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https://www.readbyqxmd.com/read/28810979/women-veterans-a-population-at-risk-for-fibromyalgia-the-associations-between-fibromyalgia-symptoms-and-quality-of-life
#1
Rita F D'Aoust, Alicia Gill Rossiter, Amanda Elliott, Ming Ji, Cecile Lengacher, Maureen Groer
BACKGROUND: The Institute of Federal Health Care recently published an executive summary from a round table discussion indicating that active duty and retired female military personnel are at high risk for adverse health outcomes unique to military service including complications related to post-traumatic stress disorder (PTSD), unreported sexual trauma, and musculoskeletal problems. In 2008, the Institute of Medicine began to review, evaluate, and summarize the literature on health outcomes in Gulf War-deployed and found sufficient evidence of a causal relationship with PTSD and suggestive evidence of an association with fibromyalgia (FM)...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28805432/strain-dependent-sex-differences-in-a-long-term-forced-swim-paradigm
#2
José Colom-Lapetina, Sabrina L Begley, Megan E Johnson, Kristina J Bean, Whitney N Kuwamoto, Rebecca M Shansky
Women are twice as likely as men to suffer from trauma- and stressor-related disorders. The development of improved therapeutic interventions is contingent upon a more complete grasp of both the neural and behavioral dynamics of the stress response in females. The rodent forced swim test (FST) is a valuable animal model for exploring the neurobiological mechanisms responsible for selection of active and passive responses to inescapable stressors, but it is often neglected in 2-day FST studies is the dissociation of innate (Day 1) versus learned (Day 2) coping responses...
August 14, 2017: Behavioral Neuroscience
https://www.readbyqxmd.com/read/28795135/male-and-female-mice-lacking-neuroligin-3-modify-the-behavior-of-their-wild-type-littermates
#3
Shireene Kalbassi, Sven O Bachmann, Ellen Cross, Victoria H Roberton, Stéphane J Baudouin
In most mammals, including humans, the postnatal acquisition of normal social and nonsocial behavior critically depends on interactions with peers. Here we explore the possibility that mixed-group housing of mice carrying a deletion of Nlgn3, a gene associated with autism spectrum disorders, and their wild-type littermates induces changes in each other's behavior. We have found that, when raised together, male Nlgn3 knockout mice and their wild-type littermates displayed deficits in sociability. Moreover, social submission in adult male Nlgn3 knockout mice correlated with an increase in their anxiety...
July 2017: ENeuro
https://www.readbyqxmd.com/read/28781959/structure-based-design-of-ferritin-nanoparticle-immunogens-displaying-antigenic-loops-of-neisseria-gonorrhoeae
#4
Liqin Wang, Daniel Xing, Adriana Le Van, Ann E Jerse, Shuishu Wang
Effective vaccines are urgently needed to combat gonorrhea, a common sexually transmitted bacterial infection, for which treatment options are diminishing due to rapid emergence of antibiotic resistance. We have used a rational approach to the development of gonorrhea vaccines, and genetically engineered nanoparticles to present antigenic peptides of Neisseria gonorrhoeae, the causative agent of gonorrhea. We hypothesized that the ferritin nanocage could be used as a platform to display an ordered array of N...
August 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/28762121/-in-patient-hospital-care-of-selected-sexual-disorders-an-analysis-of-data-from-the-german-federal-statistical-office-from-2000-to-2014
#5
Franziska Brunner, Thula Koops, Timo O Nieder, Geoffrey M Reed, Peer Briken
BACKGROUND: Patients with the ICD-10 sexual disorders F52, F64, F65, and F66 are treated by a variety of medical disciplines. Until now, there has been a paucity of data regarding which sexual disorders are treated by means of in-patient hospital care and whether changes have occurred over time. OBJECTIVES: The aim of this study is to examine how many patients with sexual disorders that are classified by ICD-10 chapter V (F) as "mental" are treated as in-patients...
July 31, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/28760398/symptomatic-clitoromegaly-case-report-of-a-clitoral-hemangioma
#6
Chandler A Kasuske, Keith A Hansen
BACKGROUND: Clitoromegaly is often a sign of an underlying disorder of sexual development. Isolated clitoromegaly may occur as a result of benign or malignant neoplasm. CASE: A 10-year-old female presented with clitoral swelling and discomfort and was noted to have a 5X2X2 centimeter, tender, cystic mass in the left periclitoral area. Ultrasound confirmed the primarily cystic nature of the lesion. At surgery the mass was carefully excised not damaging the clitoral neurovascular bundle...
July 28, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28759479/bipolar-disorder-and-early-emotional-trauma-a-critical-literature-review-on-indicators-of-prevalence-rates-and-clinical-outcomes
#7
Aline Limiéri Dualibe, Flávia L Osório
OBJECTIVES: We performed a systematic literature review to (1) evaluate the prevalence rates of early emotional trauma (EET) in patients with bipolar disorder (BD) and the impact of these traumas on the development of the disorder, and (2) integrate the findings of our review with those previously reported by Fisher and Hosang, Daruy-Filho and colleagues, and Maniglio. METHODS: The literature search was performed on PubMed, SciELO, and PsycINFO databases using the keywords bipolar disorder, early trauma, physical abuse, emotional abuse, sexual abuse, maltreatment, adversity, and neglect...
July 29, 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/28757810/the-influence-of-women-s-neighborhood-resources-on-perceptions-of-social-disorder
#8
Aubrey L Jackson, Brian Soller, Christopher R Browning
Research links neighborhood social disorder with poorer health. But factors beyond observed disorder may influence perceptions that social disorder is problematic. This study investigates whether women's aggregate socioeconomic resources relative to men's in the broader neighborhood context attenuate the extent to which more prevalent observed social disorder within the immediate residential neighborhood contributes to perceptions of more problematic social disorder. This attenuation likely is pronounced among women, for whom sexual harassment in public spaces is a more salient concern compared to men...
June 2017: City & Community
https://www.readbyqxmd.com/read/28757356/flibanserin-from-bench-to-bedside
#9
REVIEW
Erin M Dooley, Melanie K Miller, Anita H Clayton
INTRODUCTION: The process of approval for flibanserin (trade name Addyi) has been associated with controversy since before its approval on August 18, 2015. This argument centered on challenges to the validity of the diagnosis of hypoactive sexual desire disorder in women and the safety and efficacy of the drug. AIM: To explore the process of Food and Drug Administration (FDA) approval for flibanserin and delve further into the research, concerns, and various roadblocks to its approval...
July 27, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28755207/use-of-prazosin-for-pediatric-ptsd-associated-nightmares-and-sleep-disturbances-a-retrospective-chart-review
#10
Brooks R Keeshin, Qian Ding, Angela P Presson, Steven J Berkowitz, Jeffrey R Strawn
INTRODUCTION: Youth exposed to trauma have an increased risk for developing posttraumatic stress disorder (PTSD) and associated sleep disturbances and nightmares. The alpha-1 antagonist prazosin reduces sleep disturbances and nightmares in adults with PTSD; however, its use in youth with PTSD has not been systematically evaluated. We retrospectively examined the tolerability and clinical outcomes associated with prazosin treatment in youth with PTSD-related nightmares and dysomnias. METHOD: A retrospective chart review identified youth with PTSD (N = 40) treated with prazosin between 2014 and 2016 in a trauma clinic...
July 28, 2017: Neurology and Therapy
https://www.readbyqxmd.com/read/28748307/systematic-review-of-mental-health-disorders-and-intimate-partner-violence-victimisation-among-military-populations
#11
REVIEW
Katherine Sparrow, Jamie Kwan, Louise Howard, Nicola Fear, Deirdre MacManus
PURPOSE: There is growing awareness of the problem of intimate partner violence (IPV) among military populations. IPV victimisation has been shown to be associated with mental disorder. A better understanding of the link between IPV and mental disorder is needed to inform service development to meet the needs of military families. We aimed to systematically review the literature on the association between IPV victimisation and mental health disorders among military personnel. METHODS: Searches of four electronic databases (Embase, Medline, PsycINFO, and Web of Science) were supplemented by reference list screening...
July 26, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28747541/obesity-a-serious-etiologic-factor-for-male-subfertility-in-modern-society
#12
Yue Liu, Zhide Ding
Obesity, defined as excessive accumulation of fat in adipose tissue, is a metabolic disorder resulting from behavioral, environmental and heritable causes. Such malfunction increases the risk of developing hypertension, diabetes, cardiovascular disease, respiratory problems, osteoarthritis and cancer. Meanwhile, the negative impact of obesity on male reproduction is gradually being recognized. According to clinical investigations and animal experiments, obesity is correlated with reductions in sperm concentration and motility, increases in sperm DNA damage and changes in reproductive hormonal levels...
July 26, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28745464/elite-athletes-and-pubertal-delay
#13
Karina Kapczuk
Intensive physical training and participation in competitive sports during childhood and early adolescence may affect athletes' pubertal development. On the other hand, pubertal timing, early or late, may impact on an athlete selection for a particular sport. Genetic predisposition, training load, nutritional status and psychological stress determine athletes' pubertal timing. Athletes that practice esthetic sports, especially gymnasts, are predisposed to a delay in pubertal development. The growing evidence indicates that energy deficiency, not a systemic training per se, plays a crucial role in the pathogenesis of functional hypothalamic hypogonadism in female athletes...
October 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28743237/gender-differences-in-characteristics-of-physical-and-sexual-victimization-in-patients-with-dual-diagnosis-a-cross-sectional-study
#14
Marleen M de Waal, Jack J M Dekker, Martijn J Kikkert, Maaike D Kleinhesselink, Anna E Goudriaan
BACKGROUND: Patients with substance use disorders and co-occurring mental health disorders are vulnerable to violent victimization. However, no evidence-based interventions are available to reduce patients' vulnerability. An exploration of the characteristics of physical and sexual violence can provide valuable information to support the development of interventions for these patients. This study aimed to examine gender differences in characteristics of violent victimization in patients with dual diagnosis...
July 25, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28741810/gender-differences-in-machine-learning-models-of-trauma-and-suicidal-ideation-in-veterans-of-the-iraq-and-afghanistan-wars
#15
Jaimie L Gradus, Matthew W King, Isaac Galatzer-Levy, Amy E Street
Suicide rates among recent veterans have led to interest in risk identification. Evidence of gender-and trauma-specific predictors of suicidal ideation necessitates the use of advanced computational methods capable of elucidating these important and complex associations. In this study, we used machine learning to examine gender-specific associations between predeployment and military factors, traumatic deployment experiences, and psychopathology and suicidal ideation (SI) in a national sample of veterans deployed during the Iraq and Afghanistan conflicts (n = 2,244)...
August 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28740851/burden-of-misconception-in-sexual-health-care-setting-a-cross-sectional-investigation-among-the-patients-attending-a-psychiatric-sex-clinic-of-bangladesh
#16
S M Yasir Arafat, Srijony Ahmed
BACKGROUND: Bangladesh is a country in South Asia with about 160 million people and achieved health related Millennium Development Goals (MDG) significantly. But sexual health is still an untapped issue with predominant myths and misconception. OBJECTIVE: We aimed to look into the proportions of patients attending sexual health care services due to misconceptions. METHODS: The descriptive, cross-sectional study was conducted among 110 patients attending Psychiatric Sex Clinic (PSC) of Bangabandhu Sheikh Mujib Medical University...
2017: Psychiatry Journal
https://www.readbyqxmd.com/read/28715127/increased-aggression-and-lack-of-maternal-behavior-in-dio3-deficient-mice-are-associated-with-abnormalities-in-oxytocin-and-vasopressin-systems
#17
J Patrizia Stohn, M Elena Martinez, Maryam Zafer, Daniela López-Espíndola, Lauren M Keyes, Arturo Hernandez
Thyroid hormones regulate many aspects of brain development and function, and alterations in the levels of thyroid hormone action lead to abnormal anxiety- and depression-like behaviors. A complement of factors in the brain function independently of circulating levels of hormone to strictly controlled local thyroid hormone signaling. A critical factor is the type 3 deiodinase (DIO3), which is located in neurons and protects the brain from excessive thyroid hormone. Here we examined whether a local increase in brain thyroid hormone action secondary to DIO3 deficiency is of consequence for social behaviors...
July 17, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28714321/zoophilia-in-an-adolescent-with-high-functioning-autism-from-sri-lanka
#18
Miyuru Chandradasa, Layani Champika
OBJECTIVE: Zoophilia is a rare paraphilic disorder with intense sexual urges involving animals. Autism is characterised by impairments in social communication and repetitive, restricted behaviours (RRB). Reported cases of zoophilia are limited worldwide, and zoophilia in autism is rarer. METHOD: This is a case report describing this unique and relatively unrecognised association in a male adolescent from Sri Lanka. RESULTS: A 17-year-old boy diagnosed with autism has average intelligence and academic capabilities...
July 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28711745/child-maltreatment-and-age-of-alcohol-and-marijuana-initiation-in-high-risk-youth
#19
Laura J Proctor, Terri Lewis, Scott Roesch, Richard Thompson, Alan J Litrownik, Diana English, Amelia M Arria, Patricia Isbell, Howard Dubowitz
INTRODUCTION: Youth with a history of child maltreatment use substances and develop substance use disorders at rates above national averages. Thus far, no research has examined pathways from maltreatment to age of substance use initiation for maltreated youth. We examined the longitudinal impact of maltreatment in early childhood on age of alcohol and marijuana use initiation, and whether internalizing and externalizing behaviors at age 8 mediates the link between maltreatment and age of substance use initiation...
June 30, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28711608/do-anabolic-androgenic-steroids-have-performance-enhancing-effects-in-female-athletes
#20
REVIEW
Grace Huang, Shehzad Basaria
Doping with anabolic-androgenic steroids (AAS) is common among both male and female athletes and is a growing public health problem. Review of historical data of systematic state-sponsored doping programs implemented by the German Democratic Republic in elite female athletes and from clinical trials of testosterone administration in non-athlete women suggests that AAS have ergogenic effects in women. The use of AAS in female athletes has been associated with adverse effects that include acne, hirsutism, deepening of the voice and menstrual disturbances; life-threatening adverse effects such as cardiac arrhythmias and sudden death have also been reported...
July 12, 2017: Molecular and Cellular Endocrinology
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