keyword
MENU ▼
Read by QxMD icon Read
search

Cervical cytology

keyword
https://www.readbyqxmd.com/read/29331885/autonomously-hyperfunctioning-cystic-nodule-harbouring-thyroid-carcinoma-case-report-and-literature-review
#1
Maria João Lima, Virgínia Soares, Pedro Koch, Artur Silva, António Taveira-Gomes
INTRODUCTION: Hyperthyroidism is rarely associated with malignancy, but it cannot rule out thyroid cancer. Although there is published data describing this coexistence, thyroid carcinomas inside autonomously functioning nodules are uncommon. PRESENTATION OF CASE: A 49-year-old woman presented with a cervical mass, unexplained weight loss and anxiousness, sweating and insomnia. On physical examination, she had a palpable left thyroid nodule. Thyroid function tests showed suppressed TSH (<0,1 uUI/mL), thyroxine 1,44 ng/dL (normal range 0,70-1,48) and triiodothyronine 4,33 pg/mL (normal range 1,71-3,71)...
January 8, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29328473/detection-of-high-grade-neoplasia-in-air-dried-cervical-pap-smears-by-a-microrna-based-classifier
#2
Mikhail K Ivanov, Sergei E Titov, Sergei A Glushkov, Victoria V Dzyubenko, Anastasia V Malek, Polina A Arkhangelskaya, Roman B Samsonov, Andrey A Mikhetko, Elena V Bakhidze, Igor V Berlev, Nikolay N Kolesnikov
Recent studies have shown that changes in the expression levels of certain microRNAs correlate with the degree of severity of cervical lesions. The aim of the present study was to develop a microRNA-based classifier for the detection of high-grade cervical intraepithelial neoplasia (CIN ≥2) in cytological samples from patients with different high-risk human papillomavirus (HR-HPV) viral loads. For this purpose, raw RT-qPCR data for 25 candidate microRNAs, U6 snRNA and human DNA in air-dried PAP smears from 174 women with different cervical cytological diagnoses, 144 of which were HR-HPV-positive [40 negative for intraepithelial lesion or malignancy (NILM), 34 low-grade squamous intraepithelial lesions (L-SIL), 57 high-grade squamous intraepithelial lesions (H-SIL), 43 invasive cancers], were statistically processed...
January 12, 2018: Oncology Reports
https://www.readbyqxmd.com/read/29327734/clinical-study-of-extrapulmonary-head-and-neck-tuberculosis-in-an-urban-setting
#3
S Monga, J N Malik, S Jan, S Bahadur, S Jetley, H Kaur
Tuberculosis (TB) of the head and neck region is quite common in endemic countries, but is still misdiagnosed due to its varied presentation and different sites of involvement. The aims of the present study were to present the diversities of presentation of head and neck tuberculosis with the diagnostic predicaments faced during evaluation and to assess treatment response to anti-tubercular treatment (ATT). We analysed 48 patients with head and neck tuberculosis who presented to the Department of Otorhinolaryngology in our tertiary care urban hospital over a period of two years from 2013 to 2015 and recorded their data, which included presenting complaints, local and systemic examination findings, investigation results and treatment outcomes...
December 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29327232/comparative-evaluation-of-the-omniplex-hpv-and-rfmp-hpv-papillotyper-for-detecting-human-papillomavirus-genotypes-in-cervical-specimens
#4
Young Ahn Yoon, Bo-Hyun Kim, Su-Hak Heo, Hwi Jun Kim, Young-Jin Choi
Human papillomavirus (HPV) is a major cause of cervical neoplasia development. HPV screening is very important because early treatment can prevent cervical cancer. Omniplex-HPV is a polymerase chain reaction followed by Luminex xMAP bead microarray technology that is designed for detecting 40 HPV genotypes. The aim of this study is to evaluate the analytical and clinical performance of the Omniplex-HPV in comparison with that of the commercially available RFMP (restriction fragment mass polymorphism) HPV PapilloTyper...
January 11, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29326178/impact-of-replacing-cytology-with-human-papillomavirus-testing-for-cervical-cancer-screening-on-the-prevalence-of-trichomonas-vaginalis-a-modelling-study
#5
Ben B Hui, Caitlin P Reulein, Rebecca J Guy, Basil Donovan, Jane S Hocking, Matthew G Law, David G Regan
OBJECTIVES: Trichomonas vaginalis (TV) is the most common curable STI worldwide and is associated with increased risk of HIV acquisition and serious reproductive morbidities. The prevalence of TV infection is very low in Australian cities, and this is thought to be at least partly due to incidental detection and treatment of TV in women participating in the cervical cytology screening programme. In 2017, the national cervical screening programme will transition to a new model based on testing for high-risk (HR) human papillomavirus (HPV), with a reduced frequency and commencement at an older age...
January 11, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29322839/feasibility-study-of-a-human-papillomavirus-e6-and-e7-oncoprotein-test-for-the-diagnosis-of-cervical-precancer-and-cancer
#6
Jin-Jun Zhang, Xin-Chun Cao, Xiang-Yu Zheng, Hai-Ying Wang, Yong-Wei Li
Objective To evaluate the clinical value of human papillomavirus (HPV) E6 and E7 oncoprotein (HPV E6/E7) detection in the early screening of cervical cancer. Methods This prospective study evaluated all patients with suspected cervical intraepithelial neoplasia (CIN) as identified by the presence of at least one positive indicator from a ThinPrep cytologic test (TCT) and/or a Hybrid Capture 2 (HC2) HPV DNA test. The levels of E6/E7 oncoproteins were determined using Western blot analysis. The diagnostic value of the HPV E6/E7 protein assay was compared with the clinical diagnosis from TCT, HC2 and the gold standard of cervical biopsy histology...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29320507/hpv-prevalence-and-hpv-related-dysplasia-in-elderly-women
#7
Ruth S Hermansson, Matts Olovsson, Emelie Hoxell, Annika K Lindström
INTRODUCTION: In Sweden, where screening ends at the age of 60, about 30% of the cervical cancer cases occur in women older than 60. The aim of the present study was to investigate the prevalence of HPV and cervical dysplasia in women of 60 years and above. PATIENTS AND METHODS: From September 2013 until June 2015, 1051 women aged 60-89 years (mean 68 years) were sampled for an HPV test when attending an outpatient gynecology clinic. Women with positive results had a second HPV test and liquid based cytology (LBC), after 3...
2018: PloS One
https://www.readbyqxmd.com/read/29302583/tp53-r72p-polymorphism-and-susceptibility-to-human-papillomavirus-infection-among-women-with-human-immunodeficiency-virus-in-morocco-a-case-control-study
#8
Ahd Oulad Lahsen, Hanâ Baba, Rajaa Bensghir, Naouar Fayssel, Mustapha Sodqi, Latifa Marih, Sellama Nadifi, Lahcen Wakrim, Kamal Marhoum El Filali, Sayeh Ezzikouri
Background: Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide. HPV is the main causative agent for cervical cancer. The HPV oncoprotein E6 binds to the tumor suppressor gene product p53, promoting its degradation; the Arg allele of TP53 R72P polymorphism binds more ardently with HPV E6 than the Pro variant. Here, we investigated whether TP53 R72P gene variant, rs104252, was associated with susceptibility to HPV infection in women with human immunodeficiency virus (HIV)...
December 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29289814/safety-and-acceptability-of-human-papillomavirus-testing-of-self-collected-specimens-a-methodologic-study-of-the-impact-of-collection-devices-and-hpv-assays-on-sensitivity-for-cervical-cancer-and-high-grade-lesions
#9
Maarit K Leinonen, Kristina Schee, Christine M Jonassen, A Kathrine Lie, Camilla F Nystrand, Anbjørg Rangberg, Ingegerd E Furre, Marzena J Johansson, Ameli Tropé, Katrine D Sjøborg, Philip E Castle, Mari Nygård
BACKGROUND: Comparative data on different self-collection methods is limited. OBJECTIVES: To assess the impact of hrHPV testing of two self-collection devices for detection of cervical carcinoma and high-grade lesions. STUDY DESIGN: Three hundred ten patients collected two cervicovaginal specimens using a brush (Evalyn®Brush) and a swab (FLOQSwabs™), and filled a questionnaire at home. Then, a physician at the clinic took a cervical specimen into PreservCyt® buffer for hrHPV testing and cytology...
December 21, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29288782/adherence-patterns-to-extended-cervical-screening-intervals-in-women-undergoing-human-papillomavirus-hpv-and-cytology-cotesting
#10
Katharine A Rendle, Mark Schiffman, Li C Cheung, Walter K Kinney, Barbara Fetterman, Nancy E Poitras, Thomas Lorey, Philip E Castle
Although guidelines have recommended extended interval cervical screening using concurrent human papillomavirus (HPV) and cytology ("cotesting") for over a decade, little is known about its adoption into routine care. Using longitudinal medical record data (2003-2015) from Kaiser Permanente Northern California (KPNC), which adopted triennial cotesting in 2003, we examined adherence to extended interval screening. We analyzed predictors of screening intervals among 491,588 women undergoing routine screening, categorizing interval length into early (<2...
December 27, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29288321/rassf1a-promoter-methylation-was-associated-with-the-development-progression-and-metastasis-of-cervical-carcinoma-a-meta-analysis-with-trial-sequential-analysis
#11
Fei Zheng, Huimin Yu
BACKGROUND: RASSF1A promoter methylation has been reported in cervical cancer. However, clinical effect of RASSF1A promoter methylation in cervical cancer remains unclear. This meta-analysis was conducted to assess the correlation between RASSF1A promoter methylation and cervical cancer and the association of RASSF1A promoter methylation with clinicopathological features. METHODS: Electronic databases were searched to identify eligible publications. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated...
December 29, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29285369/clinical-significance-of-atypical-squamous-cells-of-undetermined-significance-after-treatment-for-cervical-intraepithelial-grade-3-neoplasia-a-retrospective-single-center-cohort-study
#12
Toshimichi Onuma, Kimihisa Tajima, Kumiko Sato, Katsushige Hattori, Shin Fukuda, Takahiro Tsuji, Yoshio Yoshida
The aim of the present study was to evaluate the clinical significance of atypical squamous cells of undetermined significance (ASC-US) following cervical conization for cervical intraepithelial neoplasia (CIN) grade 3. This study was a retrospective cohort analysis. The medical records of women treated with conization for CIN 2-3 were reviewed and 142 patients with CIN 3 who had been diagnosed using the conization specimens were selected. The mean follow-up period after conization was 41.8 months. Cytological abnormalities after conization were observed in 19...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29285356/effect-of-paiteling-on-human-papillomavirus-infection-of-the-cervix
#13
Pingping Tao, Weiping Zheng, Xiaohua Meng, Junxia Chen, Aijing Sun, Qinghe Shou, Yungen Wang, Binlie Yang
The aim of the present study was to investigate the effect of the traditional Chinese medicine paiteling on the outcome of high-risk human papillomavirus (HR-HPV) infection of the cervix. A total of 321 patients were enrolled in this study and HPV subtypes were determined by the Hybribio HPV genotyping system. The patients were divided into the loop electrosurgical excision procedure (LEEP; n=82) and non-LEEP (n=239) groups, according to the cervical intraepithelial neoplasia classification. These two groups were further subdivided into the drug (paiteling) and control subgroups...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29285261/use-of-autoantibodies-against-tumor-associated-antigens-as-serum-biomarkers-for-primary-screening-of-cervical-cancer
#14
Yingji Jin, Seung Cheol Kim, Hyoung Jin Kim, Woong Ju, Yun Hwan Kim, Hong-Jin Kim
Serum autoantibodies against tumor-associated antigens (TAAs) have received much attention as potential biomarkers for early detection of cancers, since they can be detected in the early stages of cancers. Autoantibodies against Cancer Antigen 15-3 (CA15-3), carcinoembryonic antigen (CEA), Cancer Antigen 19-9 (CA19-9), c-Myc, p53, heat shock protein (Hsp)27 and Hsp70 have been suggested as potential markers for detecting several types of cancer. In the present study, the seven types of antibody listed above were evaluated for detecting cervical lesions...
December 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/29284496/high-cea-levels-in-a-case-of-resected-colorectal-cancer-delayed-diagnosis-of-metachronous-medullary-thyroid-cancer
#15
Shih-Wei Chen, Yen-Kung Chen
BACKGROUND: Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers, and its value in the surveillance of post-operative colorectal cancer is well established. Fluorodeoxyglucose-positron emission tomography (FDG-PET) has been clinically used in colorectal cancer imaging including preoperative staging, evaluation of therapeutic response, detection of disease recurrence, and investigation of unexplained rising tumor markers. CASE PRESENTATION: We report a case of resected colorectal cancer presented with rising CEA levels in 5 years, and FDG-PET revealed no definitive evidence of recurrence except abnormal focal FDG uptake in the right thyroid lobe...
December 29, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29284230/new-directions-in-cervical-cancer-prophylaxis-worldwide-and-in-poland-case-study-of-the-polish-rural-female-population
#16
Agnieszka Maździarz, Jerzy Wyględowski, Beata Osuch, Beata Jagielska, Beata Śpiewankiewicz
INTRODUCTION: Cervical cancer is one of the most frequent malignant neoplasms in females. Such neoplasms can be almost completely eliminated by means of adequate primary and secondary prophylaxis. The most developed countries focus their attention on the improvement of prophylaxis systems, test quality, and efficacy improvement, as well as on the expansion of the primary prophylaxis. In Poland, the discussions focus on the improvement of the malfunctioning population programme. OBJECTIVE: Drawing on recent research findings, the article presents current Polish and global recommendations with regard to screening tests for cervical cancer...
December 23, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29284025/clinical-management-and-risk-reduction-in-women-with-low-grade-squamous-intraepithelial-lesion-cytology-a-population-based-cohort-study
#17
Yi-Jou Tai, Yun-Yuan Chen, Huang-Cheng Hsu, Chun-Ju Chiang, San-Lin You, Hui-Chi Chen, Chi-An Chen, Wen-Fang Cheng
We analyzed the management and risk of subsequent cervical intraepithelial neoplasm 3 (CIN3) and invasive cervical cancer in women with low-grade squamous intraepithelial lesion (LSIL) cytology. A total of 53,293 women with a new diagnosis of cytologic LSIL were identified in Taiwan's national cervical screening registration database. Based on the retrieved clinical management data, the incidence of subsequent CIN3+ lesions was determined, and the hazard ratios (HRs) were estimated using a Cox proportional hazards model...
2017: PloS One
https://www.readbyqxmd.com/read/29282522/the-incidence-of-malignancy-in-clinically-benign-cystic-lesions-of-the-lateral-neck-our-experience-and-proposed-diagnostic-algorithm
#18
Moshe Yehuda, Melissa E Schechter, Nora Abu-Ghanem, Gilad Golan, Gilad Horowitz, Dan M Fliss, Sara Abu-Ghanem
AIM: Solitary cystic masses of the lateral neck in an adult patient can pose a diagnostic dilemma. Malignancy must be ruled out since metastases arising from H&N cancers may mimic the presentation of benign cystic masses. Only a small number of studies have investigated the diagnostic management and malignancy rate of clinically benign solitary cervical cystic lesions. There are no established guidelines for the diagnostic evaluation. METHODS: Retrospective review of the clinical, cytological, radiological, and pathological records of all adult patients (> 18 years) operated on for second branchial cleft cysts (BrCC) between 1/2008-2010/2016...
December 27, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29280216/contribution-of-cervical-cytology-in-the-diagnostic-work-up-of-patients-with-endometrial-cancer
#19
L C M Amkreutz, J M A Pijnenborg, D W L Joosten, H J M M Mertens, S M J Van Kuijk, M J A Engelen, M Bergmans, W E Nolting, R F P M Kruitwagen
INTRODUCTION: Abnormal cervical cytology in patients with endometrial cancer (EC) has been associated with poor outcome. The aim of this study was to evaluate whether cervical cytology could contribute to an improved preoperative identification of high-grade EC (serous, clear cell, carcinosarcoma, high-grade endometrioid EC) in final histology. METHODS: A retrospective cohort study was performed in five hospitals in the Netherlands. A total of 554 patients with EC that underwent primary surgical treatment between 2002 and 2010 were included...
December 27, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29279588/comparison-of-the-sensitivity-and-specificity-of-p16-ki-67-dual-staining-and-hpv-dna-testing-of-abnormal-cervical-cytology-in-the-detection-of-histology-proven-cervical-intraepithelial-neoplasia-grade-2-and-above-cin-2
#20
T K Y Tay, K L Lim, M H Hilmy, A A Thike, S T Goh, L H Song, J S G Hwang, S Mantoo
INTRODUCTION: Human papillomavirus (HPV) testing is used as a means of triaging cervico-vaginal smears with low grade squamous abnormalities or as part of co-testing with cytology. While HPV testing has a high sensitivity, it has a low specificity in detecting cervical intraepithelial neoplasia grade 2 and above (CIN 2+) leading to unnecessary colposcopy referrals. We investigate the accuracy of the p16/Ki-67 dual immunocytochemical stain in determining the presence of CIN 2+ lesions on histology and its potential as a superior biomarker for triage...
December 2017: Malaysian Journal of Pathology
keyword
keyword
40727
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"