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https://www.readbyqxmd.com/read/16896648/growth-hormone-impaired-secretion-and-antipituitary-antibodies-in-patients-with-coeliac-disease-and-poor-catch-up-growth-after-a-long-gluten-free-diet-period-a-causal-association
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Lorenzo Iughetti, Annamaria De Bellis, Barbara Predieri, Antonio Bizzarro, Michele De Simone, Fiorella Balli, Antonio Bellastella, Sergio Bernasconi
INTRODUCTION: Coeliac disease (CD) is usually associated with impaired growth in children. A gluten-free diet (GFD) induces a catch-up growth with the recovery of height in about 2 years. AIM AND DISCUSSION: The lack of the height improvement has been related to growth hormone (GH) secretion impairment. CD is an autoimmune disease often associated with other endocrine and non-endocrine autoimmune disease. The aim of this study was to evaluate antipituitary autoantibodies (APA) and antihypothalamus autoantibodies in CD children with poor clinical response to a GFD and growth hormone deficiency (GHD)...
December 2006: European Journal of Pediatrics
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