, and safety of treatment with metformin added to intensive insulin therapy in patients with type 1 diabetes and excess body fat...
May 30, 2018: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29868373/diabetes-diagnosis-and-management-among-insured-adults-across-metropolitan-areas-in-the-u-s
#9
Wenya Yang, Timothy M Dall, Eleonora Tan, Erin Byrne, William Iacobucci, Ritashree Chakrabarti, F Ellen Loh
This study provides diabetes-related metrics for the 50 largest metropolitan areas in the U.S. in 2012-including prevalence of diagnosed and undiagnosed diabetes, insurance status of the population with diabetes, diabetes medication use, and prevalence of poorly controlled diabetes. Diabetes prevalence estimates were calculated using cross-sectional data combining the Behavioral Risk Factor Surveillance System, American Community Survey, National Nursing Home Survey, Census population files, and National Health and Nutrition Examination Survey...
June 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29860978/characterization-of-the-degree-of-food-processing-in-relation-with-its-health-potential-and-effects
#10
Anthony Fardet
Up today technological processes are intended to produce safe and palatable food products. Yet, it is also expected that processing produces healthy and sustainable foods. However, due to the dramatic increase of chronic diseases prevalence worldwide, i.e., obesity, type 2 diabetes, cardiovascular diseases, and some cancers, ultraprocessing has been pointed out as producing unhealthy foods, rich in energy and poor in protective micronutrients and fiber, i.e., "empty" calories. Indeed the 1980s saw massive arrivals of ultraprocessed foods in supermarkets, i...
2018: Advances in Food and Nutrition Research
https://www.readbyqxmd.com/read/29859847/altered-pancreatic-islet-morphology-and-function-in-sglt1-knockout-mice-on-a-glucose-deficient-fat-enriched-diet
#11
Markus Mühlemann, Daniela Zdzieblo, Alexandra Friedrich, Constantin Berger, Christoph Otto, Heike Walles, Hermann Koepsell, Marco Metzger
OBJECTIVES: Glycemic control by medical treatment represents one therapeutic strategy for diabetic patients. The Na+-d-glucose cotransporter 1 (SGLT1) is currently of high interest in this context. SGLT1 is known to mediate glucose absorption and incretin secretion in the small intestine. Recently, inhibition of SGLT1 function was shown to improve postprandial hyperglycemia. In view of the lately demonstrated SGLT1 expression in pancreatic islets, we investigated if loss of SGLT1 affects islet morphology and function...
May 23, 2018: Molecular Metabolism
https://www.readbyqxmd.com/read/29858905/a-novel-mutation-in-the-proopiomelanocortin-pomc-gene-of-a-hispanic-child-metformin-treatment-shows-a-beneficial-impact-on-the-body-mass-index
#12
Mark A Hilado, Ruvdeep S Randhawa
BACKGROUND: Proopiomelanocortin (POMC) is a complex polypeptide that produces a variety of biologically active substances via cleavage in a tissue-specific manner [Challis BG, Millington GW. Proopiomelanocortin deficiency. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle, 1993-2018], yielding several products including adrenocorticotrophic (ACTH) and melanocyte stimulating hormones (MSH). These peptides have roles in the regulation of food intake, energy homeostasis, adrenal steroidogenesis, melanocyte stimulation and immune modulation...
June 2, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29858369/trends-in-prevalence-and-control-of-hypertension-according-to-the-2017-american-college-of-cardiology-american-heart-association-acc-aha-guideline
#13
Kirsten S Dorans, Katherine T Mills, Yang Liu, Jiang He
BACKGROUND: Hypertension is a major risk factor for cardiovascular disease and all-cause mortality. Compared with prior guidelines, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guideline recommends lower blood pressure thresholds for defining hypertension, for initiating antihypertensive medication, and for antihypertensive medication treatment goals. METHODS AND RESULTS: To better understand potential impacts of the 2017 guideline, we studied trends in mean systolic blood pressure and diastolic blood pressure, prevalence and burden of hypertension, and proportion of controlled hypertension in the US adult population aged ≥20 from 1999 through 2016...
June 1, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29851322/-type-1-diabetes-physical-activity-and-novel-technology
#14
Christophe Kosinski, Olivier Le Dizès, Giacomo Gastaldi, Magali Andrey, Francesca Amati, François R Jornayvaz, Jardena J Puder
Physical activity is recommended for all patients with diabetes, but it is important to be particularly attentive in patients with type 1 diabetes. Because of their treatment, these patients have a higher risk of hypoglycemia. The challenge for both caregivers and the patient is to find the best possible strategy to practice the desired physical activity without any significant hypo- or hyperglycemia. Thus, an adaptation of the insulin and/or nutritional treatment is necessary, depending on the type, intensity and duration of the physical activity...
May 30, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29800598/vegetarian-dietary-patterns-and-cardiovascular-disease
#15
REVIEW
Hana Kahleova, Susan Levin, Neal D Barnard
Cardiovascular (CV) disease (CVD) is the leading global cause of mortality, being responsible for 46% of non-communicable disease deaths. It has been estimated that about 85.6 million Americans are living with some form of CVD, which continues to rise. Healthy lifestyle choices may reduce the risk of myocardial infarction by more than 80%, with nutrition playing a key role. Vegetarian dietary patterns reduce CVD mortality and the risk of coronary heart disease (CHD) by 40%. Plant-based diets are the only dietary pattern to have shown reversal of CHD...
May 22, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29797375/medical-nutrition-treatment-of-women-with-gestational-diabetes-mellitus-by-a-telemedicine-system-based-on-smartphones
#16
Ping Yang, Wenpin Lo, Zong-Lin He, Xiao-Min Xiao
AIM: To explore whether WeChat platform-based treatment of women with gestational diabetes mellitus (GDM) reduces the risk of perinatal complications and explore factors affecting gestational age at delivery. METHODS: Pregnant women with GDM (n = 107) and normal glucose tolerance (n =50, group C) according to oral glucose tolerance test (OGTT) results during gestational weeks 24-28 were included. Women with GDM were divided into groups A (n =57) and B (n =50) according to informed consent...
May 23, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29793315/nanotherapeutics-an-insight-into-healthcare-and-multi-dimensional-applications-in-medical-sector-of-the-modern-world
#17
REVIEW
Minakshi Prasad, Upendra P Lambe, Basanti Brar, Ikbal Shah, Manimegalai J, Koushlesh Ranjan, Rekha Rao, Sunil Kumar, Sheefali Mahant, Sandip Kumar Khurana, Hafiz M N Iqbal, Kuldeep Dhama, Jyoti Misri, Gaya Prasad
In recent years nanotechnology has revolutionized the healthcare strategies and envisioned to have a tremendous impact to offer better health facilities. In this context, medical nanotechnology involves design, fabrication, regulation, and application of therapeutic drugs and devices having a size in nano-range (1-100 nm). Owing to the revolutionary implications in drug delivery and gene therapy, nanotherapeutics has gained increasing research interest in the current medical sector of the modern world. The areas which anticipate benefits from nano-based drug delivery systems are cancer, diabetes, infectious diseases, neurodegenerative diseases, blood disorders and orthopedic problems...
January 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29790775/dental-periodontal-and-salivary-conditions-in-diabetic-children-associated-with-metabolic-control-variables-and-nutritional-plan-adherence
#18
C Y Díaz Rosas, E Cárdenas Vargas, J E Castañeda-Delgado, L A Aguilera-Galaviz, M C Aceves Medina
AIM: Diabetes mellitus is a chronic disease that has manifestations other than alterations in endocrine regulation or in metabolic pathways. Several diseases of the oral cavity have been associated with diabetes mellitus type 1 and 2 in young people according to their evolution. Scarce information exists regarding the role of diabetes and its association with the oral health status in paediatric diabetic patients. The aims of the study were to assess the quality of saliva, saliva acidogenicity, dental caries experience, fluorosis and periodontal status in diabetic patients and to evaluate their relationship with metabolic control variables and nutritional plan adherence...
June 2018: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29785173/phytochemicals-that-influence-gut-microbiota-as-prophylactics-and-for-the-treatment-of-obesity-and-inflammatory-diseases
#19
REVIEW
Lucrecia Carrera-Quintanar, Rocío I López Roa, Saray Quintero-Fabián, Marina A Sánchez-Sánchez, Barbara Vizmanos, Daniel Ortuño-Sahagún
Gut microbiota (GM) plays several crucial roles in host physiology and influences several relevant functions. In more than one respect, it can be said that you "feed your microbiota and are fed by it." GM diversity is affected by diet and influences metabolic and immune functions of the host's physiology. Consequently, an imbalance of GM, or dysbiosis, may be the cause or at least may lead to the progression of various pathologies such as infectious diseases, gastrointestinal cancers, inflammatory bowel disease, and even obesity and diabetes...
2018: Mediators of Inflammation
https://www.readbyqxmd.com/read/29783969/association-between-thyroid-hormones-and-the-components-of-metabolic-syndrome
#20
Jieun Jang, Youngsook Kim, Jaeyong Shin, Sang Ah Lee, Young Choi, Eun-Cheol Park
BACKGROUND: Thyroid hormones are known to have direct and indirect effects on metabolism. Individuals with metabolic syndrome, a disease that is growing in incidence at a rapid rate, are at higher risk for cardiovascular disease, diabetes, and cancer. The aim of this study was to identify whether significant correlations exist between thyroid hormone levels and components of the metabolic syndrome in the general population of Korea. METHODS: The data were collected from the sixth Korea National Health and Nutrition Examination Surveys from 2013 to 2015...
May 21, 2018: BMC Endocrine Disorders
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