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Integrative psychiatry

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https://www.readbyqxmd.com/read/29741616/a-systematic-review-of-genome-wide-research-on-psychotic-experiences-and-negative-symptom-traits-new-revelations-and-implications-for-psychiatry
#1
Angelica Ronald, Oliver Pain
We present a systematic review of genome-wide research on psychotic experience and negative symptom traits (PENS) in the community. We integrate these new findings, most of which have emerged over the last four years, with more established behaviour genetic and epidemiological research. The review includes the first genome-wide association studies of PENS, including a recent meta-analysis, and the first SNP heritability estimates. Sample sizes of < 10,000 participants mean that no genome-wide significant variants have yet been replicated...
May 8, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29739522/a-psychodynamic-approach-for-the-general-psychiatrist-using-transference-focused-psychotherapy-principles-in-acute-care-settings
#2
REVIEW
Richard G Hersh
Transference-focused psychotherapy (TFP) is one of the empirically validated treatments for patients with borderline personality disorder. TFP has roots in psychoanalytically informed psychotherapy, although important elements of the treatment have been adapted and refined for patients with significant personality disorder pathology. TFP's assessment process is informed by the structural interview, an approach that synthesizes standard DSM-5 nosology with the psychodynamic concept of the personality organization...
June 2018: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29739518/on-the-birth-of-psychodynamic-psychiatry
#3
REVIEW
Richard C Friedman, Jennifer I Downey, César A Alfonso
Psychodynamic psychiatry emerged from psychoanalytic theory, but the influence of the latter has been only partial. Equally important are other disciplines outlined within is article. Modern psychodynamic publications and presentations should honor all of the foundational pillars of the field. In this way, the new area lends itself to bio-psycho-social integrations that remain a challenge for all researchers and clinicians who seek to understand and treat patients with mental disorders.
June 2018: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29734057/institutionalised-otherness-patients-references-to-psychiatric-diagnostic-categories
#4
Elina Weiste, Anssi Peräkylä, Taina Valkeapää, Enikö Savander, Jukka Hintikka
Diagnosis is integral part of the way medicine organises illness: it is important for identifying treatment options, predicting outcomes and providing an explanatory framework for clinicians. Previous research has shown that during a medical visit not only the clinician but also patients provide explanations for the causes of their symptoms and health problems. Patients' lifeworld explanations are often differentiated from the diagnostic explanations provided by clinicians. However, while previous conversation analytic research has elaborated the ways in which diagnostic and lifeworld explanations are interactionally structured in somatic medicine, there is little research on how these explanations are organised in psychiatry...
April 30, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29730941/emotional-reactivity-to-daily-events-in-youth-with-anxiety-disorders
#5
Joanna Herres, Nicole E Caporino, Colleen M Cummings, Philip C Kendall
BACKGROUND: Although research supports associations between anxiety and emotional reactivity in adults (Cisler, J. M., Olatunji, B. O., Feldner, M. T., & Forsyth, J. P. (2010). Emotion regulation and the anxiety disorders: an integrative review. Journal of Psychopathology and Behavioral Assessment, 32(1), 68-82.), few studies have examined emotional reactivity in anxious youth (e.g., Carthy et al., 2010; Tan, P. Z., Forbes, E. E., Dahl, R. E., Ryan, N. D., Siegle, G. J...
May 7, 2018: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/29719288/the-hypothalamic-pituitary-adrenal-axis-a-brief-history
#6
Walter L Miller
The hypothalamic-pituitary-adrenal (HPA) axis is central to homeostasis, stress responses, energy metabolism, and neuropsychiatric function. The history of this complex system involves discovery of the relevant glands (adrenal, pituitary, hypothalamus), hormones (cortisol, corticotropin, corticotropin-releasing hormone), and the receptors for these hormones. The adrenal and pituitary were identified by classical anatomists, but most of this history has taken place rather recently, and has involved complex chemistry, biochemistry, genetics, and clinical investigation...
May 2, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/29710118/disorganized-gyrification-network-properties-during-the-transition-to-psychosis
#7
Tushar Das, Stefan Borgwardt, Daniel J Hauke, Fabienne Harrisberger, Undine E Lang, Anita Riecher-Rössler, Lena Palaniyappan, André Schmidt
Importance: There is urgent need to improve the limited prognostic accuracy of clinical instruments to predict psychosis onset in individuals at clinical high risk (CHR) for psychosis. As yet, no reliable biological marker has been established to delineate CHR individuals who will develop psychosis from those who will not. Objectives: To investigate abnormalities in a graph-based gyrification connectome in the early stages of psychosis and to test the accuracy of this systems-based approach to predict a transition to psychosis among CHR individuals...
April 25, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29697521/an-integrative-review-of-nurse-authored-research-to-improve-health-equity-and-human-rights-for-criminal-justice-involved-people
#8
Lorie S Goshin, Alison M Colbert, John F Carey
BACKGROUND: An estimated 10 million people are incarcerated internationally, including 2.1 million people in the United States. Criminal justice involvement is a social determinant of individual and family health disparities. Health care in correctional and forensic psychiatric facilities is nurse driven. The unique contributions of nurse authors to the research literature on health equity and humane conditions for this population have not been aggregated, nor have the nursing research gaps in this area been systematically identified...
April 24, 2018: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/29691958/brain-based-treatment-a-new-approach-or-a-well-forgotten-old-one
#9
Vanya Matanova, Zlatomira Kostova, Martin Kolev
For a relatively long period of time, mental functioning was mainly associated with personal profile while brain functioning went by the wayside. After the 90s of the 20th century, or the so called "Decade of the Brain", today, contemporary specialists work on the boundary between fundamental science and medicine. This brings neuroscience, neuropsychology, psychiatry, and psychotherapy closer to each other. Today, we definitely know that brain structures are being built and altered thanks to experience...
April 24, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29687938/trait-and-state-biomarkers-for-psychiatric-disorders-importance-of-infrastructure-to-bridge-the-gap-between-basic-and-clinical-research-and-industry
#10
Yukiko Y Lema, Nao J Gamo, Kun Yang, Koko Ishizuka
To further improve clinical activities in psychiatry by early diagnosis and early intervention with novel mechanism-guided treatments, there is a great need for biomarkers that reflect "trait" and "state" in major mental disorders. Stable trait biomarkers would allow early diagnosis, prognosis, and hopefully early intervention in these disorders, while dynamic state markers that reflect symptomatic changes would help to develop treatments that target these molecular mechanisms. However, in the search for such biomarkers, and eventually translating them to the clinic and industry, challenges currently exist at multiple levels, from basic scientific understanding, patient sample collection, and sample and data management, to bridging the gap between basic and clinical research and industry...
April 24, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29674773/-problems-and-perspectives-in-psychiatric-diagnosis
#11
Angelo Picardi, Martina Valentini, Massimo Biondi
Diagnosis in psychiatry is a complex and difficult issue. A great many considerations have been made about the debatable ontological status of mental disorders and the difficulties in providing flawless definitions for them. While these considerations help appreciate the subtleties and difficulties of the topic, they do not imply that mental disorders do not exist or that nosological classification is unnecessary or useless. Although classifications have some inherent flaws and limitations, they can nevertheless be useful...
March 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29669557/discovery-biology-of-neuropsychiatric-syndromes-dbns-a-center-for-integrating-clinical-medicine-and-basic-science
#12
Biju Viswanath, Naren P Rao, Janardhanan C Narayanaswamy, Palanimuthu T Sivakumar, Arun Kandasamy, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, Ganesan Venkatasubramanian, John P John, Odity Mukherjee, Meera Purushottam, Ramakrishnan Kannan, Bhupesh Mehta, Thennarasu Kandavel, B Binukumar, Jitender Saini, Deepak Jayarajan, A Shyamsundar, Sydney Moirangthem, K G Vijay Kumar, Jagadisha Thirthalli, Prabha S Chandra, Bangalore N Gangadhar, Pratima Murthy, Mitradas M Panicker, Upinder S Bhalla, Sumantra Chattarji, Vivek Benegal, Mathew Varghese, Janardhan Y C Reddy, Padinjat Raghu, Mahendra Rao, Sanjeev Jain
BACKGROUND: There is emerging evidence that there are shared genetic, environmental and developmental risk factors in psychiatry, that cut across traditional diagnostic boundaries. With this background, the Discovery biology of neuropsychiatric syndromes (DBNS) proposes to recruit patients from five different syndromes (schizophrenia, bipolar disorder, obsessive compulsive disorder, Alzheimer's dementia and substance use disorders), identify those with multiple affected relatives, and invite these families to participate in this study...
April 18, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29665607/-who-benefits-from-forensic-psychiatric-treatment-results-of-a-catamnestic-study-in-swabia
#13
Manuela Dudeck, Irina Franke, Adelheid Bezzel, Stefanie Otte, Norbert Ormanns, Stefanie Nigel, Felix Segmiller, Judith Streb
OBJECTIVE: Evaluation of treatment outcomes of forensic inpatients in the Bavarian district of Swabia (2010 - 2014). METHODS: 130 inpatients were interviewed about their social reintegration, substance use and delinquency immediately after discharge from forensic psychiatry and one year after. RESULTS: One year after discharge 67 % of the patients referred due to substance use disorder according to § 64 of the German Penal Code were employed, 57 % were abstinent and 83 % did not reoffend...
April 17, 2018: Psychiatrische Praxis
https://www.readbyqxmd.com/read/29625949/optimizing-electronic-consultation-between-primary-care-providers-and-psychiatrists-mixed-methods-study
#14
Jennifer M Hensel, Rebecca Yang, Minnie Rai, Valerie H Taylor
BACKGROUND: The use of electronic consultation (e-consult) between primary care providers (PCPs) and psychiatrists has potential, given the high prevalence of mental health issues in primary care and problematic access to specialist care. Utilization and uptake, however, appears to be lower than would be expected. OBJECTIVE: This study aimed to examine actual utilization of e-consult between PCPs and psychiatrists and investigate the perceptions of PCPs about this form of psychiatric advice to inform how to optimize the utility and thereby the uptake of this service...
April 6, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29624652/religious-stigmata-a-dermato-psychiatric-approach-and-differential-diagnosis
#15
REVIEW
Elio Kechichian, Elie Khoury, Sami Richa, Roland Tomb
BACKGROUND: Stigma refers to the wounds reproduced on the human body, similar to the ones inflicted on the Christ during his crucifixion, on the palms, soles, and head, as well as the right or the left side of the chest, the lips and, the back. Whether they are genuine or fabricated, stigmata are still considered a medical enigma. OBJECTIVE: To summarize and analyze all available medical data about stigmata, integrating both its dermatological and psychiatric features...
April 6, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29619534/-unmet-needs-of-family-dementia-caregivers-of-persons-with-dementia-primary-medical-care
#16
REVIEW
I Zwingmann, W Hoffmann, B Michalowsky, D Wucherer, T Eichler, S Teipel, A Dreier-Wolfgramm, I Kilimann, J R Thyrian
BACKGROUND: Results of current research studies revealed that providing informal care for people with dementia (PwD) is associated with caregivers' burden and a variety of health impairments. In order to provide optimal support for family caregivers of PwD, general practitioners and specialists should be able to identify caregivers' unmet needs in primary care. OBJECTIVES: The present article provides an overview of unmet needs of family caregivers that are relevant for general practitioners as well as specialists in neurology, psychiatry, psychotherapy and psychosomatics...
April 4, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29618531/what-is-truth-the-spiritual-quest-of-forensic-psychiatry
#17
Michael A Norko
The search for truth is a foundational aim and value of forensic psychiatry. It is also a deeply spiritual exercise. It must, therefore, be possible to describe a spirituality of forensic psychiatry, which I attempt to begin in this article. This exploration opens with a discussion of spirituality and its contexts. I then examine the nature of vocation in its application to medicine, psychiatry and the law. This proceeds to a close evaluation of the attitudes and activities that I will argue occupy the groundwork of forensic practice and form pathways to truth: presence, empathy, compassion, and centering...
March 2018: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/29589121/sigmund-freud-early-network-theories-of-the-brain
#18
REVIEW
Werner Surbeck, Tim Killeen, Johannes Vetter, Gerhard Hildebrandt
Since the early days of modern neuroscience, psychological models of brain function have been a key component in the development of new knowledge. These models aim to provide a framework that allows the integration of discoveries derived from the fundamental disciplines of neuroscience, including anatomy and physiology, as well as clinical neurology and psychiatry. During the initial stages of his career, Sigmund Freud (1856-1939), became actively involved in these nascent fields with a burgeoning interest in functional neuroanatomy...
March 27, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29580705/-consultation-liaison-addiction-medicine-tools-and-specificities
#19
P Poloméni, G Cleirec, C Icard, A Ramos, B Rolland
Since the 1970s, the concept of "consultation/liaison (CL) psychiatry" has pertained to specialized mobile teams which meet inpatients hospitalized in non-psychiatric settings to offer them on-the-spot psychiatric assessment, treatment, and, if needed, adequate referral. Since the birth of CL psychiatry, a long set of theoretical books and articles has aimed at integrating CL psychiatry into the wider scope of psychosomatic medicine. In the year 2000, a circular issued by the Health Ministry defined the organization of "CL addiction services" in France...
March 23, 2018: L'Encéphale
https://www.readbyqxmd.com/read/29540116/introducing-specialist-integrated-mental-health-care-in-lebanon-the-psychosis-recovery-outreach-program
#20
Joseph El-Khoury, Rassil Ghazzaoui, Amanda Ahmad
The recognition of mental health needs in developing countries is growing in parallel with increased public awareness of and reduced stigma toward mental illness. With resources still limited in these countries, creating economically viable health care models is essential. These models are often adapted from already established and tested systems in industrialized nations. The Psychosis Recovery Outreach Program (PROP) at the American University of Beirut is an initiative that exemplifies the global transfer of knowledge, experience, and skills...
March 15, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
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