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https://www.readbyqxmd.com/read/29222675/accuracy-of-computed-tomography-for-selecting-the-revascularization-method-based-on-syntax-score-ii
#1
Si Eun Lee, Kyunghwa Han, Jin Hur, Young Jin Kim, Hye-Jeong Lee, Yoo Jin Hong, Dong Jin Im, Byoung Wook Choi
OBJECTIVES: The application of SYNTAX score II based on coronary CT angiography (CCTA) for selecting further treatment options has not been studied. This study aimed to investigate the diagnostic performance of CCTA combined with SYNTAX score II for selecting the revascularization method compared with invasive coronary angiography (ICA) based on 2014 European Society of Cardiology (ESC)/European Association for Cardio-Thoracic Surgery (EACTS) guidelines. METHODS: From January-May 2011, 160 patients who underwent both CCTA and ICA within 30 interval days were included...
December 8, 2017: European Radiology
https://www.readbyqxmd.com/read/29206072/cigarette-smoking-reduces-platelet-reactivity-independently-of-clopidogrel-treatment-in-patients-with-non-st-elevation-acute-coronary-syndromes
#2
Gabriele Crimi, Alberto Somaschini, Marco Cattaneo, Dominick J Angiolillo, Federico Piscione, Tullio Palmerini, Stefano De Servi
Smokers receiving clopidogrel show a lower residual platelet reactivity than non-smokers, a phenomenon generally ascribed to smoking-induced increased production of clopidogrel active metabolite, but also associated with the high hemoglobin levels of smokers, which decreases platelet reactivity in tests that measure platelet function in whole blood. We evaluated the impact of cigarette smoking and of hemoglobin levels on platelet reactivity index (PRI) measured by the vasodilator-stimulated phosphoprotein phosphorylation (VASP-P) assay in whole blood samples from patients with non-ST elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous coronary interventions, both before and after clopidogrel administration...
December 5, 2017: Platelets
https://www.readbyqxmd.com/read/29203885/monocyte-gene-expression-in-childhood-obesity-is-associated-with-obesity-and-complexity-of-atherosclerosis-in-adults
#3
G C Keustermans, D Kofink, A Eikendal, W de Jager, J Meerding, R Nuboer, J Waltenberger, A O Kraaijeveld, J W Jukema, J W Sels, J Garssen, B J Prakken, F W Asselbergs, E Kalkhoven, I E Hoefer, G Pasterkamp, H S Schipper
Childhood obesity coincides with increased numbers of circulating classical CD14++CD16- and intermediate CD14++CD16+ monocytes. Monocytes are key players in the development and exacerbation of atherosclerosis, which prompts the question as to whether the monocytosis in childhood obesity contributes to atherogenesis over the years. Here, we dissected the monocyte gene expression profile in childhood obesity using an Illumina microarray platform on sorted monocytes of 35 obese children and 16 lean controls. Obese children displayed a distinctive monocyte gene expression profile compared to lean controls...
December 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29195108/novel-combined-index-of-cardiometabolic-risk-related-to-periarterial-fat-improves-the-clinical-prediction-for-coronary-artery-disease-complexity
#4
Maciej Haberka, Michał Lelek, Tomasz Bochenek, Adam Kowalówka, Rafał Młynarski, Katarzyna Mizia-Stec, Zbigniew Gąsior
BACKGROUND AND AIMS: Cardiovascular (CV) risk assessment based on conventional risk factors has a limited performance in the prediction of obstructive coronary artery disease (CAD). Therefore, our aim was to provide a complete assessment on the associations between single or combined cardiovascular ultrasound indexes and the complexity of CAD in high and very-high risk patients. METHODS: Two hundred fifteen patients scheduled for elective coronary angiography were enrolled in the study (F/M: 80/135 pts; age: 61...
September 15, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29193382/prediction-of-no-reflow-and-major-adverse-cardiovascular-events-with-a-new-scoring-system-in-stemi-patients
#5
Adil Bayramoğlu, Hakan Taşolar, Ahmet Kaya, İbrahim Halil Tanboğa, Mehmet Yaman, Osman Bektaş, Zeki Yüksel Günaydın, Vecih Oduncu
BACKGROUND: No-reflow is associated with a poor prognosis in STEMI patients. There are many factors and mechanisms that contribute to the development of no-reflow, including age, reperfusion time, a high thrombus burden, Killip class, long stent use, ejection fraction ≤40, and a high Syntax score. In this study, we aimed to evaluate the parameters associated with no-reflow prediction by creating a new scoring system. METHODS: The study included 515 consecutive STEMI patients who underwent PCI; 632 STEMI patients who had undergone PCI in another center were included in the external validation of the scoring system...
November 28, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29191780/the-value-of-the-syntax-score-ii-in-predicting-clinical-outcomes-in-patients-undergoing-transcatheter-aortic-valve-implantation
#6
Nicola Ryan, Luis Nombela-Franco, Pilar Jiménez-Quevedo, Corina Biagioni, Pablo Salinas, Andrés Aldazábal, Enrico Cerrato, Nieves Gonzalo, María Del Trigo, Iván Núñez-Gil, Antonio Fernández-Ortiz, Carlos Macaya, Javier Escaned
INTRODUCTION AND OBJECTIVES: The predictive value of the SYNTAX score (SS) for clinical outcomes after transcatheter aortic valve implantation (TAVI) is very limited and could potentially be improved by the combination of anatomic and clinical variables, the SS-II. We aimed to evaluate the value of the SS-II in predicting outcomes in patients undergoing TAVI. METHODS: A total of 402 patients with severe symptomatic aortic stenosis undergoing transfemoral TAVI were included...
November 27, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29174253/the-association-of-the-syntax-score-ii-with-carotid-intima-media-thickness-and-epicardial-fat-tissue
#7
Uğur Aksu, Oktay Gulcu, Zeynep Bilgi, Selim Topcu, Serdar Sevimli, Ednan Bayram, Ibrahim Halil Tanboğa
AIM: Syntax score II (SSII) is a highly predictive scoring system, which is used to improve individualized assessment of patients with complex coronary artery disease and facilitates clinical decision making. Surrogate markers [carotid intima-media thickness (CIMT), epicardial fat tissue (EFT)] are also used for risk assessment, but their relation with SSII is not well established. METHOD: We enrolled 543 consecutive patients, who underwent coronary angiography for stable angina pectoris and acute coronary syndrome, in the study...
November 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29172653/assessment-of-relationship-between-c-reactive-protein-to-albumin-ratio-and-coronary-artery-disease-severity-in-patients-with-acute-coronary-syndrome
#8
Metin Çağdaş, Ibrahim Rencüzoğullari, Süleyman Karakoyun, Yavuz Karabağ, Mahmut Yesin, Inanç Artaç, Doğan Iliş, Öznur Sadioğlu Çağdaş, Aysu Hayriye Tezcan, Halil Ibrahim Tanboğa
The association of coronary artery disease (CAD) severity with increased C-reactive protein (CRP) and decreased albumin levels has been reported. However, to our knowledge, no study has investigated the usefulness of the CRP to albumin ratio (CAR) in predicting intermediate-high SYNergy between Percutaneous Coronary Intervention with TAXus and cardiac surgery (SYNTAX) score (SS) and high SS II. Consecutive patients (n = 344) treated with percutaneous coronary intervention comprised the study population. The study population was divided into 2 groups according to SS >22 and mean SS II values, respectively...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/29171203/association-of-syntax-score-ii-with-contrast-induced-nephropathy-and-hemodialysis-requirement-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention
#9
Ibrahim Rencuzogullari, Metin Çağdaş, Süleyman Karakoyun, Yavuz Karabağ, Mahmut Yesin, Mustafa Ozan Gürsoy, İnanç Artaç, Doğan İliş, Süleyman Çağan Efe, Kevser Tural, Ibrahim Halil Tanboğa
BACKGROUND: Contrast-induced nephropathy (CIN) is a common complication of primary percutaneous coronary intervention (pPCI) and is associated with high mortality and morbidity and long hospital stay in patients with ST elevation myocardial infarction (STEMI). The Syntax Score (SS) has previously been studied in STEMI patients, and it was associated with increased CIN development and long-term mortality. This study investigates a possible relationship between CIN development and Syntax Score II (SSII) and compares SS and SSII by assessing CIN risk in STEMI patients treated with pPCI...
November 15, 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/29168540/identification-of-a-peripheral-blood-long-non-coding-rna-upperhand-as-a-potential-diagnostic-marker-of-coronary-artery-disease
#10
Xuejie Li, Zhenzhou Zhao, Chuanyu Gao, Lixin Rao, Peiyuan Hao, Dongdong Jian, Wentao Li, Haiyu Tang, Muwei Li
BACKGROUND: Long non-coding RNAs (lncRNAs) have been confirmed to be involved in the pathological processes of multiple diseases. However, the characteristic expression of lncRNAs in peripheral blood of coronary artery disease (CAD) patients and whether some of these lncRNAs can be used as diagnostic biomarkers for CAD requires further investigation. METHODS: 6 healthy and CAD individuals were selected for microarray analysis, and 5 differentially expressed lncRNAs were selected and confirmed in the second cohort consisting of 30 control individuals and 30 CAD patients with different SYNTAX scores...
November 23, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29167614/thirty-day-and-one-year-clinical-outcomes-of-bioresorbable-vascular-scaffold-implantation-a-single-center-experience
#11
Wei-Chieh Lee, Chiung-Jen Wu, Chien-Jen Chen, Cheng-Hsu Yang, Shu-Kai Hsueh, Hon-Kan Yip, Chi-Ling Hang, Chih-Yuan Fang, Hsiu-Yu Fang
Background: Available data on the use of the Bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, CA) in real-world patients is limited, particularly in Asian populations. The aim of this study was to assess clinical outcomes of patients treated with a BVS in real-world practice in Taiwan. Methods: This study focused on 156 patients with coronary artery disease and a total of 249 lesions who received BVS implantation from October 2012 to October 2015...
November 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29160388/incremental-prognostic-value-of-the-incorporation-of-clinical-data-into-coronary-anatomy-data-in-acute-coronary-syndromes-syntax-grace-score
#12
Mateus Dos Santos Viana, Fernanda Lopes, Antonio Mauricio Dos Santos Cerqueira, Jessica Gonzalez Suerdieck, André Barcelos da Silva, Ana Clara Barcelos da Silva, Thiago Menezes Barbosa de Souza, Manuela Campelo Carvalhal, Marcia Maria Noya Rabelo, Luis Claudio Lemos Correia
BACKGROUND: When performing coronary angiography in patients with acute coronary syndrome (ACS), the anatomical extent of coronary disease usually prevails in the prognostic reasoning. It has not yet been proven if clinical data should be accounted for in risk stratification together with anatomical data. OBJECTIVE: To test the hypothesis that clinical data increment the prognostic value of anatomical data in patients with ACS. METHODS: Patients admitted with objective criteria for ACS and who underwent angiography during hospitalization were included...
November 13, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29146670/three-vessel-assessment-of-coronary-microvascular-dysfunction-in-patients-with-clinical-suspicion-of-ischemia-prospective-observational-study-with-the-index-of-microcirculatory-resistance
#13
Yuhei Kobayashi, Joo Myung Lee, William F Fearon, Jang Hoon Lee, Takeshi Nishi, Dong-Hyun Choi, Frederik M Zimmermann, Ji-Hyun Jung, Hyun-Jung Lee, Joon-Hyung Doh, Chang-Wook Nam, Eun-Seok Shin, Bon-Kwon Koo
BACKGROUND: Difficulty directly visualizing the coronary microvasculature as opposed to the epicardial coronary artery makes its assessment challenging. The goal of this study is to measure the index of microcirculatory resistance (IMR) in all 3 major coronary vessels to identify the clinical and angiographic predictors of an abnormal IMR. METHODS AND RESULTS: Ninety-three patients who underwent coronary physiological assessment in all 3 major coronary vessels were prospectively enrolled (59...
November 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29132832/the-proposed-concordance-statistic-for-benefit-provided-a-useful-metric-when-modeling-heterogeneous-treatment-effects
#14
David van Klaveren, Ewout W Steyerberg, Patrick W Serruys, David M Kent
OBJECTIVES: Clinical prediction models that support treatment decisions are usually evaluated for their ability to predict the risk of an outcome rather than treatment benefit - the difference between outcome risk with versus without therapy. We aimed to define performance metrics for a model's ability to predict treatment benefit. STUDY DESIGN AND SETTING: We analyzed data of the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) trial, and of 3 recombinant tissue plasminogen activator trials...
November 10, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29132034/impact-of-flow-mediated-dilatation-and-coronary-calcification-in-providing-complementary-information-on-the-severity-of-coronary-artery-disease
#15
Kentaro Arakawa, Mutsuki Ohno, Mutsuo Horii, Tomoaki Ishigami, Kazuo Kimura, Kouichi Tamura
BACKGROUND AND AIMS: Endothelial dysfunction and coronary artery calcification (CAC) may represent two distinct and separate processes in the development of coronary atherosclerosis. However, the interaction between these factors in determining the development of coronary artery disease (CAD) is uncertain. METHODS: Brachial artery flow-mediated dilatation (FMD) was measured by high-resolution ultrasound before coronary angiography, in 156 patients undergoing coronary CT angiography on suspicion of CAD (M/F 100/56, age 67 ± 11yrs)...
November 3, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29124470/relation-of-presystolic-wave-on-doppler-examination-to-syntax-score-in-patients-with-acute-myocardial-infarction
#16
Ihsan Dursun, Selim Kul, Sinan Sahin, Ezgi Kalaycioglu, Ali Riza Akyuz, Levent Korkmaz
BACKGROUND: There are few reports demonstrating a relationship between presystolic wave (PSW) and left ventricular function. The aim of the present study was to investigate the associations between PSW and angiographic and echocardiographic characteristics of patients with acute myocardial infarction (AMI). METHODS: We studied 348 consecutive patients with AMI. Pulsed Doppler-echocardiography was used to assess the both diastolic functions and presence of PSW from left ventricular outflow tract...
November 9, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29121234/optimizing-percutaneous-coronary-interventions-heart-team-syntax-ii-score-physiology-and-imaging-guidance-modern-stents-and-guideline-based-medication
#17
Thomas F Lüscher
No abstract text is available yet for this article.
November 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29121200/exploring-summarization-differences-for-two-types-of-expository-discourse-in-adolescents-with-traumatic-brain-injury
#18
Jennifer P Lundine, Stacy M Harnish, Rebecca J McCauley, Alexandra B Zezinka, Deena Schwen Blackett, Robert A Fox
Purpose: Annually, nearly 700,000 U.S. children and adolescents experience a traumatic brain injury (TBI). Many of them struggle academically, despite failing to qualify for special education services because their cognitive communication impairments are subtle. Method: In this exploratory study, five adolescents with TBI provided verbal summaries of two expository lectures (compare-contrast, cause-effect) and participated in cognitive and expressive syntax testing...
November 9, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29109595/the-role-of-hematological-indices-in-patients-with-acute-coronary-syndrome
#19
REVIEW
Jan Budzianowski, Konrad Pieszko, Paweł Burchardt, Janusz Rzeźniczak, Jarosław Hiczkiewicz
An increased systemic and local inflammation plays a key role in the pathophysiology of acute coronary syndrome (ACS). This review will discuss the role of hematological indices: white blood cells (WBC), neutrophil to lymphocyte ratio (NLR), red cell distribution width (RDW), and platelet indices, that is, platelet to lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet distribution width (PDW) in the case of ACS. In recent years, a strong interest has been drawn to these indices, given that they may provide independent information on pathophysiology, risk stratification, and optimal management...
2017: Disease Markers
https://www.readbyqxmd.com/read/29108790/the-association-between-electrocardiographic-r-wave-peak-time-and-coronary-artery-disease-severity-in-patients-with-non-st-segment-elevation-myocardial-infarction-and-unstable-angina-pectoris
#20
İbrahim Rencüzoğulları, Metin Çağdaş, Süleyman Karakoyun, Yavuz Karabağ, Mahmut Yesin, İnanç Artaç, Doğan İliş, Murat Selçuk, Mesut Öterkuş, Halil İbrahim Tanboğa
BACKGROUND: We aimed to evaluate possible association between QRS duration (QRSD), R wave peak time (RWPT), and coronary artery disease severity identified using the SYNTAX score (SS) in patients with unstable angina pectoris (USAP) or non-ST segment elevation myocardial infarction (NSTEMI). METHOD: A total of 176 USAP/NSTEMI patients were enrolled in the study. RESULTS: The high SS group (>22, n:45) patients had a higher prevalence of diabetes mellitus (DM); presence of ST segment depression ≥0...
September 27, 2017: Journal of Electrocardiology
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