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https://www.readbyqxmd.com/read/28636455/the-role-of-the-healthcare-chaplain-a-literature-review
#1
Fiona Timmins, Sílvia Caldeira, Maryanne Murphy, Nicolas Pujol, Greg Sheaf, Elizabeth Weathers, Jacqueline Whelan, Bernadette Flanagan
Healthcare chaplains operate in many healthcare sites internationally and yet their contribution is not always clearly understood by medical and healthcare staff. This review aims to explore the chaplains' role in healthcare, with a view to informing best practice in future healthcare chaplaincy. Overall the extent of the provision and staffing of chaplaincy service internationally is unclear. From this review, several key spiritual and pastoral roles in healthcare emerge including a potential contribution to ethical decision making at the end of life...
June 21, 2017: Journal of Health Care Chaplaincy
https://www.readbyqxmd.com/read/28628581/a-collaborative-approach-to-childhood-obesity-surveillance-from-a-local-health-department
#2
Elizabeth Alleman, Elizabeth Murphy, Kristin Baskerville, Rashmi Chugh
DuPage County Health Department collected de-identified data from health forms submitted by participating schools for academic years 2011-2015 for kindergarten, sixth-, and ninth-grade students to determine the prevalence of obesity and elevated blood pressure among public school students. The prevalence of obesity in students for the 2014-2015 school year was 15.1%, and the prevalence of elevated blood pressure was 22.8%. Students in the "obese" body mass index percentile category had an elevated blood pressure prevalence of 44...
June 16, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28618885/an-exploration-of-current-approaches-to-and-facilities-for-spiritual-care-provision-in-the-republic-of-ireland
#3
Fiona Timmins, Sílvia Caldeira, Maryanne Murphy, Nicolas Pujol, Greg Sheaf, Elizabeth Weathers, Jacqueline Whelan, Bernadette Flanagan
This study aimed to explore current approaches to and facilities for spiritual care provision in the Republic of Ireland. The findings identify that providing spiritual care to patients is a key component of hospital policy. Spiritual support is identified as the responsibility of the whole healthcare team with specific responsibility being attributed to the healthcare chaplain. Most sites provided a sacred space or quiet place for clients, visitors and staff to contemplate.
June 2017: Journal of Pastoral Care & Counseling: JPCC
https://www.readbyqxmd.com/read/28614974/electronic-consultation-system-demonstrates-educational-benefit-for-primary-care-providers
#4
Jonas Kwok, J Nwando Olayiwola, Margae Knox, Elizabeth J Murphy, Delphine S Tuot
Background Electronic consultation systems allow primary care providers to receive timely speciality expertise via iterative electronic communication. The use of such systems is expanding across the USA with well-documented high levels of user satisfaction. We characterise the educational impact for primary care providers of a long-standing integrated electronic consultation and referral system. Methods Primary care providers' perceptions of the educational value inherent to electronic consultation system communication and the impact on their ability to manage common speciality clinical conditions and questions were examined by electronic survey using five-point Likert scales...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28580655/a-quantitative-assay-for-amaranthus-palmeri-identification
#5
Brent P Murphy, Diane E Plewa, Elizabeth Phillippi, Suzanne M Bissonnette, Patrick J Tranel
BACKGROUND: Amaranthus palmeri recently has been brought into the Midwestern U.S. as a contaminant in Conservation Reserve Program (CRP) seeding mixes. Rapid species screening is required to mitigate the risk of continued species movement. RESULTS: Markers were developed for A. palmeri-specific nucleotide polymorphisms in the internal transcribed spacer of the ribosomal coding region. A quantitative PCR (qPCR) assay successfully identified A. palmeri from single-plants, simulated mixed-plant samples, and seed mixtures...
June 5, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28575757/sensorimotor-experience-and-verb-category-mapping-in-human-sensory-motor-and-parietal-neurons
#6
Ying Yang, Michael Walsh Dickey, Julie Fiez, Brian Murphy, Tom Mitchell, Jennifer Collinger, Elizabeth Tyler-Kabara, Michael Boninger, Wei Wang
Semantic grounding is the process of relating meaning to symbols (e.g., words). It is the foundation for creating a representational symbolic system such as language. Semantic grounding for verb meaning is hypothesized to be achieved through two mechanisms: sensorimotor mapping, i.e., directly encoding the sensorimotor experiences the verb describes, and verb-category mapping, i.e., encoding the abstract category a verb belongs to. These two mechanisms were investigated by examining neuronal-level spike (i...
May 6, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28554910/supportive-text-messages-for-patients-with-alcohol-use-disorder-and-a-comorbid-depression-a-protocol-for-a-single-blind-randomised-controlled-aftercare-trial
#7
Dan Hartnett, Edel Murphy, Elizabeth Kehoe, Vincent Agyapong, Declan M McLoughlin, Conor Farren
INTRODUCTION: Alcohol use disorders (AUDs) and mood disorders commonly co-occur, and are associated with a range of negative outcomes for patients. Mobile phone technology has the potential to provide personalised support for such patients and potentially improve outcomes in this difficult-to-treat cohort. The aim of this study is to examine whether receiving supporting SMS text messages, following discharge from an inpatient dual diagnosis treatment programme, has a positive impact on mood and alcohol abstinence in patients with an AUD and a comorbid mood disorder...
May 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28553879/the-relationship-between-lower-body-stiffness-and-injury-incidence-in-female-netballers
#8
Elizabeth C Pickering Rodriguez, Mark L Watsford, Rob G Bower, Aron J Murphy
The aim of this study was to provide contemporary information on injury rates in an elite and sub-elite netball population and to explore the relationship between lower body stiffness and lower body injuries. One elite and two sub-elite teams of female netballers (n = 29) performed the vertical hop test to assess active lower body stiffness (Kvert) and myometry to assess quasi-static stiffness. Lower body injuries were monitored via self-reporting and liaison with physiotherapists. Twelve lower body non-contact injuries were sustained by 10 players, equating to 11...
May 29, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28551781/the-in-vivo-biology-of-the-mitochondrial-calcium-uniporter
#9
Julia C Liu, Randi J Parks, Jie Liu, Justin Stares, Ilsa I Rovira, Elizabeth Murphy, Toren Finkel
The identification of the molecular composition of the mitochondrial calcium uniporter has allowed for the genetic manipulation of its components and the creation of various in vivo genetic models. Here, we review the initial attempts to modulate the expression of components of the calcium uniporter in a range of organisms from plants to mammals. This analysis has confirmed the strict requirement for the uniporter for in vivo mitochondrial calcium uptake and for maintaining mitochondrial calcium homeostasis...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28546494/draft-genome-sequence-of-acidihalobacter-ferrooxidans-dsm-14175-strain-v8-a-new-iron-and-sulfur-oxidizing-halotolerant-acidophilic-species
#10
Himel N Khaleque, Joshua P Ramsay, Riley J T Murphy, Anna H Kaksonen, Naomi J Boxall, Elizabeth L J Watkin
The use of halotolerant acidophiles for bioleaching provides a biotechnical approach for the extraction of metals from regions where high salinity exists in the ores and source water. Here, we describe the first draft genome of a new species of a halotolerant and iron- and sulfur-oxidizing acidophile, Acidihalobacter ferrooxidans DSM 14175 (strain V8).
May 25, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28526844/identification-of-extracellular-glycerophosphodiesterases-in-pseudomonas-and-their-role-in-soil-organic-phosphorus-remineralisation
#11
Ian D E A Lidbury, Andrew R J Murphy, Tandra D Fraser, Gary D Bending, Alexandra M E Jones, Jonathan D Moore, Andrew Goodall, Mark Tibbett, John P Hammond, David J Scanlan, Elizabeth M H Wellington
In soils, phosphorus (P) exists in numerous organic and inorganic forms. However, plants can only acquire inorganic orthophosphate (Pi), meaning global crop production is frequently limited by P availability. To overcome this problem, rock phosphate fertilisers are heavily applied, often with negative environmental and socio-economic consequences. The organic P fraction of soil contains phospholipids that are rapidly degraded resulting in the release of bioavailable Pi. However, the mechanisms behind this process remain unknown...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28522833/parkin-regulation-of-chop-modulates-susceptibility-to-cardiac-endoplasmic-reticulum-stress
#12
Kim Han, Shahin Hassanzadeh, Komudi Singh, Sara Menazza, Tiffany T Nguyen, Mark V Stevens, An Nguyen, Hong San, Stasia A Anderson, Yongshun Lin, Jizhong Zou, Elizabeth Murphy, Michael N Sack
The regulatory control of cardiac endoplasmic reticulum (ER) stress is incompletely characterized. As ER stress signaling upregulates the E3-ubiquitin ligase Parkin, we investigated the role of Parkin in cardiac ER stress. Parkin knockout mice exposed to aortic constriction-induced cardiac pressure-overload or in response to systemic tunicamycin (TM) developed adverse ventricular remodeling with excessive levels of the ER regulatory C/EBP homologous protein CHOP. CHOP was identified as a Parkin substrate and its turnover was Parkin-dose and proteasome-dependent...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28509721/bundled-payments-for-care-improvement-preparing-for-the-medical-diagnosis-related-groups
#13
Lauran Hardin, Adam Kilian, Elizabeth Murphy
BACKGROUND: The Centers for Medicare and Medicaid Services Innovation Center introduced the Bundled Payments for Care Improvement (BPCI) initiative in 2011 as 1 strategy to encourage healthcare organizations and clinicians to improve healthcare delivery for patients, both when they are in the hospital and after they are discharged. Mercy Health Saint Mary's, a large urban academic medical center, engaged in BPCI primarily with a group of medical diagnosis-related groups (DRGs). OBJECTIVES: In this article, we describe our experience creating a system of response for the diverse people and diagnoses that fall into the medical DRG bundles and specifically identify organizational factors for enabling successful implementation of bundled payments...
June 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28504062/the-health-promoting-schools-framework-known-unknowns-and-an-agenda-for-future-research
#14
Rebecca Langford, Christopher Bonell, Kelli Komro, Simon Murphy, Daniel Magnus, Elizabeth Waters, Lisa Gibbs, Rona Campbell
The World Health Organization's Health Promoting Schools (HPS) framework is a whole-school approach to promoting health that recognizes the intrinsic relationship between health and education. Our recent Cochrane systematic review found HPS interventions produced improvements in a number of student health outcomes. Here we reflect on what this review was not able to tell us: in other words, what evidence is missing with regard to the HPS approach. Few HPS interventions engage with schools' "core business" by examining impacts on educational outcomes...
June 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28498658/discovery-of-clinical-candidate-1-2s-3s-4s-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl-methoxy-7-methoxyisoquinoline-6-carboxamide-pf-06650833-a-potent-selective-inhibitor-of-interleukin-1-receptor-associated-kinase-4-irak4-by-fragment-based-drug-design
#15
Katherine L Lee, Catherine M Ambler, David R Anderson, Brian P Boscoe, Andrea G Bree, Joanne I Brodfuehrer, Jeanne S Chang, Chulho Choi, Seungwon Chung, Kevin J Curran, Jacqueline E Day, Christoph M Dehnhardt, Ken Dower, Susan E Drozda, Richard K Frisbie, Lori K Gavrin, Joel A Goldberg, Seungil Han, Martin Hegen, David Hepworth, Heidi R Hope, Satwik Kamtekar, Iain C Kilty, Arthur Lee, Lih-Ling Lin, Frank E Lovering, Michael D Lowe, John P Mathias, Heidi M Morgan, Elizabeth A Murphy, Nikolaos Papaioannou, Akshay Patny, Betsy S Pierce, Vikram R Rao, Eddine Saiah, Ivan J Samardjiev, Brian M Samas, Marina W H Shen, Julia H Shin, Holly H Soutter, Joseph W Strohbach, Peter T Symanowicz, Jennifer R Thomason, John D Trzupek, Richard Vargas, Fabien Vincent, Jiangli Yan, Christoph W Zapf, Stephen W Wright
Through fragment-based drug design focused on engaging the active site of IRAK4 and leveraging three-dimensional topology in a ligand-efficient manner, a micromolar hit identified from a screen of a Pfizer fragment library was optimized to afford IRAK4 inhibitors with nanomolar potency in cellular assays. The medicinal chemistry effort featured the judicious placement of lipophilicity, informed by co-crystal structures with IRAK4 and optimization of ADME properties to deliver clinical candidate PF-06650833 (compound 40)...
June 14, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28493997/adenosine-a1-receptor-activation-increases-myocardial-protein-s-nitrosothiols-and-elicits-protection-from-ischemia-reperfusion-injury-in-male-and-female-hearts
#16
Qin Shao, Kevin M Casin, Nathan Mackowski, Elizabeth Murphy, Charles Steenbergen, Mark J Kohr
Nitric oxide (NO) plays an important role in cardioprotection, and recent work from our group and others has implicated protein S-nitrosylation (SNO) as a critical component of NO-mediated protection in different models, including ischemic pre- and post-conditioning and sex-dependent cardioprotection. However, studies have yet to examine whether protein SNO levels are similarly increased with pharmacologic preconditioning in male and female hearts, and whether an increase in protein SNO levels, which is protective in male hearts, is sufficient to increase baseline protection in female hearts...
2017: PloS One
https://www.readbyqxmd.com/read/28486638/predictors-of-discharge-to-a-nonhome-facility-in-patients-undergoing-lumbar-decompression-without-fusion-for-degenerative-spine-disease
#17
Meghan E Murphy, Patrick R Maloney, Brandon A McCutcheon, Lorenzo Rinaldo, Daniel Shepherd, Panagiotis Kerezoudis, Hannah Gilder, Daniel S Ubl, Cynthia S Crowson, Brett A Freedman, Elizabeth B Habermann, Mohamad Bydon
BACKGROUND: Patients recovering from decompressive laminectomy without fusion may require assistance with activities of daily living and physical/occupational therapy upon hospital discharge. OBJECTIVE: To examine comorbidities and perioperative characteristics of patients undergoing lumbar decompression for associations with discharge status using a multicenter database. METHODS: A multicenter database was used for this retrospective cohort analysis...
May 9, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28484921/preoperative-prediction-of-node-negative-disease-after-neoadjuvant-chemotherapy-in-patients-presenting-with-node-negative-or-node-positive-breast-cancer
#18
Brittany L Murphy, Tanya L Hoskin, Courtney Day N Heins, Elizabeth B Habermann, Judy C Boughey
BACKGROUND: Axillary node status after neoadjuvant chemotherapy (NAC) influences the axillary surgical staging procedure as well as recommendations regarding reconstruction and radiation. OBJECTIVE: Our aim was to construct a clinical preoperative prediction model to identify the likelihood of patients being node negative after NAC. METHODS: Using the National Cancer Database (NCDB) from January 2010 to December 2012, we identified cT1-T4c, N0-N3 breast cancer patients treated with NAC...
May 8, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28476168/dioxins-and-related-environmental-contaminants-increase-tdp-43-levels
#19
Peter E A Ash, Elizabeth A Stanford, Ali Al Abdulatif, Alejandra Ramirez-Cardenas, Heather I Ballance, Samantha Boudeau, Amanda Jeh, James M Murithi, Yorghos Tripodis, George J Murphy, David H Sherr, Benjamin Wolozin
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative condition that is characterized by progressive loss of motor neurons and the accumulation of aggregated TAR DNA Binding Protein-43 (TDP-43, gene: TARDBP). Increasing evidence indicates that environmental factors contribute to the risk of ALS. Dioxins, related planar polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that activate the aryl hydrocarbon receptor (AHR), a ligand-activated, PAS family transcription factor...
May 5, 2017: Molecular Neurodegeneration
https://www.readbyqxmd.com/read/28466761/can-targeted-job-information-for-adults-with-spinal-cord-dysfunction-be-effectively-delivered-online-a-pilot-study
#20
Diana Dorstyn, Rachel Roberts, Gregory Murphy, Ian Kneebone, Ashley Craig, Anna Chur-Hansen, Christine Migliorini, Elizabeth Potter, Ruth Marshall, Jillian Clark, Sharron Neeson, Peter Stewart
OBJECTIVE: To pilot a novel email-based information package (Work and SCI) for job-seekers with an acquired spinal cord injury (SCI) or spinal cord dysfunction (SCI/D). STUDY DESIGN: Prospective, non-randomized, repeated measures trial. SETTING: Community dwelling cohort in Australia. PARTICIPANTS: Five people with SCI (mean age 46.4 years, SD = 10.2; 4 female) initially reviewed Work and SCI. Twenty-four with SCI/D subsequently enrolled, of whom 16 (mean age 46...
May 3, 2017: Journal of Spinal Cord Medicine
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