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Keywords Gluten, pineal,

Gluten, pineal,

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JOURNAL ARTICLE

Growth hormone impaired secretion and antipituitary antibodies in patients with coeliac disease and poor catch-up growth after a long gluten-free diet period: a causal association?

Lorenzo Iughetti, Annamaria De Bellis, Barbara Predieri, Antonio Bizzarro, Michele De Simone, Fiorella Balli, Antonio Bellastella, Sergio Bernasconi

INTRODUCTION: Coeliac disease (CD) is usually associated with impaired growth in children. A gluten-free diet (GFD) induces a catch-up growth with the recovery of height in about 2 years. AIM AND DISCUSSION: The lack of the height improvement has been related to growth hormone (GH) secretion impairment. CD is an autoimmune disease often associated with other endocrine and non-endocrine autoimmune disease. The aim of this study was to evaluate antipituitary autoantibodies (APA) and antihypothalamus autoantibodies in CD children with poor clinical response to a GFD and growth hormone deficiency (GHD)...

16896648

December 2006: European Journal of Pediatrics

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