keyword
MENU ▼
Read by QxMD icon Read
search

NPWT

keyword
https://www.readbyqxmd.com/read/28817237/dysregulation-of-wound-healing-mechanisms-in-diabetes-and-the-importance-of-negative-pressure-wound-therapy-npwt
#1
Mogher Khamaisi, Sarit Balanson
Diabetes is a serious disease with severe side effects and comorbidities. Diabetic foot with its chronic non-healing ulcers, or diabetic food ulcers (DFU) as they are commonly called, can be devastating, even leading to amputation. Many therapies exist to assist and improve wound healing. One exciting discovery is the use of negative pressure wound therapy (NPWT) as an adjunct to standard treatment. Few studies have substantively explored the molecular mechanisms of NPWT and why we see improved wound healing, a concept that demands more research...
August 17, 2017: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/28816717/comparison-of-negative-pressure-wound-therapy-and-conventional-therapy-for-cranial-bone-exposed-wounds-in-rabbits
#2
Lin Chen, Guorui Li, Sha Liu, Xianjie Ma, Xueyong Li, Yingjun Su, Shuzhong Guo
BACKGROUND: Bone-exposed wounds with intact or defected periosteum are difficult to heal. To provide relevant experimental evidence for guidance of clinical therapy, we established a rabbit model to compare the efficacies of negative pressure wound therapy (NPWT) and conventional guaze dressing therapy on the healing of cranial bone-exposed wounds. METHODS: Full-thickness excisional circular wounds of 2.0 cm in diameter with exposed bones covered with or without periosteum were created at the parietal regions in 88 rabbits that were further randomly divided into the following treatment groups: periosteum-intact wounds treated with conventional vaseline gauze dressings (P + Control group), periosteum-intact wounds treated with NPWT (P + NPWT group), periosteum-lacking wounds treated with conventional vaseline gauze dressings (P-Control group), and periosteum-lacking wounds treated with NPWT (P-NPWT group)...
August 14, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28797553/negative-pressure-wound-therapy
#3
REVIEW
Bryden J Stanley
Open wounds are regularly addressed in veterinary medicine and can be challenging to manage, especially when there is significant loss of full-thickness skin. Traditional wound dressings are being replaced by modern synthetic materials, biologic wound dressings, and mechanical technologies to augment healing. Negative pressure wound therapy (NPWT) is one of the most successful mechanical adjuncts to wound healing. Experience with NPWT in veterinary medicine is not as extensive as in human medicine but reports have been positive...
August 7, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28795891/experience-using-closed-incision-negative-pressure-wound-therapy-in-sternotomy-patients
#4
B Philip, P McCluskey, J Hinchion
OBJECTIVE: Postoperative delayed wound healing, surgical site infections (SSIs), and other wound complications are associated with increased morbidity and health-care costs. In cardiothoracic surgery, wound complications can have life-threatening consequences. In recent years, negative pressure wound therapy (NPWT) has been applied over closed surgical incisions to help reduce tension and protect from external contamination. We report our initial experiences using a closed incision negative pressure therapy (ciNPT) over clean, closed sternotomy incisions at an Irish tertiary referral centre...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28795884/results-of-directly-applied-activated-carbon-cloth-in-chronic-wounds-a-preliminary-study
#5
H S Scheer, M Kaiser, U Zingg
OBJECTIVE: Activated carbon (AC) has been used in wound therapy as an active substance inside dressings. Applying AC directly on a wound is a new concept. The aim of this study was to analyse the outcomes of chronic wounds which were managed with directly applied activated carbon knitted cloth (ACC, Zorflex) in Swiss patients. METHOD: A retrospective analysis of the records of all patients with chronic wounds treated with ACC between 1 October 2013 and 31 December 2015 in an outpatient wound clinic...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28792821/negative-pressure-wound-therapy-and-nurse-education
#6
Amy Cray
BACKGROUND: there can be serious consequences for patients if negative pressure wound therapy (NPWT) is performed incorrectly and patient safety must be paramount. The existing literature was found to mainly concentrate on the use of the technology from the patient perspective. This article examines the opinions of nurses who apply the therapy. METHOD: five staff nurses from different areas with differing experience levels were interviewed in a semi-structured manner...
August 10, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28763910/-influence-of-different-inner-dressings-in-negative-pressure-wound-therapy-on-escharectomy-wound-of-full-thickness-burn-rabbits
#7
J H Lin, J Chen, D J Xue, W X Huang, G L Su
Objective: To explore the influence of different inner dressings in negative-pressure wound therapy (NPWT) on escharectomy wound of full-thickness burn rabbits. Methods: Eighteen Japanese white rabbits were inflicted with full-thickness burn on unilateral back. They were divided into polymer dressing group (PD), biological dressing group (BD), and silver biological dressing group (SBD), according to the random number table, with 6 rabbits in each group. On 3 days post burn, the wounds were performed with escharectomy, and then wounds of rabbits in group PD were covered with polyurethane foam...
July 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28759427/negative-pressure-wound-therapy-for-patients-with-complex-abdominal-wounds
#8
Zhi Wang, Ming Bai, Xiao Long, Ru Zhao, Xiaojun Wang
The combination of open abdominal wounds and intra-abdominal infections is challenging to treat and often results in critical illness associated with high mortality. OBJECTIVE: The aim of this study is to evaluate the feasibility of using negative pressure wound therapy (NPWT) to manage complex abdominal wounds and summarize relevant treatment experiences. MATERIALS AND METHODS: A retrospective analysis of records from April 2012 to May 2015 identified 13 hospitalized patients with open abdominal wounds complicated by intra-abdominal infections...
July 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28751990/dermal-substitutes-use-in-reconstructive-surgery-for-skin-tumors-a-single-center-experience
#9
Mariane Campagnari, Andrea S Jafelicci, Helio A Carneiro, Eduard R Brechtbühl, Eduardo Bertolli, João P Duprat Neto
Reconstructive surgery following skin tumor resection can be challenging. Treatment options after removing the tumor are skin grafting, local pedicled and axial flaps, or microsurgery for complex and extensive wounds correction. Recently, the use of dermal substitutes has been extended to reconstructive surgery in cutaneous oncology. Objectives. To report both a single-center experience using dermal substitutes in reconstructive surgery for skin malignancies and reconstructive surgery's outcomes. Methods and Results...
2017: International Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28742785/an-effective-negative-pressure-wound-therapy-1-compatible-local-antibiotic-delivery-device
#10
Ben C C Rand, Joseph C Wenke
OBJECTIVES: The current clinical standard for local antibiotic depot is polymethylmethacrylate (PMMA) beads. Unfortunately, these are not ideal and negative pressure wound therapy (NPWT) reduces their limited effectiveness. Recently, a chitosan sponge has been shown to be an effective carrier of antibiotics. Since it acts as a delivery vehicle with increased wound contact area instead of an antibiotic depot, it may be more effective. The objectives of this study are to determine if 1) a chitosan sponge would be more effective than PMMA beads as a local antibiotic delivery device and 2) the chitosan sponge remains an effective method of delivery when used in conjunction with NPWT...
July 24, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28732537/negative-pressure-wound-therapy-versus-modified-barker-vacuum-pack-as-temporary-abdominal-closure-technique-for-open-abdomen-management-a-four-year-experience
#11
Giulia Montori, Niccolò Allievi, Federico Coccolini, Leonardo Solaini, Luca Campanati, Marco Ceresoli, Paola Fugazzola, Roberto Manfredi, Stefano Magnone, Matteo Tomasoni, Luca Ansaloni
BACKGROUND: We reviewed our experience with patients presenting with trauma and peritonitis who underwent an open abdomen (OA) procedure, and compared outcomes between Negative Pressure Wound Therapy (NPWT) and a modified Barker Vacuum Pack (mBVP) technique. METHODS: In this descriptive study, we retrospectively analyzed data regarding all patients who underwent OA for intra-abdominal sepsis or abdominal trauma at our Centre from January 2012 to December 2015. Demographic data, co-morbidities, indications to surgery, intra-operative details and Björck classification grade were considered...
July 21, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28730321/age-and-dressing-type-as-independent-predictors-of-post-operative-infection-in-patients-with-acute-compartment-syndrome-of-the-lower-leg
#12
Mark E Hake, Jordan Etscheidt, Vivek P Chadayammuri, Jacob M Kirsch, Cyril Mauffrey
PURPOSE: The purpose of this study was to determine independent factors, including timing of fasciotomy, that confer an increased risk of post-operative surgical site infection (SSI) in patients presenting with acute compartment syndrome (ACS) of the lower extremity. METHODS: A retrospective analysis was performed on a consecutive cohort of 53 adult patients requiring fasciotomy for lower-extremity fractures complicated by ACS presenting to a single Level I trauma center over a seven-year study period...
July 20, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28728326/the-role-of-negative-pressure-wound-therapy-in-latissimus-dorsi-flap-donor-site-seroma-prevention-a-cohort-study
#13
Apichai Angspatt, Thana Laopiyasakul, Pornthep Pungrasmi, Poonpissamai Suwajo
BACKGROUND: Donor site seroma is the most common complication after latissimus dorsi (LD) flap harvest. This study aimed to evaluate the efficacy of negative-pressure wound therapy (NPWT) in preventing donor site seroma formation after the harvest of an LD flap for breast reconstruction. METHODS: In this prospective matched-pair study, 40 patients in whom an LD flap was harvested for breast reconstruction were enrolled. NPWT was used in 20 patients, and in a control group composed of another 20 patients, the conventional donor site dressing technique was used...
July 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28717912/management-of-the-open-abdomen-after-liver-transplantation
#14
Christian Hobeika, Marc-Antoine Allard, Petru-Octav Bucur, Salima Naili, Antonio Sa Cunha, Daniel Cherqui, Denis Castaing, René Adam, Eric Vibert
INTRODUCTION: The optimal management of the open abdomen (OA) after liver transplantation (LT) is unclear. The negative pressure wound therapy (NPWT) has been shown to be safe and can increase the chance for early fascial closure in trauma or septic patients. However, little data are available on the specific setting of LT. We aimed to report our experience of OA after LT, marked by the recent use of NPWT. METHODS: All patients with postponed wall closure after LT, from 2002 to 2014, in a single institution were included and retrospectively analyzed...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28704154/the-use-of-a-micropore-particle-technology-in-the-treatment-of-acute-wounds
#15
E Ryan
OBJECTIVE: A clinical audit was performed to evaluate whether Acapsil micropore particle technology (MPPT) powder could improve the management of acute wounds to heal by secondary intention. METHOD: Wounds, which could be characterised as sloughy, wet and probably infected, normally managed by debridement followed by negative pressure wound therapy (NPWT), were included in the evaluation. The MPPT powder was applied topically to the wound surface either once daily or on alternate days, with each wound receiving a total of two to five applications...
July 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28698756/treatment-of-decubitis-ulcer-stage-iv-in-the-patient-with-polytrauma-and-vertical-share-pelvic-fracture-diagnosed-entherocollitis-and-deep-wound-infection-with-clostridium-difficile-with-combined-negative-pressure-wound-therapy-npwt-and-faecal-management-system
#16
Slavcho Stojmenski, Igor Merdzanovski, Andrej Gavrilovski, Sofija Pejkova, Gjorge Dzokic, Smilja Tudzarova
AIM: The aim of this paper was to present a case with the successful treatment of decubitis ulcer stage IV in the patient with polytrauma and vertical share pelvic fracture and diagnosed entherocollitis combined with deep wound infection with Clostridium difficile treated with combined Negative Pressure Wound Therapy (NPWT) and faecal management system. CASE REPORT: Patient D.S.1967 treated on Traumatology Clinic after tentamen suicide on 9.2.2015 with diagnosis: brain contusion; contusion of thoracal space; vertical share pelvic fracture; open fracture type II of the right calcaneus; fracture of the left calcaneus; fracture on the typical place of the left radius; fracture of the right radius with dislocation...
June 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28665497/protein-and-modified-vaccinia-virus-ankara-based-influenza-virus-nucleoprotein-vaccines-are-differentially-immunogenic-in-balb-c-mice
#17
Arwen F Altenburg, Sofia E Magnusson, Fons Bosman, Linda Stertman, Rory D de Vries, Guus F Rimmelzwaan
Because of the high variability of seasonal influenza viruses and the eminent threat of influenza viruses with pandemic potential, there is great interest in the development of vaccines that induce broadly protective immunity. Most likely, broadly protective influenza vaccines are based on conserved proteins, such as nucleoprotein (NP). NP is a vaccine target of interest since it has been shown to induce cross-reactive antibody and T cell responses. Here we tested and compared various NP-based vaccine preparations for their capacity to induce humoral and cellular immune responses to influenza virus NP...
June 30, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/28657898/negative-pressure-wound-therapy-for-a-complicated-abdominal-laparotomy-in-neonatal-necrotizing-enterocolitis-a-case-report
#18
Miriam García Gonzalez, Isabel Casal Beloy, Alba Gómez Dovigo, Lorena Miguez Fortes, Teresa Dargallo Carbonell, Salvador Pita-Fernández, Jesús Caramés Bouzán
Necrotizing enterocolitis (NEC) is the most common surgical emergency in neonatal intensive care units, and patients who require surgery have high mortality and morbidity rates. The utility of negative pressure in the management of adults with complicated abdominal wounds has been documented, but there are few reports describing the use of negative pressure wound therapy (NPWT) in children or following neonatal surgery. The case of a 6 day old, 5-weeks premature neonate with NEC is presented. An exploratory midline laparotomy was performed on day 3 of life owing to rectal bleeding and abdominal distension that did not respond to gastric decompression, bowel rest, and intravenous antibiotics...
June 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28654850/wound-management-with-negative-pressure-wound-therapy-in-postoperative-infection-after-open-reconstruction-of-chronic-achilles-tendon-rupture
#19
Isaku Saku, Shotaro Kanda, Toshihiro Saito, Takashi Fukushima, Toru Akiyama
INTRODUCTION: Deep infection after reconstruction of chronic Achilles tendon rupture is a major and intractable complication. CASE REPORT: We report a case of late deep infection following a surgery for chronic Achilles tendon rupture, and its simple and successful treatment with negative pressure wound therapy (NPWT). Six months following the reconstruction of chronic Achilles tendon rupture, a deep infection developed and reconstructed part of the tendon ruptured again...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28652788/economic-and-organizational-sustainability-of-a-negative-pressure-portable-device-for-the-prevention-of-surgical-site-complications
#20
Emanuela Foglia, Lucrezia Ferrario, Elisabetta Garagiola, Giuseppe Signoriello, Gianluca Pellino, Davide Croce, Silvestro Canonico
PURPOSE: Surgical-site complications (SSCs) affect patients' clinical pathway, prolonging their hospitalization and incrementing their management costs. The present study aimed to assess the economic and organizational implications of a portable device for negative-pressure wound therapy (NPWT) implementation, compared with the administration of pharmacological therapies alone for preventing surgical complications in patients undergoing general, cardiac, obstetrical-gynecological, or orthopedic surgical procedures...
2017: ClinicoEconomics and Outcomes Research: CEOR
keyword
keyword
4068
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"