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1950: Acta Pharmacologica et Toxicologica
Jianxin Zhao, Huazhou Xu, Yuanxiang Tian, Manxiang Hu, Hongling Xiao
OBJECTIVE: This work aims to observe the effects of electroacupuncture on brain-derived neurotrophic factor (BDNF) mRNA expression in mouse hippocampus following cerebral ischemia-reperfusion injury. METHODS: The models of mouse cerebral ischemia-reperfusion injury were established. A total of 96 healthy mice were randomly assigned into 4 groups, namely, the sham surgery, model, model + electroacupuncture, and mode + hydergine groups. Mice in the model + electroacupuncture group were treated through electroacupuncture at the Shenshu (BL 23), Geshu (BL 17), and Baihui (GV 20) acupoints...
April 2013: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
Jian-Xin Zhao, Yuan-Xiang Tian, Hong-Ling Xiao, Man-Xiang Hu, Wei-Ran Chen
OBJECTIVE: To observe the effects of electroacupuncture on hippocampal and cortical apoptosis in a mouse model of cerebral ischemia-reperfusion injury. METHODS: Mouse models established by repeated cerebral ischemia-reperfusion, followed by electroacupuncture at Shenshu, Geshu, and Baihui points. The control group mice were intragastrically administered Hydergine. On day 1 and 7 post-treatment, hippocampal and cortical apoptosis was detected by terminal-deoxynucleotidyl transferase mediated dUTP nick-end labeling (TUNEL), and apoptosis images in the hippocampal CA1 zone and cortical area were analyzed...
December 2011: Journal of Traditional Chinese Medicine, Chung i Tsa Chih Ying Wen Pan
S G Chaney, M R Kare
Comparative studies of emesis in the herring gull, pigeon, chicken, and cowbird were conducted, using orally administered copper sulfate and intravenously administered copper sulfate, hydergine, apomorphine, and lanatoside C. A response to every emetic was elicited from some birds. However, the individual and species differences among the birds were as great as those among mammals. Further, the response of the avian species studied did not indicate that any of them could be used to predict how a specific mammal would react...
October 1, 1966: Journal of the American Veterinary Medical Association
R Bechter, H Schön
The embryotoxicity and, in particular, the teratogenic potential of three new drug combinations were investigated. The interactions of the single components (all already on the market) in the different drug mixtures were determined by testing the single components in addition to the drug combinations. In order to evaluate the usefulness of these results for safety assessment, the no-effect concentrations (NEC) of the single compounds or the mixed drug preparations, with respect to embryonic growth and differentiation and the presence of anomalies, were compared with human plasma/serum levels during therapeutic use...
1988: Toxicology in Vitro: An International Journal Published in Association with BIBRA
L J Berry, D S Smythe
In vitro secretion of glycocorticoids by adrenal glands pooled from several control mice was compared with that of glands removed from animals following injections of either ACTH or endotoxin. Both substances prevent glycocorticoid synthesis stimulated in vitro with ACTH. Cholesterol content of adrenal glands under these conditions was nearly depleted, indicating maximal response to ACTH or endotoxin prior to their removal for the in vitro tests. In an effort to account physiologically for the manner in which endotoxin suppresses or prevents the rise in urinary nitrogen excreted in response to ACTH, blood non-protein nitrogen levels (NPN) were determined...
October 31, 1961: Journal of Experimental Medicine
Andrius Baskys, Anthony C Hou
Vascular dementia is a common condition for which there are no effective approved pharmacological treatments available. Absence of effective treatments creates a difficult situation for those suffering from the disease, their caregivers, and healthcare providers. This review will address our current understanding of the mechanisms of nerve cell damage due to ischemia and summarize available clinical trial data on several commonly used compounds including memantine, donepezil, galantamine, rivastigmine, nimodipine, hydergine, nicergoline, CDP-choline, folic acid, as well as such nonpharmacological approaches as validation therapy...
2007: Clinical Interventions in Aging
G Barrier
No abstract text is available yet for this article.
November 1973: Revue Française de Gynécologie et D'obstétrique
Jing Cai, Jian Du, Zhen-hua Ge, Fan Zhou, Lin-yin Zhou, Lian-yun Chen
OBJECTIVE: To observe the effect of Kangxin Capsule (KXC) on the expression of nerve growth factor (NGF) as well as the morphology and amount of nerve synapse in the cortical parietal lobe and hippocampus CA, area of vascular dementia ( VD) model rats. METHODS: The model rats of VD made by photochemical reaction technique were randomly divided into five groups: the model group (MG), the high-dose, middle-dose and low-dose KXC groups (HDG, MDG and LDG), and the Western medicine hydergin control group (WMG)...
December 2006: Chinese Journal of Integrative Medicine
Ursula Werneke, Trevor Turner, Stefan Priebe
BACKGROUND: The use of complementary medicines in those with mental health problems is well documented. However, their effectiveness is often not established and they may be less harmless than commonly assumed. AIMS: To review the complementary medicines routinely encountered in psychiatric practice, their effectiveness, potential adverse effects and interactions. METHOD: Electronic and manual literature search on the effectiveness and safety of psychotropic complementary medicines...
February 2006: British Journal of Psychiatry: the Journal of Mental Science
Steven Shoptaw, Donnie W Watson, Chris Reiber, Richard A Rawson, Margaret A Montgomery, Maria D Majewska, Walter Ling
AIM: This study tested three dopaminergic medications against a common unmatched placebo condition: hydergine 1 mg three times daily (n = 15); levodopa/carbidopa 25/100 mg three times daily (n = 15); cabergoline 0.5 mg per week (n = 15); and placebo three times daily (n = 15) as potential pharmacotherapies for cocaine dependence. DESIGN: The four-parallel group, Cocaine Rapid Efficacy Screening Trial (CREST) design featured a 2-week baseline period followed by randomization to an 8-week medication condition that included 1 hour per week of cognitive behavioral drug counseling...
March 2005: Addiction
No abstract text is available yet for this article.
October 1954: Anesthésie et Analgésie
No abstract text is available yet for this article.
April 1950: Revista Médica de Chile
No abstract text is available yet for this article.
July 1950: Ophthalmologica. Journal International D'ophtalmologie
No abstract text is available yet for this article.
May 1, 1950: Klinische Wochenschrift
No abstract text is available yet for this article.
1950: Schweizer Archiv Für Neurologie und Psychiatrie. Archives Suisses de Neurologie et de Psychiatrie
No abstract text is available yet for this article.
May 1950: Helvetica Paediatrica Acta
No abstract text is available yet for this article.
1950: Cardiologia
No abstract text is available yet for this article.
May 15, 1950: Archives Internationales de Pharmacodynamie et de Thérapie
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