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https://www.readbyqxmd.com/read/28334806/prognostic-value-of-eus-combined-with-msct-in-predicting-the-recurrence-and-metastasis-of-patients-with-gastric-cancer
#1
Jun-Hua Li, Wei-Zhong Shen, Xiao-Qing Gu, Wei-Kang Hong, Zhi-Qiang Wang
Objective: This study aims to explore the prognostic value of endoscopic ultrasonography combined with multi-slice spiral computed tomography in predicting the recurrence and metastasis of gastric cancer, as well as investigate the correlation of fragile histidine triad protein expression with the tumor-node-metastasis stage of gastric cancer patients. Methods: A total of 81 gastric cancer patients were selected in our study. All patients were examined by endoscopic ultrasonography and multi-slice spiral computed tomography before operation, and gastric cancer tissues and adjacent normal tissues were obtained after operation...
March 10, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28329198/long-term-serial-non-invasive-multislice-computed-tomography-angiography-with-functional-evaluation-after-coronary-implantation-of-a-bioresorbable-everolimus-eluting-scaffold-the-absorb-cohort-b-msct-substudy
#2
Yoshinobu Onuma, Carlos Collet, Robert-Jan van Geuns, Bernard de Bruyne, Evald Christiansen, Jacques Koolen, Pieter Smits, Bernard Chevalier, Dougal McClean, Dariusz Dudek, Stephan Windecker, Ian Meredith, Koen Nieman, Susan Veldhof, John Ormiston, Patrick W Serruys
Aims: Multimodality invasive imaging of the first-in-man cohort demonstrated at 5 years stable lumen dimensions and a low rate of major adverse cardiac events (MACE). However, the long-term non-invasive assessment of this device remains to be documented. The objective was to describe the 72-month multislice computed tomography (MSCT) angiographic and functional findings after the implantation of the second iteration of the fully resorbable everolimus-eluting polymeric scaffold. Methods and results: In the ABSORB Cohort B trial patients with non-complex de novo lesions were treated with second iteration bioresobable vascular scaffold (BVS)...
March 16, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28327698/accuracy-and-reliability-of-different-cone-beam-computed-tomography-cbct-devices-for-structural-analysis-of-alveolar-bone-in-comparison-with-multislice-ct-and-micro-ct
#3
Jeroen Van Dessel, Laura Ferreira Pinheiro Nicolielo, Yan Huang, Walter Coudyzer, Benjamin Salmon, Ivo Lambrichts, Reinhilde Jacobs
OBJECTIVE: The aim of this study was to assess whether cone beam computed tomography (CBCT) may be used for clinically reliable alveolar bone quality assessment in comparison to its clinical alternatives, multislice computed tomography and the gold standard (micro-CT). MATERIALS AND METHODS: Six dentate mandibular bone samples were scanned with seven CBCT devices (ProMax 3D Max, NewTom GiANO, Cranex 3D, 3D Accuitomo 170, Carestream 9300, Scanora 3D, I-CAT Next generation), one micro-CT scanner (SkyScan 1174) and one MSCT machine (Somatom Definition Flash) using two protocols (standard and high-resolution)...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28326166/trail-delivery-by-msc-derived-extracellular-vesicles-is-an-effective-anticancer-therapy
#4
ZhengQiang Yuan, Krishna K Kolluri, Kate H C Gowers, Sam M Janes
Extracellular vesicles (EVs) are lipid membrane-enclosed nanoparticles released by cells. They mediate intercellular communication by transferring biological molecules and therefore have potential as innovative drug delivery vehicles. TNF-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis of cancer cells. Unfortunately, the clinical application of recombinant rTRAIL has been hampered by its low bioavailability and resistance of cancer cells. EV-mediated TRAIL delivery may circumvent these problems...
2017: Journal of Extracellular Vesicles
https://www.readbyqxmd.com/read/28321342/presurgical-cone-beam-computed-tomography-bone-quality-evaluation-for-predictable-immediate-implant-placement-and-restoration-in-esthetic-zone
#5
Corina Marilena Cristache
Despite numerous advantages over multislice computed tomography (MSCT), including a lower radiation dose to the patient, shorter acquisition times, affordable cost, and sometimes greater detail with isotropic voxels used in reconstruction, allowing precise measurements, cone beam computed tomography (CBCT) is still controversial regarding bone quality evaluation. This paper presents a brief review of the literature on accuracy and reliability of bone quality assessment with CBCT and a case report with step-by-step predictable treatment planning in esthetic zone, based on CBCT scans which enabled the clinician to evaluate, depending on bone volume and quality, whether immediate restoration with CAD-CAM manufactured temporary crown and flapless surgery may be a treatment option...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28306334/impact-of-prone-supine-and-oblique-patient-positioning-on-cbct-image-quality-contrast-to-noise-ratio-and-figure-of-merit-value-in-the-maxillofacial-region
#6
Juha Koivisto, Maureen van Eijnatten, Jorma Järnstedt, Kirsi Holli-Helenius, Prasun Dastidar, Jan Wolff
OBJECTIVES: To assess the impact of supine, prone and oblique patient imaging positions on the image quality, contrast-to-noise ratio and figure of merit value in the maxillofacial region using a cone beam computed tomography scanner. Furthermore, the CBCT supine images were compared to supine MSCT images. METHODS: One fresh frozen cadaver head was scanned in prone, supine and oblique imaging positions using a mobile CBCT scanner. MSCT images of the head were acquired in a supine position...
March 17, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28292512/clinicopathological-and-multisection-ct-features-of-primary-pulmonary-mucoepidermoid-carcinoma
#7
D-L Cheng, Y-X Hu, P-Q Hu, G Wen, K Liu
AIM: To delineate the multisection computed tomography (MSCT) features and the clinical characteristics of primary pulmonary mucoepidermoid carcinoma (PMEC). Prognostic factors were also analysed. MATERIALS AND METHODS: A retrospective study was undertaken to investigate the medical records and MSCT performance of histopathologically confirmed PMECs from 2007 to 2015. RESULTS: A total of 83.3% of patients with high-grade PMECs were aged >40 years, whereas there were 1...
March 11, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28248153/hepatic-angiodynamic-profile-in-paediatric-patients-with-hereditary-haemorrhagic-telangiectasia-type-1-and-type-2
#8
Paola Giordano, Mariantonietta Francavilla, Paolo Buonamico, Patrizia Suppressa, Patrizia Lastella, Maria Sangerardi, Vito L Miniello, Arnaldo Scardapane, Gennaro M Lenato, Carlo Sabbà
Liver involvement is a common manifestation of hereditary haemorrhagic telangiectasia (HHT). Although a number of studies have been carried out in adult patients, no study has ever been focused on investigating HHT-related hepatic involvement in paediatric patients. The present study aimed for the first time to systematically estimate the prevalence of HHT-associated liver involvement and to characterize HHT-associated hepatic angiodynamic features in paediatric age. Patients and methods: The study was designed as a cross-sectional survey in an HHT paediatric cohort, subclassified as HHT1 and HHT2 according to the mutated gene...
March 1, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28247656/-litholytic-therapy-for-urate-nephrolithiasis
#9
S Kh Al'-Shukri, M N Slesarevskaya, I V Kuz'min
AIM: To evaluate the effectiveness of ESWL combined with litholytic therapy in patients with uric acid kidney stones. MATERIALS AND METHODS: A total of 59 patients with urate nephrolithiasis were observed at the Department of Urology, First Pavlov SMU of St. Peterburg. The patients were divided into two groups according to the treatment regimen. The study group comprised 30 patients who were administered litholytic therapy before ESWL. The comparison group included 29 patients with nephrolithiasis who underwent ESWL without prior litholytic therapy...
April 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28224428/a-new-method-of-3-dimensional-localization-of-intraocular-foreign-bodies-using-ct-imaging-a-role-of-optic-nerve
#10
Qi Yao, Han-Ping Wu, Bin Xiong, Ping Han, Chuan-Sheng Zheng
Computed tomography (CT) is considered the most sensitive method for the detection of intraocular foreign bodies (IOFBs). The purpose of this study was to evaluate a new method of 3-dimentional (3D) localization of IOFBs that takes advantage of the anatomical structure of the optic nerve and to assess the clinical outcomes using this new method. Twenty-two trauma patients with IOFBs or suspected IOFBs admitted to our hospital were scanned with multislice CT (MSCT) between July and December 2003. All scanning was performed with a 16-row spiral CT in axial plane using a sequential scanning protocol...
February 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28217916/effects-of-allogeneic-mesenchymal-stem-cell-transplantation-in-the-treatment-of-liver-cirrhosis-caused-by-autoimmune-diseases
#11
Jun Liang, Huayong Zhang, Cheng Zhao, Dandan Wang, Xiaolei Ma, Shengnan Zhao, Shiying Wang, Lingying Niu, Lingyun Sun
AIM: There has been great interest in recent years to take advantage of mesenchymal stem cells (MSCs) to treat end-stage liver disease. This study is aimed to evaluate clinical therapeutic effects of allogeneic MSC transplantation in liver cirrhosis caused by autoimmune diseases. METHODS: The enrolled patients with liver cirrhosis were assigned to receive allogeneic MSC infusions through a peripheral vein. The primary objective of this study was to assess the safety and effectiveness of MSCT in patients with autoimmune diseases-induced cirrhosis...
February 20, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28150295/impact-of-corevalve-size-selection-based-on-multi-slice-computer-tomography-on-paravalvular-leak-after-transcatheter-aortic-valve-implantation
#12
Piotr Chodór, Krzysztof Wilczek, Roman Przybylski, Jan Głowacki, Tomasz Kukulski, Witold Streb, Tomasz Niklewski, Grzegorz Honisz, Przemysław Trzeciak, Tomasz Podolecki, Łukasz Włoch, Marian Zembala, Zbigniew Kalarus
BACKGROUND: Paravalvular leak (PVL) has significant impact on long-term outcomes in patients after transcatheter aortic valve implantation (TAVI). This study sought to determine whether multi-slice computed tomography (MSCT)-guided valve selection reduces PVL after CoreValve implantation. METHODS: The analysis encompassed 69 patients implanted with CoreValve and were divided into two groups. In Group I (30 patients), valve selection was based on standard procedures, in Group II (39 pts), on MSCT measurements...
February 2, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28150269/applications-of-digital-technology-for-the-morphological-study-of-c3-c7-vertebral-arch-pedicle-in-children
#13
S Zhang, X Wang, X Ren, Z Li, Y Zhang
BACKGROUND: This study aims to investigate the morphological characteristics and developmental patterns of the vertebral arch pedicle (VAP) in the lower cervical vertebrae of children, and to subsequently help guide the implantation of the pedicle screw. METHODS: The cervical vertebral multi-slice computed tomography (MSCT) data of 60 pediatric patients aged 4 to 12 years were collected and grouped. A reconstructed 3D model measured the following: pedicle width (PW), pedicle height (PH), pedicle osseous channel (POCL), pedicle transverse angle (PTA, namely the E angle), and pedicle sagittal angle (PTA, namely the F angle)...
February 2, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28128540/determinants-of-aortic-regurgitation-after-transcatheter-aortic-valve-implantation-an-observational-study-using-multi-slice-computed-tomography-msct-guided-sizing
#14
Zouhair Rahhab, Nahid El Faquir, Ramón Rodríguez-Olivares, Claire Ren, Nicolas VAN Mieghem, Marcel L Geleijnse, Carl Schultz, Ron VAN Domburg, Peter P DE Jaegere
BACKGROUND: To explore the determinants of aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) using Multi Slice Computed Tomography (MSCT) instead of echocardiography-guided sizing. METHODS: Determinants of AR were assessed in 313 consecutive patients who underwent TAVI with the Medtronic(MCS, n=259) or Edwards Sapien or XT(ESV, n=54) using MSCT- guided sizing. AR was assessed by angiography immediately after TAVI (n=313, Sellers) and by echocardiography at discharge (n=285, VARC-2)...
January 27, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28124228/the-role-of-msct-angiography-in-early-detection-of-lower-limb-arterial-lesions-in-patients-with-antiphospholipid-syndrome
#15
Jovica Saponjski, Ljudmila Stojanovich, Jelena Petrovic, Dusan Saponjski
Antiphospholipid syndrome (APS) is an autoimmune disease which is characterized by arterial and venous thromboses, fetal loss, and the presence of antiphospholipid antibodies in the serum. It is characterized by accelerated atherosclerosis. Increased tendency towards thrombosis leads to the occurrence of various vascular events. The objective of our study was to determine if there are subclinical changes on lower limb arteries in APS patients and what the best diagnostic choice for their establishment is. In this study, we analyzed 50 patients with primary antiphospholipid syndrome (PAPS) and 50 patients, who have secondary antiphospholipid syndrome (SAPS)...
January 25, 2017: Immunologic Research
https://www.readbyqxmd.com/read/28106077/mesenchymal-stem-cell-transplantation-in-tight-skin-mice-identifies-mir-151-5p-as-a-therapeutic-target-for-systemic-sclerosis
#16
Chider Chen, Dandan Wang, Alireza Moshaverinia, Dawei Liu, Xiaoxing Kou, Wenjing Yu, Ruili Yang, Lingyun Sun, Songtao Shi
Systemic sclerosis (SSc), an autoimmune disease, may cause significant osteopenia due to activation of the IL4Rα/mTOR pathway. Mesenchymal stem cell transplantation (MSCT) can ameliorate immune disorders in SSc via inducing immune tolerance. However, it is unknown whether MSCT rescues osteopenia phenotype in SSc. Here we show that MSCT can effectively ameliorate osteopenia in SSc mice by rescuing impaired lineage differentiation of the recipient bone marrow MSCs. Mechanistically, we show that donor MSCs transfer miR-151-5p to the recipient bone marrow MSCs in SSc mice to inhibit IL4Rα expression, thus downregulating mTOR pathway activation to enhance osteogenic differentiation and reduce adipogenic differentiation...
January 20, 2017: Cell Research
https://www.readbyqxmd.com/read/28075426/age%C3%A2-adjusted-plasma-d%C3%A2-dimer-levels-in-suspected-acute-pulmonary-embolism-a-retrospective-single%C3%A2-center-study
#17
Marta Kozłowska, Magdalena Pływaczewska, Michał Ciurzyński, Szymon Pacho, Marzanna Paczyńska, Zenon Truszewski, Maciej Kostrubiec, Anna Wyzgał, Piotr Palczewski, Marcin Koć, Dorota Matuszewicz, Piotr Pruszczyk
INTRODUCTION The conventional D‑dimer threshold (CDD) is characterized by high sensitivity and low specificity in diagnosing acute pulmonary embolism (PE) in older patients. A higher cut‑off level for D‑dimer has been proposed, aiming at increasing the specificity while maintaining high sensitivity. It is calculated by multiplying the patient's age in years by a coefficient of 10 (YADD10). OBJECTIVES The aim of this study was to validate the clinical value of YADD10 in patients with suspected acute PE and to optimize this threshold to achieve increased specificity paired with high sensitivity...
January 10, 2017: Pol Arch Intern Med
https://www.readbyqxmd.com/read/28045346/utility-of-fusion-volumetric-images-from-computed-tomography-and-magnetic-resonance-imaging-for-localizing-the-mandibular-canal
#18
Chutamas Deepho, Hiroshi Watanabe, Shinya Kotaki, Junichiro Sakamoto, Yasunori Sumi, Tohru Kurabayashi
OBJECTIVES: The purpose of this study was to investigate whether CT/MRI fusion volumetric images can improve the detectability of the mandibular canal (MC) compared with CT alone. METHODS: Images of 31 lesions within or close to the mandible using both multislice CT (MSCT) and MRI were gathered from our imaging archives. All lesions underwent MSCT and three-dimensional volumetric interpolated breath-hold examination (3D-VIBE) MRI. Of the 62 hemimandibles, 13 hemimandibles were excluded because the MC passed through a lesion...
February 17, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/27990508/quantification-of-bone-quality-using-different-cone-beam-computed-tomography-devices-accuracy-assessment-for-edentulous-human-mandibles
#19
Jeroen Van Dessel, Laura Ferreira Pinheiro Nicolielo, Yan Huang, Pieter Slagmolen, Constantinus Politis, Ivo Lambrichts, Reinhilde Jacobs
PURPOSE: To determine the accuracy of the latest cone beam computed tomography (CBCT) machines in comparison to multi-slice computer tomography (MSCT) and micro computed tomography (micro-CT) for objectively assessing trabecular and cortical bone quality prior to implant placement. MATERIALS AND METHODS: Eight edentulous human mandibular bone samples were scanned with seven CBCT scanners (3D Accuitomo 170, i-CAT Next Generation, ProMax 3D Max, Scanora 3D, Cranex 3D, Newtom GiANO and Carestream 9300) and one MSCT system (Somatom Definition Flash) using the clinical exposure protocol with the highest resolution...
2016: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/27973335/non-invasive-heart-team-assessment-of-multivessel-coronary-disease-with-coronary-computed-tomography-angiography-based-on-syntax-score-ii-treatment-recommendations-design-and-rationale-of-the-randomized-syntax-iii-revolution-trial
#20
Rafael Cavalcante, Yoshinobu Onuma, Yohei Sotomi, Carlos Collet, Brian Thomsen, Campbell Rogers, Yaping Zeng, Erhan Tenekecioglu, Taku Asano, Yosuke Miyasaki, Mohammad Abdelghani, Marie-Angèle Morel, Patrick W Serruys
AIMS: To investigate whether a heart-team decision-making process regarding the choice of revascularization strategy based on non-invasive coronary multislice computed tomography angiography (MSCT) assessment of coronary artery disease (CAD) is equivalent to the standard-of-care invasive angiography based assessment in patients with multivessel CAD. METHODS AND RESULTS: The SYNTAX III Revolution trial is a prospective, multicenter, all-comers randomized trial that will randomize two Heart-Teams to select between surgical or percutaneous treatment according to either an invasive conventional angiography or a non-invasive MSCT angiography assessment in patients with multivessel CAD...
December 15, 2016: EuroIntervention
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