keyword
https://read.qxmd.com/read/38546503/efficacy-of-aspiration-assisted-ureteral-access-sheath-clearpetra-in-retrograde-intrarenal-surgery
#1
JOURNAL ARTICLE
Mustafa Erkoc, Muammer Bozkurt, Mehmet Ali Sezgin, Levent Ozcan, Osman Can, Eyyüp Danis, Emre Can Polat, Alper Otunctemur
Backgrounds: In the renal intrarenal stone surgery (RIRS) procedure, ureteral access sheath (UAS) is still used in the majority of surgeries to both protect the flexible ureteroscope (FURS) and reduce intrarenal pressure. ClearPETRA is a new UAS that has an integrated aspiration port. We aimed to evaluate the clinical outcomes and effectiveness of Aspiration-Assisted UAS (ClearPETRA) in the RIRS procedure. Methods: One thousand six hundred twenty patients who underwent RIRS between January 2021 and January 2024 were evaluated retrospectively and 512 patients were included in the study...
March 28, 2024: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://read.qxmd.com/read/38545762/daily-ecological-momentary-assessments-of-pain-and-ability-to-work-after-ureteroscopy-and-stenting
#2
JOURNAL ARTICLE
Russell E N Becker, John Michael Dibianco, Andrew Higgins, Jeremy Konheim, Eduardo Kleer, David A Leavitt, Andre King, Naveen Kachroo, Sami Majdalany, David Gandham, Golena Fernandez Moncaleano, Bronson Conrado, Elaina Shoemaker, Stephanie Daignault, Casey A Dauw, Khurshid R Ghani
Introduction Ureteral stents can cause significant patient discomfort, yet the temporal dynamics and impact on activities remain poorly characterized. We employed an automated tool to collect daily ecological momentary assessments (EMA) regarding pain and ability to work following ureteroscopy with stenting. Our aim was to assess feasability, and better characterize the postoperative patient experience. Methods As an exploratory endpoint within an ongoing clinical trial, patients undergoing ureteroscopy with stenting were asked to complete daily EMAs for 10 days postoperatively, or until the stent was removed...
March 28, 2024: Journal of Endourology
https://read.qxmd.com/read/38545755/percutaneous-nephrolithotomy-pcnl-for-de-novo-urolithiasis-after-kidney-transplantation-a-systematic-review-of-the-literature
#3
JOURNAL ARTICLE
Clara Cerrato, Victoria Jahrreiss, Carlotta Nedbal, Francesco Ripa, Vincenzo de Marco, Manoj Monga, Bm Zeeshan Hameed, Peter Kronenberg, Amelia Pietropaolo, Nithesh Naik, Bhaskar K Somani
INTRODUCTION AND OBJECTIVE: Renal transplantation is the treatment for end stage renal disease that offers better quality of life and survival. Among the possible complications that might affect allografts, urolithiasis might have severe consequences, causing acute kidney injury(AKI) or septic events in immunocompromised patients. Allograft stones might be treated with percutaneous nephrolithotomy(PCNL). The aim of this Cochrane style review was to assess the safety and efficacy of PCNL in patients with renal transplant...
March 28, 2024: Journal of Endourology
https://read.qxmd.com/read/38544324/prevalence-and-characteristics-of-genetic-disease-in-adult-kidney-stone-formers
#4
JOURNAL ARTICLE
Manuel A Anderegg, Eric G Olinger, Matteo Bargagli, Rob Geraghty, Lea Taylor, Alexander Nater, Rémy Bruggmann, John A Sayer, Bruno Vogt, André Schaller, Daniel G Fuster
BACKGROUND: Molecular mechanisms of kidney stone formation remain unknown in most patients. Previous studies showed high a heritability of nephrolithiasis, but data on prevalence and characteristics of genetic disease in unselected adults with nephrolithiasis are lacking. This study was conducted to fill this important knowledge gap. METHODS: We performed whole exome sequencing in 787 participants of the Bern Kidney Stone Registry, an unselected cohort of adults with ≥ 1 past kidney stone episode (KSF), and 114 non-stone-forming individuals (NKSF)...
March 27, 2024: Nephrology, Dialysis, Transplantation
https://read.qxmd.com/read/38534089/learning-curve-of-ultrasound-guided-percutaneous-nephrolithotripsy-in-the-treatment-of-complex-renal-calculi
#5
JOURNAL ARTICLE
Zhaoxiang Lu, Wentie Yang, Wei He
OBJECTIVE: This study was performed to investigate the learning curve of ultrasound-guided percutaneous nephrolithotripsy (PCNL) for the treatment of complex renal calculi. METHODS: Seventy-two patients with complex renal stones who underwent ultrasound-guided PCNL by the same operator from November 2016 to September 2020 were retrospectively analyzed. The learning curve of PCNL for complex renal stones was analyzed using multifactorial cumulative sum (CUSUM) analysis and best-fit curves...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38533318/causality-between-allergic-diseases-and-kidney-diseases-a-two-sample-mendelian-randomization-study
#6
JOURNAL ARTICLE
Zhe Peng, Xinyu Dong, Yingxin Long, Zunjiang Li, Yueyao Wang, Wei Zhu, Banghan Ding
BACKGROUND: Evidence from observational studies and clinical trials suggests that the allergic diseases (ADs) are associated with kidney diseases (KDs). However, the causal association between them remains to be determined. We used bidirectional two-sample Mendelian randomization (MR) analysis to evaluate the potential causality between them. METHODS: Mendelian randomization (MR) was performed using publicly available genome-wide association study (GWAS) summary datasets...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38533276/primary-hyperparathyroidism-in-young-and-adolescents-alike-or-unlike-adult-hyperparathyroidism-a-series-from-south-india
#7
JOURNAL ARTICLE
Dhalapathy Sadacharan, Smitha S Rao, Shriraam Mahadevan, G Shanmugasundar, S Murthy, Shruti Chandrashekaran, Vijay Bhaskar Reddy, Bharath Ramji
BACKGROUND: Primary hyperparathyroidism (PHPT) is a common endocrine condition but rare in the pediatric and adolescent populations. The presentations can be unique, accounting for significant morbidity in the case of untimely detection. AIM: To study surgically treated pediatric PHPT retrospectively. METHODS: Surgically treated children of PHPT up to 20 years of age between 2010 to 2022 were analyzed. All of them were operated on by an endocrine surgeon and team...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38532342/treatment-of-ureteropelvic-junction-obstruction-in-patients-with-renal-calculi-via-laparoscopic-pyeloplasty-and-flexible-vacuum-assisted-ureteral-access-sheath-ureteroscopy-a-multicenter-retrospective-observational-study
#8
JOURNAL ARTICLE
Yang Mi, Zhiqin Kang, Jingyu Wang, Liang Yan, Jun Zhang
BACKGROUND: Ureteropelvic junction obstruction (UPJO) is a common obstructive disease of the urinary tract. UPJO patients commonly exhibit coexistent renal calculi. The main aim of therapy is to relieve the obstruction and remove the stones at the same time. METHODS: This retrospective study included 110 patients diagnosed with UPJO coexisting with multiple renal calculi at Shanxi Bethune Hospital and the First Hospital of Shanxi Medical University between March 2016 and January 2022...
March 26, 2024: BMC Urology
https://read.qxmd.com/read/38530430/quantitative-susceptibility-mapping-for-detection-of-kidney-stones-hemorrhage-differentiation-and-cyst-classification-in-adpkd
#9
JOURNAL ARTICLE
Karl Schumacher, Martin R Prince, Jon D Blumenfeld, Hanna Rennert, Zhongxiu Hu, Hreedi Dev, Yi Wang, Alexey V Dimov
BACKGROUND AND PURPOSE: The objective is to demonstrate feasibility of quantitative susceptibility mapping (QSM) in autosomal dominant polycystic kidney disease (ADPKD) patients and to compare imaging findings with traditional T1/T2w magnetic resonance imaging (MRI). METHODS: Thirty-three consecutive patients (11 male, 22 female) diagnosed with ADPKD were initially selected. QSM images were reconstructed from the multiecho gradient echo data and compared to co-registered T2w, T1w, and CT images...
March 26, 2024: Abdominal Radiology
https://read.qxmd.com/read/38529424/comparison-of-stone-score-guy-s-stone-score-croes-nomogram-and-seoul-national-university-renal-stone-complexity-score-in-prognosticating-outcomes-of-multiple-tract-mini-percutaneous-nephrolithotomy-a-retrospective-study
#10
JOURNAL ARTICLE
Khalid Farooq, Najma Hameed, Zainab Zaib, Muhammad Bilal Hameed, Husnain Ausaf, Fraz Shakil, Muhammad Afzaal Nawaz
Objective  The objective of this study was to compare the STONE score (Size of the stone, Topography or location, degree of Obstruction of the urinary system, Number of stones, and Evaluation of Hounsfield units), Guy's stone score (GSS), Clinical Research Office of the Endourological Society (CROES) nomogram, and Seoul National University Renal Stone Complexity Score (RSCS) in prognosticating multiple tract mini-percutaneous nephrolithotomy (mPCNL) outcome. Methodology This descriptive retrospective analysis was carried out at the Urology Department, Lady Reading Hospital, Peshawar, Pakistan...
February 2024: Curēus
https://read.qxmd.com/read/38528055/decreased-calcium-permeability-caused-by-biallelic-trpv5-mutation-leads-to-autosomal-recessive-renal-calcium-wasting-hypercalciuria
#11
JOURNAL ARTICLE
Naz Guleray Lafci, Mark van Goor, Semra Cetinkaya, Jenny van der Wijst, Melisa Acun, Fatma Kurt Colak, Arda Cetinkaya, Joost Hoenderop
Hypercalciuria is the most common metabolic risk factor in people with kidney stone disease. Its etiology is mostly multifactorial, although monogenetic causes of hypercalciuria have also been described. Despite the increased availability of genetic diagnostic tests, the vast majority of individuals with familial hypercalciuria remain unsolved. In this study, we investigated a consanguineous pedigree with idiopathic hypercalciuria. The proband additionally exhibited severe skeletal deformities and hyperparathyroidism...
March 25, 2024: European Journal of Human Genetics: EJHG
https://read.qxmd.com/read/38526140/kidney-stones-account-for-increased-imaging-studies-in-autosomal-dominant-polycystic-kidney-disease
#12
JOURNAL ARTICLE
Kathryn E Simmons, Lawrence S Ullman, Neera K Dahl
INTRODUCTION: ADPKD patients may have more imaging studies than patients with other forms of chronic kidney disease (CKD). We characterized the imaging burden of ADPKD patients relative to a CKD population to determine which factors lead to increased imaging in ADPKD patients. METHODS: We retrospectively reviewed patients seen at Yale Nephrology between January 2012 and January 2021. We collected demographic, clinical, and imaging data through automated query and manual chart review...
March 25, 2024: Kidney360
https://read.qxmd.com/read/38524503/perioperative-and-long-term-results-of-ultrasonography-guided-single-and-multiple-tract-percutaneous-nephrolithotomy-for-staghorn-calculi
#13
JOURNAL ARTICLE
Rui-Xiang Cheng, Ni Dai, Yan-Min Wang, Pei Qi, Fen Chen
BACKGROUND: It is possible that this condition will lead to urosepsis and progressive deterioration of renal function in the absence of surgical intervention. Several recent clinical studies have shown that multi-tract percutaneous nephrolithotomy (M-PCNL) has a similar stone free rate (SFR) as standard percutaneous nephrolithotomy (S-PCNL). As a result, M-PCNL was also recommended as a treatment option for staghorn calculi. AIM: To examine the perioperative and long-term results of ultrasonography-guided single- and M-PCNL...
March 6, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38523999/filling-in-the-gaps-ethylene-glycol-poisoning-presenting-with-isolated-lactate-and-osmolar-gaps
#14
Caden Quintanilla, Justin Panthappattu, Davood Hosseini, Karan Omidvari
Ethylene glycol (EG) is an organic compound used in antifreeze. In 2020 alone, there were 5,277 EG exposures, with only 617 reported as intentional ingestions. Therefore, encountering EG toxicity is rare; however, it is essential to identify it promptly based on a focused history, exam, and rapid identification of commonly associated EG-induced metabolic derangements. If the diagnosis is not made within 12 hours of ingestion or exposure, severe morbidity and mortality can occur. Previous reports of EG poisoning have occurred in the setting of a lactate gap (LG) and osmolar gap (OG); however, they also had commonly associated findings of EG toxicity such as high anion gap acidosis (HAGMA), acute kidney injury (AKI), hypocalcemia, calcium oxalate stones, and suggestive histories of EG ingestion...
February 2024: Curēus
https://read.qxmd.com/read/38520518/n-acetylcysteine-regulates-oxalate-induced-injury-of-renal-tubular-epithelial-cells-through-cdkn2b-tgf-%C3%AE-smad-axis
#15
JOURNAL ARTICLE
Wei Cao, Jingbo Zhang, Shiliang Yu, Xiuguo Gan, Ruihua An
This study was aimed to investigate the preventive effects of N-acetyl-L-cysteine (NAC) against renal tubular cell injury induced by oxalate and stone formation and further explore the related mechanism. Transcriptome sequencing combined with bioinformatics analysis were performed to identify differentially expressed gene (DEG) and related pathways. HK-2 cells were pretreated with or without antioxidant NAC/with or silencing DEG before exposed to sodium oxalate. Then, the cell viability, oxidative biomarkers of superoxidase dismutase (SOD) and malondialdehyde (MDA), apoptosis and cell cycle were measured through CCK8, ELISA and flow cytometry assay, respectively...
March 23, 2024: Urolithiasis
https://read.qxmd.com/read/38520506/getting-hot-in-here-comparison-of-holmium-vs-thulium-laser-in-an-anatomic-hydrogel-kidney-model
#16
JOURNAL ARTICLE
Christopher Wanderling, Aaron Saxton, Dennis Phan, Karen M Doersch, Lauren Shepard, Nathan Schuler, Stephen Hassig, Scott Quarrier, Thomas Osinski, Ahmed Ghazi
As laser technology has advanced, high-power lasers have become increasingly common. The Holmium: yttrium-aluminum-garnet (Ho:YAG) laser has long been accepted as the standard for laser lithotripsy. The thulium fiber laser (TFL) has recently been established as a viable option. The aim of this study is to evaluate thermal dose and temperature for the Ho:YAG laser to the TFL at four different laser settings while varying energy, frequency, operator duty cycle (ODC). Utilizing high-fidelity, 3D-printed hydrogel models of a pelvicalyceal collecting system (PCS) with a synthetic BegoStone implanted in the renal pelvis, laser lithotripsy was performed with the Ho:YAG laser or TFL...
March 23, 2024: Urolithiasis
https://read.qxmd.com/read/38520492/optimal-duration-of-medical-expulsive-therapy-for-lower-ureteral-stones-a-critical-evaluation
#17
JOURNAL ARTICLE
Erhan Erdoğan, Gamze Şimşek, Alper Aşık, Hikmet Yaşar, Cahit Şahin, Kemal Sarıca
To evaluate the optimal duration of Medical Expulsive Therapy (MET) application for distal ureteric stones on a time period based manner. 89 patients with 5-10 mm distal ureter stones received tamsulosin (0.4 mg) for MET and diclofenac sodium (75 mg) for analgesia. Patients were evaluated once a week for 4 weeks. Radiologic stone passage was evaluated by kidney ureter bladder (KUB) and ultasonography where non-contrast computed tomography (NCCT) was also performed if needed. While 23 cases (28...
March 23, 2024: Urolithiasis
https://read.qxmd.com/read/38519285/mini-endoscopic-combined-intra-renal-surgery-miniecirs-with-endoview-puncture-in-a-12-month-boy-a-safe-but-challenging-procedure
#18
JOURNAL ARTICLE
Yesica Y Quiroz, Erika Llorens, Irene Giron, Joan Palou, Juan Carlos Osorio, Anna Bujons
INTRODUCTION: Associating minipercutaneous nephrolithotomy and retrograde flexible ureteroscopy (fURS) is called Mini Endoscopic Combined Intra-Renal Surgery (miniECIRS). It's a safe and efficient technique, also in children. MATERIAL AND METHODS: The video describes miniECIRS in a 12 month-old boy with an infectious pelvic left stone (16 mm) and multiple caliceal stones. The UAS used was a 10FR and the percutaneous access was a 14Fr with Clear-Petra® sheath...
March 6, 2024: Journal of Pediatric Urology
https://read.qxmd.com/read/38518154/percutaneous-nephrolithotomy-versus-open-surgery-in-the-treatment-of-urinary-calculi
#19
JOURNAL ARTICLE
Ruipeng Tang, Zhengjin Yi, Yong Wang, Li Wan, Xiangyu Liu, Shubin Wang, Chuan Xiao
OBJECTIVE: To evaluate the effectiveness of percutaneous nephrolithotomy (PCNL) compared with open surgery for urinary stone removal. METHODS: A total of 95 patients with urinary stones were screened for eligibility between October 2020 and December 2021. After excluding 5 patients who revoked their consent, 90 patients were randomized to receive either traditional open surgery (traditional group) or PCNL (PCNL group), with 45 patients in each group. In addition, the two groups received Shugan Qingre Tonglin decoction twice daily for 2 weeks...
March 22, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38517489/patients-undergoing-double-j-substitution-with-a-pigtail-suture-stent-report-a-significant-decrease-of-stent-related-symptoms-results-from-a-prospective-multicenter-longitudinal-trial
#20
JOURNAL ARTICLE
Andrea Bosio, Stefania Ferretti, Eugenio Alessandria, Federico Vitiello, Eugenia Vercelli, Davide Campobasso, Luca Micai, Claudia Gozzo, Glauco Bertello, Giulio Gaetano Guarino, Claudia Alice, Alessandro Bisconti, Fabrizio Fop, Paolo Gontero
PURPOSE: To compare stent-related symptoms (SRS) in patients with double J (DJ) undergoing substitution with a pigtail suture stent (PSS) after ureteroscopy (URS), through the Ureteral Stent Symptom Questionnaire (USSQ). MATERIALS AND METHODS: Patients with DJ undergoing URS for stone treatment were enrolled in this prospective multicenter longitudinal study. The USSQ was submitted thrice: 2 weeks after DJ, 2 weeks after PSS and 4 weeks after PSS removal (baseline)...
March 22, 2024: World Journal of Urology
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