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https://www.readbyqxmd.com/read/29452689/measurements-of-lumen-areas-and-diameters-of-proximal-and-middle-coronary-artery-segments-in-subjects-without-coronary-atherosclerosis
#1
Jaroslaw Skowronski, Jerzy Pregowski, Gary S Mintz, Mariusz Kruk, Cezary Kepka, Pawel Tyczynski, Ilona Michalowska, Lukasz Kalinczuk, Maksymilian P Opolski, Michal Ciszewski, Rafal Wolny, Zbigniew Chmielak, Adam Witkowski
There are plenty of data on morphology and lumen dimensions of diseased coronary arteries. However, information on normal coronary vessel anatomy is scarce. We provided computed tomography angiography-derived reference values of lumen dimensions in proximal and middle coronary segments in a healthy population with respect to gender and vessel dominance. Consecutive 2,849 computed tomography angiography examinations were reviewed to identify 201 subjects (77 men, patient age 50 ± 13 years) whose coronary arteries were free from any sign of atherosclerosis (calcium score 0, no detectable plaque)...
February 2, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29452484/comparison-of-patients-with-multivessel-disease-treated-at-centers-with-and-without-on-site-cardiac-surgery
#2
Eilon Ram, Ilan Goldenberg, Yigal Kassif, Amit Segev, Jakob Lavee, Nir Shlomo, Ehud Raanani
BACKGROUND: The regional needs and consolidation of cardiac surgery services (CSS) result in an increased number of stand-alone interventional cardiology units. We aimed to explore the impact of a heart team on the decision making and outcomes of patients with multivessel coronary artery disease referred for coronary revascularization in stand-alone interventional cardiology units. METHODS: This prospective study included 1063 consecutive patients with multivessel disease enrolled between January and April 2013 from all 22 hospitals in Israel that perform coronary angiography and percutaneous coronary intervention (PCI), with or without on-site CSS...
March 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29449272/differential-clinical-outcomes-between-angiographic-complete-versus-incomplete-coronary-revascularization-according-to-the-presence-of-chronic-kidney-disease-in-the-drug-eluting-stent-era
#3
Jihoon Kim, Joo Myung Lee, Ki Hong Choi, Tae-Min Rhee, Doyeon Hwang, Jonghanne Park, Chul Ahn, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Jin-Ho Choi, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon
BACKGROUND: There are limited data regarding the prognostic impact of angiographic complete revascularization (CR) in patients with chronic kidney disease (CKD). We sought to investigate the differential prognostic impact of angiographic CR over incomplete revascularization (IR), according to the presence of CKD in the drug-eluting stent era. METHODS AND RESULTS: Between 2003 and 2011 at Samsung Medical Center, consecutive patients with multivessel disease were stratified by the presence of CKD (estimated glomerular filtration rate <60 mL/min per 1...
February 15, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29447735/new-onset-atrial-fibrillation-after-pci-or-cabg-for-left-main-disease-the-excel-trial
#4
Ioanna Kosmidou, Shmuel Chen, A Pieter Kappetein, Patrick W Serruys, Bernard J Gersh, John D Puskas, David E Kandzari, David P Taggart, Marie-Claude Morice, Paweł E Buszman, Andrzej Bochenek, Erick Schampaert, Pierre Pagé, Joseph F Sabik, Thomas McAndrew, Björn Redfors, Ori Ben-Yehuda, Gregg W Stone
BACKGROUND: There is limited information on the incidence and prognostic impact of new-onset atrial fibrillation (NOAF) following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD). OBJECTIVES: This study sought to determine the incidence of NOAF following PCI and CABG for LMCAD and its effect on 3-year cardiovascular outcomes. METHODS: In the EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial, 1,905 patients with LMCAD and low or intermediate SYNTAX scores were randomized to PCI with everolimus-eluting stents versus CABG...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29445056/decreased-serum-relaxin-2-is-correlated-with-impaired-islet-%C3%AE-cell-function-in-patients-with-unstable-angina-and-abnormal-glucose-metabolism
#5
Xiangyu Gao, Hongwei Li, Ping Wang, Hui Chen
Circulating relaxin (RLX) is altered in patients with diabetes mellitus (DM) or cardiovascular diseases. This study was designed to evaluate the changes of RLX in patients with unstable angina (UA) complicated with various categories of abnormal glucose metabolism.Patients who confirmed UA by angiographic and clinical standard were grouped according to the glucose metabolism status with oral glucose tolerance test (OGTT) and medical history categorized as normal, prediabetes, newly diagnosed type 2 DM (T2DM), and previously diagnosed T2DM...
February 14, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29443740/clinical-outcomes-of-left-main-coronary-artery-disease-patients-undergoing-three-different-revascularization-approaches
#6
Chieh-Shou Su, Yu-Wei Chen, Ching-Hui Shen, Tsun-Jui Liu, Yen Chang, Wen-Lieng Lee
Significant unprotected left main (LM) coronary artery disease is frequently associated with severe multivessel disease and increased mortality and morbidity compared with non-LM coronary artery disease. This study compared the clinical outcomes of patients with LM disease who received percutaneous coronary intervention (PCI) with stenting, conventional coronary-artery bypass grafting (C-CABG), and robot-assisted CABG (R-CABG).This retrospective study analyzed 472 consecutive LM disease patients who underwent three different revascularization approaches at a tertiary medical center between January 2005 and November 2013...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29433446/homocysteine-is-a-bystander-for-st-segment-elevation-myocardial-infarction-a-case-control-study
#7
Ching-Yu Julius Chen, Tzu-Ching Yang, Christopher Chang, Shao-Chun Lu, Po-Yuan Chang
BACKGROUND: Homocysteine has been long considered a risk factor for atherosclerosis. However, cardiovascular events cannot be reduced through homocysteine lowering by B vitamin supplements. Although several association studies have reported an elevation of serum homocysteine levels in cardiovascular diseases, the relationship of homocysteine with ST-segment elevation myocardial infarction (STEMI) is not well established. METHODS: We prospectively enrolled STEMI patients who were consecutively admitted to an intensive care unit following coronary intervention in a single medical center in Taiwan...
February 13, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29406426/history-of-vasomotor-symptoms-extent-of-coronary-artery-disease-and-clinical-outcomes-after-acute-coronary-syndrome-in-postmenopausal-women
#8
Luca A Ferri, Nuccia Morici, Giorgio Bassanelli, Nicoletta Franco, Leonardo Misuraca, Laura Lenatti, Emilia Lo Jacono, Chiara Leuzzi, Elena Corrada, Tiziana C Aranzulla, Delia Colombo, Angelo Cagnacci, Francesco Prati, Stefano Savonitto
OBJECTIVE: Vasomotor symptoms (VMS) during menopausal transition have been linked to a higher burden of cardiovascular risk factors, subclinical vascular disease, and subsequent vascular events. We aim to investigate the association of VMS with the extent of coronary disease and their prognostic role after an acute coronary syndrome. METHODS: The Ladies Acute Coronary Syndrome study enrolled consecutive women with an acute coronary syndrome undergoing coronary angiography...
February 5, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29406046/effect-of-chronic-total-occlusion-percutaneous-coronary-intervention-on-clinical-outcomes-in-elderly-patients
#9
Hui-Ping Zhang, Hu Ai, Ying Zhao, Hui Li, Guo-Dong Tang, Nai-Xin Zheng, Fu-Cheng Sun, Jing-Hua Liu
BACKGROUND: There are little published data reporting the effect of coronary artery chronic total occlusion (CTO) percutaneous coronary intervention (PCI) on the prognosis of elderly patients with identified CTOs. We sought to evaluate the clinical effect of CTO PCI on the prognosis of elderly patients with CTOs. METHODS: A total of 445 consecutive patients diagnosed with a CTO by angiography from January 2011 to December 2013 were enrolled. We compared long-term clinical outcomes between the elderly group (≥75 years; n = 120, 27...
February 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29389817/early-myocardial-surgical-revascularization-after-st-segment-elevation-myocardial-infarction-in-multivessel-coronary-disease-bridge-therapy-is-the-solution
#10
Maria V Polito, Stefania Asparago, Gennaro Galasso, Rosario Farina, Antonio Panza, Severino Iesu, Federico Piscione
BACKGROUND: Many ST-segment elevation myocardial infarction (STEMI) patients have a multivessel disease that initially require percutaneous coronary intervention (PCI) of the culprit vessel but subsequently may require coronary artery bypass graft (CABG) of nonculprit vessels. Evidence supports staged revascularization, but the identification of optimal strategies (percutaneous or surgical), the timing and the management of antiplatelet therapy after recent PCI with stenting are matters of great controversies...
March 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29375221/the-association-between-monocyte-hdl-c-ratio-and-syntax-score-and-syntax-score-ii-in-stemi-patients-treated-with-primary-pci
#11
Metin Çağdaş, Süleyman Karakoyun, Mahmut Yesin, İbrahim Rencüzoğulları, Yavuz Karabağ, Mahmut Uluganyan, Mustafa Ozan Gürsoy, İnanç Artaç, Doğan İliş, Eray Atalay, Öznur Sadioğlu Çağdaş
Background: Monocyte to high-density-lipoprotein cholesterol ratio (MHR) simply reflects proatherogenic and antiatherogenic balance and high level of this ratio is associated with severity of coronary atherosclerosis and cardiac events. We investigated the association between MHR and coronary artery disease severity using SYNTAX score and SYNTAX score II (SSII) in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI). Methods: A total of 315 consecutive patients with STEMI who underwent pPCI from January 2014 to January 2016 were enrolled...
January 2018: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29372576/long-term-outcomes-of-rotational-atherectomy-of-underexpanded-stents-a-single-center-experience
#12
Marco Hernández-Enríquez, Francisco Campelo-Parada, Thibault Lhermusier, Frédéric Bouisset, Jérôme Roncalli, Meyer Elbaz, Didier Carrié, Nicolas Boudou
OBJECTIVES: To analyze the procedural and long-term outcomes of the use of rotational atherectomy (RA) in underexpanded stents in our cohort and to provide an overview of currently available data on this technique. BACKGROUND: Stent underexpansion (SU) has been related to stent thrombosis and restenosis. RA has been used to treat undilatable SU as a bail-out strategy with encouraging results. METHODS: This is an observational, single-center study...
January 25, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29361444/prognostic-implication-of-functional-incomplete-revascularization-and-residual%C3%A2-functional-syntax-score-in-patients-with-coronary-artery-disease
#13
Ki Hong Choi, Joo Myung Lee, Bon-Kwon Koo, Chang-Wook Nam, Eun-Seok Shin, Joon-Hyung Doh, Tae-Min Rhee, Doyeon Hwang, Jonghanne Park, Jinlong Zhang, Kyung-Jin Kim, Xinyang Hu, Jianan Wang, Fei Ye, Shaoliang Chen, Junqing Yang, Jiyan Chen, Nobuhiro Tanaka, Hiroyoshi Yokoi, Hitoshi Matsuo, Hiroaki Takashima, Yasutsugu Shiono, Takashi Akasaka
OBJECTIVES: The aim of this study was to investigate the prognostic implication of functional incomplete revascularization (IR) and residual functional SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score (rFSS) in comparison with 3-vessel fractional flow reserve (FFR) and residual SYNTAX score. BACKGROUND: IR is associated with poor clinical outcomes in patients who underwent percutaneous coronary intervention. METHODS: A total of 385 patients who underwent 3-vessel FFR measurement after stent implantation were included in this study...
January 11, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29361323/accuracy-of-the-timi-and-grace-scores-in-predicting-coronary-disease-in-patients-with-non-st-elevation-acute-coronary-syndrome
#14
Rania Hammami, Jihen Jdidi, Fakher Mroua, Rahma Kallel, Mourad Hentati, Leila Abid, Samir Kammoun
INTRODUCTION: The GRACE and TIMI scores have been well validated for assessment of prognosis in non-ST-elevation acute coronary syndrome (NSTE-ACS). However, their value in predicting coronary artery disease (CAD) has been little studied. We aimed to assess the relationship between these scores and the extent of coronary disease. METHODS: We analyzed 238 consecutive patients admitted for NSTE-ACS and undergoing a coronary angiogram during hospitalization. The severity of CAD was assessed using the SYNTAX score...
January 17, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29357762/outcome-and-selection-of-revascularization-strategy-in-left-main-coronary-artery-stenosis
#15
Thomas Gripenberg, Fadi Jokhaji, Nikolaos Östlund-Papadogeorgos, Christina Ekenbäck, Rikard Linder, Bassem Samad, Jonas Persson
OBJECTIVES: To investigate clinical outcome in unselected real-life patients with unprotected left main coronary artery (ULMCA) stenosis and determine factors associated with selection of revascularization strategy. DESIGN: Consecutive patients with ULMCA stenosis at our institution in 2009-2013 (n = 308) were retrospectively analyzed with propensity score adjusted Cox proportional hazards models for outcome. Baseline characteristics in relation to selection of revascularization strategy were analyzed with multivariate logistic regression...
January 22, 2018: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/29350388/chronic-statin-treatment-is-a-predictor-of-pre-interventional-infarct-related-artery-patency-in-patients-with-st-elevation-myocardial-infarction-treated-with-percutaneous-coronary-intervention
#16
Süleyman Özbiçer, Mustafa Gür, Gülhan Kalkan, Betül Özaltun, Murat Çaylı
BACKGROUND: Beyond lipid-lowering effects, early statin treatment has beneficial effects on prognosis after acute coronary syndrome. Infarct related artery patency before percutaneous coronary intervention is known to be a strong predictor of improved clinical outcome. AIM: We aimed to investigate the effects of chronic statin treatment before admission on the infarct related artery patency after infarction. METHODS: In this study, 938 ST elevation myocardial infarction patients admitted to the hospital within the first 12 hours of symptom onset were prospectively enrolled (682 male, 256 female; mean age 58...
January 19, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29326773/clinical-outcomes-of-patients-undergoing-rotational-atherectomy-followed-by-drug-eluting-stent-implantation-a-single-center-real-world-experience
#17
Lucky R Cuenza, Ada Cherryl Jayme, James Ho Khe Sui
Background: Rotational atherectomy (RA) is used to improve procedural success of percutaneous catheter interventions (PCIs) of complex and heavily calcified coronary lesions. We report the clinical experience and outcomes in our institution with the use of RA, followed by drug-eluting stent implantation. Materials and Methods: Data of 81 patients treated with PCI and adjunctive RA were analyzed. Clinical follow-up for the occurrence of major adverse events (MAEs) was obtained in all patients and correlated with significant variables using multivariate Cox proportional hazards analysis...
October 2017: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/29317974/global-risk-score-and-clinical-syntax-score-as-predictors-of-clinical-outcomes-of-patients-undergoing-unprotected-left-main-percutaneous-catheter-intervention
#18
Lucky Cuenza, Marianne P Collado, James Ho Khe Sui
Background: Risk stratification is an important component of left main percutaneous catheter intervention (PCI) which has emerged as a feasible alternative to cardiac surgery. We sought to compare the clinical SYNTAX score and the global risk score in predicting outcomes of patients undergoing unprotected left main PCI in our institution. Methods: Clinical, angiographic and procedural characteristics of 92 patients who underwent unprotected left main PCI (mean age 62 ± 12...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29313562/the-associat%C3%A4-on-between-serum-serglycin-level-and-coronary-artery-disease-severity-in-patients-with-stable-angina-pectoris
#19
Hasan Ata Bolayır, Tarık Kıvrak, Hakan Gunes, Aslı Bolayır, Ilgın Karaca
BACKGROUND AND AIM: Serglycin has an important role in the inflammatory status and the relationship between coronary artery disease (CAD) and serglycin is still unknown. In this study, we aimed to investigate association of serglycin level with CAD severity in patients with stable angina pectoris (SAP). METHODS: Overall, 100 SAP patients diagnosed by coronary angiography and clinical manifestations and 100 control subjects matched for age and gender were enrolled in this case-control study...
January 9, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29310455/association-between-serum-ldl-c-and-apob-and-syntax-score-in-patients-with-stable-coronary-artery-disease
#20
Taiwu Lin, Luzhao Wang, Jingbin Guo, Peng Liu, Liheng Chen, Mengqiu Wei, Gongxin Li
The aim of this study was to examine the relationship between low-density lipoprotein cholesterol (LDL-C) and apolipoprotein (Apo) B levels and the SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) score (SS) in patients with stable angina pectoris. We enrolled 594 patients who were suspected to have coronary heart disease (CHD) and who underwent coronary angiography. Patients were divided into 4 groups based on the SS: normal (SS = 0, n = 154), low SS (SS ≤ 22, n = 210), intermediate SS (22 < SS < 32, n = 122), and high SS (SS ≥ 33, n = 63)...
January 1, 2018: Angiology
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