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https://www.readbyqxmd.com/read/27896875/disseminated-cobblestone-like-skin-lumps-in-a-newborn
#1
Z X Ren, H Q Jiang, L X Zhang, Q D Deng, J Y Zhang, X P Mu, J Yang
An newborn boy showed multiple skin lumps at birth. On examination, there were disseminated red cobblestone-like skin neoplasms, 5-30mm in diameter with hard serosanguineous crust, some were with scabs, over the scalp, face, trunk and extremities (Fig. 1A,B). The liver was 3 cm palpable below the costal margin. He was active and stable. The mother' prenatal investigation on antibodies of rubella, herpes simplex virus (HSV) and hepatitis B surface antigen were positive. The baby's antibodies for HAV, HBV, HCV, rubella, HSV, HIV and syphilis were negative...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27895906/respiratory-distress-associated-with-heterotopic-gastrointestinal-cysts-of-the-oral-cavity-a-case-report
#2
Marco Antonio Méndez Sáenz, Mario de Jesús Villegas González, Marco A Ponce Camacho, Lucia M Cavazos Cavazos, Bárbara Sáenz Ibarra, Blanca I Esquivel García, José Luis Treviño González
Heterotopic gastrointestinal cysts of the oral cavity are benign lesions usually discovered during infancy. Their pathogenesis is not very clear. They are rare congenital anomalies that result from remnants of foregut-derived epithelium in the head, neck, thorax or abdomen during embryonic development. The majority of these lesions occur in the anterior ventral surface of the tongue and extend to the floor of the mouth. They are confused clinically by surgeons in cases of head and neck masses in children as ranulas, dermoid and thyroglossal cysts, and lymphangioma...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27895847/efficacy-of-a-low-cost-bubble-cpap-system-in-treatment-of-respiratory-distress-in-a-neonatal-ward-in-malawi
#3
Kondwani Kawaza, Heather E Machen, Jocelyn Brown, Zondiwe Mwanza, Suzanne Iniguez, Al Gest, E O'Brian Smith, Maria Oden, Rebecca R Richards-Kortum, Elizabeth Molyneux
BACKGROUND: Respiratory failure is a leading cause of neonatal mortality in the developing world. Bubble continuous positive airway pressure (bCPAP) is a safe, effective intervention for infants with respiratory distress and is widely used in developed countries. Because of its high cost, bCPAP is not widely utilized in low-resource settings. We evaluated the performance of a new bCPAP system to treat severe respiratory distress in a low resource setting, comparing it to nasal oxygen therapy, the current standard of care...
September 2016: Malawi Medical Journal: the Journal of Medical Association of Malawi
https://www.readbyqxmd.com/read/27887680/emergency-video-telemedicine-consultation-for-newborn-resuscitations-the-mayo-clinic-experience
#4
Jennifer L Fang, Christopher A Collura, Robert V Johnson, Garth F Asay, William A Carey, Douglas P Derleth, Tara R Lang, Beth L Kreofsky, Christopher E Colby
OBJECTIVE: To describe the Mayo Clinic experience with emergency video telemedicine consultations for high-risk newborn deliveries. PATIENTS AND METHODS: From March 26, 2013, through December 31, 2015, the Division of Neonatal Medicine offered newborn telemedicine consultations to 6 health system sites. A wireless tablet running secure video conferencing software was used by the local care teams. Descriptive data were collected on all consultations. After each telemedicine consult, a survey was sent to the neonatologist and referring provider to assess the technology, teamwork, and user satisfaction...
November 10, 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27884070/association-of-sp-c-gene-codon-186-polymorphism-rs1124-and-risk-of-rds
#5
Neda Fatahi, Hosein Dalili, Majid Kalani, Nikoo Niknafs, Mamak Shariat, Javad Tavakkoly-Bazzaz, Elaheh Amini, Tahereh Esmaeilnia Shirvani, Amir Kamal Hardani, Roya Taheritafti, Nasrin Ghasemi-Fakhr, Mohsen Ghadami, Fatemeh Nayeri, Ali Rashidi-Nezhad
BACKGROUND: Respiratory distress syndrome (RDS) is a severe pulmonary disease that mainly affects preterm neonates. Surfactant-protein genes' polymorphisms have been mostly evaluated as the candidate contributors in genetics of RDS. However, the results are diverse in different populations. We aimed at investigating the association of rs1124 with RDS development. METHOD: Three hundred and thirty five preterm neonates were enrolled in a multicenter case-control study...
November 24, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27862664/-neonatal-outcomes-in-a-level-ii-regional-neonatal-intensive-care-unit
#6
Raid M R Umran, Asjad Al-Jammali
BACKGROUND: Improving the neonatal mortality is a challenge in developing countries like Iraq. Increasing demands and overload of maternity services can considerably limit the improvement in neonatal outcomes. We aimed to document the numbers, disease patterns and outcomes of admitted newborns and the improvement after implementing clinical protocols and to identify possible future target measures. METHOD: A descriptive study was conducted at neonatal intensive care unit (NICU) at a regional hospital from 2011 to 2013...
November 12, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27835691/surfactant-protein-a-and-b-gene-polymorphisms-and-risk-of-respiratory-distress-syndrome-in-late-preterm-neonates
#7
Maria-Eleni I Tsitoura, Eleana F Stavrou, Ioannis A Maraziotis, Kosmas Sarafidis, Aglaia Athanassiadou, Gabriel Dimitriou
BACKGROUND AND OBJECTIVES: Newborns delivered late-preterm (between 340/7 and 366/7 weeks of gestation) are at increased risk of respiratory distress syndrome (RDS). Polymorphisms within the surfactant protein (SP) A and B gene have been shown to predispose to RDS in preterm neonates. The aim of this study was to investigate whether specific SP-A and/or SP-B genetic variants are also associated with RDS in infants born late-preterm. METHODS: This prospective cross-sectional study included 56 late-preterm infants with and 60 without RDS...
2016: PloS One
https://www.readbyqxmd.com/read/27808058/-acute-post-partum-presentation-of-bochdalek-hernia-in-a-grown-up-woman
#8
Cecilie Dovey de la Cour, Biniam Teklay
Congenital diaphragmatic hernias are rare embryonic defects, mostly diagnosed in newborns with respiratory distress. The defect is often situated posterolaterally as a Bochdalek hernia. We report an unusual case of a 27-year old woman presenting with diffuse abdominal pain five days postpartum. An X-ray and a computed tomography displayed a herniation of the colon into the left chest cavity. Through converted open surgery, the 6 x 3 cm defect was repaired and the recovery was uneventful. Bochdalek hernias in adults may present as gastrointestinal emergencies and rapid diagnosis and operation are crucial...
October 31, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27799069/effects-of-ultrasound-pregnancy-dating-on-neonatal-morbidity-in-late-preterm-and-early-term-male-infants-a-register-based-cohort-study
#9
Merit Kullinger, Bengt Haglund, Helle Kieler, Alkistis Skalkidou
BACKGROUND: Assessing gestational age by ultrasound can introduce a systematic bias due to sex differences in early growth. METHODS: This cohort study included data on 1,314,602 births recorded in the Swedish Medical Birth Register. We compared rates of prematurity-related adverse outcomes in male infants born early term (gestational week 37-38) or late preterm (gestational week 35-36), in relation to female infants, between a time period when pregnancy dating was based on the last menstrual period (1973-1978), and a time period when ultrasound was used for pregnancy dating (1995-2010), in order to assess the method's influence on outcome by fetal sex...
October 31, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27796747/neonatal-dexamethasone-treatment-exacerbates-hypoxia-ischemia-induced-white-matter-injury
#10
Chia -Yu Yeh, Che-Ming Yeh, Ting-Hsuan Yu, Kan-Hsun Chang, Chiung-Chun Huang, Kuei-Sen Hsu
Dexamethasone, a synthetic glucocorticoid, has been widely used to prevent or ameliorate morbidity of chronic lung disease in preterm infants with respiratory distress syndrome. Despite its beneficial effect on neonatal lung function, growing concern has arisen about adverse effects of this clinical practice on fetal brain development. We demonstrated previously that neonatal dexamethasone (DEX) treatment may render the newborn brain to be more vulnerable to hypoxia/ischemia (HI)-induced gray matter injury...
October 28, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27789662/improved-neonatal-mortality-at-a-district-hospital-in-aweil-south-sudan
#11
Johanna Thomson, Myrto Schaefer, Belen Caminoa, David Kahindi, Northan Hurtado
Neonatal deaths comprise a growing proportion of global under-five mortality. However, data from the highest-burden areas is sparse. This descriptive retrospective study analyses the outcomes of all infants exiting the Médecins sans Frontières-managed neonatal unit in Aweil Hospital, rural South Sudan from 2011 to 2014. A total of 4268 patients were treated over 4 years, with annual admissions increasing from 687 to 1494. Overall mortality was 13.5% (n = 576), declining from 18.7% to 11.1% (p for trend <0...
October 27, 2016: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/27779696/microfloral-diversity-in-the-lower-respiratory-tracts-of-neonates-with-bacterial-infectious-pneumonia-combined-with-ventilator%C3%A2-associated-pneumonia
#12
Wei Lu, Jia-Lin Yu, Lu-Quan Li, Qi Lu, Zheng-Li Wang, Yun Pan
Bacterial infectious pneumonia is one of the major causes of mortality in neonates, particularly when the neonates suffer from ventilator‑associated pneumonia (VAP). However, the causes of pneumonia are difficult to define. Thus, the present study focused on understanding the diversity of microflora in the lower respiratory tract to elucidate the causes. The experimental groups comprised newborns who suffered from infectious pneumonia with or without VAP (IVAP and IP groups, respectively), whereas the control group comprised newborns who suffered from respiratory distress syndrome (RDS) without VAP (RDS group)...
October 25, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27774886/the-clinico-hematological-features-and-management-outcome-in-neonatal-malaria-a-nine-years-analysis-from-north-india
#13
Kriti Mohan
BACKGROUND: Malaria is an important cause of death and illness in children worldwide. Most cases of neonatal malaria are misdiagnosed because of the lack of specific symptoms and a general lack of awareness. Nothing much is known in literature about the haematological changes during malaria infection and outcome of disease in neonates. Neonatal malaria is an underdiagnosed entity. So this hospital based observational study aims to assess diagnostic features of neonatal malaria. METHODS: From August 2004 to August 2013, information of all slide positive for malaria cases aged 0 to 28 days admitted to our pediatric hospital was collected and analysed...
October 20, 2016: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/27749674/point-of-care-ultrasound-diagnosis-of-diaphragmatic-hernia-in-an-infant-with-respiratory-distress
#14
Jessica H Rankin, Marsha Elkhunovich, Dina Seif, Mikaela Chilstrom
Neonatal respiratory distress is an emergent condition with a wide differential diagnosis. A 12-day-old newborn presented to the emergency department in respiratory distress. Point-of-care ultrasound allowed clinicians to rapidly exclude cardiac disease and pneumothorax as possible causes of the patient's respiratory distress, and expedited the identification of congenital diaphragmatic hernia. The ultrasound findings and technique, epidemiology, pathophysiology, and radiological diagnosis of congenital diaphragmatic hernia are reviewed...
October 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27741189/prenatally-diagnosed-vasa-previa-a-single-institution-series-of-96-cases
#15
Val Catanzarite, Larry Cousins, Sean Daneshmand, Wade Schwendemann, Holly Casele, Joanna Adamczak, Tevy Tith, Ami Patel
OBJECTIVE: To describe outcomes for a large cohort of women with prenatally diagnosed vasa previa, determine the percentage in patients without risk factors, and compare delivery timing and indications for singletons and twins. METHODS: This was a retrospective case series of women with prenatally diagnosed vasa previa delivered at a single tertiary center over 12 years. Potential participants were identified using hospital records and perinatal databases. Patients were included if vasa previa was confirmed at delivery and by pathologic examination...
November 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27734990/interindividual-variability-in-the-expression-of-surfactant-protein-a-and-b-in-the-human-lung-during-development
#16
F Cau, E Pisu, C Gerosa, G Senes, F Ronchi, C Botta, E Di Felice, F Uda, V Marinelli, G Faa, V Fanos, C Moretti, D Fanni
The surfactant complex, thanks to its multiple actions including decrease of surface- tension and antimicrobial activity, plays a fundamental role in newborn survival, lowering the risk of respiratory distress syndrome. The aim of this work was to determine if the synthesis of two surfactant proteins (SP), SPA and pro-SPB, shows some inter-individual variability during lung development in the intrauterine life. Immunoreactivity for SPA and pro-SPB was investigated in the lungs of  40 subjects, including 15 fetuses, ranging from 14 to 22 weeks of gestation, and 25 neonates, from 24 to 41 weeks...
September 26, 2016: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/27733360/antenatal-corticosteroids-for-maturity-of-term-or-near-term-fetuses-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#17
Gabriele Saccone, Vincenzo Berghella
OBJECTIVE:  To evaluate the effectiveness of antenatal corticosteroids given at ≥34 weeks' gestation. DESIGN:  Systematic review with meta-analysis. DATA SOURCES:  Electronic databases were searched from their inception to February 2016. ELIGIBILITY CRITERIA FOR STUDY SELECTION:  Randomized clinical trials comparing antenatal corticosteroids with placebo or no treatment in women with a singleton pregnancy at ≥34 weeks' gestation...
October 12, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27648334/empedobacter-brevis-meningitis-in-a-neonate-a-very-rare-case-of-neonatal-meningitis-and-literature-review
#18
Deepak Sharma, Ankur Patel, Priyanka Soni, Pradeep Sharma, Basudev Gupta
Empedobacter brevis is gram-negative bacilli that belongs to Flavobacteriaceae family. It was previously known with name of Flavobacterium breve. The reservoir of these bacteria is soil, plants, water, food, hospital water sources, including incubators, sinks, faucets, tap water, hemodialysis systems, saline solutions, and other pharmaceutical solutions. We report a case of term female newborn, admitted with complaint of respiratory distress developing soon after birth and developed clinical features of sepsis at age of 92 hours of postnatal life...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27642489/neonatal-respiratory-distress-in-a-reference-neonatal-unit-in-cameroon-an-analysis-of-prevalence-predictors-etiologies-and-outcomes
#19
Joel Noutakdie Tochie, Simeon-Pierre Choukem, Regina Ndasi Langmia, Esther Barla, Paul Koki-Ndombo
INTRODUCTION: Neonatal respiratory distress (NRD) is a main cause of neonatal morbidity and mortality in developing countries. Early detection of its risk factors and early treatment of its etiologies are major challenges. However, few studies in developing countries have provided data needed to tackle it. We aimed to determine the prevalence, predictors, etiologies and outcome of NRD in a tertiary health care centre of Cameroon. METHODS: We analyzed the hospital files of all newborns admitted to the Neonatal unit of Douala General Hospital from 1(st) January 2011 to 28(th) February 2013...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27624140/major-determinants-of-survival-and-length-of-stay-in-the-neonatal-intensive-care-unit-of-newborns-from-women-with-premature-preterm-rupture-of-membranes
#20
Meryem Kurek Eken, Abdülhamit Tüten, Enis Özkaya, Güner Karatekin, Ateş Karateke
OBJECTIVE: To assess the predictors of outcome in terms of length of stay in the neonatal intensive care unit (NICU) and survival of neonates from women with preterm premature rupture of membranes (PPROM). METHODS: A population-based retrospective study including three hundred thirty-one singleton pregnant women with PPROM at 24-34 gestational weeks between January 2013 and December 2015 was conducted. Gestational age at delivery, birth weight, route of delivery, newborn gender, maternal age,oligohydramnios, premature retinopathy (ROP), necrotising enterocolitis (NEC), sepsis, fetal growth retardation (FGR), intracranial hemorrhagia (ICH), bronchopulmonary dysplasia (BPD), respiratory distress syndrome (RDS), primary pulmonary hypertension (PPH), congenital cardiac disease (CCD), patent ductus arteriosus (PDA), use of cortisol (betamethasone) and maternal complications including gestational diabetes, preeclampsia, and chorioamnionitis were used to predict neonatal outcomes in terms of length of stay in the NICU and survival...
September 14, 2016: Journal of Maternal-fetal & Neonatal Medicine
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