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https://www.readbyqxmd.com/read/28280296/discharge-and-infection-in-retinoblastoma-post-enucleation-sockets
#1
Daphne L Mourits, Dyonne T Hartong, Andries E Budding, Machteld I Bosscha, H Stevie Tan, Annette C Moll
PURPOSE: To investigate the causes and treatment options for socket discharge and infection in patients enucleated for retinoblastoma (Rb). METHODS: A questionnaire was filled out by (parents of) ocular prosthesis-wearing patients with a history of enucleation as treatment for Rb. We collected data on patients' characteristics, cleaning habits of the prosthesis, frequency of socket irritation, discharge, and infection, and use of antibiotics. With ordinal logistic regression analysis, factors related to the outcome parameters (frequency of irritation, mucoid and purulent discharge) were identified...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28273165/transcriptome-profiling-of-influenza-a-virus-infected-lung-epithelial-a549-cells-with-lariciresinol-4-%C3%AE-d-glucopyranoside-treatment
#2
Beixian Zhou, Jing Li, Xiaoli Liang, Zifeng Yang, Zhihong Jiang
The influenza A virus is an acute contagious pathogen that affects the human respiratory system and can cause severe lung disease and even death. Lariciresinol-4-β-D-glucopyranoside is a lignan that is extracted from Isatis indigotica, which is a medicinal herb plant that was commonly applied to treat infections, the common cold, fever and inflammatory diseases. Our previous study demonstrated that lariciresinol-4-β-D-glucopyranoside possesses anti-viral and anti-inflammatory properties. However, the comprehensive and detailed mechanisms that underlie the effect of lariciresinol-4-β-D-glucopyranoside interventions against influenza virus infection remain to be elucidated...
2017: PloS One
https://www.readbyqxmd.com/read/28258279/management-of-respiratory-tract-infections-in-young-children-a-qualitative-study-of-primary-care-providers-perspectives
#3
Ruby Biezen, Bianca Brijnath, Danilla Grando, Danielle Mazza
Respiratory tract infections in young children are the most common cause of general practice visits in Australia. Despite the availability of clinical practice guidelines, the treatment and management of respiratory tract infections in young children is inconsistent. The aim of the study was to explore the management of respiratory tract infections in young children from a multi-disciplinary perspective using across-sectional qualitative research design based on the theoretical domains framework and the Capability, Opportunity and Motivation-B model...
December 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28256356/intensive-speech-and-language-therapy-in-patients-with-chronic-aphasia-after-stroke-a-randomised-open-label-blinded-endpoint-controlled-trial-in-a-health-care-setting
#4
Caterina Breitenstein, Tanja Grewe, Agnes Flöel, Wolfram Ziegler, Luise Springer, Peter Martus, Walter Huber, Klaus Willmes, E Bernd Ringelstein, Karl Georg Haeusler, Stefanie Abel, Ralf Glindemann, Frank Domahs, Frank Regenbrecht, Klaus-Jürgen Schlenck, Marion Thomas, Hellmuth Obrig, Ernst de Langen, Roman Rocker, Franziska Wigbers, Christina Rühmkorf, Indra Hempen, Jonathan List, Annette Baumgaertner
BACKGROUND: Treatment guidelines for aphasia recommend intensive speech and language therapy for chronic (≥6 months) aphasia after stroke, but large-scale, class 1 randomised controlled trials on treatment effectiveness are scarce. We aimed to examine whether 3 weeks of intensive speech and language therapy under routine clinical conditions improved verbal communication in daily-life situations in people with chronic aphasia after stroke. METHODS: In this multicentre, parallel group, superiority, open-label, blinded-endpoint, randomised controlled trial, patients aged 70 years or younger with aphasia after stroke lasting for 6 months or more were recruited from 19 inpatient or outpatient rehabilitation centres in Germany...
March 1, 2017: Lancet
https://www.readbyqxmd.com/read/28249303/clinical-parameters-following-multiple-oral-dose-administration-of-a-standardized-andrographis-paniculata-capsule-in-healthy-thai-subjects
#5
Tawit Suriyo, Nanthanit Pholphana, Teerapat Ungtrakul, Nuchanart Rangkadilok, Duangchit Panomvana, Apinya Thiantanawat, Wanwisa Pongpun, Jutamaad Satayavivad
Andrographis paniculata has been widely used in Scandinavian and Asian counties for the treatment of the common cold, fever, and noninfectious diarrhea. The present study was carried out to investigate the physiological effects of short-term multiple dose administration of a standardized A. paniculata capsule used for treatment of the common cold and uncomplicated upper respiratory tract infections, including blood pressure, electrocardiogram, blood chemistry, hematological profiles, urinalysis, and blood coagulation in healthy Thai subjects...
March 1, 2017: Planta Medica
https://www.readbyqxmd.com/read/28238227/hopes-and-challenges-for-the-common-cold
#6
EDITORIAL
Richard A Stein
No abstract text is available yet for this article.
February 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28228588/investigation-of-the-role-of-protein-kinase-d-in-human-rhinovirus-replication
#7
Anabel Guedán, Dawid Swieboda, Mark Charles, Marie Toussaint, Sebastian L Johnston, Amin Asfor, Anusha Panjwani, Tobias J Tuthill, Henry Danahay, Tony Raynham, Aurelie Mousnier, Roberto Solari
Picornavirus replication is known to cause extensive remodelling of Golgi and endoplasmic reticulum membranes and a number of the host proteins involved in the viral replication complex have been identified, including oxysterol binding protein (OSBP) and phosphatidylinositol 4-kinase III beta (PI4KB). Since both OSBP and PI4KB are substrates for protein kinase D (PKD) and PKD is known to be involved in the control of Golgi vesicular and lipid transport, we hypothesised that PKD played a role in viral replication...
February 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28224096/off-label-use-of-sulfur-hexafluoride-in-voiding-urosonography-for-diagnosis-of-vesicoureteral-reflux-in-children-a-survey-on-adverse-events
#8
Alexander Sauer, Clemens Wirth, Isabel Platzer, Henning Neubauer, Simon Veldhoen, Alexander Dierks, Reinhard Kaiser, Andreas Kunz, Meinrad Beer, Thorsten Bley
AIM: To evaluate the risk profile of sulfur hexafluoride in voiding urosonography (VUS) based on a large cohort of children. METHODS: Since 2011 sulfur hexafluoride (SH, SonoVue(®), Bracco, Italy) is the only ultrasound contrast available in the European Union and its use in children has not been approved. Within a 4-year-period, 531 children with suspected or proven vesicoureteral reflux (f/m = 478/53; mean age 4.9 years; 1 mo-25.2 years) following parental informed consent underwent VUS with administration of 2...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28212400/surveys-of-public-knowledge-and-attitudes-with-regard-to-antibiotics-in-poland-did-the-european-antibiotic-awareness-day-campaigns-change-attitudes
#9
Beata Mazińska, Izabela Strużycka, Waleria Hryniewicz
BACKGROUND: Antimicrobial resistance is a global public health problem. Monitoring the level of knowledge regarding antibiotics is a part of the European Union Community strategy against antimicrobial resistance. OBJECTIVE: To assess knowledge by the general public in Poland regarding antibiotics, AMR, and the impact of the European Antibiotic Awareness Day campaigns. METHODS: The repeated cross-sectional study was developed and carried out among the general public in Poland (in 5 waves between 2009 and 2011, embracing a total of 5004 respondents)...
2017: PloS One
https://www.readbyqxmd.com/read/28205429/-pneumococcal-arthritis-in-paediatric-population
#10
G Barbeito-Castiñeiras, M Guinda-Giménez, O Cores-Calvo, M Hernández-Blanco, F Pardo-Sánchez
OBJECTIVE: Cases of septic arthritis in paediatric population by Streptococcus pneumoniae in the Health Area of Santiago de Compostela (Spain) were reviewed. METHODS: A retrospective study from January 2005 to March 2014 was conducted for all S. pneumoniae isolates obtained from joint fluids in children. RESULTS: From the 7,416 joint fluids received in the Microbiology Department, 77 belonged to paediatric patients, and of these, only 8 had positive culture...
February 16, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28186843/risks-and-cough-aggravating-factors-in-prolonged-cough-epidemiological-observations-from-the-nagahama-cohort-study
#11
Hisako Matsumoto, Yumi Izuhara, Akio Niimi, Yasuharu Tabara, Tadao Nagasaki, Yoshihiro Kanemitsu, Kimihiko Murase, Tsuyoshi Oguma, Isao Ito, Shigeo Muro, Akihiro Sekine, Fumihiko Matsuda, Shinji Kosugi, Takeo Nakayama, Kazuo Chin, Michiaki Mishima
RATIONALE: Chronic cough hypersensitivity, a potentially important concept of chronic or prolonged cough, is featured by heightened cough response to low-intensity stimuli, which may be generated in the absence of airflow limitations or allergic conditions. However, there is little epidemiological evidence to support this. OBJECTIVES: In this large-scale community survey, we aimed to determine risks and cough-aggravating factors of prolonged cough, while focusing on serum IgE levels...
February 10, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28177594/investigation-of-chemosensitivity-during-and-after-an-acute-cold
#12
Robert Pellegrino, Ute Walliczek-Dworschak, Gudrun Winter, David Hull, Thomas Hummel
BACKGROUND: Viral rhinitis (the "common" cold) is a frequent worldwide disease. Olfactory dysfunction is one complication that arises during infection, which in most cases heals up spontaneously upon recovery, whereas in some cases it may persist as a partial or total loss of olfaction. The aim of this prospective study was to investigate the change of other chemosensory systems during a cold. METHODS: Fifty-eight patients (age 18 to 69 years) with an acute cold were compared to a healthy control group (n = 59; age 19 to 63 years)...
February 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28169979/acute-focal-dystonia-after-a-single-dose-of-oral-cetirizine-in-a-9-year-old-boy
#13
Indar Kumar Sharawat, Lesa Dawman
Common cold is an acute illness affecting pediatric population in particular. The use of antihistamines is a common practice, with cetirizine being a frequently used drug with a good safety profile. However, adverse events due to the use of antihistamines have been rarely reported, such as drug-induced dystonia with the use of cetirizine. In our present case, dystonia due to the intake of cetirizine was observed, which the patient responded well to the use of benzodiazapines, namely, clonazepam. We report this case to highlight the occurrence of this adverse event with the use of cetirizine...
February 4, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28163851/a-systematic-review-of-the-relationship-between-dystemprament-sue-mizaj-and-treatments-and-management-of-diseases-ilaj-and-eslah-e-mizaj
#14
REVIEW
Sepide Miraj, Samira Alesaeidi, Sara Kiani
BACKGROUND: Temperament refers to four different humors differentiating in individuals and, as a result, proposes specific therapy for diseases as well as special types of management (avoidance). OBJECTIVE: The aim of this study was to overview the relationship between dystemprament and treatment and management of diseases. METHODS: A computerized search of published articles was performed using PubMed, Scopus, Web of Science, and Medline databases as well as local sources from 1965 to 2016...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28161280/allergy-genuflection-it-s-surmount-with-special-focus-on-ear-nose-and-throat
#15
REVIEW
D Gupta, L Deshmukh, R Gupta, S S Sandhu
The system that protects body from infectious agents is immune system. On occasions, the system seldom reacts with some foreign particles and causes allergy. Allergies of the ear, nose and throat (ENT) often have serious consequences, including impairment and emotional strain that lowers the quality of life of patients. This is further responsible for the common cold, cough, tonsillitis, dermal infection, chest pain and asthma-like conditions which disturb one's day to day life. The present review enlightens some common ENT allergies which one can suffer more frequently in one's lifetime, and ignorance leads to making the condition chronic...
February 1, 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28154328/efficient-preparation-of-ephedrine-alkaloids-free-ephedra-herb-extract-and-its-antitumor-effect-and-putative-marker-compound
#16
Naohiro Oshima
 Ephedra Herb is a crude drug for the treatment of headache, bronchial asthma, nasal inflammation, and the common cold. Although it has been considered that ephedrine alkaloids (EAs) are the principal active ingredients of Ephedra Herb, EAs are known to induce palpitations, hypertension, insomnia, and dysuria as major side effects. Therefore, the administration of EAs-containing drugs to patients with cardiovascular-related diseases is strongly contraindicated. Previously, we isolated herbacetin 7-O-neohesperidoside from Ephedra Herb...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28146681/task-engagement-and-attentional-resources
#17
Gerald Matthews, Joel S Warm, Andrew P Smith
OBJECTIVE: Two studies tested multivariate models of relationships between subjective task engagement and vigilance. The second study included a stress factor (cold infection). Modeling tested relationships between latent factors for task engagement and vigilance, and the role of engagement in mediating effects of cold infection. BACKGROUND: Raja Parasuraman's research on vigilance identified several key issues, including the roles of task factors, arousal processes, and individual differences, within the framework of resource theory...
February 2017: Human Factors
https://www.readbyqxmd.com/read/28144200/efficacy-and-safety-of-oral-spray-containing-lysozyme-and-cetylpyridinium-subjective-determination-of-patients-with-tonsillopharyngitis
#18
Tarik Catic, Meliha Mehic, Zahida Binakaj, Bilsena Sahman, Vedina Cordalija, Amra Kerla, Igor Martinovic, Hajra Eskic
INTRODUCTION: Tonsillopharyngitis (sore throat) is a common disease mainly related to the seasonal common cold. To relieve unpleasant symptoms and discomfort of acute tonsillopharyngitis associated with common cold, patients usually take some non-prescription drugs. THE AIM: The primary aim of this study was to assess subjective determinations of the efficacy and the safety/tolerability of an oral spray comprising a combination of lysozyme chloride and cetylpyridinium chloride in those patients...
December 2016: Materia Socio-medica
https://www.readbyqxmd.com/read/28143507/prevalence-and-associated-factors-of-herbal-medicine-use-among-pregnant-women-on-antenatal-care-follow-up-at-university-of-gondar-referral-and-teaching-hospital-ethiopia-a-cross-sectional-study
#19
Abebe Basazn Mekuria, Daniel Asfaw Erku, Begashaw Melaku Gebresillassie, Eshetie Melese Birru, Balem Tizazu, Alima Ahmedin
BACKGROUND: Improving maternal and child health is one of the public health priorities in several African countries including Ethiopia. However, research on herbal medicine use during pregnancy is scarce in Ethiopia. The present study aimed at assessing the prevalence and correlates of herbal medicine use among pregnant women on antenatal care (ANC) follow-up at Gondar university referral hospital, Ethiopia METHODS: An institutional-based cross sectional study was conducted on 364 pregnant women attending ANC clinic from March to May 2016 at University of Gondar referral and teaching hospital, northwest Ethiopia...
February 1, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28137527/use-of-herbal-product-among-pregnant-women-in-turkey
#20
Aygül Kıssal, Ümran Çevik Güner, Döndü Batkın Ertürk
OBJECTIVE: This study was conducted to determine the herbal product use of pregnants as there is not adequate information relating to the rate of herbal product use during pregnancy in Turkey and what is thought about effects and side effects thereof. METHODS: It is a descriptive study consisted of 366 pregnants admitted to hospital for childbirth in gynaecology and obstetrics clinics of a public hospital or a university hospital. Data were collected with individual information form and question form of herbal product use in pregnancy...
February 2017: Complementary Therapies in Medicine
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