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https://www.readbyqxmd.com/read/29243368/a-2000-patient-retrospective-assessment-of-a-new-strategy-for-burn-wound-management-in-view-of-infection-prevention-and-treatment
#1
Justyna Glik, Wojciech Łabuś, Diana Kitala, Karolina Mikuś-Zagórska, Christopher D Roberts, Mariusz Nowak, Aleksandra Kasperczyk, Marek Kawecki
Infections in burn patients are still the principal cause of complications in burn injuries. The aim of this study is to assess a new strategy for burn wound management in view of infection prevention and treatment in the experience of the Burn Treatment Center in Siemianowice Śląskie. The applied methodology involved the analysis of patient records describing the hospital's epidemiological situation between 2014 and 2016. The analysis also included the use and cost of antibiotics, silver-containing dressings, and other antiseptics relative to the number of sepsis cases, including those caused by Pseudomonas aeruginosa, as well as the mortality ratio...
December 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29232530/pediatric-endoscopic-pilonidal-sinus-treatment-a-revolutionary-technique-to-adopt-in-children-with-pilonidal-sinus-fistulas-our-preliminary-experience
#2
Ciro Esposito, Serena Izzo, Francesco Turrà, Mariapina Cerulo, Giovanni Severino, Alessandro Settimi, Marta Iannazzone, Lorenzo Masieri, Giuseppe Cortese, Maria Escolino
AIM: This study aimed to report our preliminary experience with pediatric endoscopic pilonidal sinus treatment (PEPSiT). PATIENTS AND METHODS: We retrospectively reviewed the reports of 15 patients, 6 girls and 9 boys, with an average age of 16 years (range 13-18) with noninfected pilonidal sinus disease who underwent PEPSiT in our institution over an 18-month period. Four cases were redo-procedures, for recurrence of disease after open excision repair. Surgical outcomes of sinus healing, recurrence of disease, postoperative pain, hospital stay, analgesic requirements, and patient satisfaction levels were evaluated and a comparison analysis with classic open repair was performed...
December 12, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29222019/a-novel-use-of-cellulose-based-filter-paper-containing-silver-nanoparticles-for-its-potential-application-as-wound-dressing-agent
#3
Adnan Haider, Sajjad Haider, Inn-Kyu Kang, Anuj Kumar, Madhusudana Rao Kummara, Tahseen Kamal, Sung Soo Han
The frequent use of antibiotics against microbial infections may lead the emergence of antibiotic resistant microbial strains. To overcome these microbial strains, we need to fabricate alternative materials which can handle them. It is for this reason, we have fabricated cellulose (CE) based filter paper (FP) composite scaffolds comprising of adsorbed chitosan (CS) and sliver (Ag) nanoparticles (NPs). The AgNPs are incorporated in the CS layer of the composite scaffold. Prior to evaluate the efficacy of the scaffolds against gram positive and gram negative bacterial strains, the scaffolds were characterized for the presence of the Ag NPs with field emission scanning electron microscope (FE-SEM), fourier transform infrared (FTIR) spectroscopy and x-ray diffractometer (XRD)...
December 5, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29216782/reduction-in-central-line-associated-bloodstream-infections-correlated-with-the-introduction-of-a-novel-silver-plated-dressing-for-central-venous-catheters-and-maintained-for-6-years
#4
Rachel Karlnoski, Elia Charbel Abboud, Peggy Thompson, Asa Z Oxner, John T Sinnott, Jorge E Marcet
OBJECTIVE: To assess a novel silver-plated dressing (SD) for central venous catheters in comparison to chlorhexidine gluconate-impregnated sponge (CHGIS) dressings in preventing central line-associated bloodstream infections (CLABSIs) in adult intensive care unit (ICU) patients. DESIGN: Retrospective cohort study. SETTING: Tampa General Hospital, an academic medical tertiary care center. PATIENTS: All adult ICU patients of an academic medical tertiary care center from January 2009 to December 2010...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29197891/management-of-malodour-fungating-wound-with-nanocrystalline-silver-coated-dressing
#5
W Steffi, B Zaliana, A Amreen, N Nasirudin
Chronic exudative malodorous fungating wound of four years at the right arm due to diffuse large B cell lymphoma managed with silver dressings. In two months of application with nanocrystalline silver coated dressings, there was significant improvement in wound.
October 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/29161306/comparison-of-methods-for-determining-the-effectiveness-of-antibacterial-functionalized-textiles
#6
Hajo Haase, Lisa Jordan, Laura Keitel, Claudia Keil, Boris Mahltig
Antimicrobial functionalization of textiles is important for various applications, such as protection of textile materials from decomposition, generation of more effective wound dressings, and the prevention of infections or malodors resulting from bacterial growth. In order to test the efficacy of new products, their antibacterial activity needs to be evaluated. At present, several different procedures are being used for this purpose, hindering comparisons among different studies. The present paper compares five of these assays using a sample panel of different textiles functionalized with copper (Cu) and silver (Ag) as antibacterial agents, and discusses the suitability of these methods for different analytical requirements...
2017: PloS One
https://www.readbyqxmd.com/read/29155834/measuring-the-microbiome-of-chronic-wounds-with-use-of-a-topical-antimicrobial-dressing-a-feasibility-study
#7
Lindsay Kalan, Mi Zhou, Michele Labbie, Benjamin Willing
BACKGROUND: Polymicrobial communities colonize all wounds, and biofilms are hypothesized to be a key link to the chronic state and stalled healing. Molecular methods offer greater insight when studying microbial ecology in chronic wounds, as only a small fraction of wound bacteria are cultured by currently available methods and studies have shown little agreement between culture and molecular based approaches. Some interventions, like dressings with oxidized silver, are reported to help the stalled wounds move to a normal healing trajectory but the underlying mechanisms are difficult to measure...
2017: PloS One
https://www.readbyqxmd.com/read/29155402/synthesis-of-silver-nanoparticles-from-a-desmodium-adscendens-extract-and-its-antibacterial-evaluation-on-wound-dressing-material
#8
Jaya R Lakkakula, Derek Tantoh Ndinteh, Sandy F van Vuuren, Denise K Olivier, Rui W M Krause
The one-pot synthesis of silver nanoparticles (AgNPs) using the medium-polar extract of Desmodium adscendens (Sw.) DC. is presented here as an alternative synthesis of metal NPs. Characterisation of the formed NPs showed polydispersed AgNPs ranging from 15 to 100 nm where the concentration of metal ions was found to play a role in the size and shape of the prepared NPs. It could be established that the flavonoids, saponins, and alkaloids present in the extract acted as both reducing and stabilising agents during the formation of the capped metal NPs...
December 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/29142544/effect-of-oil-gauze-silver-dressings-on-diabetic-foot-ulcers-in-the-elderly
#9
Chang Yan Dong, Wen Juan Liu, Rong Xiang Chi, Hong Du
Objective: To compare the clinical efficacy and safety of oil gauze silver dressing and silver ions dressing on diabetic ulcers in elderly outpatients. Methods: Twenty-two patients with Type-2 diabetic foot ulcers were included in the study conducted at Yantai Yuhuangding Hospital between April 2013 and April 2014. At the time of enrolment they were divided into the silver ions and oil gauze silver groups based on the order of admission. Dressings were changed twice weekly until the ulcer had healed...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29101755/sub-cytotoxic-concentrations-of-ionic-silver-promote-the-proliferation-of-human-keratinocytes-by-inducing-the-production-of-reactive-oxygen-species
#10
Xiaodong Duan, Daizhi Peng, Yilan Zhang, Yalan Huang, Xiao Liu, Ruifu Li, Xin Zhou, Jing Liu
Silver-containing preparations are widely used in the management of skin wounds, but the effects of silver ions on skin wound healing remain poorly understood. This study investigated the effects of silver ions (Ag(+)) on the proliferation of human skin keratinocytes (HaCaT) and the production of intracellular reactive oxygen species (ROS). After treating HaCaT cells with Ag(+) and/or the active oxygen scavenger N-acetyl cysteine (NAC), cell proliferation and intracellular ROS generation were assessed using CCK-8 reagent and DCFH-DA fluorescent probe, respectively...
November 3, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/29066250/corrigendum-to-silver-impregnated-occlusive-dressing-reduces-rates-of-acute-periprosthetic-joint-infection-after-total-joint-arthroplasty-journal-of-arthroplasty-32-2017-929-932
#11
Matthew J Grosso, Ari Berg, Samuel LaRussa, Taylor Murtaugh, David P Trofa, Jeffrey A Geller
No abstract text is available yet for this article.
October 21, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29064431/release-behavior-and-antibacterial-activity-of-chitosan-alginate-blends-with-aloe-vera-and-silver-nanoparticles
#12
Luisa Fernanda Gómez Chabala, Claudia Elena Echeverri Cuartas, Martha Elena Londoño López
Aloe vera is a perennial plant employed for medical, pharmaceutical and cosmetic purposes that is rich in amino acids, enzymes, vitamins and polysaccharides, which are responsible for its therapeutic properties. Incorporating these properties into a biopolymer film obtained from alginate and chitosan allowed the development of a novel wound dressing with antibacterial capacity and healing effects to integrate the antibacterial capacity of silver nanoparticles with the healing and emollient properties of Aloe vera gel...
October 24, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29032975/comparison-of-non-surgical-methods-for-the-treatment-of-deep-partial-thickness-skin-burns-of-the-hand
#13
Ernest Zacharevskij, Gytis Baranauskas, Karolis Varkalys, Rytis Rimdeika, Darius Kubilius
This paper describes a randomized, controlled, parallel-group, single-center clinical trial designed to compare non surgical treatment methods of deep partial thickness skin burns of the hand. All patients were scanned with the Laser Doppler Imaging device to determine the depth of the burn wound. Viable keratinocytes sites were determined according to the established Perfusion Units (PU) measurement system. The trial enrolled 87 patients with hand burn wounds in the section of 260-600PU. Hand burn patients were divided into the following four groups: treated with hydrocolloid dressings; treated with mechanical debridement of monofilament polyester fibers pad and then applying silver sulfadiazine; treated with gauze dressings containing enzymatic collagenase preparation...
October 9, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28979327/fabrication-and-physicochemical-investigation-of-ancient-iranian-and-pakistani-treated-silver-particles-and-their-comparison-with-silver-nanoparticles
#14
Soheyla Honary, Alireza Mozaffari Dehshiri, Mahmoud Mosaddegh
Silver compounds are known to be both toxic and carcinogenic. However, silver nanoparticles have been showed diagnostic and therapeutic value. They can be used as biological tags for a quantitative detection and/or be incorporated into wound dressings and cosmetics due to their antibacterial properties. Pakistani and Iranian traditional physicians still take the advantage of silver compounds, called silver Kushta, to treat dementia, leprosy, and skin cancers. The present study compared the physicochemical properties of silver nanoparticles (AgNPs) and silver Kushtas (Pakistani silver Kushta (PKAg) and Iranian silver) in terms of the morphology, silver content, chemical composition, and suspension stability...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28974093/silver-inlaid-with-gold-nanoparticle-chitosan-wound-dressing-enhances-antibacterial-activity-and-porosity-and-promotes-wound-healing
#15
Qing Li, Fei Lu, Guofang Zhou, Kun Yu, Bitao Lu, Yang Xiao, Fangying Dai, Dayang Wu, Guangqian Lan
Silver inlaid with gold nanoparticles (Au-Ag NPs) prepared by using egg white with an average sized of 10 nm and homogeneous dispersion were tested and presented red fluorescence. Au-Ag NPs were loaded into chitosan as wound dressing (CS-Au-Ag). CS-Au-Ag released silver ions faster, in higher amount, and in a more durable manner than chitosan dressing loaded with silver nanoparticles with the same silver content (CS-Ag), consequently, showing enhanced antibacterial activity. Cytotoxicity tests indicated that CS-Au-Ag showed low cytotoxicity to L929 cells similar to CS-Ag...
October 11, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28934124/n-halamine-biocidal-materials-with-superior-antimicrobial-efficacies-for-wound-dressings
#16
Buket Demir, Roy M Broughton, Mingyu Qiao, Tung-Shi Huang, S D Worley
This work demonstrated the successful application of N-halamine technology for wound dressings rendered antimicrobial by facile and inexpensive processes. Four N-halamine compounds, which possess different functional groups and chemistry, were synthesized. The N-halamine compounds, which contained oxidative chlorine, the source of antimicrobial activity, were impregnated into or coated onto standard non-antimicrobial wound dressings. N-halamine-employed wound dressings inactivated about 6 to 7 logs of Staphylococcus aureus and Pseudomonas aeruginosa bacteria in brief periods of contact time...
September 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28929069/our-experience-of-treating-wide-spectrum-of-external-ear-canal-atresia-of-different-etiologies-in-pediatric-patients
#17
Kranti Bhavana
External auditory canal atresia (EACA) is a common otologic condition. Etiology can vary from congenital to acquired causes. It causes considerable difficulty to the patient. Bilateral ear canal atresia in children can lead to speech delays due to hearing impairment caused by this condition. Though easily diagnosed it is one of the most difficult conditions to treat. Acquired conditions can affect any age group. Restenosis following treatment is very common. This article focuses on the treatment of EACA due to different etiologies and emphasizes on special points of surgical treatment and follow up...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28914681/randomized-controlled-trial-comparing-collagen-oxidized-regenerated-cellulose-silver-to-standard-of-care-in-the-management-of-venous-leg-ulcers
#18
Breda M Cullen, Thomas E Serena, Molly C Gibson, Robert J Snyder, Jason R Hanft, Raphael A Yaakov
OBJECTIVE: To assess healing outcomes in venous leg ulcers (VLUs) treated with a combination of collagen, oxidized regenerated cellulose, and silver in conjunction with standard of care (SOC; intervention group) compared with SOC alone (control group). Standard of care included ADAPTIC nonadhering dressing (Acelity, San Antonio, Texas) and compression. DESIGN AND SETTING: Randomized controlled trial that followed patients in 3 US facilities for 12 weeks or until complete healing...
October 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28888006/chitosan-membrane-dressings-toughened-by-glycerol-to-load-antibacterial-drugs-for-wound-healing
#19
Ye Ma, Lian Xin, Huaping Tan, Ming Fan, Jianliang Li, Yang Jia, Zhonghua Ling, Yong Chen, Xiaohong Hu
Transparent and flexible chitosan-based membranes containing antibacterial drugs were prepared through a casting/solvent evaporation method from suspension of chitosan floccule. To enhance mechanical properties, glycerin was incorporated into the floccule suspension to conjugate chitosan as a plasticizer. The mechanism of membrane formation is attributed to inter- and intro-hydrogen bonding between chitosan and glycerol molecules. The results showed that incorporation of glycerol has a significant influence on the properties of the chitosan membranes...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28878170/nanosilver-silica-composite-prolonged-antibacterial-effects-and-bacterial-interaction-mechanisms-for-wound-dressings
#20
Dina A Mosselhy, Henrika Granbohm, Ulla Hynönen, Yanling Ge, Airi Palva, Katrina Nordström, Simo-Pekka Hannula
Infected superficial wounds were traditionally controlled by topical antibiotics until the emergence of antibiotic-resistant bacteria. Silver (Ag) is a kernel for alternative antibacterial agents to fight this resistance quandary. The present study demonstrates a method for immobilizing small-sized (~5 nm) silver nanoparticles on silica matrix to form a nanosilver-silica (Ag-SiO₂) composite and shows the prolonged antibacterial effects of the composite in vitro. The composite exhibited a rapid initial Ag release after 24 h and a slower leaching after 48 and 72 h and was effective against both methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli ( E ...
September 6, 2017: Nanomaterials
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