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Nephrolithiasis

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https://www.readbyqxmd.com/read/28646939/hounsfield-units-for-nephrolithiasis-predictive-power-for-the-clinical-urologist
#1
Andrew Cohen, Blake Anderson, Glenn Gerber
INTRODUCTION: We aim to determine the optimal method for measuring Hounsfield Units (HU) of calculi for the clinical urologist. MATERIALS AND METHODS: We present a single institution prospective study from 2014-2015 for 125 consecutive patients. Demographics, baseline characteristics, imaging, and stone analysis were collected. CT scanners and settings were heterogeneous. Hounsfield units were measured by use of ellipsoid tool and free hand outline by two independent urology graders using Philips iSite PACs...
June 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28638599/obesity-and-kidney-disease-hidden-consequences-of-the-epidemic
#2
Csaba P Kovesdy, Susan L Furth, Carmine Zoccali
Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease and also for chronic kidney disease (CKD). A high body mass index is one of the strongest risk factors for new-onset CKD. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing CKD in the long term...
February 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28634523/mallory-weiss-tear-after-violent-hiccups-a-rare-association
#3
Sankalp Dwivedi, Hussein Al-Hamid, Bradley J Warren
We present an unusual case of a 44-year-old male who developed violent hiccups soon after a ureteroscopy for nephrolithiasis; later, the forceful hiccups were followed by hematemesis. Upper esophagogastroduodenoscopy revealed Mallory-Weiss tears and esophageal erosions in the lower esophagus. Esophageal biopsy was unremarkable. The patient did not have a prior history of the gastrointestinal disorder. Although extracorporeal shock wave lithotripsy has on rare occasion been implicated in the development of gastrointestinal erosions, no such correlation exists for ureteroscopy and upper gastrointestinal bleeding in the management of nephrolithiasis...
January 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28631910/-prevalence-and-risk-factors-for-nephrolithiasis-among-young-rural-residents
#4
A V Sin'kov, I N Volosatova, G M Sin'kova, L A Nikolaeva
AIM: To determine the prevalence of nephrolithiasis, assess the significance of known risk factors, and identify new risk factors for nephrolithiasis among young rural residents. MATERIALS AND METHODS: This cross-sectional study was conducted in 5 settlements of the Irkutsk rural district of the Irkutsk region and involved 408 inhabitants (93 men, 315 women) aged from 18 to 47 years. The selection of candidates for the study was randomized. The response of the population was 81...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28631902/-comparative-estimation-of-antilithogenic-activity-of-porcine-kidney-derived-biomedical-substance-and-sodium-citrate-in-experimental-urolithiasis
#5
G V Pavlyashik, A Yu Zharikov, V I Kiselev
AIM: to compare the anti-lithogenic activity of biomedical substance derived from freeze-dried porcine kidney and sodium citrate. MATERIALS AND METHODS: The experiments were conducted on Wistar rats divided into three groups of 15 animals each: control group (disease control), comparison group (sodium citrate treatment) and experimental group (treatment with biomedical substance from porcine kidneys). Experimental urolithiasis was modeled using the ethylene glycol model...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28627398/stones-first-a-gas-pyelo-nephroscopy-strategy-for-laparoscopic-pyeloplasty-and-renal-stone-extraction
#6
C Kouriefs, F Georgiades, P Grange
OBJECTIVE: To report our experience on gas endoscopy as the first step of pelvi-ureteric junction (PUJ) obstruction repair when complicated by nephrolithiasis. MATERIALS AND METHODS: Stone formation due to urine stasis is a known complication PUJ obstruction and an indication for its surgical repair. The undisputed results of the Anderson-Hynes dismembered pyeloplasty make it a quasi-gold standard; however, the identification and extraction of calyceal stones through the laparoscopic route can be challenging...
June 13, 2017: Urology
https://www.readbyqxmd.com/read/28624518/role-of-gut-microbiota-against-calcium-oxalate
#7
REVIEW
Humaira Sadaf, Syed Irfan Raza, Syed Waqas Hassan
Nephrolithiasis is a condition marked by the presence or formation of stones in kidneys. Several factors contribute to kidney stones development such as environmental conditions, type of dietary intake, gender and gastrointestinal flora. Most of the kidney stones are composed of calcium phosphate and calcium oxalate, which enter in to the body through diet. Both sources of oxalates become dangerous when normal flora of gastrointestinal tract is disturbed. Oxalobacter and Lactobacillus species exist symbiotically in the human gut and prevent stone formation by altering some biochemical pathways through production of specific enzymes which help in the degradation of oxalate salts...
June 15, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28618678/re-mucin-1-increases-renal-trpv5-activity-in-vitro-and-urinary-level-associates-with-calcium-nephrolithiasis-in-patients
#8
Dean G Assimos
No abstract text is available yet for this article.
July 2017: Journal of Urology
https://www.readbyqxmd.com/read/28616590/combination-of-extracorporeal-shockwave-lithotripsy-and-ureteroscopy-for-large-staghorn-calculi-in-a-pediatric-patient-case-report
#9
Austin J Schults, Wanjian Jia, Michael C Ost, Siam Oottamasathien
Background: Extracorporeal shockwave lithotripsy (SWL) is a procedure commonly performed to treat nephrolithiasis, with promising results in pediatric patients. However, increasing renal calculi size is directly related to worsening stone-free rates. There are few reports in the literature of >2-cm staghorn calculi that expound on the exact mechanism of treatment in the pediatric population. Case Presentation: We present a case report of a 3-year-old boy who presented with a large 3-cm staghorn calculi effectively treated with one session of SWL followed by a planned staged ureteroscopy for definitive treatment...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/28614116/parathyroid-hormone-and-the-regulation-of-renal-tubular-calcium-transport
#10
Benjamin Ko
PURPOSE OF REVIEW: Renal tubule excretion of calcium is carefully and complexly regulated. At the center of this process, parathyroid hormone (PTH) is the chief regulator of renal calcium reabsorption. This review outlines our current understanding of PTH's effects on renal tubular calcium transport, focusing on the more recent discoveries beyond its direct regulation of epithelial Ca channel transient receptor potential vanilloid 5 (TRPV5) and looking at its interaction with sodium transport and the hormones fibroblast growth factor 23 (FGF23) and klotho...
June 12, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28609763/calcium-sensing-receptor-genetic-polymorphisms-and-risk-of-developing-nephrolithiasis-in-a-chinese-population
#11
Qi Ding, Bo Fan, Ying Shi, Zhijiang Fan, Li Ding, Feng Li, Wenjian Tu, Xiaohua Jin, Chao Qin, Qiang Cao, Qinbo Yuan, Jing Wang, Jun Ouyang
OBJECTIVE: To evaluate the association between calcium-sensing receptor (CaSR) Arg990Gly (rs1042636, A > G), Ala986Ser (rs1801725, G > T) polymorphisms, and urolithiasis risk. METHODS: Polymorphisms mentioned above were genotyped in a hospital-based case-control study of 615 patients diagnosed with nephrolithiasis and 315 kidney stone-free controls in a Chinese population using the SNaPshot method. RESULTS: The results indicated a significantly increased risk associated with CaSR Arg990Gly GG genotypes (OR 1...
June 14, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28608191/shockwave-lithotripsy-techniques-for-improving-outcomes
#12
Tadeusz Kroczak, Kymora B Scotland, Ben Chew, Kenneth T Pace
OBJECTIVES: Shock wave lithotripsy (SWL) remains the only effective truly non-invasive treatment for nephrolithiasis. While single-treatment success rates may not equal those of ureteroscopy and percutaneous nephrolithotomy, it has an important role to play in the management of stones. In this paper, we outline the latest evidence-based recommendations for maximizing SWL outcomes, while minimizing complications. MATERIALS AND METHODS: A comprehensive review of the current literature was performed regarding maximizing SWL outcomes...
June 12, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28607877/recurrent-kidney-stone-episodes-leading-to-a-diagnosis-of-occult-acromegaly
#13
Julie N Thai, Timothy Y Tran, Oksana Davydov, Mantu Gupta
The association between nephrolithiasis and acromegaly has been previously described. Although the mechanism has been established, the urological literature sparsely discusses clinically suspecting that patients with recurrent nephrolithiasis could have acromegaly and subsequently referring them for accurate diagnosis and treatment. We present a case of occult acromegaly secondary to a pituitary tumor discovered 20 years after the patient's first stone episode.
September 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28605936/vascular-disease-and-kidney-stones-abdominal-aortic-calcifications-are-associated-with-low-urine-ph-and-hypocitraturia
#14
Nishant D Patel, Ryan D Ward, Juan Camilo Calle, Eric Remer, Manoj Monga
OBJECTIVE: Vascular calcifications are associated with nephrolithiasis. While studies have demonstrated correlations with vascular disease and calcium stones in kidney stone formers (KSF), an etiologic link has remained elusive. As a non-contrast CT scan (NCCT) is typically part of a stone evaluation, our objective was to evaluate the association of NCCT-based assessment of abdominal aortic calcifications (AAC) with 24-hour urine parameters and stone composition. MATERIALS AND METHODS: 97 KSF were included with CT imaging and 24-hour urine studies...
June 12, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28599030/pediatric-nephrolithiasis-a-review
#15
Tayaba Miah, Deepak Kamat
The incidence of pediatric nephrolithiasis is on the rise. The composition of kidney stones in children is different than in adults, as most stones in children have a composition of calcium oxalate and calcium phosphate mixed with a small amount of uric acid. The symptoms of pediatric nephrolithiasis are nonspecific. Computed tomography (CT) is the gold standard for diagnosis; however, because of radiation exposure associated with a CT scan, ultrasonography is also an accepted modality for the diagnosis. Extensive metabolic evaluation is important to rule out an underlying metabolic disorder...
June 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28597355/minimal-device-encrustation-on-vesair-intravesical-balloons-in-the-treatment-of-stress-urinary-incontinence-analysis-of-balloons-removed-from-women-in-the-solect-trial
#16
Gommert A van Koeveringe, Stefan De Wachter, Jack M Zuckerman, Giovanni Tommaselli, Michel J de Wildt, Karel C M Everaert, Dirk P J Michielsen, Jean-Jacques Wyndaele
INTRODUCTION: Encrustation of urinary biomaterials is common; however, the incidence of surface deposition on the Vesair(®) intravesical pressure-attenuation balloon has not been previously reported. The purpose of this analysis is to determine the incidence and potential risk factors for encrustation of the Vesair intravesical balloon. METHODS: The SOLECT trial is a prospective randomized controlled trial conducted at several European centers to evaluate the safety and efficacy of the Vesair balloon for the treatment of female stress urinary incontinence (SUI)...
June 9, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28592419/serum-uric-acid-levels-and-multiple-health-outcomes-umbrella-review-of-evidence-from-observational-studies-randomised-controlled-trials-and-mendelian-randomisation-studies
#17
REVIEW
Xue Li, Xiangrui Meng, Maria Timofeeva, Ioanna Tzoulaki, Konstantinos K Tsilidis, P A Ioannidis, Harry Campbell, Evropi Theodoratou
Objective To map the diverse health outcomes associated with serum uric acid (SUA) levels.Design Umbrella review.Data sources Medline, Embase, Cochrane Database of Systematic Reviews, and screening of citations and references.Eligibility criteria Systematic reviews and meta-analyses of observational studies that examined associations between SUA level and health outcomes, meta-analyses of randomised controlled trials that investigated health outcomes related to SUA lowering treatment, and Mendelian randomisation studies that explored the causal associations of SUA level with health outcomes...
June 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28588843/bilateral-hydronephrosis-due-to-obstructive-ureteral-stone-associated-with-norovirus-gastroenteritis
#18
Fumihiro Ochi, Kenji Furuno, Pin Fee Chong, Junichiro Tezuka, Yumi Mizuno, Tomonobu Aoki, Eiichi Ishii
Recently, cases of urinary tract calculi causing hydronephrosis and postrenal renal failure associated with viral gastroenteritis were documented, yet few were related to norovirus. During norovirus gastroenteritis, observation of oliguria, aciduria, low FENa value, and elevation of blood or urinary uric acid level may necessitate clinical workout for nephrolithiasis.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28587918/ct-based-diagnosis-of-visceral-obesity-and-hepatic-steatosis-is-associated-with-low-urine-ph
#19
Nishant D Patel, Ryan D Ward, Juan Calle, Erick M Remer, Manoj Monga
PURPOSE: Uric acid nephrolithiasis is associated with elevated visceral fat area (VFA) in kidney stone formers (KSF). Hepatic steatosis has also been linked to visceral obesity and nephrolithiasis. We evaluated the association of NCCT-based diagnosis of visceral obesity and hepatic steatosis with 24-hour urine parameters and stone composition in KSF. MATERIAL AND METHODS: 98 KSF were included who had CT imaging and 24-hour urine studies. For each patient, a single CT axial area measurement was obtained for visceral fat area (VFA)...
June 3, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28584844/castleman-disease-presenting-as-an-abdominal-mass
#20
Farnaz Shariati, Elizabeth Verter, Wendy Chang, Li Huang, Virendra Joshi
Unicentric Castleman disease is a rare condition of lymphoid hyperplasia, of which only 15% of cases occur in the abdomen. We report a 66-year-old man who presented with complaints of abdominal pain. Computed tomography scans revealed nephrolithiasis and a homogeneous calcified mass between the pancreas and stomach and several para-pancreatic nodes. Direct visualization during exploratory laparotomy revealed a mass on the lesser curvature of the stomach. Pyloromyotomy and mass resection were performed. Biopsy showed reactive lymphoid hyperplasia consistent with the hyaline vascular variant of Castleman disease...
2017: ACG Case Reports Journal
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