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researches on herbal medicinal plants

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https://www.readbyqxmd.com/read/29773013/critical-review-on-curcumin-as-a-therapeutic-agent-from-traditional-herbal-medicine-to-an-ideal-therapeutic-agent
#1
Muhammad Usman Akbar, Kanwal Rehman, Khalid Mahmood Zia, Muhammad Imran Qadir, Muhammad Sajid Hamid Akash, Muhammad Ibrahim
Traditionally, many natural medicinal plants have been used to treat a variety of diseases since ancient times and are considered a potential source of phytochemicals for the development of new drugs. One of these is curcumin, which is an easily accessible, inexpensive, and nontoxic bioactive compound. Curcumin is a very important, naturally occurring, and highly lipophilic and phenolic substance derived from the rhizomes of plant Curcuma longa, a member of the Zingiberaceae (ginger) family, which is mostly used as a curry spice, flavoring agent, insect repellent, coloring agent in food, traditional drug, and ingredient in cosmetics...
2018: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/29770277/a-strategy-to-find-novel-candidate-anti-alzheimer-s-disease-drugs-by-constructing-interaction-networks-between-drug-targets-and-natural-compounds-in-medical-plants
#2
Bi-Wen Chen, Wen-Xing Li, Guang-Hui Wang, Gong-Hua Li, Jia-Qian Liu, Jun-Juan Zheng, Qian Wang, Hui-Juan Li, Shao-Xing Dai, Jing-Fei Huang
Background: Alzheimer' disease (AD) is an ultimately fatal degenerative brain disorder that has an increasingly large burden on health and social care systems. There are only five drugs for AD on the market, and no new effective medicines have been discovered for many years. Chinese medicinal plants have been used to treat diseases for thousands of years, and screening herbal remedies is a way to develop new drugs. Methods: We used molecular docking to screen 30,438 compounds from Traditional Chinese Medicine (TCM) against a comprehensive list of AD target proteins...
2018: PeerJ
https://www.readbyqxmd.com/read/29751724/-textual-research-on-origin-and-genuine-of-lilii-bulbus
#3
Chang-Hua Wang, Shu Shu, Fu-Jun Yin, Ji-Feng Zhao, Zhi-Wei Zhang, Xiang Liu, Zhi-Lai Zhan
Lilii Bulbus, which comes from many medicinal plants,is a frequently-used traditional Chinese medicine,the records in previous herbal literatures of it's origin and quality were inconstant. To trace back it's sources, we conducted a systematical study on it's origin and quality by textual research and investigation in this paper,The result showed that the origins of Lilii Bulbus are mainly source from white-flowers, red-yellow-flowers and red-flowers of Lilium, L. brownii var. viridulum, which were believed authentic or good quality in all previous herbal literatures,and L...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751696/-research-of-pollution-free-and-precision-cultivation-system-of-chinese-herbal-medicines
#4
Shi-Lin Chen, Lin-Lin Dong, Qiao-Sheng Guo, Jian-He Wei, Xi-Wen Li, Gang Li, Qi Li, Yu-de Liu, Si-Jing Liu, Hong Xu, Yu-Qi Yu, Jie Wu, Chong-Heng Liang
The issues of disordering production and non-standard pesticide application are common in the production of Chinese herbal medicines. Aimed to above problems, research groups built the pollution-free and precision cultivation system of medicinal plants. This system mainly included the precise site selection of medicinal plants based on the GIS technology, modern omics-assisted breeding, metagenomics guiding the soil complex improvement, and the precise field management based on rational application of fertilizer and comprehensive control of disease...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751644/protective-effects-of-selected-botanical-agents-on-bone
#5
REVIEW
James Jam Jolly, Kok-Yong Chin, Ekram Alias, Kien Hui Chua, Ima Nirwana Soelaiman
Osteoporosis is a serious health problem affecting more than 200 million elderly people worldwide. The early symptoms of this disease are hardly detectable. It causes progressive bone loss, which ultimately renders the patients susceptible to fractures. Osteoporosis must be prevented because the associated fragility fractures result in high morbidity, mortality, and healthcare costs. Many plants used in herbal medicine contain bioactive compounds possessing skeletal protective effects. This paper explores the anti-osteoporotic properties of selected herbal plants, including their actions on osteoblasts (bone forming cells), osteoclasts (bone resorbing cells), and bone remodelling...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29736939/effects-of-silymarin-on-the-metabolic-syndrome-a-review
#6
REVIEW
Maryam Vahabzadeh, Nafise Amiri, Gholamreza Karimi
BACKGROUND: The metabolic syndrome is one of the rising global health problems and medical challenges due to several clinical complications it may cause, for example increasing the risk of myocardial infarction and hypertension. On the other hand, great attention has been directed toward determining the worthiness of herbal medicines. There are emerging studies on preventive and therapeutic effects of silymarin on different components of the metabolic syndrome. Extracted from the dried seeds of milk thistle plant (Silybum marianum L...
May 7, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29734769/novel-natural-products-for-healthy-ageing-from-the-mediterranean-diet-and-food-plants-of-other-global-sources-the-medihealth-project
#7
Birgit Waltenberger, Maria Halabalaki, Stefan Schwaiger, Nicolas Adamopoulos, Noureddine Allouche, Bernd L Fiebich, Nina Hermans, Pidder Jansen-Dürr, Victor Kesternich, Luc Pieters, Stefan Schönbichler, Alexios-Leandros Skaltsounis, Hung Tran, Ioannis P Trougakos, Alvaro Viljoen, Jean-Luc Wolfender, Christian Wolfrum, Nikos Xynos, Hermann Stuppner
There is a rapid increase in the percentage of elderly people in Europe. Consequently, the prevalence of age-related diseases will also significantly increase. Therefore, the main goal of MediHealth, an international research project, is to introduce a novel approach for the discovery of active agents of food plants from the Mediterranean diet and other global sources that promote healthy ageing. To achieve this goal, a series of plants from the Mediterranean diet and food plants from other origins are carefully selected and subjected to in silico, cell-based, in vivo (fly and mouse models), and metabolism analyses...
May 6, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29725354/src-is-a-prime-target-inhibited-by-celtis-choseniana-methanol-extract-in-its-anti-inflammatory-action
#8
Han Gyung Kim, Subin Choi, Jongsung Lee, Yo Han Hong, Deok Jeong, Keejung Yoon, Deok Hyo Yoon, Gi-Ho Sung, Seungihm Lee, Suntaek Hong, Young-Su Yi, Jong-Hoon Kim, Jae Youl Cho
Celtis choseniana is the traditional plant used at Korea as a herbal medicine to ameliorate inflammatory responses. Although Celtis choseniana has been traditionally used as a herbal medicine at Korea, no systemic research has been conducted on its anti-inflammatory activity. Therefore, the present study explored an anti-inflammatory effect and its underlying molecular mechanism using Celtis choseniana methanol extract (Cc-ME) in macrophage-mediated inflammatory responses. In vitro anti-inflammatory activity of Cc-ME was evaluated using RAW264...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29725269/extraction-process-component-analysis-and-in-vitro-antioxidant-antibacterial-and-anti-inflammatory-activities-of-total-flavonoid-extracts-from-abutilon-theophrasti-medic-leaves
#9
Chunlian Tian, Peng Zhang, Caixia Yang, Xiang Gao, Hong Wang, Yuru Guo, Mingchun Liu
The flavonoid fraction was extracted from the leaves of Abutilon theophrasti Medic., which are usually used as a traditional Chinese herbal medicine for the treatment of inflammation and joint pain. The current study focused on the extraction process, component analysis, and in vitro antioxidant, antibacterial, and anti-inflammatory activities of the flavonoid fraction as a part of ongoing research on bioactive substances from natural plant sources. This study evaluated the antioxidant activities via assays of DPPH radical scavenging capacity, ABTS radical scavenging capacity, and reducing power and investigated inhibitory activities against Escherichia coli , Salmonella , Staphylococcus aureus , and Streptococcus ...
2018: Mediators of Inflammation
https://www.readbyqxmd.com/read/29710458/centaurea-albonitens-extract-enhances-the-therapeutic-effects-of-vincristine-in-leukemic-cells-by-inducing-apoptosis
#10
Forouzan Bahmani, Somayeh Esmaeili, Davood Bashash, Nasrin Dehghan-Nayeri, Pargol Mashati, Ahmad Gharehbaghian
Drug-induced toxicities and dose-related side effects are the major challenges in the conventional cancer therapy by the chemo drugs. On the other hand, herbal derivatives have obtained a great research interest in the field of therapeutic applications because of their more favorable specifications including less toxicity, cost-effective and more physiologically compatible than the chemical drugs. For this purpose, we evaluated methanolic extract prepared from Centaurea albonitens Turrill alone and in combination with Vincristine (VCR) for its potential cytotoxic effects in NALM-6, REH, NB4 and KMM-1 cell lines by using the various approaches...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29710046/new-compounds-and-potential-candidates-for-drug-discovery-from-medicinal-plants-of-vietnam
#11
Phan Minh Giang, Hideaki Otsuka
The study of natural products introduces interesting new bioorganic structures and potential candidates for the drug discovery stage in the development of innovative drugs. Vietnam enjoys a broad biodiversity of native plant species, microorganisms, marine organisms, and a long tradition of using herbal remedies. Thus, the study of medicinal plants in determining the basis of their efficacy and safety is an important task for modern researchers in Vietnam. The present review covers literature on new compounds elucidated from the systematic study of medicinal plants within some popular genera in Vietnam, as well as their significant biological activities...
2018: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29705516/icones-plantarum-malabaricarum-early-18th-century-botanical-drawings-of-medicinal-plants-from-colonial-ceylon
#12
Tinde Van Andel, Ariane Scholman, Mieke Beumer
ETHNOPHARMACOLOGICAL RELEVANCE: From 1640-1796, the Dutch East India Company (VOC) occupied the island of Ceylon (now Sri Lanka). Several VOC officers had a keen interest in the medicinal application of the local flora. The Leiden University Library holds a two-piece codex entitled: Icones Plantarum Malabaricarum, adscriptis nominibus et viribus, Vol. I. & II. (Illustrations of Plants from the Malabar, assigned names and strength). This manuscript contains 262 watercolour drawings of medicinal plants from Sri Lanka, with handwritten descriptions of local names, habitus, medicinal properties and therapeutic applications...
April 27, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29683551/changes-in-the-range-of-the-medicinal-herb-eriocaulon-buergerianum-koern-eriocaulaceae-under-climate-change
#13
Yi-Fei Xie, Li Yang, Rongyan Deng, Min-Hao Chen, Xiao-Feng Luan, Elisa Gottardi, Zhi-Xiang Zhang
BACKGROUND: Eriocaulon buergerianum Koern. (Eriocaulaceae) is one of the most common and least expensive herbal medicines for eye diseases. This species is facing potential threats from climate change. Insufficient biogeographical knowledge of this plant species can hinder its effective management for long-term population survival. METHODS: We integrated ecological niche modelling (Biomod2) with 70 records of E. buergerianum and 8 environmental variables to estimate the changes in distribution over time...
April 23, 2018: Plant Biology
https://www.readbyqxmd.com/read/29681854/evidence-supports-tradition-the-in-vitro-effects-of-roman-chamomile-on-smooth-muscles
#14
Zsolt Sándor, Javad Mottaghipisheh, Katalin Veres, Judit Hohmann, Tímea Bencsik, Attila Horváth, Dezső Kelemen, Róbert Papp, Loránd Barthó, Dezső Csupor
The dried flowers of Chamaemelum nobile (L.) All. have been used in traditional medicine for different conditions related to the spasm of the gastrointestinal system. However, there have been no experimental studies to support the smooth muscle relaxant effect of this plant. The aim of our research was to assess the effects of the hydroethanolic extract of Roman chamomile, its fractions, four of its flavonoids (apigenin, luteolin, hispidulin, and eupafolin), and its essential oil on smooth muscles. The phytochemical compositions of the extract and its fractions were characterized and quantified by HPLC-DAD, the essential oil was characterized by GC and GC-MS...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29623832/herbs-with-potential-nephrotoxic-effects-according-to-traditional-persian-medicine-review-and-assessment-of-scientific-evidence
#15
Fatemeh Kolangi, Zahra Memariani, Mahboubeh Bozorgi, Seyyed Ali Mozaffarpur, Mohaddeseh Mirzapour
BACKGROUND: The increased use of herbal remedies particularly in patients with kidney diseases indicated the importance of studies which focused on nephrotoxic plants. OBJECTIVE: The present study aimed to review and assess the kidney-damaging herbs mentioned in the Persian medicine [PM] books. METHODS: The main PM books were searched for nephrotoxic herbs and their relevant reformers traditionally proposed for preventing renal damage. PubMed, Scopus and Google Scholar were investigated for evaluation of the scientific evidence relating to the nephrotoxicity of herbs...
April 3, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29618400/studies-on-antimicrobial-activity-and-kinetics-of-inhibition-by-plant-products-in-india-1990-2016
#16
Ramesh Kumar Sharma, Bhupendra Kumar Rana
The antimicrobial activity of herbal extracts or plant isolates has usually been evaluated in India using different antimicrobial susceptibility testing methods generally based on diffusion and dilution. There are different analytical approaches for the reliable evaluation of antimicrobial activity ascribed to medicinal plants against selected pathogenic microorganisms. Obtained results may provide scientific bases for the selective use of these natural plants as healing drugs, crop-protecting pesticides, or shelf-life-extending solutions...
April 4, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29600633/-herbal-textual-research-on-chinese-medicine-huangjing-polygonati-rhizoma-and-some-enlightenments
#17
Jing-Jing Liu, Jin-Ping Si
To clarify the change and development of the original plants, medicinal organs, traditional functions, resource distribution of "Huangjing"(Polygonati Rhizome), a traditional Chinese medicine, we investigated Polygonatum species on the ancient Chinese herbal texts. The name of "Nüwei" was first carried out in the book of Sheng Nong's Herbal Classic. Its effects included two aspects: one was similar to "Weirui"(Polygonati Odorati Rhizome, "Yuzhu"), that was tonifying, nourishing one's vitality, removing wind and dampness, settling five organs, making body lightness, keeping longevity and not being hungry; the second was alike to "Huangjing" recorded in the book of Ming Yi Bie Lu(Appendant Records of Famous Physicians)...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29599697/links-between-the-prophet-muhammad-pbuh-recommended-foods-and-disease-management-a-review-in-the-light-of-modern-superfoods
#18
REVIEW
Sharique A Ali, Naima Parveen, Ayesha S Ali
Nutrition and other bioactive natural products present in specific foods within a balanced diet play an indispensable role in maintaining and promoting human health. Plants are rich sources of a balanced nutrition because of high content of bioactive products; hence, most of them recently have acquired the status of superfoods. It has been used since ancient times for the treatment of various ailments, and these traditional medicines still remain as one of the most affordable and easily accessible sources of treatment in the primary health-care system...
March 2018: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29595103/application-of-medicinal-plants-as-a-source-for-therapeutic-agents-against-streptococcus-pyogenes-infections
#19
Adil Mohd, H P Vasantha Rupasinghe
Streptococcus pyogenes, a major human pathogen, causes a wide variety of invasive systemic infections such as acute pharyngitis, skin and soft-tissue infections, especially necrotizing fasciitis. This Gram-positive bacterium has an ability to form mature biofilm and this sessile lifestyle plays an important role in S. pyogenes pathogenicity. The virulence of these bacteria is further strengthened by its ability to communicate within the micro-colonies through quorum sensing. Most treatments are now aimed at either elimination of this bacterium or suppression of its virulence...
March 29, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29581980/mineral-and-phytochemical-profiles-and-antioxidant-activity-of-herbal-material-from-two-temperate-astragalus-species
#20
Bronislava Butkutė, Audronė Dagilytė, Raimondas Benetis, Audrius Padarauskas, Jurgita Cesevičienė, Vilma Olšauskaitė, Nijolė Lemežienė
Only a few species of the large Astragalus genus, widely used for medicinal purposes, have been thoroughly studied for phytochemical composition. The aim of our research was to investigate the rarely studied species A. glycyphyllos L. and A. cicer L. for the distribution of mineral elements and phytochemicals in whole plants at two growth stages and in morphological fractions. We also investigated the capacity of the plant extracts to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and to chelate ferrous ions...
2018: BioMed Research International
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