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https://www.readbyqxmd.com/read/28434435/association-between-burnout-and-cortisol-secretion-perceived-stress-and-psychopathology-in-palliative-care-unit-health-professionals
#1
José Carlos Fernández-Sánchez, José Manuel Pérez-Mármol, Antonia Blásquez, Ana María Santos-Ruiz, María Isabel Peralta-Ramírez
OBJECTIVE: A high incidence of burnout has been reported in health professionals working in palliative care units. Our present study aims to determine whether there are differences in the secretion of salivary cortisol between palliative care unit health professionals with and without burnout, and to elucidate whether there is a relationship between burnout syndrome and perceived stress and psychopathological status in this population. METHOD: A total of 69 health professionals who met the inclusion criteria participated in our study, including physicians, nurses, and nursing assistants...
April 24, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28434182/recent-trends-in-alcohol-and-other-drug-use-among-police-detainees-in-new-zealand-2010-2015
#2
Chris Wilkins, Jitesh Prasad, Karl Parker, Marta Rychert, Helen Moewaka Barnes
BACKGROUND: New Zealand has unusual patterns of recreational substance use by international standards including low levels of cocaine and heroin use, and high methamphetamine use. AIMS: This paper examines recent trends in alcohol and other drug use among police detainees in New Zealand over the past six years. METHOD: The paper utilises data from the New Zealand Arrestee Drug Use Monitoring (NZ-ADUM) study. NZ-ADUM interviewed approximately 800 police detainees each year at four central city police watch houses (i...
April 23, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28433950/an-electrocortical-investigation-of-emotional-face-processing-in-military-related-posttraumatic-stress-disorder
#3
Julia A DiGangi, Katie L Burkhouse, Darrin M Aase, Joseph M Babione, Christopher Schroth, Amy E Kennedy, Justin E Greenstein, Eric Proescher, K Luan Phan
PTSD is a disorder of emotion dysregulation. Although much work has intended to elucidate the neural underpinnings of the disorder, much remains unknown about the neurobiological substrates of emotion dysregulation in PTSD. In order to assess the relationship between a neural measure of attention to emotion (i.e. the late positive potential; LPP) and PTSD symptoms, EEG was recorded and examined as a potential predictor of military-related PTSD symptoms in a sample of 73 OEF/OIF/OND veterans. Results revealed that higher PTSD symptoms were related to an attenuated LPP response to angry facial expressions...
March 20, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28433592/toxicity-assessment-of-multi-walled-carbon-nanotubes-on-cucurbita-pepo-l-under-well-watered-and-water-stressed-conditions
#4
Mehrnaz Hatami
The rapid increase in the production and application of various types of nanomaterials increases the possibility of their presence in total environment, which subsequently raises concerns about their potential threats to the first trophic level of organisms, specifically under varying environmental constraints. In this work, seeds of Cucurbita pepo L. were cultured in MS basal medium exposed to multi-walled carbon nanotubes (MWCNTs) at different concentrations (0, 125, 250, 500 and 1000μgmL(-1)) under two levels of water potential, well-watered (0MPa) and water stress (-1...
April 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28432967/friendliness-functionality-and-freedom-design-characteristics-that-support-midwifery-practice-in-the-hospital-setting
#5
Athena Hammond, Caroline S E Homer, Maralyn Foureur
OBJECTIVE: to identify and describe the design characteristics of hospital birth rooms that support midwives and their practice. DESIGN: this study used a qualitative exploratory descriptive methodology underpinned by the theoretical approach of critical realism. Data was collected through 21 in-depth, face-to-face photo-elicitation interviews and a thematic analysis guided by study objectives and the aims of exploratory research was undertaken. SETTING: the study was set at a recently renovated tertiary hospital in a large Australian city...
April 4, 2017: Midwifery
https://www.readbyqxmd.com/read/28432963/health-hazards-of-child-labor-in-the-leather-products-and-surgical-instrument-manufacturing-industries-of-sialkot-pakistan
#6
Muhammad Junaid, Riffat Naseem Malik, De-Sheng Pei
Child labor is a major challenge in the developing countries and comprehensive health hazard identification studies on this issue are still lacking. Therefore, the current study is an effort to highlight the health concerns of child labor exposed in the key small scale industries of Sialkot, Pakistan. Our findings revealed jolting levels of heavy metals in the urine, blood, serum, saliva, and hair samples collected from the exposed children. For example, in the urine samples, Cd, Cr, Ni, and Pb were measured at the respective concentrations of 39...
April 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28432422/country-differences-of-psychosocial-working-conditions-in-europe-the-role-of-health-and-safety-management-practices
#7
Thorsten Lunau, Nico Dragano, Johannes Siegrist, Morten Wahrendorf
BACKGROUND: In times of demographic change, maintaining health and employability of older employees is important. In this context, studies show that stressful working conditions differ by countries. Yet, it is unclear if specific national management practices to deal with these conditions contribute towards explaining country differences. METHODS: This study combines two different data sources. The first one provides detailed information on psychosocial working conditions in 17 European countries, based on 12,284 employees from the Survey of Health, Ageing and Retirement in Europe (SHARE) and the English Longitudinal Study of Ageing (ELSA)...
April 21, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28432307/arsenic-metabolism-in-high-altitude-modern-stromatolites-revealed-by-metagenomic-analysis
#8
Daniel Kurth, Ariel Amadio, Omar F Ordoñez, Virginia H Albarracín, Wolfgang Gärtner, María E Farías
Modern stromatolites thrive only in selected locations in the world. Socompa Lake, located in the Andean plateau at 3570 masl, is one of the numerous extreme Andean microbial ecosystems described over recent years. Extreme environmental conditions include hypersalinity, high UV incidence, and high arsenic content, among others. After Socompa's stromatolite microbial communities were analysed by metagenomic DNA sequencing, taxonomic classification showed dominance of Proteobacteria, Bacteroidetes and Firmicutes, and a remarkably high number of unclassified sequences...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28431686/adm-guidance-ceramics-all-ceramic-multilayer-interfaces-in-dentistry
#9
Ulrich Lohbauer, Susanne S Scherrer, Alvaro Della Bona, Michael Tholey, Richard van Noort, Alessandro Vichi, J Robert Kelly, Paulo F Cesar
This guidance document describes the specific issues involved in dental multilayer ceramic systems. The material interactions with regard to specific thermal and mechanical properties are reviewed and the characteristics of dental tooth-shaped processing parameters (sintering, geometry, thickness ratio, etc.) are discussed. Several techniques for the measurement of bond quality and residual stresses are presented with a detailed discussion of advantages and disadvantages. In essence no single technique is able to describe adequately the all-ceramic interface...
April 18, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28429767/love-laughs-at-locksmiths-ubiquitylation-of-p62-sequestosome-1-unlocks-its-autophagy-receptor-potential
#10
Owen Conway, Vladimir Kirkin
The multimodular adapter p62/sequestosome-1 plays prominent roles in physiology and disease by mediating cell signaling and cargo degradation. The work by Peng et al. published recently in Cell Research provides mechanistic insights into activation of its autophagy receptor function critical for maintaining cell homeostasis during various forms of stress.
April 21, 2017: Cell Research
https://www.readbyqxmd.com/read/28427320/the-role-of-inelastic-deformations-in-the-mechanical-response-of-endovascular-shape-memory-alloy-devices
#11
Lorenza Petrini, Alessandro Bertini, Francesca Berti, Giancarlo Pennati, Francesco Migliavacca
Nickel-titanium alloys are commonly adopted for producing cardiovascular minimally invasive devices such as self-expandable stents, aortic valves and stent-grafts. These devices are subjected to cyclic loads (due to blood pulsatility, leg or heart movements), that can induce fatigue fracture, and may also be subjected to very large deformations (due to crimping procedure, a tortuous physiological path or overloads), that can induce material yield. Recently, the authors developed a new constitutive model that considers inelastic strains due to not-completed reverse phase transformation (not all the stress-induced martensite turns back to austenite) or/and plasticity and their accumulation during cyclic loads...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28427317/nonlinear-homogenisation-of-trabecular-bone-effect-of-solid-phase-constitutive-model
#12
Francesc Levrero-Florencio, Krishnagoud Manda, Lee Margetts, Pankaj Pankaj
Micro-finite element models have been extensively employed to evaluate the elastic properties of trabecular bone and, to a limited extent, its yield behaviour. The macroscopic stiffness tensor and yield surface are of special interest since they are essential in the prediction of bone strength and stability of implants at the whole bone level. While macroscopic elastic properties are now well understood, yield and post-yield properties are not. The aim of this study is to shed some light on what the effect of the solid phase yield criterion is on the macroscopic yield of trabecular bone for samples with different microstructure...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28427315/computational-modeling-of-long-term-effects-of-prophylactic-vertebroplasty-on-bone-adaptation
#13
Sandro D Badilatti, Patrik Christen, Stephen J Ferguson, Ralph Müller
Cement augmentation in vertebrae (vertebroplasty) is usually used to restore mechanical strength after spinal fracture but could also be used as a prophylactic treatment. So far, the mechanical competence has been determined immediately post-treatment, without considering long-term effects of bone adaptation. In this work, we investigated such long-term effects of vertebroplasty on the stiffness of the augmented bone by means of computational simulation of bone adaptation. Using micro-finite element analysis, we determined sites of increased mechanical stress (stress raisers) and stress shielding and, based on the simulations, regions with increased or decreased bone loss due to augmentation...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28426563/routine-inclusion-of-long-term-functional-and-patient-reported-outcomes-pros-into-trauma-registries-the-forte-project
#14
Arturo J Rios-Diaz, Juan P Herrera-Escobar, Elizabeth J Lilley, Jessica R Appelson, Belinda Gabbe, Karen Brasel, Terri deRoon-Cassini, Eric B Schneider, George Kasotakis, Haytham Kaafarani, George Velmahos, Ali Salim, Adil H Haider
BACKGROUND: The National Academies of Sciences, Engineering, and Medicine (formerly the Institute of Medicine) recently recommended inclusion of post-discharge health-related quality of life (HRQoL) and patient-reported outcomes (PROs) metrics to benchmark the quality of trauma care. Currently, these measures are not routinely collected at most trauma centers. We sought to determine the feasibility and value of adding such long-term outcome measures to trauma registries. METHODS: As part of the Functional Outcomes and Recovery after Trauma Emergencies (FORTE) project we included patients with an ISS ≥9, admitted to the Brigham and Women's Hospital in Boston, MA who were identified retrospectively using the institutional trauma registry and contacted 6 or 12-months post-injury to participate in a telephone survey evaluating: HRQoL (Short Form-12 [SF-12]), PROs (Trauma Quality of Life [T-QoL]), post-traumatic stress disorder (PTSD), return to work, residential status, and healthcare utilization...
April 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28426518/pathophysiologic-insight-into-mesoamerican-nephropathy
#15
Magdalena Madero, Fernando E García-Arroyo, Laura-Gabriela Sánchez-Lozada
PURPOSE OF REVIEW: Mesoamerican nephropathy (MeN) is an emerging pathophysiological entity of Chronic kidney desease (CKD) not related to traditional risk factors (diabetes and hypertension) that have caused thousands of deaths in Central America, mainly in sugarcane workers. The focus of this review is to discuss the risk factors and probable mechanisms involved in the initiation and progression of this devastating disease. RECENT FINDINGS: Frequent episodes of subclinical Acute kidney injury caused by repetitive heat stress, dehydration, and strenuous work have been regarded as the main risk factors for MeN...
April 19, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28426320/transient-exposure-to-androgens-induces-a-remarkable-self-sustained-quiescent-state-in-dispersed-prostate-cancer-cells
#16
Anh Thu Bui, Meng-Er Huang, Maryline Havard, Fanny Laurent-Tchenio, François Dautry, Thierry Tchenio
Cellular quiescence is a reversible cell growth arrest that is often assumed to require a persistence of non-permissive external growth conditions for its maintenance. In this work, we showed that androgen could induce a quiescent state that is self-sustained in a cell-autonomous manner through a "hit and run" mechanism in androgen receptor-expressing prostate cancer cells. This phenomenon required the set-up of a sustained redox imbalance and TGFβ/BMP signaling that were dependent on culturing cells at low density...
April 20, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28426283/identification-of-the-proteome-complement-of-humantlk1-reveals-it-binds-and-phosphorylates-nek1-regulating-its-activity
#17
Vibha Singh, Zachary M Connelly, Xinggui Shen, Arrigo De Benedetti
The Tousled Like kinases (TLKs) are involved in numerous cellular functions, including the DNA Damage Response (DDR), but only a handful of substrates have been identified thus far. Through a novel proteomic screen, we have now identified 165 human proteins interacting with TLK1, and we have focused this work on NEK1 because of its known role in the DDR, upstream of ATR and Chk1. TLK1 and NEK1 were found to interact by coIP, and their binding is strengthened following exposure of cells to H2O2. Following incubation with doxorubicin, TLK1 and NEK1 relocalize with nuclear repair foci along with γH2AX...
April 20, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28425584/changes-in-ciap2-survivin-and-bimel-expression-characterize-the-switch-from-autophagy-to-apoptosis-in-prolonged-starvation
#18
A Hay-Koren, S Bialik, V Levin-Salomon, A Kimchi
BACKGROUND: Autophagy is a catabolic process involving the engulfment of cytoplasmic content within autophagosomes followed by their delivery to lysosomes. This process is a survival mechanism, enabling cells to cope with nutrient deprivation by degradation and recycling of macromolecules. Yet during continued stress such as prolonged starvation, a switch from autophagy to apoptosis is often detected. OBJECTIVE: In this work, we characterized the temporal dynamics of the transition from autophagy towards apoptosis with the aim of elucidating the molecular mechanism regulating the switch from survival autophagy to apoptotic cell death...
May 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28425150/genetic-basis-for-soma-is-present-in-undifferentiated-volvocine-green-algae
#19
Zachariah I Grochau-Wright, Erik R Hanschen, Patrick J Ferris, Takashi Hamaji, Hisayoshi Nozaki, Bradley J S C Olson, Richard E Michod
Somatic cellular differentiation plays a critical role in the transition from unicellular to multicellular life, but the evolution of its genetic basis remains poorly understood. By definition somatic cells do not reproduce to pass on genes and so constitute an extreme form of altruistic behavior. The volvocine green algae provide an excellent model system to study the evolution of multicellularity and somatic differentiation. In Volvox carteri, somatic cell differentiation is controlled by the regA gene, which is part of a tandem duplication of genes known as the reg cluster...
April 20, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28424716/growth-stimulatory-effects-and-genome-wide-transcriptional-changes-produced-by-protein-hydrolysates-in-maize-seedlings
#20
Chiara Santi, Anita Zamboni, Zeno Varanini, Tiziana Pandolfini
Protein hydrolysates are an emerging class of crop management products utilized for improving nutrient assimilation and mitigating crop stress. They generally consist of a mixture of peptides and free amino acids derived from the hydrolysis of plant or animal sources. The present work was aimed at studying the effects and the action mechanisms of a protein hydrolysate derived from animal residues on maize root growth and physiology in comparison with the effects induced by either free amino acids or inorganic N supply...
2017: Frontiers in Plant Science
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