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Streptococcal pharyngitis

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https://www.readbyqxmd.com/read/29735420/-post-streptococcal-glomerulonephritis-in-the-south-of-tunisia-a-12-year-retrospective-review
#1
Bayen Maalej, Mona Ben Amor, Manel Jallouli, Manel Weli, Mohamed Charfi, Yassine Abdelkefi, Olfa Chakroun, Khaoula Kamoun, Jamil Hachicha, Noureddine Rekik, Taher Gargah, Lamia Gargouri, Abdelmajid Mahfoudh
AIM: Post-streptococcal glomerulonephritis (PSGN) is a frequent cause of acute nephritis in children. This study aimed to describe the epidemiology, clinical characteristics and outcomes of PSGN and look for predictor's factors of severity. METHODS: A 12-year retrospective review of case notes and laboratory data was conducted at a department of pediatrics, pediatric emergency and intensive care, Hedi Chaker Hospital. RESULTS: One hundred seventy eight children were treated for PSGN with a mean age of 7...
May 4, 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29731388/clinical-impact-of-a-rapid-streptococcal-antigen-test-on-antibiotic-use-in-adult-patients
#2
Monique Dodd, Allen Adolphe, Alisha Parada, Meghan Brett, Karissa Culbreath, Renée-Claude Mercier
INTRODUCTION: Adult pharyngitis is rarely attributable to group A streptococci. Utilization of a rapid streptococcal antigen test (RADT) may improve appropriate prescribing for bacterial pharyngitis. METHODS: Clinic 1 performed RADTs with subsequent Group A DNA probe test (GADNA) from November 2014-March 2015 and November 2015-March 2016 while Clinic 2 was the control clinic, then implemented the RADT with a GADNA from November 2015-March 2016. All GADNA results were obtained for each clinic from October 2013-March 2016...
April 7, 2018: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/29718302/caution-needed-molecular-diagnosis-of-pediatric-group-a-streptococcal-pharyngitis
#3
Robert R Tanz, Xiaotian T Zheng, Donna M Carter, Molly C Steele, Stanford T Shulman
Among throat swabs processed in the microbiology laboratory as back-up for negative rapid antigen detection test results, we found a significant increase in the proportion that tested positive for group A streptococci after changing from throat culture to a molecular test.For group A streptococcus testing, our hospital laboratory replaced throat cultures with a stand-alone molecular diagnostic test that takes no more than 1 hour to perform. The prevalence of positive laboratory test results increased significantly (P < ...
April 27, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29718291/molecular-testing-for-group-a-streptococcal-pharyngitis-to-test-or-not-to-test-that-is-the-question
#4
Preeti Jaggi, Amy Leber
No abstract text is available yet for this article.
April 27, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29704396/protective-immunity-induced-by-an-intranasal-multivalent-vaccine-comprising-10-lactococcus-lactis-strains-expressing-highly-prevalent-m-protein-antigens-derived-from-group-a-streptococcus
#5
Aniela Wozniak, Natalia Scioscia, Patricia C García, James B Dale, Braulio A Paillavil, Paulette Legarraga, Francisco J Salazar-Echegarai, Susan M Bueno, Alexis M Kalergis
Streptococcus pyogenes (group A Streptococcus) causes diseases ranging from mild pharyngitis to severe invasive infections. The N-terminal fragment of Streptococcal M protein elicits protective antibodies and is an attractive vaccine target. However, this N- terminal fragment is hypervariable and there are more than 200 different M types. We are developing an intranasal live bacterial vaccine comprised of 10 strains of Lactococcus lactis, each expressing one N-terminal fagment of M protein. Live bacterial-vectored vaccines have lower associated costs because of its less complex manufacturing processes compared to protein subunit vaccines...
April 28, 2018: Microbiology and Immunology
https://www.readbyqxmd.com/read/29691199/exploring-pharmacists-perceptions-regarding-influenza-and-streptococcal-testing-within-a-chain-pharmacy
#6
Kelli Dulaney, Kenneth Hohmeier, Cindy Fisher, Lindsey Cardosi, Mike Wasson
OBJECTIVES: To assess pharmacists' perceptions of point-of-care testing (POCT) and treatment for influenza and streptococcus pharyngitis in a community pharmacy setting. A secondary objective was to explore the correlation between demographic data and survey responses. METHODS: An anonymous electronic Likert-type-scale questionnaire was sent to pharmacists in a division of a large national supermarket chain pharmacy in western Tennessee, Mississippi, and Arkansas...
April 21, 2018: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29671499/poststreptococcal-illness-recognition-and-management
#7
David L Maness, Michael Martin, Gregg Mitchell
Group A beta-hemolytic streptococcus can cause several postinfectious, nonsuppurative immune- mediated diseases including acute rheumatic fever, poststreptococcal reactive arthritis, pediatric autoimmune neuropsychiatric disorders, and poststreptococcal glomerulonephritis. Except for sporadic outbreaks, poststreptococcal autoimmune syndromes occur most commonly in sub-Saharan Africa, India, Australia, and New Zealand. Children younger than three years are rarely affected by group A streptococcus pharyngitis or rheumatic fever, and usually do not require testing...
April 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29616606/streptococcal-group-a-c-and-g-pharyngitis-in-school-children-a-prospective-cohort-study-in-southern-india
#8
J John Melbin Jose, Kootallur N Brahmadathan, Vinod J Abraham, Chiung-Yu Huang, David Morens, Nancy P Hoe, Dean A Follmann, Richard M Krause
Diagnosing streptococcal pharyngitis in children on the basis of clinical appearance and throat culture is complicated by high colonisation rates and by the ability of other pathogens to cause clinically similar disease. To characterise the epidemiology of Lancefield Group A, C and G β-haemolytic streptococcus (GAS, GCS and GGS, respectively) in children, we conducted a 2-year prospective study of 307 school children between 7 and 11 years old. GGS and GAS were commonly identified organisms both for silent streptococcal colonisation and symptomatic sore throat, while GCS was uncommonly found...
April 4, 2018: Epidemiology and Infection
https://www.readbyqxmd.com/read/29533349/a-clear-cut-case-of-acute-rheumatic-fever-after-group-g-streptococcal-pharyngitis-in-new-zealand
#9
Diana Lennon
No abstract text is available yet for this article.
April 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29530660/streptococcal-pharyngitis-and-rheumatic-heart-disease-the-superantigen-hypothesis-revisited
#10
REVIEW
Jacklyn R Hurst, Katherine J Kasper, Akshay N Sule, John K McCormick
Streptococcus pyogenes is a human-specific and globally prominent bacterial pathogen that despite causing numerous human infections, this bacterium is normally found in an asymptomatic carrier state. This review provides an overview of both bacterial and human factors that likely play an important role in nasopharyngeal colonization and pharyngitis, as well as the development of acute rheumatic fever and rheumatic heart disease. Here we highlight a recently described role for bacterial superantigens in promoting acute nasopharyngeal infection, and discuss how these immune system activating toxins could be crucial to initiate the autoimmune process in rheumatic heart disease...
July 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29523424/clinical-mimics-an-emergency-medicine-focused-review-of-streptococcal-pharyngitis-mimics
#11
Michael Gottlieb, Brit Long, Alex Koyfman
BACKGROUND: Pharyngitis is a common disease in the emergency department (ED). Despite a relatively low incidence of complications, there are many dangerous conditions that can mimic this disease and are essential for the emergency physician to consider. OBJECTIVE: This article provides a review of the evaluation and management of group A β-hemolytic Streptococcal (GABHS) pharyngitis, as well as important medical conditions that can mimic this disease. DISCUSSION: GABHS pharyngitis often presents with fever, sore throat, tonsillar exudates, and anterior cervical lymphadenopathy...
May 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29517940/clinical-features-predicting-group-a-streptococcal-pharyngitis-in-a-japanese-paediatric-primary-emergency-medical-centre
#12
Masahiro Nishiyama, Ichiro Morioka, Mariko Taniguchi-Ikeda, Takeshi Mori, Kazumi Tomioka, Keita Nakanishi, Junya Fujimura, Noriyuki Nishimura, Kandai Nozu, Hiroaki Nagase, Kazuto Ishibashi, Akihito Ishida, Kazumoto Iijima
Objectives To identify clinical features that predict Group A streptococcal (GAS) pharyngitis in a Japanese paediatric primary emergency medical centre. Methods The prevalence of GAS pharyngitis according to age and body temperature (BT) was calculated among 3098 paediatric patients with pharyngitis. The numbers of GAS-positive and -negative patients for each clinical parameter, and each point increase in the McIsaac score were compared and likelihood ratios (LRs) were calculated. Results The prevalence of GAS pharyngitis was extremely low in patients aged < 1 (1...
May 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29491014/foodborne-outbreak-of-group-g-streptococcal-pharyngitis-in-a-school-dormitory-in-osaka-japan
#13
Takahiro Yamaguchi, Ryuji Kawahara, Chihiro Katsukawa, Masashi Kanki, Tetsuya Harada, Shinya Yonogi, Satomi Iwasaki, Hirokazu Uehara, Saori Okajima, Hiroshi Nishimura, Kazushi Motomura, Masaya Miyazono, Yuko Kumeda, Kentaro Kawatsu
In September 2016, 140 patients with primary symptoms of sore throat and fever were identified in a school dormitory in Osaka, Japan. Epidemiological and laboratory investigations determined that these symptomatic conditions were from a foodborne outbreak of group G streptococcus (GGS), with GGS being isolated from samples from patients, cooks, and foods. The strain of GGS was identified as Streptococcus dysgalactiae subsp. equisimilis of two emm types ( stG652.0 and stC36.0 ). The causative food, a broccoli salad, was contaminated with the two types of S...
May 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29452197/essential-oils-from-origanum-vulgare-and-salvia-officinalis-exhibit-antibacterial-and-anti-biofilm-activities-against-streptococcus-pyogenes
#14
Niluni M Wijesundara, H P Vasantha Rupasinghe
In the present study, essential oils (EOs) extracted from oregano, sage, cloves, and ginger were evaluated for the phytochemical profile, antibacterial, and anti-biofilm activities against Streptococcus pyogenes. The broth microdilution method was used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of EOs. The minimum biofilm inhibitory concentrations (MBICs) were determined using MTT assay and fixed biofilms were observed through scan electron microscopy...
April 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29426305/adherence-to-guidelines-for-testing-and-treatment-of-children-with-pharyngitis-a-retrospective-study
#15
Thea Brennan-Krohn, Al Ozonoff, Thomas J Sandora
BACKGROUND: Group A streptococcus (GAS) is the most common bacterial etiology of pharyngitis but is difficult to distinguish clinically from viral pharyngitis. There are benefits to early antibacterial treatment of GAS pharyngitis, but administering antibiotics to children with viral pharyngitis is ineffective and costly. We evaluated adherence to guidelines that were developed to help clinicians distinguish between viral and GAS pharyngitis and guide management. METHODS: Retrospective cohort study of patients ages 3-18 who had a rapid streptococcal test and/or throat culture performed in an outpatient setting...
February 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29401105/deep-vein-thrombosis-in-a-young-healthy-baseball-catcher-a-case-report-and-review-of-the-literature
#16
Kimberly K Abood, Megan Rose Paul, Dennis John Kuo
Venous thromboembolism is becoming increasingly recognized as a significant cause of morbidity and mortality in the hospitalized pediatric population. However, young healthy athletes can present with unique risk factors for deep vein thrombosis (DVT) that can be overlooked. Here we report a case of an adolescent male with no inherited risk factors or prior history of DVTs who developed a right femoral vein DVT in the context of playing catcher in baseball after recovering from a bout of streptococcal pharyngitis...
February 2, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29359701/deletion-of-from-streptococcus-pyogenes-results-in-hypervirulence-in-a-mouse-model-of-sepsis-and-is-luxs-independent
#17
Izabela Sitkiewicz, James M Musser
Group A Streptococcus (GAS) is a Gram-positive human pathogen that causes a variety of diseases ranging from pharyngitis to life-threatening streptococcal toxic shock syndrome. Recently, several global gene expression analyses have yielded extensive new information regarding the regulation of genes encoding known and putative virulence factors in GAS. A microarray analysis found that transcription of the GAS gene M5005_Spy_1343 was significantly increased in response to interaction with human polymorphonuclear leukocytes...
March 30, 2017: Polish Journal of Microbiology
https://www.readbyqxmd.com/read/29351278/analysis-of-the-tonsillar-microbiome-in-young-adults-with-sore-throat-reveals-a-high-relative-abundance-of-fusobacterium-necrophorum-with-low-diversity
#18
T Prescott Atkinson, Robert M Centor, Li Xiao, Fuchenchu Wang, Xiangqin Cui, William Van Der Pol, Casey D Morrow, Amy E Ratliff, Donna M Crabb, Arthur H Totten, Carlos A Estrada, Michael B Faircloth, Ken B Waites
Fusobacterium necrophorum (Fn), a gram-negative anaerobe, is increasingly implicated as an etiologic agent in older adolescents and young adults with sore throat. Inadequately treated Fn pharyngitis may result in suppurative complications such as peritonsillar abscess and Lemierre's syndrome. Data from the literature suggest that the incidence of life-threating complications in these age groups from Fn pharyngitis (Lemierre's syndrome) in the United States exceeds those associated with group A beta-hemolytic streptococcal (GAS) pharyngitis (acute rheumatic fever)...
2018: PloS One
https://www.readbyqxmd.com/read/29322750/use-of-streptococcus-salivarius-k12-to-reduce-the-incidence-pharyngo-tonsillitis-and-acute-otitis-media-in-children-a-retrospective-analysis-in-not-recurrent-pediatric-subjects
#19
Francesco DI Pierro, Paolo Risso, Elena Poggi, Anna Timitilli, Sara Bolloli, Maurizio Bruno, Egidio Caneva, Riccardo Campus, Alessandro Giannattasio
BACKGROUND: Previous trials, performed in subjects affected by recurrent streptococcal pharyngo-tonsillar infection, have shown that the use for 90 days of Streptococcus salivarius K12 (K12), an oral colonizing probiotic producing lantibiotic bacteriocins, reduces the occurrence of streptococcal and viral pharyngitis and acute otitis media (AOM). The aim was to evaluate the role of K12 in reducing the incidence of streptococcal and viral pharyngo-tonsillitis and AOM when administered in two separate trimesters, from October to December and then from April to June, in pediatric subjects with non-recurrent streptococcal infection...
January 11, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/29319521/polish-physicians-attitudes-towards-antibiotic-prescription-and-antimicrobial-resistance
#20
Beata Mazińska, Waleria Hryniewicz
Antimicrobial resistance has been one of the biggest global current issues in medicine and public health. Overuse and imprudent use of antimicrobial agents are recognized as one of the leading causes of antibiotic resistance. The aim of this study was to analyze the attitudes of Polish physicians practicing at the community level towards antibiotics and antimicrobial resistance. The majority of physicians taking part in the survey believed that Polish people overuse antibiotics (98%). Most physicians (91%) considered that antimicrobial resistance is a major problem at present...
September 27, 2017: Polish Journal of Microbiology
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