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https://www.readbyqxmd.com/read/27727258/-let-us-not-forget-the-lemierre-s-syndrome
#1
Stefano Cappanera, Beatrice Tiri, Lavinia M Saraca, Daniela Francisci
Lemierre's syndrome is a dangerous potential sequela of pharyngitis that results in septic thrombophlebitis of the internal jugular vein. A high index of suspicion is needed to consider this diagnosis in the workup of pharyngitis and should be aggressively treated once. Gram-negative anaerobic bacteria, mainly Fusobacterium necrophorum are implicated. Before the antibiotic era, Lemierre's syndrome was common and often fatal. But with the introduction of penicillin in the 1940s, the incidence of the syndrome dropped, and it eventually became known as the "forgotten disease"...
September 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27386622/-sepsis-due-to-fusobacteria-in-a-young-adult
#2
Gerhard Kernbach-Wighton, Rainer Amberg, Marijo Parchina, Cornelius Hess, Burkhard Madea
Fusobacteria belong to the normal population of the pharyngeal mucosa as well as the mucosa of the upper airways and the gastrointestinal tract. Infections are comparatively rare. The most common causative organism is Fusobacterium necrophorum. A well-known infection caused by this germ is Lemierre's syndrome. In the presented case, a 19-year-old man (123 kg body weight, 186 cm body length) was found dead in his bed in the morning after having complained of muscular fatigue and vomiting the previous day. Autopsy was carried out only two days after death...
May 2016: Archiv Für Kriminologie
https://www.readbyqxmd.com/read/26638515/-loco-regional-complications-of-pharyngitis-the-example-of-lemierre-s-syndrome
#3
J Tschopp, C Chuard
Pharyngitis is a common cause of consultation in ambulatory medicine. Although it is benign in most cases, serious complications may happen and must be recognized quickly. Lemierre's syndrome is one of them. It consists in the association of thrombosis of the internal jugular vein and septic emboli that generally involve the lungs and is classically associated with Fusobacterium necrophorum. It is usually found in young and healthy adults and has an estimated mortality of 5%. Diagnosis relies essentially on the characteristic presentation of the disease...
October 7, 2015: Revue Médicale Suisse
https://www.readbyqxmd.com/read/26368857/lemierre-disease-a-case-with-multilevel-epidural-abscess-and-aggressive-neurological-weakness-case-report-and-literature-review
#4
Philip M Sinatra, Dirk H Alander
BACKGROUND: Lemierre disease is a rare postanginal sepsis caused by the anaerobe Fusobacterium necrophorum. It is associated with a pharyngitis that progresses quickly to thrombophlebitis of the internal jugular vein and metastatic abscesses to pulmonary, soft tissue, articular, and organ systems. It is rarely associated with spinal epidural abscesses. Because of the increasing antibiotic resistance, its incidence is on the rise. METHODS: A single-patient case report of an adolescent male who initially presented to our institution for bacteremia and febrile episodes...
January 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/26266187/grave-complication-of-pharyngitis-lemierre-syndrome
#5
Suthar Pokhraj Prakashchandra, Ankit Kumar B Patel, Kimmyben Patel, Raj Kumar P Doshi, Narottam A Patel
Fusobacterium necrophorum is the causative agent in the pharyngitis. After invasion of the oropharyngeal mucosa by the organism leads to the development of the grave complications like superficial thrombophlebitis of internal jugular vein, septic emboli in the lung and coagulopathy. A 23-year-old male presented with chief complaints of sore throat, headache and high grade fever with past history of upper respiratory tract infection one month ago. On examination, he had high grade fever, tachycardia, hypotension and tender cervical lymph nodes...
June 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26236610/fusobacterium-necrophorum-presenting-as-isolated-lung-nodules
#6
Rajiv Sonti, Christine Fleury
Fusobacterium necrophorum causes Lemierre's syndrome - a dramatic and distinct condition beginning with pharyngitis before proceeding to internal jugular vein septic thrombophlebitis and respiratory tract infection in otherwise healthy individuals. It is rare, but by far the most common pathway to parenchymal lung disease with this organism. Here we describe we a 34 year old healthy lady who was nontoxic without any antecedent illness who presented with lung nodules due to fusobacterium necrophorum as the sole manifestation of disease...
2015: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/26163394/-pleuro-pneumonia-revealing-septic-thrombophlebitis-of-the-jugular-vein-think-about-the-lemierre-s-syndrome
#7
P Habert, R Tazi-Mezalek, J Guinde, S Martinez, S Laroumagne, P Astoul, H Dutau
INTRODUCTION: Infection by Fusobacterium necrophorum, a Gram negative anaerobic bacteria, can lead to the development of Lemierre's syndrome, an uncommon but potentially fatal infection of the internal jugular vein. Since the introduction of antibiotics, the morbidity and mortality associated with this syndrome have been dramatically reduced. This syndrome is characterized by a pharyngeal infection, which leads to the development of septic thrombophlebitis of the internal jugular vein with septic emboli, which usually spread into the lung...
January 2016: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/26117393/importance-of-blood-cultures-to-aid-the-diagnosis-of-lemierre-s-syndrome
#8
Maryam Nejat, Anja Werno
This is a case report of Lemierre's syndrome, a septic thrombophlebitis of the internal jugular vein (IJV) usually preceded by pharyngitis and bacteraemia with an anaerobic organism. Fusobacterium necrophorum is ananaerobic Gram-negative bacillus and is the most common organism reported to cause Lemierre's syndrome which usually occurs one to three weeks post pharyngitis or oropharyngeal surgery. A 21-year-old patient presented with signs of sepsis and a history of sore throat, fever, and tender cervical lymph nodes...
May 15, 2015: New Zealand Medical Journal
https://www.readbyqxmd.com/read/26075768/fusobacterium-positive-and-streptococcal-positive-pharyngitis
#9
LETTER
Robert M Centor, T Prescott Atkinson, Ken B Waites
No abstract text is available yet for this article.
June 16, 2015: Annals of Internal Medicine
https://www.readbyqxmd.com/read/26075767/fusobacterium-positive-and-streptococcal-positive-pharyngitis
#10
LETTER
James R Uhl, Daniel R Gustafson, Stefanea L Rucinski, Robin Patel
No abstract text is available yet for this article.
June 16, 2015: Annals of Internal Medicine
https://www.readbyqxmd.com/read/26075766/fusobacterium-positive-and-streptococcal-positive-pharyngitis
#11
LETTER
Jan Matthys, Marc De Meyere, An De Sutter
No abstract text is available yet for this article.
June 16, 2015: Annals of Internal Medicine
https://www.readbyqxmd.com/read/26000185/uterine-necrosis-associated-with-fusobacterium-necrophorum-infection
#12
T Widelock, R Elkattah, S Gibbs, Z Mashak, S Mohling, S DePasquale
Fusobacterium necrophorum is infrequently implicated as a pathogenic organism. When pathogenic, the typical clinical presentation is that of pharyngitis, cervical adenopathy, and unilateral thrombophlebitis of the internal jugular vein. Infections caused by Fusobacterium necrophorum within the fields of obstetrics and gynecology have been infrequently reported. We describe a 19-year-old woman who underwent a cesarean delivery complicated by sepsis and purulent uterine necrosis secondary to Fusobacterium necrophorum infection...
2015: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/25889618/liver-abscessation-and-multiple-septic-pulmonary-emboli-associated-with-lemierre-s-syndrome-a-case-report
#13
Yuichi Takano, Kenichiro Fukuda, Hiromi Takayasu, Kazuki Shinmura, Go Koizumi, Masahiro Sasai, Yoshikuni Nagayama, Michiari Kawamo, Tomohiro Yasuda, Kazumasa Watanabe, Jun Sasaki, Munetaka Hayashi, Eiichi Yamamura, Naotaka Maruoka, Masatsugu Nagahama, Hiroshi Takahashi
BACKGROUND: In Lemierre's syndrome, patients first exhibit pharyngitis and peritonsillar abscessation, followed by the development of anaerobic bacterial (usually Fusobacterium necrophorum) septicemia and metastatic infections throughout the body. However, these infections rarely affect the liver. We describe a case of Lemierre's syndrome, in which the first disease manifestation was liver abscess, for drawing attention of emergency physicians to this rare but fatal disease. CASE PRESENTATION: A 28-year-old Asian ethnicity Filipino male, who was previously healthy, entered the emergency department presenting with fever and pharyngeal pain that had persisted for 5 days...
March 3, 2015: BMC Research Notes
https://www.readbyqxmd.com/read/25777231/liver-abscessation-and-multiple-septic-pulmonary-emboli-associated-with-lemierre-s-syndrome-a-case-report
#14
Yuichi Takano, Kenichiro Fukuda, Hiromi Takayasu, Kazuki Shinmura, Go Koizumi, Masahiro Sasai, Yoshikuni Nagayama, Michiari Kawamo, Tomohiro Yasuda, Kazumasa Watanabe, Jun Sasaki, Munetaka Hayashi, Eiichi Yamamura, Naotaka Maruoka, Masatsugu Nagahama, Hiroshi Takahashi
BACKGROUND: In Lemierre's syndrome, patients first exhibit pharyngitis and peritonsillar abscessation, followed by the development of anaerobic bacterial (usually Fusobacterium necrophorum) septicemia and metastatic infections throughout the body. However, these infections rarely affect the liver. We describe a case of Lemierre's syndrome, in which the first disease manifestation was liver abscess, for drawing attention of emergency physicians to this rare but fatal disease. CASE PRESENTATION: A 28-year-old Asian ethnicity Filipino male, who was previously healthy, entered the emergency department presenting with fever and pharyngeal pain that had persisted for 5 days...
December 2015: BMC Research Notes
https://www.readbyqxmd.com/read/25686164/the-clinical-presentation-of-fusobacterium-positive-and-streptococcal-positive-pharyngitis-in-a-university-health-clinic-a-cross-sectional-study
#15
Robert M Centor, T Prescott Atkinson, Amy E Ratliff, Li Xiao, Donna M Crabb, Carlos A Estrada, Michael B Faircloth, Lisa Oestreich, Jeremy Hatchett, Walid Khalife, Ken B Waites
BACKGROUND: Pharyngitis guidelines focus solely on group A β-hemolytic streptococcal infection. European data suggest that in patients aged 15 to 30 years, Fusobacterium necrophorum causes at least 10% of cases of pharyngitis; however, few U.S. data exist. OBJECTIVE: To estimate the prevalence of F. necrophorum; Mycoplasma pneumoniae; and group A and C/G β-hemolytic streptococcal pharyngitis and to determine whether F. necrophorum pharyngitis clinically resembles group A β-hemolytic streptococcal pharyngitis...
February 17, 2015: Annals of Internal Medicine
https://www.readbyqxmd.com/read/25560619/incomplete-lemierre-syndrome
#16
REVIEW
Joseph Shiber, Emily Fontane, Ronald Rabinowitz, David Gens, Nader Habashi, Thomas Scalea
An invasive Fusobacterium infection may originate from an apparent routine pharyngitis and lead to significant distant septic complications. Even without internal jugular thrombosis, the same mechanism of disease exists, and therefore, the same morbidity, prognosis, and treatments are applicable, hence the suitable term incomplete Lemierre syndrome. We present a case of invasive Fusobacterium infection that meets all criteria for Lemierre syndrome except lacking internal jugular thrombosis. A review of the literature that forms the diagnostic criteria for this syndrome and the rationale for our creating this novel term is presented...
January 2015: Pediatric Emergency Care
https://www.readbyqxmd.com/read/24585168/lemierre-syndrome-not-so-forgotten
#17
Nishant Gupta, Stephen M Kralovic, Dennis McGraw
Lemierre syndrome is a rare and life-threatening illness. Often referred to as "the forgotten disease," its incidence is reported to be as low as 1 in a million. The microorganism responsible for Lemierre syndrome is typically Fusobacterium necrophorum. The bacterium starts in the pharynx and peritonsillar tissue, then disseminates through lymphatic vessels. Severe sepsis rapidly develops, as does the hallmark of this syndrome: septic thrombophlebitis of the internal jugular vein. This report describes a case of Lemierre syndrome in a previously healthy 26-year-old man with life-threatening internal jugular vein thrombophlebitis following 2 weeks of an indolent course of pharyngitis...
March 2014: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/24326047/-imaging-of-lemierre-in-children-and-young-adults
#18
Lysiane Trachsel, Jacques Cherpillod, Leonor Alamo Maestre, François Gudinchet
PURPOSE: The aim of this study is to describe the role of imaging in the medical care of Lemierre Syndrome and to describe its US, CT and MRI features. PATIENTS AND METHODS: Files of patients diagnosed with Lemierre Syndrome between 2005 and 2011 at CHUV hospital have been analysed retrospectively to define its imaging semiology. RESULTS: IJV thrombosis was demonstrated by US, CT and MRI. Septic pulmonary emboli were detected by CT. Complications of the Lemierre Syndrome were depicted by MR and CT...
December 11, 2013: Praxis
https://www.readbyqxmd.com/read/23784917/lemierre-syndrome-study-of-11-cases-and-literature-review
#19
REVIEW
Christian Adrien Righini, Alexandre Karkas, Romain Tourniaire, Jean-Michel N'Gouan, Sébastien Schmerber, Emile Reyt, Ihab Atallah
BACKGROUND: Lemierre syndrome is a rare but serious illness that associates throat infection and thrombosis of the internal jugular vein (IJV) or one of its tributaries with subsequent distant septic emboli. The purpose of our study was to review the pathogenesis, clinical presentation, and treatment of this disease. METHODS: Patients with confirmed Lemierre syndrome were included in our retrospective monocentric study. All patients had bacteriologic analyses as well as radiologic imaging...
July 2014: Head & Neck
https://www.readbyqxmd.com/read/23761916/the-connection-between-ruptured-cerebral-aneurysms-and-odontogenic-bacteria
#20
Mikko J Pyysalo, Liisa M Pyysalo, Tanja Pessi, Pekka J Karhunen, Juha E Öhman
BACKGROUND: Patients with ruptured saccular intracranial aneurysms have excess long-term mortality due to cerebrovascular and cardiovascular diseases compared with general population. Chronic inflammation is detected in ruptured intracranial aneurysms, abdominal aortic aneurysms and coronary artery plaques. Bacterial infections have been suggested to have a role in the aetiology of atherosclerosis. Bacteria have been detected both in abdominal and coronary arteries but their presence in intracranial aneurysms has not yet been properly studied...
November 2013: Journal of Neurology, Neurosurgery, and Psychiatry
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