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https://www.readbyqxmd.com/read/28150295/impact-of-corevalve-size-selection-based-on-multi-slice-computer-tomography-on-paravalvular-leak-after-transcatheter-aortic-valve-implantation
#1
Piotr Chodór, Krzysztof Wilczek, Roman Przybylski, Jan Głowacki, Tomasz Kukulski, Witold Streb, Tomasz Niklewski, Grzegorz Honisz, Przemysław Trzeciak, Tomasz Podolecki, Łukasz Włoch, Marian Zembala, Zbigniew Kalarus
BACKGROUND: Paravalvular leak (PVL) has significant impact on long-term outcomes in patients after transcatheter aortic valve implantation (TAVI). This study sought to determine whether multi-slice computed tomography (MSCT)-guided valve selection reduces PVL after CoreValve implantation. METHODS: The analysis encompassed 69 patients implanted with CoreValve and were divided into two groups. In Group I (30 patients), valve selection was based on standard procedures, in Group II (39 pts), on MSCT measurements...
February 2, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28150269/applications-of-digital-technology-for-the-morphological-study-of-c3-c7-vertebral-arch-pedicle-in-children
#2
S Zhang, X Wang, X Ren, Z Li, Y Zhang
BACKGROUND: This study aims to investigate the morphological characteristics and developmental patterns of the vertebral arch pedicle (VAP) in the lower cervical vertebrae of children, and to subsequently help guide the implantation of the pedicle screw. METHODS: The cervical vertebral multi-slice computed tomography (MSCT) data of 60 pediatric patients aged 4 to 12 years were collected and grouped. A reconstructed 3D model measured the following: pedicle width (PW), pedicle height (PH), pedicle osseous channel (POCL), pedicle transverse angle (PTA, namely the E angle), and pedicle sagittal angle (PTA, namely the F angle)...
February 2, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28128540/determinants-of-aortic-regurgitation-after-transcatheter-aortic-valve-implantation-an-observational-study-using-multi-slice-computed-tomography-msct-guided-sizing
#3
Zouhair Rahhab, Nahid El Faquir, Ramón Rodríguez-Olivares, Claire Ren, Nicolas VAN Mieghem, Marcel L Geleijnse, Carl Schultz, Ron VAN Domburg, Peter P DE Jaegere
BACKGROUND: To explore the determinants of aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) using Multi Slice Computed Tomography (MSCT) instead of echocardiography-guided sizing. METHODS: Determinants of AR were assessed in 313 consecutive patients who underwent TAVI with the Medtronic(MCS, n=259) or Edwards Sapien or XT(ESV, n=54) using MSCT- guided sizing. AR was assessed by angiography immediately after TAVI (n=313, Sellers) and by echocardiography at discharge (n=285, VARC-2)...
January 27, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28124228/the-role-of-msct-angiography-in-early-detection-of-lower-limb-arterial-lesions-in-patients-with-antiphospholipid-syndrome
#4
Jovica Saponjski, Ljudmila Stojanovich, Jelena Petrovic, Dusan Saponjski
Antiphospholipid syndrome (APS) is an autoimmune disease which is characterized by arterial and venous thromboses, fetal loss, and the presence of antiphospholipid antibodies in the serum. It is characterized by accelerated atherosclerosis. Increased tendency towards thrombosis leads to the occurrence of various vascular events. The objective of our study was to determine if there are subclinical changes on lower limb arteries in APS patients and what the best diagnostic choice for their establishment is. In this study, we analyzed 50 patients with primary antiphospholipid syndrome (PAPS) and 50 patients, who have secondary antiphospholipid syndrome (SAPS)...
January 25, 2017: Immunologic Research
https://www.readbyqxmd.com/read/28106077/mesenchymal-stem-cell-transplantation-in-tight-skin-mice-identifies-mir-151-5p-as-a-therapeutic-target-for-systemic-sclerosis
#5
Chider Chen, Dandan Wang, Alireza Moshaverinia, Dawei Liu, Xiaoxing Kou, Wenjing Yu, Ruili Yang, Lingyun Sun, Songtao Shi
Systemic sclerosis (SSc), an autoimmune disease, may cause significant osteopenia due to activation of the IL4Rα/mTOR pathway. Mesenchymal stem cell transplantation (MSCT) can ameliorate immune disorders in SSc via inducing immune tolerance. However, it is unknown whether MSCT rescues osteopenia phenotype in SSc. Here we show that MSCT can effectively ameliorate osteopenia in SSc mice by rescuing impaired lineage differentiation of the recipient bone marrow MSCs. Mechanistically, we show that donor MSCs transfer miR-151-5p to the recipient bone marrow MSCs in SSc mice to inhibit IL4Rα expression, thus downregulating mTOR pathway activation to enhance osteogenic differentiation and reduce adipogenic differentiation...
January 20, 2017: Cell Research
https://www.readbyqxmd.com/read/28075426/age%C3%A2-adjusted-plasma-d%C3%A2-dimer-levels-in-suspected-acute-pulmonary-embolism-a-retrospective-single%C3%A2-center-study
#6
Marta Kozłowska, Magdalena Pływaczewska, Michał Ciurzyński, Szymon Pacho, Marzanna Paczyńska, Zenon Truszewski, Maciej Kostrubiec, Anna Wyzgał, Piotr Palczewski, Marcin Koć, Dorota Matuszewicz, Piotr Pruszczyk
INTRODUCTION The conventional D‑dimer threshold (CDD) is characterized by high sensitivity and low specificity in diagnosing acute pulmonary embolism (PE) in older patients. A higher cut‑off level for D‑dimer has been proposed, aiming at increasing the specificity while maintaining high sensitivity. It is calculated by multiplying the patient's age in years by a coefficient of 10 (YADD10). OBJECTIVES The aim of this study was to validate the clinical value of YADD10 in patients with suspected acute PE and to optimize this threshold to achieve increased specificity paired with high sensitivity...
January 10, 2017: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/28045346/utility-of-fusion-volumetric-images-from-computed-tomography-and-magnetic-resonance-imaging-for-localizing-the-mandibular-canal
#7
Chutamas Deepho, Hiroshi Watanabe, Shinya Kotaki, Junichiro Sakamoto, Yasunori Sumi, Tohru Kurabayashi
OBJECTIVES: The purpose of this study is to investigate whether computed tomography/magnetic resonance imaging (CT/MRI) fusion volumetric images can improve the detectability of the mandibular canal (MC) compared to CT alone. METHODS: Images of 31 lesions within or close to the mandible using both multi-slice CT (MSCT) and MRI were gathered from our imaging archives. All lesions underwent MSCT and three dimensional volumetric interpolated breath-hold examination (3D-VIBE) MRI...
January 3, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/27990508/quantification-of-bone-quality-using-different-cone-beam-computed-tomography-devices-accuracy-assessment-for-edentulous-human-mandibles
#8
Jeroen Van Dessel, Laura Ferreira Pinheiro Nicolielo, Yan Huang, Pieter Slagmolen, Constantinus Politis, Ivo Lambrichts, Reinhilde Jacobs
PURPOSE: To determine the accuracy of the latest cone beam computed tomography (CBCT) machines in comparison to multi-slice computer tomography (MSCT) and micro computed tomography (micro-CT) for objectively assessing trabecular and cortical bone quality prior to implant placement. MATERIALS AND METHODS: Eight edentulous human mandibular bone samples were scanned with seven CBCT scanners (3D Accuitomo 170, i-CAT Next Generation, ProMax 3D Max, Scanora 3D, Cranex 3D, Newtom GiANO and Carestream 9300) and one MSCT system (Somatom Definition Flash) using the clinical exposure protocol with the highest resolution...
2016: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/27973335/non-invasive-heart-team-assessment-of-multivessel-coronary-disease-with-coronary-computed-tomography-angiography-based-on-syntax-score-ii-treatment-recommendations-design-and-rationale-of-the-randomized-syntax-iii-revolution-trial
#9
Rafael Cavalcante, Yoshinobu Onuma, Yohei Sotomi, Carlos Collet, Brian Thomsen, Campbell Rogers, Yaping Zeng, Erhan Tenekecioglu, Taku Asano, Yosuke Miyasaki, Mohammad Abdelghani, Marie-Angèle Morel, Patrick W Serruys
AIMS: To investigate whether a heart-team decision-making process regarding the choice of revascularization strategy based on non-invasive coronary multislice computed tomography angiography (MSCT) assessment of coronary artery disease (CAD) is equivalent to the standard-of-care invasive angiography based assessment in patients with multivessel CAD. METHODS AND RESULTS: The SYNTAX III Revolution trial is a prospective, multicenter, all-comers randomized trial that will randomize two Heart-Teams to select between surgical or percutaneous treatment according to either an invasive conventional angiography or a non-invasive MSCT angiography assessment in patients with multivessel CAD...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27970098/tct-716-a-dw-mri-and-msct-study-to-assess-predictors-of-cerebral-embolism-during-transcatheter-aortic-valve-implantation
#10
Ermela Yzeiraj, Klaudija Bijuklic, Timo Haselbach, Korff Krause, Julian Witt, Lorenz Hansen, Friedrich-Christian Riess, Joachim Schofer
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27960216/dilatation-of-vascular-prostheses-in-ascending-aortic-position-a-long-term-follow-up-computed-tomography-study-with-comparison-of-different-measurement-methods
#11
Marwan Hamiko, Matthias Endlich, Christian Krämer, Chris Probst, Armin Welz, Kai Wilhelm, Wolfgang Schiller
Background The aim of this study was to evaluate long-term dilatation of Hemashield Gold and Hemashield Platinum vascular prostheses in ascending aortic position using different measurement methods to obtain precise results. Methods Between 1999 and 2007, 73 patients with Stanford type A dissection received ascending aortic replacement with Hemashield Gold and Hemashield Platinum prostheses. Measurements were performed using multiplanar reconstruction mode of electrocardiogram (ECG)-gated, multislice spiral computed tomography (MSCT) in strictly orthogonal cross-sectional planes...
December 13, 2016: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27939592/evaluation-of-the-accuracy-of-linear-measurements-on-multi-slice-and-cone-beam-computed-tomography-scans-to-detect-the-mandibular-canal-during-bilateral-sagittal-split-osteotomy-of-the-mandible
#12
B Freire-Maia, V deC Machado, C S Valerio, A L N Custódio, F R Manzi, J L C Junqueira
The aim of this study was to compare the accuracy of linear measurements of the distance between the mandibular cortical bone and the mandibular canal using 64-detector multi-slice computed tomography (MSCT) and cone beam computed tomography (CBCT). It was sought to evaluate the reliability of these examinations in detecting the mandibular canal for use in bilateral sagittal split osteotomy (BSSO) planning. Eight dry human mandibles were studied. Three sites, corresponding to the lingula, the angle, and the body of the mandible, were selected...
March 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27907931/coronary-artery-anomalies-diagnosis-and-classification-based-on-cardiac-ct-and-mri-cmr-from-alcapa-to-anomalies-of-termination
#13
Philipp Heermann, Walter Heindel, Christoph Schülke
Background Coronary artery anomalies encompass a clinically and anatomically variable spectrum including physiological variants and pathophysiologically relevant anomalies. The majority of the variants has no hemodynamic relevance and is often detected accidentally. The recognition of the rare and relevant anomalies that cause either relevant shunt volumes leading to myocardial ischemia or ventricular tachyarrhythmias with the risk of sudden cardiac death is of major importance. Methods This review is based on a literature search in PubMed conducted using the key words "coronary artery" and/or "anomaly" and/or "anomalous origin" and/or "myocardial bridging" and/or "coronary artery fistula" and/or "Bland-White-Garland" and/or "ALCAPA"...
January 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/27885641/apophyseal-ossification-of-the-iliac-crest-in-forensic-age-estimation-computed-tomography-standards-for-modern-australian-subadults
#14
Nicolene Lottering, Clair L Alston-Knox, Donna M MacGregor, Maree T Izatt, Caroline A Grant, Clayton J Adam, Laura S Gregory
This study contrasts the ontogeny of the iliac crest apophysis using conventional radiography and multislice computed tomography (MSCT), providing probabilistic information for age estimation of modern Australian subadults. Retrospective abdominopelvic MSCT data acquired from 524 Australian individuals aged 7-25 and surveillance radiographs of adolescent idiopathic scoliosis patients included in the Paediatric Spine Research Group Progression Study (n = 531) were assessed. Ossification scoring of pseudo-radiographs and three-dimensional (3D) volume-rendered reconstructions using Risser (1958) quantitative descriptors indicate discrepancies in age estimates, stage allocation, and conflicting morphological progression...
November 25, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27867455/diagnostic-accuracy-of-computed-tomography-angiography-as-compared-to-conventional-angiography-in-patients-undergoing-noncoronary-cardiac-surgery
#15
Hasit Joshi, Ronak Shah, Jayesh Prajapati, Vipin Bhangdiya, Jayal Shah, Yogini Kandre, Komal Shah
OBJECTIVE: To compare the diagnostic accuracy of multi-slice computed tomography (MSCT) angiography with conventional angiography in patients undergoing major noncoronary cardiac surgeries. MATERIALS AND METHODS: We studied fifty major noncoronary cardiac surgery patients scheduled for invasive coronary angiography, 29 (58%) female and 21 (42%) male. Inclusion criteria of the study were age of the patients ≥40 years, having low or intermediate probability of coronary artery disease (CAD), left ventricular ejection fraction (LVEF) >35%, and patient giving informed consent for undergoing MSCT and conventional coronary angiography...
July 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27866545/-value-of-low-dose-multi-slice-spiral-ct-chest-scan-in-diagnosis-of-coal-workers-pneumoconiosis
#16
P Du, A H Cao, Z W Guo, Q Shao, K Xu
Objective: To investigate the value of low-dose multi-slice CT (MSCT) chest scan in the diagnosis of coal workers' pneumoconiosis. Methods: A total of 90 patients with a confirmed diagnosis of coal workers' pneumoconiosis were enrolled, and under the conditions of fixed tube voltage, pitch, and slice thickness, they underwent CT scan with a normal dose (150 mA) and a low dose (30-50 mA). The quality of images obtained from two scans was compared, and the imaging findings, opacity profusion, stage, and radiation doses were also compared...
September 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/27856928/prevalence-of-congenital-coronary-artery-anomalies-as-shown-by-multi-slice-computed-tomography-coronary-angiography-a-single-centre-study-from-turkey
#17
Aybala Tongut, Zeki Özyedek, İsmail Çerezci, Selim Erentürk, Ali Can Hatemi
OBJECTIVE: Coronary artery anomaly (CAA) is a remarkable etiological factor for sudden cardiac death in young adults. The incidence of CAA is unknown, with most reliable data available based on postmortem/angiography investigations. This study aimed to assess the prevalence of different forms of coronary anomalies, and to investigate the relationships between demographic data and occurrence of CAA. METHODS: A total of 2401 consecutive patients (1805 men; mean age, 56 ± 11...
November 17, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27846460/coronary-risk-stratification-of-patients-undergoing-surgery-for-valvular-heart-disease
#18
Rasmus Bo Hasselbalch, Thomas Engstrøm, Mia Pries-Heje, Merete Heitmann, Frants Pedersen, Morten Schou, Hans Mickley, Hanne Elming, Rolf Steffensen, Lars Køber, Kasper Iversen
BACKGROUND: Multislice computed tomography (MSCT) is a non-invasive, less expensive, low-radiation alternative to coronary angiography (CAG) prior to valvular heart surgery. MSCT has a high negative predictive value for coronary artery disease (CAD) but previous studies of patients with valvular disease have shown that MSCT, as the primary evaluation technique, lead to re-evaluation with CAG in about a third of cases and it is therefore not recommended. If a subgroup of patients with low- to intermediate risk of CAD could be identified and examined with MSCT, it could be cost-effective, reduce radiation and the risk of complications associated with CAG...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27845055/is-stem-cell-therapy-ready-for-prime-time-in-treatment-of-inflammatory-bowel-diseases
#19
Christopher J Hawkey, Daniel W Hommes
Autologous hematopoietic stem cell transplantation (HSCT) and mesenchymal stromal cell therapy have been proposed for patients with refractory Crohn's disease (CD) and fistulizing CD, respectively. Will these highly advanced techniques be available only for select patients, at specialized centers, or is further clinical development justified, with the aim of offering widespread, more definitive therapeutic options for often very difficult to treat disease? Patients with CD who are eligible for HSCT have typically been failed by most approved therapies, have undergone multiple surgeries, and have coped with years of disease activity and poor quality of life...
February 2017: Gastroenterology
https://www.readbyqxmd.com/read/27830891/morphometric-multislice-computed-tomography-examination-of-the-craniovertebral-junction-in-neck-flexion-and-extension
#20
Slobodan Marinkovic, Ivan Milić, Igor Djorić, Luciano Brigante, Aleksandar Miljatović, Laslo Puškaš, Slobodan Kapor, Jelena Boljanović
BACKGROUND: Detailed study of the craniovertebral junction (CVJ) is necessary to completely understand the mechanism of its flexion and extension. MATERIALS AND METHODS: One cadaver head was sectioned in the sagittal plane. Also, in 22 volunteers, examined using the multislice computerized tomography (MSCT), 14 parameters and 2 angles were measured in the neutral position, flexion and extension. RESULTS: The obtained measurements showed the anterior part of the occiput to move inferiorly in flexion, and the anterior atlas arch and the tip of the dens to get closer to the basion...
November 10, 2016: Folia Morphologica (Warsz)
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