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https://www.readbyqxmd.com/read/28791822/a-coronary-proatherosclerotic-marker-pregnancy-associated-plasma-protein-a-and-its-association-with-coronary-calcium-score-and-carotid-intima-media-thickness
#1
Abdullah Guven, Bora Demircelik, Ozgul Malcok Gurel, Okan Er, Halil Ibrahim Aydin, Alper Bozkurt
BACKGROUND: Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for the greatest number of deaths in westernized societies, with numbers increasing at a marked rate in developing countries. Coronary calcium score (CCS), carotid intima-media thickness (CIMT) and pregnancy-associated plasma protein A (PAPP-A) are predictors for the development of atherosclerosis. OBJECTIVES: This study was aimed to investigate the relationship between CCS, CIMT and PAPP-A for earlier diagnosis of atherosclerosis...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28766361/annals-express-diagnostic-specificity-and-sensitivity-of-pivkaii-gp3-cstb-scca1-and-hgf-for-diagnosis-of-hepatocellular-carcinoma-in-patients-with-alcoholic-liver-cirrhosis
#2
Adriana Unic, Lovorka Derek, Marko Duvnjak, Leonardo Patrlj, Mislav Rakic, Milan Kujundzic, Vesna Renjic, Nikola Stokovic, Petra Dinjar, Anita Jukic, Ivica Grgurevic
INTRODUCTION: Despite of some new treatment possibilities the improvement in survival rate for hepatocellular carcinoma (HCC) patients is still poor due to late diagnosis. The aim of this study was to investigate diagnostic sensitivity and specificity of Protein induced by vitamin K absence or antagonist-II (PIVKAII), Glypican-3 (GP3), Cystatin B (CSTB), Squamous cell carcinoma antigen 1 (SCCA1) and Hepatocyte growth factor (HGF) as potential tumour markers for HCC in patients with alcoholic liver cirrhosis (ALC) using imaging techniques (MSCT and MRI) as reference standards...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28761682/a-comparative-study-of-different-imaging-modalities-for-successful-percutaneous-left-atrial-appendage-closure
#3
Danny Hf Chow, Gintautas Bieliauskas, Fadi J Sawaya, Oscar Millan-Iturbe, Klaus F Kofoed, Lars Søndergaard, Ole De Backer
OBJECTIVES: Accurate sizing of the left atrial appendage (LAA) is essential when performing percutaneous LAA closure. This study aimed to compare different LAA imaging modalities and sizing methods in order to obtain successful LAA closure. BACKGROUND: Percutaneous LAA closure is an increasingly used treatment strategy to prevent stroke in patients with atrial fibrillation. LAA sizing has typically been done by 2D-transoesophageal echocardiography (TEE). METHODS: Patients who had a preprocedural TEE and preprocedural and postprocedural multislice CT (MSCT) were identified...
2017: Open Heart
https://www.readbyqxmd.com/read/28755405/serum-ifn-%C3%AE-predicts-the-therapeutic-effect-of-mesenchymal-stem-cells-transplantation-in-systemic-lupus-erythematosus-patients
#4
Dandan Wang, Shiying Wang, Saisai Huang, Zhuoya Zhang, Xinran Yuan, Xuebing Feng, Liwei Lu, Lingyun Sun
Umbilical cord (UC) derived mesenchymal stem cells (MSCs) show immunoregulatory properties on various immune cells and display therapeutic effects on various autoimmune diseases such as systemic lupus erythematosus (SLE). The aim of this study is to investigate the effect of SLE environment on UC MSCs and to identify the possible serum biomarker to predict the therapeutic effect. UC MSCs were cocultured with peripheral blood mononuclear cells (PBMCs) from active lupus patients and the proliferation, apoptosis and surface markers of UC MSCs were observed...
July 29, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28724445/sustained-benefit-from-combined-plasmapheresis-and-allogeneic-mesenchymal-stem-cells-transplantation-therapy-in-systemic-sclerosis
#5
Huayong Zhang, Jun Liang, Xiaojun Tang, Dandan Wang, Xuebing Feng, Fan Wang, Bingzhu Hua, Hong Wang, Lingyun Sun
BACKGROUND: Systemic sclerosis (SSc) is an autoimmune disease involving the skin and several internal organs. Most therapies available for this disease are symptomatic. Given the difficulty in treating SSc, we conducted this study to investigate the effect of combined plasmapheresis (PE) and allogeneic mesenchymal stem cells transplantation (MSCT) therapy on SSc. METHODS: Fourteen patients underwent three repeated PE treatments with subsequent pulse cyclophosphamide on days 1, 3 and 5...
July 19, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28715364/accuracy-of-multi-slice-spiral-computed-tomography-for-preoperative-tumor-node-metastasis-tnm-staging-of-colorectal-carcinoma
#6
Rong-Jie Bai, Shao-Hua Ren, Hui-Jie Jiang, Jin-Ping Li, Xiao-Cheng Liu, Li-Ming Xue
BACKGROUND With the advances in imaging technologies, multi-slice spiral computed tomography (MSCT) has demonstrated superiority in the diagnosis and staging of colorectal carcinoma. In the current study, preoperative TNM staging of colorectal carcinoma by using MSCT was conducted and compared with the corresponding postoperative pathological examination findings, in order to evaluate the accuracy of preoperative MSCT for TNM staging. MATERIAL AND METHODS Combinations of biphasic or triphasic enhanced-phase MSCT scans were obtained for 76 patients with colorectal carcinoma, and the TNM stage was determined based on imaging reconstruction from various angles and perspectives to display the size, location, and affected range of tumors...
July 17, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28708129/validation-of-a-novel-imaging-approach-using-multi-slice-ct-and-cone-beam-ct-to-follow-up-on-condylar-remodeling-after-bimaxillary-surgery
#7
Laura Ferreira Pinheiro Nicolielo, Jeroen Van Dessel, Eman Shaheen, Carolina Letelier, Marina Codari, Constantinus Politis, Ivo Lambrichts, Reinhilde Jacobs
The main goal of this study was to introduce a novel three-dimensional procedure to objectively quantify both inner and outer condylar remodelling on preoperative multi-slice computed tomography (MSCT) and postoperative cone-beam computed tomography (CBCT) images. Second, the reliability and accuracy of this condylar volume quantification method was assessed. The mandibles of 20 patients (11 female and 9 male) who underwent bimaxillary surgery were semi-automatically extracted from MSCT/CBCT scans and rendered in 3D...
July 14, 2017: International Journal of Oral Science
https://www.readbyqxmd.com/read/28697191/an-innovative-method-for-precise-lymph-node-detection-before-surgical-treatment-in-breast-cancer
#8
Milovan Matovic, Dalibor Nikolic, Nenad Filipovic, Dongfang Chen, Marija Jeremic, Slobodan M Jankovic, Srdjan Ninkovic, Aleksandar Cvetkovic, Marina Vlajkovic, Ana Rankovic
OBJECTIVE: To describe a new method of 3D interactive modeling which integrates images obtained by separate SPET and multi slice computed tomography (MSCT) modalities using an original software in order to better localize SNL in BC patients. SUBJECTS AND METHODS: We used technetium-99m-colloid rhenium sulphate for identifying SNL in seven patients with BC. Markers were made of lead pearls wrapped with cotton wool soaked in (99m)Tc-pertechnetate and placed on the skin of the patients forming of a triangle...
May 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28686736/higher-mineralized-bone-volume-is-associated-with-a-lower-plain-x-ray-vascular-calcification-score-in-hemodialysis-patients
#9
Teresa Adragao, Anibal Ferreira, Joao M Frazao, Ana Luisa Papoila, Iola Pinto, Marie-Claude Monier-Faugere, Hartmut H Malluche
BACKGROUND AND OBJECTIVES: In dialysis patients, there is an increasing evidence that altered bone metabolism is associated with cardiovascular calcifications. The main objective of this study was to analyse, in hemodialysis patients, the relationships between bone turnover, mineralization and volume, evaluated in bone biopsies, with a plain X-ray vascular calcification score. DESIGN, SETTING, PARTICIPANTS AND MEASUREMENTS: In a cross-sectional study, bone biopsies and evaluation of vascular calcifications were performed in fifty hemodialysis patients...
2017: PloS One
https://www.readbyqxmd.com/read/28671764/the-evaluation-of-the-non-invasive-msct-based-indices-for-the-diagnosis-and-prognosis-prediction-of-liver-cirrhosis
#10
Ling-Mei Feng, Shu-Juan Lei, Xin Zeng, Pei-Qin Wang, Ru-Tan Chen, Jian Wang, Xia Sheng, Pei-Mei Shi, Zong-Li Yuan, Wei-Fen Xie
PURPOSE: It is necessary to develop feasible and reliable non-invasive methods to determine liver function and predict complications in patients with liver cirrhosis. The aim of this study was to determine the value of CT-based easily available parameters in evaluating the severity of cirrhosis and predicting complications in Chinese cirrhotic patients. METHODS: CT-based morphological indices were determined in 167 cirrhotic patients and 244 healthy volunteers. The correlation of morphological indices with the Child-Pugh score/grade and complication of cirrhosis was analysed by Spearman correlation analysis...
July 3, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28651263/quality-and-dose-optimized-ct-trauma-protocol-recommendation-from-a-university-level-i-trauma-center
#11
Johannes Kahn, David Kaul, Georg Böning, Roman Rotzinger, Patrick Freyhardt, Philipp Schwabe, Martin H Maurer, Diane Miriam Renz, Florian Streitparth
Purpose As a supra-regional level-I trauma center, we evaluated computed tomography (CT) acquisitions of polytraumatized patients for quality and dose optimization purposes. Adapted statistical iterative reconstruction [(AS)IR] levels, tube voltage reduction as well as a split-bolus contrast agent (CA) protocol were applied. Materials and Methods 61 patients were split into 3 different groups that differed with respect to tube voltage (120 - 140 kVp) and level of applied ASIR reconstruction (ASIR 20 - 50 %)...
June 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28631915/-multispiral-computer-tomography-in-differential-diagnosis-of-congenital-uretheroidhydronefrosis-in-children
#12
E B Khakkulov, Zh U Khusankhodzhaev
AIM: To identify the characteristic MSCT signs of pediatric ureterohydronephrosis allowing to assess the disease severity and differentiate between its various forms. MATERIAL AND METHODS: Sixty five children with III-IV grade ureterohydronephrosis underwent a comprehensive examination including MSCT urography. The study comprised 40 (61.5%) boys and 25 (38.5%) girls aged 3 months to 14 years (mean age 4.15+/-3.21 years). RESULTS: Obstructive disease was detected in 38 (58...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28629626/left-atrial-accessory-appendages-diverticula-and-left-sided-septal-pouch-in-multi-slice-computed-tomography-association-with-atrial-fibrillation-and-cerebrovascular-accidents
#13
Mateusz K Hołda, Mateusz Koziej, Karolina Wszołek, Wiesław Pawlik, Agata Krawczyk-Ożóg, Danuta Sorysz, Piotr Łoboda, Katarzyna Kuźma, Marcin Kuniewicz, Jacek Lelakowski, Dariusz Dudek, Wiesława Klimek-Piotrowska
BACKGROUND: The aim of this study is to provide a morphometric description of the left-sided septal pouch (LSSP), left atrial accessory appendages, and diverticula using cardiac multi-slice computed tomography (MSCT) and to compare results between patient subgroups. METHODS: Two hundred and ninety four patients (42.9% females) with a mean of 69.4±13.1years of age were investigated using MSCT. The presence of the LSSP, left atrial accessory appendages, and diverticula was evaluated...
June 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28629625/what-exactly-regression-of-atherosclerosis-or-foreign-body-reaction-with-hyaline-arteriosclerosis-drives-transient-scaffolding-of-coronary-arteries-a-pooled-analysis-of-observational-absorb-studies-with-a-serial-multimodality-imaging-substudy-of-absorb-cohort
#14
Alexander N Kharlamov, John A Feinstein, John A Cramer, John A Boothroyd
OBJECTIVES: We aimed to estimate the trends of the artery remodeling after transient scaffolding. BACKGROUND: At least 2.62% reduction of the per cent atheroma volume (PAV) or plaque burden (PB) performed in ABSORB B trial at 60months. METHODS: The detailed multiple serial imaging evaluation was performed by intravascular ultrasound (IVUS) in comparison with quantitative coronary angiography (QCA), multislice CT (MSCT) and optical coherence tomography (OCT) thru 24months in the ABSORB cohort B1 trial (n=45) with the pooled analysis in ABSORB A and B trials (n=131)...
June 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28606882/the-effect-of-coronary-bifurcation-and-blood-flow-modelling-in-prediction-of-atherosclerotic-plaque-development-a-serial-computed-tomographic-coronary-angiographic-study
#15
Antonis Sakellarios, Christos V Bourantas, Stella-Lida Papadopoulou, Pieter H Kitslaar, Chrysafios Girasis, Gregg W Stone, Johan H C Reiber, Lampros K Michalis, Patrick W Serruys, Pim J de Feyter, Hector M Garcia-Garcia, Dimitrios I Fotiadis
AIMS: Examine the effect of the daughter branches to the haemodynamics and the potential prediction of atherosclerotic plaque development as well as the best flow division model for accurate blood flow modelling. METHODS AND RESULTS: In this study, we analysed computed tomographic coronary angiography retrospective data portraying 17 coronary artery bifurcations in 15 patients recruited in the PROSPECT MSCT study. The baseline and three year follow-up imaging data were used to reconstruct coronary artery anatomy and in the baseline models blood flow simulations was performed using three flow division approaches: stress-free, Murray's law and Doriot's law...
June 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28603099/using-receiver-operating-characteristic-curves-to-evaluate-the-diagnostic-value-of-the-combination-of-multislice-spiral-ct-and-alpha-fetoprotein-levels-for-small-hepatocellular-carcinoma-in-cirrhotic-patients
#16
Guang-Sheng Jia, Guang-Long Feng, Jin-Ping Li, Hai-Long Xu, Hui Wang, Yi-Peng Cheng, Lin-Lin Yan, Hui-Jie Jiang
BACKGROUND: The various combination of multiphase enhancement multislice spiral CT (MSCT) makes the diagnosis of a small hepatocellular carcinoma (sHCC) on the background of liver cirrhosis possible. This study was to explore whether the combination of MSCT enhancement scan and alpha-fetoprotein (AFP) level could increase the diagnostic efficiency for sHCC. METHODS: This study included 35 sHCC patients and 52 cirrhotic patients without image evidence of HCC as a control group...
June 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28594811/-successful-two-stage-surgical-treatment-of-a-thoracoabdominal-aortic-aneurysm-a-case-report
#17
V V Shlomin, D A Zverev, E D Zvereva, P D Puzdriak, P B Bondarenko, M L Gordeev
Presented herein is a clinical case report regarding hybrid or two-stage surgical treatment of a Crawford type II thoracoabdominal aortic aneurysm in an 87-year-old woman. For the first stage operation we performed open resection of the abdominal aortic aneurysm with aortofemoral bifurcation prosthetic repair and debranching of visceral and renal arteries. Several months thereafter, the second stage operation was performed, consisting in transcatheter exclusion of the thoracoabdominal aortic aneurysm with the help of two stent grafts...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28594796/hybrid-surgery-in-chronic-thoracoabdominal-aortic-dissection
#18
A M Cherniavskiĭ, D A Sirota, T Caus, D S Khvan, S A Al'sov, M M Liashenko
The authors describe and analyse their experience gained in performing prosthetic repair of the thoracoabdominal portion of the aorta, combined with open aortic stenting using the Djumbodis uncovered metal stent. Over the period from 2013 to 2015 we performed a total of 16 hybrid interventions. All patients were found to have type B aortic dissection, with their false and true lumens patent. All patients underwent reconstruction of the thoracoabdominal aorta combined with open implantation of the Djumbodis uncovered metal stent into the area of lower thoracic and visceral arteries...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28593884/transposition-of-subclavian-artery-is-it-the-appropriate-choice
#19
Nikola Lazovski, Sasko Jovev, Dusan Babic, Srdjan Babic, Omer Dzemali
INTRODUCTION: To present patients with symptomatic subclavian artery disease and treatment possibility. CASE REPORT: A 53-year-old female was admitted with vertigo and left arm claudication. Duplex-scan and MSCT arteriography verified subclavian artery occlusion. After the endovascular treatment failure, the patient was switched to surgical treatment - subclavian artery transposition. After the successful surgical treatment, the patient was discharged on the second postoperative day...
March 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28587323/clinical-relevance-of-gemstone-spectral-ct-in-the-diagnosis-of-carotid-atherosclerosis
#20
Jing-Jian Wang, Shu-Jie Fan, Long-Long Wang, Yan-Zhong Gao, Xiao-Juan Liu
A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional multi-slice CT (MSCT). In total, 200 patients were enrolled and divided into the experimental group (n=100), which underwent GSCT, and the control group (n=100), which underwent MSCT. All the cases were followed up to observe disease outcomes in patients with different atherosclerotic plaque types, and adverse events in carotid artery stenosis or cerebral infarction were recorded...
June 2017: Experimental and Therapeutic Medicine
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