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https://www.readbyqxmd.com/read/28108482/inhibition-of-prolyl-4-hydroxylase-decreases-muscle-fibrosis-following-chronic-rotator-cuff-tear
#1
J P Gumucio, M D Flood, A Bedi, H F Kramer, A J Russell, C L Mendias
OBJECTIVES: Rotator cuff tears are among the most frequent upper extremity injuries. Current treatment strategies do not address the poor quality of the muscle and tendon following chronic rotator cuff tears. Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor that activates many genes that are important in skeletal muscle regeneration. HIF-1α is inhibited under normal physiological conditions by the HIF prolyl 4-hydroxylases (PHDs). In this study, we used a pharmacological PHD inhibitor, GSK1120360A, to enhance the activity of HIF-1α following the repair of a chronic cuff tear, and measured muscle fibre contractility, fibrosis, gene expression, and enthesis mechanics...
January 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28101634/is-the-arthroscopic-suture-bridge-technique-suitable-for-full-thickness-rotator-cuff-tears-of-any-size
#2
Sung Hyun Lee, Jeong Woo Kim, Tae Kyun Kim, Seok Hyun Kweon, Hong Je Kang, Se Jin Kim, Jin Sung Park
PURPOSE: The purpose of this study was to compare functional outcomes and tendon integrity between the suture bridge and modified tension band techniques for arthroscopic rotator cuff repair. METHODS: A consecutive series of 128 patients who underwent the modified tension band (MTB group; 69 patients) and suture bridge (SB group; 59 patients) techniques were enrolled. The pain visual analogue scale (VAS), Constant, and American Shoulder and Elbow Surgeons (ASES) scores were determined preoperatively and at the final follow-up...
January 18, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28093618/mri-assessment-of-calf-injuries-in-australian-football-league-players-findings-that-influence-return-to-play
#3
George Waterworth, Sara Wein, Alexandra Gorelik, Andrew H Rotstein
OBJECTIVE: Calf muscle strains have become increasingly prevalent in recent seasons of the Australian Football League (AFL) and represent a significant cause of time lost from competition. The purpose of this study was to examine the association between MRI features of calf muscle strains and games missed and to thereby identify parameters that are of prognostic value. MATERIALS AND METHODS: A retrospective analysis of MRI scans of AFL players with calf strains referred to a musculoskeletal radiology clinic over a 5-year period (2008-2012) was performed...
January 16, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28089257/the-natural-course-of-nonoperatively-treated-rotator-cuff-tears-an-8-8-year-follow-up-of-tear-anatomy-and-clinical-outcome-in-49-patients
#4
Stefan Moosmayer, Anne V Gärtner, Rana Tariq
BACKGROUND: The natural course of nonoperatively treated rotator cuff tears is not fully understood. We explored the long-term development of tear anatomy and assessed functional outcomes. METHODS: Eighty-nine small to medium-sized full-thickness tears of the rotator cuff, all primarily treated by physiotherapy, were identified retrospectively. Twenty-three tears needed surgical treatment later on, and 17 patients were unable to meet for follow-up. The remaining 49 still unrepaired tears were re-examined after 8...
January 12, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28087164/anatomic-study-and-electromyographic-analysis-of-the-teres-minor-muscle
#5
Junichiro Hamada, Akimoto Nimura, Kunio Yoshizaki, Keiichi Akita
BACKGROUND: The teres minor muscle is a focused topic on the treatment of massive rotator cuff tears and reverse total shoulder arthroplasty. Its precise anatomy and function have not been completely investigated. The purposes of this study were to anatomically investigate the muscle and analyze electromyographic (EMG) activities during shoulder motion. METHODS: This anatomic study used 20 shoulders from deceased donors (mean age, 75.0 years). EMG data were recorded from 10 healthy volunteers (mean age, 21...
January 10, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28076015/us-and-mr-imaging-of-pectoralis-major-injuries
#6
Yauk K Lee, Matt R Skalski, Eric A White, Anderanik Tomasian, Diane D Phan, Dakshesh B Patel, George R Matcuk, Aaron J Schein
During the past 2 decades, the frequency of pectoralis major muscle injuries has increased in association with the increased popularity of bench press exercises. Injury of the pectoralis major can occur at the muscle origin, muscle belly, musculotendinous junction, intratendinous region, and/or humeral insertion-with or without bone avulsion. The extent of the tendon injury ranges from partial to complete tears. Treatment may be surgical or conservative, depending on the clinical scenario and anatomic characteristics of the injury...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28072595/fluoroquinolone-associated-muscle-tear-and-hematoma-a-case-report
#7
Ghulam Murtaza, Boonphiphop Boonpheng
No abstract text is available yet for this article.
December 28, 2016: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28070203/a-pilot-observational-study-on-magnesium-and-calcium-imbalance-in-elderly-patients-with-acute-aortic-dissection
#8
E Vianello, E Dozio, A Barassi, G Sammarco, L Tacchini, M M Marrocco-Trischitta, S Trimarchi, M M Corsi Romanelli
BACKGROUND: Magnesium (Mg) and calcium (Ca) are the principal essential elements involved in endothelial cell homeostasis. Extracellular changes in the levels of either alter endothelial contraction and dilatation. Consequently Mg and Ca imbalance is associated with a high risk of endothelial dysfunction, the main process observed during acute aortic dissection (AAD); in this clinical condition, which mainly affects elderly men, smooth muscle cell alterations lead to intimal tears, creating a false new lumen in the media of the aorta...
2017: Immunity & Ageing: I & A
https://www.readbyqxmd.com/read/28070148/comparison-of-the-epidemiology-and-outcomes-of-traumatic-and-nontraumatic-rotator-cuff-tears
#9
Takeshi Teratani
OBJECTIVE: The purpose of this study was to investigate the differences in the epidemiology and outcomes of traumatic and nontraumatic rotator cuff tears. METHODS: Thirty-three patients with traumatic and 46 with nontraumatic rotator cuff tears were included. RESULTS: The rate of injury to the long head of the biceps was significantly higher in the traumatic group. Preoperative active forward elevation was significantly lower in the traumatic group...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28066748/the-use-of-platelet-rich-plasma-to-augment-conservative-and-surgical-treatment-of-hip-and-pelvic-disorders
#10
REVIEW
Matthew J Kraeutler, Tigran Garabekyan, Omer Mei-Dan
BACKGROUND: In recent years, platelet-rich plasma (PRP) has gained popularity within the orthopaedic community as a treatment modality to enhance tissue healing. PURPOSE: This review aims to concisely present the current indications for PRP injections in the treatment of hip and pelvic pathologies and to describe some novel applications for PRP which have not yet been reported in the literature. METHODS: We reviewed the literature on the non-operative and operative indications for PRP in the treatment of hip and pelvic pathologies...
July 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28043853/the-biology-of-rotator-cuff-healing
#11
REVIEW
M-A Zumstein, A Lädermann, S Raniga, M-O Schär
Despite advances in surgical reconstruction of chronic rotator cuff (RC) tears leading to improved clinical outcomes, failure rates of 13-94% have been reported. Reasons for this rather high failure rate include compromised healing at the bone-tendon interface, as well as the musculo-tendinous changes that occur after RC tears, namely retraction and muscle atrophy, as well as fatty infiltration. Significant research efforts have focused on gaining a better understanding of these pathological changes in order to design effective therapeutic solutions...
December 30, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28031188/mri-appearance-does-not-change-in-the-first-7-days-after-acute-hamstring-injury-a-prospective-study
#12
Arnlaug Wangensteen, Roald Bahr, Robbart Van Linschoten, Emad Almusa, Rodney Whiteley, Erik Witvrouw, Johannes L Tol
BACKGROUND: The optimal timing of MRI following acute hamstring injury is not known and is mainly based on expert opinions. AIMS: To describe the day-to-day changes in the extent of oedema and investigate the optimal timing for detection of fibre disruption on MRI following acute hamstring injuries. STUDY DESIGN: Prospective, descriptive study. METHODS: We performed standardised MRI (1.5T) ≤1 day after injury in male athletes with acute hamstring injury...
December 28, 2016: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28027607/third-or-fourth-degree-intrapartum-anal-sphincter-tears-are-associated-with-levator-ani-avulsion-in-primiparas
#13
Dan V Valsky, Sarah M Cohen, Michal Lipschuetz, Drorith Hochner-Celnikier, Hagit Daum, Itai Yagel, Simcha Yagel
OBJECTIVES: We evaluated primiparous women with clinically diagnosed third- and fourth-degree and anal sphincter tears, to evaluate the rate of levator ani muscle injury compared to primiparous women without sphincter tears. METHODS: Primiparous women delivering in our maternity ward with intrapartum diagnoses of third- or fourth-degree anal sphincter tears, repaired by the overlapping technique, were recruited to undergo 3-dimensional transperineal sonography of the pelvic floor anatomy, including the anterior and posterior compartments...
April 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28008460/treatment-of-tear-trough-deformity-fat-repositioning-versus-autologous-fat-grafting
#14
Chiao-Yun Chiu, Yi-Chen Shen, Qing-Fang Zhao, Fu-Liang Hong, Jing-Hong Xu
BACKGROUND: Fat-preserving lower blepharoplasty techniques and filling techniques using autologous or non-autologous materials are increasingly used to treat tear trough deformity. However, there has been no definitive comparison of the results of fat repositioning versus autologous fat grafting for this condition. The authors used statistical analysis to compare the results of the two methods. METHODS: From October 2013 to September 2015, a total of 101 patients, aged 20-43 years, underwent fat repositioning or autologous fat grafting in our department...
December 23, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28005092/preservation-of-the-anterior-cruciate-ligament-a-treatment-algorithm-based-on-tear-location-and-tissue-quality
#15
Jelle P van der List, Gregory S DiFelice
The gold standard of anterior cruciate ligament (ACL) injuries is currently single-bundle autograft reconstruction. However, many disadvantages of reconstructive surgery exist, such as: anterior knee pain, muscle atrophy, and loss of range of motion. In addition, native kinematics are not restored, and osteoarthritis is not prevented. Finally, revision surgery, if necessary, can be problematic due to tunnel widening, tunnel malpositioning, and preexisting hardware. Ligament preservation includes preservation of native tissues in order to optimize the biologic aspects, while decreasing the invasive nature of reconstructive surgery...
November 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/27989344/a-proximal-fibularis-brevis-muscle-is-associated-with-longitudinal-split-tendons-a-cadaveric-study
#16
Stephen N Housley, James E Lewis, Deon L Thompson, Gordon Warren
The anomalous distal musculotendinous junction of the fibularis brevis muscle has been hypothesized to contribute to the development of longitudinal fibularis brevis tendon tears. Specifically, the mass effect of the low-lying fibularis brevis muscle belly was thought to increase the pressure on the superior peroneal retinaculum and increase the probability of fibularis brevis tendon subluxation. A more recent examination of the fibularis brevis tendon junction found, contrary to this hypothesis, a statistically significant association between an anomalous proximal musculotendinous junction and the prevalence of longitudinal split tears...
January 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/27984691/-iliacus-muscle-injury-caused-by-inadequate-exercise
#17
J Magaña-Reyes, L G Domínguez-Gasca, A García-Luna, L G Domínguez-Carrillo
BACKGROUND: Traumatic iliacus muscle injury is rare; it is usually caused by trauma or intense exercise involving the pelvic girdle; it can produce a hematoma with femoral nerve neuropathy. Spontaneous muscle hematomas occur in patients with coagulation disorders. CLINICAL CASE: A 45-year-old male with 18 days of evolution, with an intense pain in the right buttock, groin and iliac fossa, with an inability for hip flexion and ambulation caused by inadequate exercise (supine double leg lifts)...
May 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27964874/differences-in-fatty-degeneration-of-rotator-cuff-muscles-at-different-sites-as-quantified-by-t2-mapping
#18
Yuki Iijima, Keisuke Matsuki, Shota Hoshika, Yusuke Ueda, Kazutomo Onishi, Morihito Tokai, Norimasa Takahashi, Hiroyuki Sugaya, Kazuhiko Dougo, Atsuya Watanabe
BACKGROUND: Fatty degeneration of the cuff muscles is usually evaluated at the Y-view in oblique sagittal images. It was recently proposed that muscle shift after repair may influence the fatty degeneration values, and the evaluation of the muscles at a more medial site was recommended. However, the differences in muscle quality in accord with measurement sites have been unclear. Here we evaluated differences in fatty degeneration of the rotator cuff muscles measured quantitatively at different sites, using T2 mapping...
December 10, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/27916191/the-rotator-cuff-and-the-superior-capsule-why-we-need-both
#19
Christopher R Adams, Angelica M DeMartino, George Rego, Patrick J Denard, Stephen S Burkhart
Tears of the rotator cuff are frequent. An estimated 250,000 to 500,000 repairs are performed annually in the United States. Rotator cuff repairs have been successful despite fatty infiltration and atrophy of the rotator cuff muscles. Although the emphasis in rotator cuff repair has historically focused on re-establishing the tendon attachment, there is growing interest in and understanding of the role of the superior capsule. The superior capsule is attached to the undersurface of the supraspinatus and infraspinatus muscle-tendon units, and it resists superior translation of the humeral head...
December 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27914845/does-magnetic-resonance-imaging-appearance-of-supraspinatus-muscle-atrophy-change-after-repairing-rotator-cuff-tears
#20
Sang-Hoon Lhee, Anant Kumar Singh, Do Young Lee
BACKGROUND: This study was conducted to determine whether supraspinatus muscle atrophy appearance changes after arthroscopic rotator cuff repair and to quantify the change in appearance on magnetic resonance imaging (MRI), if any, based on age and tendon retraction. METHODS: We retrospectively reviewed patients who underwent arthroscopic rotator cuff repair and considered only 209 patients who had both preoperative and immediate postoperative MRI. Patients were grouped by age <60 years and >60 years...
November 30, 2016: Journal of Shoulder and Elbow Surgery
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