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https://www.readbyqxmd.com/read/28343007/bioconcentration-and-multi-biomarkers-of-organic-uv-filters-bm-dbm-and-od-paba-in-crucian-carp
#1
Binni Ma, Guanghua Lu, Jianchao Liu, Zhenhua Yan, Haohan Yang, Ting Pan
Organic UV filters (OUV-Fs) are increasingly used in sunscreens and personal care products. In the present work, the bioconcentration and multi-biomarker effects of butyl methoxydibenzoylmethane (BM-DBM) and ethylhexyl dimethyl p-aminobenzoate (OD-PABA) were investigated in crucian carp (Carassius auratus). The fish were exposed to various concentrations of BM-DBM (3.88, 35.61, 181.85 and 337.15μg/L), OD-PABA (4.66, 53.83, 264.22 and 459.32μg/L) and their mixture (2.31+2.79, 23.69+26.18, 97.37+134.81 and 193...
March 23, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28339343/alterations-in-multiple-lifestyle-factors-in-subjects-with-the-metabolic-syndrome-independently-of-obesity
#2
Vendela Roos, Sölve Elmståhl, Erik Ingelsson, Johan Sundström, Johan Ärnlöv, Lars Lind
BACKGROUND: Many lifestyle factors have been associated with the metabolic syndrome (MetS). However, most of these studies have not considered the potential impact of obesity and have often only investigated one lifestyle factor at the time. We aimed to investigate the interplay between body mass index (BMI) and MetS with respect to multiple lifestyle factors. METHODS: BMI and MetS [National Cholesterol Education Program (NCEP)/Adult Treatment Panel III criteria] were assessed in a sample of 18,880 subjects aged 45-75 years from the population-based EpiHealth study...
April 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28338698/thermally-driven-bubble-evolution-at-a-heater-wire-in-water-characterized-by-high-speed-transmission-electron-microscopy
#3
J R Vance, S J Dillon
This work investigates the early stage evolution of thermally nucleated microbubbles in water using in situ high-speed, 400 fps, transmission electron microscopy. A Pt wire Joule heater induced bubble nucleation and growth from air-saturated water at different levels of power. For all powers below Pt breakdown, the dissolved gas initiates bubble nucleation at the concave surface defects adjacent to the area of highest temperature. A combination of interfacial forces and stress relaxation drive rapid migration of the bubbles away from the nucleation site...
March 24, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28338242/what-can-community-pharmacy-learn-from-the-experiences-of-transition-to-practice-for-novice-doctors-and-nurses-a-narrative-review
#4
REVIEW
Esnath Magola, Sarah C Willis, Ellen I Schafheutle
OBJECTIVES: In the absence of literature reporting the transition experiences of novice community pharmacists, peer-reviewed evidence on the transition experiences of novice doctors and nurses was identified and reviewed. Specific objectives included identifying the challenges to transition and their perceived impact, before considering the implications for novice community pharmacists. METHODS: The electronic databases MEDLINE, EMBASE, CINAHL, PsycINFO and ScienceDirect were searched for full peer-reviewed original research papers published 1990-March 2015, reporting the transition experiences of novice doctors and nurses...
March 24, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28337094/prevalence-and-correlates-of-job-stress-among-junior-doctors-in-the-university-college-hospital-ibadan
#5
J O Adeolu, O B Yussuf, O A Popoola
BACKGROUND: Doctors respond differently to their complex work environment, some find it stimulating while others find it stressful. This study aimed to assess the prevalence and correlates of stress among junior doctors in a teaching hospital in Southwest Nigeria. METHOD: A descriptive cross sectional survey of all junior doctors employed at the University College Hospital, Ibadan was carried out. Information was collected with a structured pretested questionnaire from 253 doctors...
December 2016: Annals of Ibadan Postgraduate Medicine
https://www.readbyqxmd.com/read/28336096/multigenerational-effects-of-two-glucocorticoids-prednisolone-and-dexamethasone-on-life-history-parameters-of-crustacean-ceriodaphnia-dubia-cladocera
#6
Navdeep Bal, Anupama Kumar, Jun Du, Dayanthi Nugegoda
Synthetic glucocorticoids (GCs) such as dexamethasone (DEX) and prednisolone (PDS) have been used since the 1940s to cure inflammatory and auto-immune disorders. Their use has been linked to a host of deleterious effects in aquatic ecosystems such as osteoporosis in vertebrates, developmental impairments in molluscs and reduced fecundity and growth in cladocerans. Apart from these handful of studies, the effects of GCs on aquatic biota are largely unknown. The present study is a first of its kind aiming to assess the multi-generational exposure effects of DEX and PDS on the life history parameters of Ceriodaphnia dubia (C...
March 20, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28334672/effects-of-4-mbc-and-triclosan-in-embryos-of-the-frog-pelophylax-perezi
#7
Diana Martins, Marta S Monteiro, Amadeu M V M Soares, Carla Quintaneiro
The widespread and increasing use of personal care products (PCPs) have led to environmental contamination by substances included in these products. These substances have been detected in aquatic compartments and shown to cause adverse effects on non-target aquatic organisms. In this work toxicity of the antimicrobial triclosan (TCS) and of the UV-filter 3-(4-methylbenzylidene) camphor (4-MBC) was assessed in the embryos of Perez' frog Pelophylax perezi. Lethal and sub-lethal parameters were evaluated in embryos in Gosner stage 8-9 exposed to 0...
March 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28330985/a-mechanically-coupled-reaction-diffusion-model-that-incorporates-intra-tumoural-heterogeneity-to-predict-in-vivo-glioma-growth
#8
David A Hormuth, Jared A Weis, Stephanie L Barnes, Michael I Miga, Erin C Rericha, Vito Quaranta, Thomas E Yankeelov
While gliomas have been extensively modelled with a reaction-diffusion (RD) type equation it is most likely an oversimplification. In this study, three mathematical models of glioma growth are developed and systematically investigated to establish a framework for accurate prediction of changes in tumour volume as well as intra-tumoural heterogeneity. Tumour cell movement was described by coupling movement to tissue stress, leading to a mechanically coupled (MC) RD model. Intra-tumour heterogeneity was described by including a voxel-specific carrying capacity (CC) to the RD model...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28330831/the-efficacy-of-internet-based-mindfulness-training-and-cognitive-behavioral-training-with-telephone-support-in-the-enhancement-of-mental-health-among-college-students-and-young-working-adults-randomized-controlled-trial
#9
Winnie Ws Mak, Floria Hn Chio, Amy Ty Chan, Wacy Ws Lui, Ellery Ky Wu
BACKGROUND: College students and working adults are particularly vulnerable to stress and other mental health problems, and mental health promotion and prevention are needed to promote their mental health. In recent decades, mindfulness-based training has demonstrated to be efficacious in treating physical and psychological conditions. OBJECTIVE: The aim of our study was to examine the efficacy of an Internet-based mindfulness training program (iMIND) in comparison with the well-established Internet-based cognitive-behavioral training program (iCBT) in promoting mental health among college students and young working adults...
March 22, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28329406/treating-veterans-with-ptsd-and-borderline-personality-symptoms-in-a-12-week-intensive-outpatient-setting-findings-from-a-pilot-program
#10
Laura Meyers, Emily K Voller, Ethan B McCallum, Paul Thuras, Sandra Shallcross, Tina Velasquez, Laura Meis
Rates of comorbidity between borderline personality disorder and posttraumatic stress disorder (PTSD) are high in veteran populations, and clinicians are hesitant to treat PTSD given high rates of suicidality. Given promising early work integrating dialectical behavior therapy (DBT) and prolonged exposure (PE) therapy, we created a 12-week intensive outpatient program combining these two treatments. PE and DBT were provided concurrently to 33 veterans with PTSD symptoms and BPD symptoms at a large, midwestern Veteran Affairs medical center...
March 22, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28328988/molecular-mechanisms-of-thermal-resistance-of-the-insect-trypanosomatid-crithidia-thermophila
#11
Aygul Ishemgulova, Anzhelika Butenko, Lucie Kortišová, Carolina Boucinha, Anastasiia Grybchuk-Ieremenko, Karina A Morelli, Martina Tesařová, Natalya Kraeva, Danyil Grybchuk, Tomáš Pánek, Pavel Flegontov, Julius Lukeš, Jan Votýpka, Márcio Galvão Pavan, Fred R Opperdoes, Viktoria Spodareva, Claudia M d'Avila-Levy, Alexei Yu Kostygov, Vyacheslav Yurchenko
In the present work, we investigated molecular mechanisms governing thermal resistance of a monoxenous trypanosomatid Crithidia luciliae thermophila, which we reclassified as a separate species C. thermophila. We analyzed morphology, growth kinetics, and transcriptomic profiles of flagellates cultivated at low (23°C) and elevated (34°C) temperature. When maintained at high temperature, they grew significantly faster, became shorter, with genes involved in sugar metabolism and mitochondrial stress protection significantly upregulated...
2017: PloS One
https://www.readbyqxmd.com/read/28327616/genetic-control-of-autophagy-underlies-pathogenesis-of-inflammatory-bowel-disease
#12
REVIEW
K G Lassen, R J Xavier
Autophagy contributes to cellular homeostasis in the face of nutrient deprivation and other cellular stresses. Cell type-specific functions for autophagy are critical in maintaining homeostasis at both the tissue level and at the whole-organism level. Recent work has highlighted the ways in which human genetic variants modulate autophagy to alter epithelial and immune responses in inflammatory bowel disease.Mucosal Immunology advance online publication 22 March 2017. doi:10.1038/mi.2017.18.
March 22, 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/28327057/production-of-lipid-containing-microalgal-biomass-and-simultaneous-removal-of-nitrate-and-phosphate-from-synthetic-wastewater
#13
M S V Prasad, A K Varma, P Kumari, P Mondal
The major concerns of the modern society such as increasing population, climate change and economic development are imposing continuous stress on water and energy resources. The present work deals with the cultivation of green algae Desmodesmus abundans for optimum biomass productivity and lipid content as well as simultaneous removal of nitrate and phosphate from synthetic wastewater. The algal biomass is characterized by ultimate analysis, scanning electron microscopic (SEM) analysis and thermogravimetric (TG) analysis...
March 22, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28326315/genomewide-expression-and-functional-interactions-of-genes-under-drought-stress-in-maize
#14
Nepolean Thirunavukkarasu, Rinku Sharma, Nidhi Singh, Kaliyugam Shiriga, Sweta Mohan, Swati Mittal, Shikha Mittal, Mallana Gowdra Mallikarjuna, Atmakuri Ramakrishna Rao, Prasanta Kumar Dash, Firoz Hossain, Hari Shanker Gupta
A genomewide transcriptome assay of two subtropical genotypes of maize was used to observe the expression of genes at seedling stage of drought stress. The number of genes expressed differentially was greater in HKI1532 (a drought tolerant genotype) than in PC3 (a drought sensitive genotype), indicating primary differences at the transcriptional level in stress tolerance. The global coexpression networks of the two genotypes differed significantly with respect to the number of modules and the coexpression pattern within the modules...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28326162/trauma-informed-care-for-children-in-the-ambulance-international-survey-among-pre-hospital-providers
#15
Eva Alisic, Mark P Tyler, Melita J Giummarra, Rahim Kassam-Adams, Juul Gouweloos, Markus A Landolt, Nancy Kassam-Adams
Background: Pre-hospital providers, such as paramedics and emergency medical technicians, are in a position to provide key emotional support to injured children and their families. Objective: Our goal was to examine (a) pre-hospital providers' knowledge of traumatic stress in children, attitudes towards psychosocial aspects of care, and confidence in providing psychosocial care, (b) variations in knowledge, attitudes, and confidence according to demographic and professional characteristics, and (c) training preferences of pre-hospital providers regarding psychosocial care to support paediatric patients and their families...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28326094/selection-and-validation-of-reference-genes-for-accurate-rt-qpcr-data-normalization-in-coffea-spp-under-a-climate-changes-context-of-interacting-elevated-co2-and-temperature
#16
Madlles Q Martins, Ana S Fortunato, Weverton P Rodrigues, Fábio L Partelli, Eliemar Campostrini, Fernando C Lidon, Fábio M DaMatta, José C Ramalho, Ana I Ribeiro-Barros
World coffee production has faced increasing challenges associated with ongoing climatic changes. Several studies, which have been almost exclusively based on temperature increase, have predicted extensive reductions (higher than half by 2,050) of actual coffee cropped areas. However, recent studies showed that elevated [CO2] can strongly mitigate the negative impacts of heat stress at the physiological and biochemical levels in coffee leaves. In addition, it has also been shown that coffee genotypes can successfully cope with temperatures above what has been traditionally accepted...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28325895/simulation-assisted-design-of-microfluidic-sample-traps-for-optimal-trapping-and-culture-of-non-adherent-single-cells-tissues-and-spheroids
#17
Nassim Rousset, Frédéric Monet, Thomas Gervais
This work focuses on modelling design and operation of "microfluidic sample traps" (MSTs). MSTs regroup a widely used class of microdevices that incorporate wells, recesses or chambers adjacent to a channel to individually trap, culture and/or release submicroliter 3D tissue samples ranging from simple cell aggregates and spheroids, to ex vivo tissue samples and other submillimetre-scale tissue models. Numerous MST designs employing various trapping mechanisms have been proposed in the literature, spurring the development of 3D tissue models for drug discovery and personalized medicine...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28322912/maternal-prenatal-cortisol-predicts-infant-negative-emotionality-in-a-sex-dependent-manner
#18
Elizabeth C Braithwaite, Andrew Pickles, Helen Sharp, Vivette Glover, Kieran J O'Donnell, Jonathan Hill
OBJECTIVE: Prenatal stress influences fetal developmental trajectories, which may implicate glucocorticoid mechanisms. There is also emerging evidence that effects of prenatal stress on offspring development are sex-dependent. However, little is known about the prospective relationship between maternal prenatal cortisol levels and infant behaviour, and whether it may be different in male and female infants. We sought to address this question using data from a prospective longitudinal cohort, stratified by risk...
March 16, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28322540/a-rapid-recovery-double-crosslinking-hydrogel-with-stable-mechanical-properties-and-high-resilience-triggered-by-visible-light
#19
Longxiang Zhu, Jianhui Qiu, Eiichi Sakai, Kazushi Ito
The designed tough hydrogels, depending on energy dissipation mechanism, possess excellent biocompatibility, stimuli-responsiveness and outstanding mechanical properties. However, the application of hydrogels are greatly limited in actuators and sensors for the lack of instantaneous recovery and resilience. In this work, we synthesized a double crosslinking polyacrylic acid hydrogel via a simple, one-pot, visible-light-trigger polymerization, where carboxymethyl cellulose as initiator and the first cross-linker, N,N'-methylene bisacrylamide (MBA) as the second cross-linker...
March 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28322176/gender-regimes-in-ontario-nursing-homes-organization-daily-work-and-bodies
#20
Palle Storm, Susan Braedley, Sally Chivers
Today more men work in the long-term care sector, but men are still in the minority. Little is known about men's experiences in care work, and the dilemmas and opportunities they face because of their gender. This article focuses on men care workers' integration into the organization and flow of nursing home work as perceived by these workers and staff members. Using a rapid ethnography method in two Ontario nursing homes, we found work organization affected interpretations of gender and race, and that workers' scope for discretion affected the integration and acceptance of men as care workers...
March 21, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
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