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https://www.readbyqxmd.com/read/29161313/biomarkers-and-echocardiography-for-evaluating-the-improvement-of-the-ventricular-diastolic-function-after-surgical-relief-of-hydronephrosis
#1
Huei-Ming Yeh, Ting-Tse Lin, Chih-Fan Yeh, Ho-Shiang Huang, Sheng-Nan Chang, Jou-Wei Lin, Chia-Ti Tsai, Ling-Ping Lai, Yi-You Huang, Chun-Lin Chu
The pathophysiology of cardio-renal syndrome (CRS) is complex. Hydronephrosis caused by urolithiasis may cause cytokine release and lead to cardiac dysfunction. The aim of this study was to evaluate cardiac function changes observed in patients who received double J placement using feasible biomarkers and echocardiography. This was a prospective, single-center study. Eighty-seven patients who presented with acute unilateral hydronephrosis and received ureteroscope stone manipulation were enrolled. Echocardiography and cytokines were measured on the day of the operation and 24 hours after the procedure...
2017: PloS One
https://www.readbyqxmd.com/read/29160413/long-non-coding-rna-chchd4p4-promotes-epithelial-mesenchymal-transition-and-inhibits-cell-proliferation-in-calcium-oxalate-induced-kidney-damage
#2
C Zhang, J Yuan, H Hu, W Chen, M Liu, J Zhang, S Sun, Z Guo
Kidney stone disease is a major cause of chronic renal insufficiency. The role of long non-coding RNAs (lncRNAs) in calcium oxalate-induced kidney damage is unclear. Therefore, we aimed to explore the roles of lncRNAs in glyoxylate-exposed and healthy mouse kidneys using microarray technology and bioinformatics analyses. A total 376 mouse lncRNAs were differentially expressed between the two groups. Using BLAST, 15 lncRNA homologs, including AU015836 and CHCHD4P4, were identified in mice and humans. The AU015836 expression in mice exposed to glyoxylate and the CHCHD4P4 expression in human proximal tubular epithelial (HK-2) cells exposed to calcium oxalate monohydrate were analyzed, and both lncRNAs were found to be upregulated in response to calcium oxalate...
November 13, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29160109/editorial-comment-on-end-2017-0618-or-r1
#3
Mordechai Duvdevani
Percutaneous nephrolithotomy (PCNL) is currently the treatment of choice for large and complex renal calculi. One of the main advantages of PCNL is gaining a real stone-free status in a single session. However, there are several major complications that necessitate careful patient selection for this surgery (1). In this well written manuscript the authors deal with the true rates and importance of residual fragments following PCNL surgeries done in a high volume center. They reviewed 658 PCNL procedures from 2008-2013 that underwent a CT scan on post-operative day one...
November 21, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29159789/heart-failure-and-kidney-disease
#4
Dario Grande, Margherita Ilaria Gioia, Paola Terlizzese, Massimo Iacoviello
Kidney disease is commonly found in heart failure (HF) patients. They share many risk factors and common pathophysiological pathways which often lead to mutual dysfunction. Both haemodynamic and non-haemodynamic mechanisms are involved in the development of renal impairment in heart failure patients. Moreover, the presence of a chronic kidney disease is a significant independent predictor of worse outcome in chronic as well as in acute decompensated HF. As a consequence, an accurate evaluation of renal function plays a key role in the management of HF patients...
November 21, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29156745/predictive-value-of-preoperative-inflammatory-response-biomarkers-for-metabolic-syndrome-and-post-pcnl-systemic-inflammatory-response-syndrome-in-patients-with-nephrolithiasis
#5
Kun Tang, Haoran Liu, Kehua Jiang, Tao Ye, Libin Yan, Peijun Liu, Ding Xia, Zhiqiang Chen, Hua Xu, Zhangqun Ye
Neutrophil to lymphocyte ratio (NLR), derived neutrophil to lymphocyte ratio (dNLR), platelet to lymphocyte ratio (PLR) and lymphocyte to monocyte ratio (LMR) were promising biomarkers used to predict diagnosis and prognosis in various inflammatory responses diseases and cancers. However, there have been no reports regarding these biomarkers in kidney stone patients. This study aimed to evaluate the predictive value of inflammatory biomarkers for metabolic syndrome (MetS) and post-PCNL SIRS in nephrolithiasis patients...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29151118/semi-rigid-ureteroscopy-indications-tips-and-tricks
#6
REVIEW
Lily A Whitehurst, Bhaskar K Somani
Advances in ureteroscopic technology, alongside broadening treatment options have fuelled the rapid expansion of endourology. Semi-rigid ureteroscopy is a well-known procedure used globally for varying urological conditions, with high success rates. This article aims to provide 'tips and tricks' for the semi-rigid ureteroscopy procedure, and the management of commonly encountered pathology such as renal stones, ureteric strictures, and urothelial tumours.
November 18, 2017: Urolithiasis
https://www.readbyqxmd.com/read/29145637/investigation-and-management-of-renal-stone-disease
#7
Holly R Mabillard, Charles R V Tomson
No abstract text is available yet for this article.
November 13, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29142413/antiurolithiatic-potential-of-neeri-against-calcium-oxalate-stones-by-crystallization-inhibition-free-radicals-scavenging-and-nrk-52e-cell-protection-from-oxalate-injury
#8
Parveen Kumar Goyal, Santosh Kumar Verma, Anil Kumar Sharma
Background: Neeri is a well-established polyherbal formulation prescribed for renal stones by the physicians but has not been experimentally evaluated for its antiurolithiatic potential using cell-lines. Objective: This study is aimed to scientifically substantiate the antiurolithiatic effect of Neeri extract (NRE) through calcium oxalate (CaOx) crystallization inhibition, scavenging of free radicals, and protection of renal tubular epithelial NRK-52E cells from oxalate-induced injury...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29137830/efficacy-and-safety-of-tamsulosin-in-medical-expulsive-therapy-for-distal-ureteral-stones-with-renal-colic-a-multicenter-randomized-double-blind-placebo-controlled-trial
#9
Zhangqun Ye, Guohua Zeng, Huan Yang, Kun Tang, Xiaochun Zhang, Hong Li, Weibing Li, Zhong Wu, Lingwu Chen, Xingfa Chen, Xiankui Liu, Yaoliang Deng, Tiejun Pan, Jinchun Xing, Shusheng Wang, Yue Cheng, Xiaojian Gu, Wenxi Gao, Jianggen Yang, Yonghai Zhang, Qiwu Mi, Lin Qi, Jiongming Li, Weilie Hu, Peiyu Liang, Zhaolin Sun, Changbao Xu, Yongfu Long, Yongbin Liao, Siping Liu, Guoqing Liu, Xun Xu, Wei He, Zhiqiang Chen, Hua Xu
BACKGROUND: Recent large high-quality trials have questioned the clinical effectiveness of medical expulsive therapy using tamsulosin for ureteral stones. OBJECTIVE: To evaluate the efficacy and safety of tamsulosin for distal ureteral stones compared with placebo. DESIGN, SETTING, AND PARTICIPANTS: We conducted a double-blind, placebo-controlled study of 3296 patients with distal ureteral stones, across 30 centers, to evaluate the efficacy and safety of tamsulosin...
November 11, 2017: European Urology
https://www.readbyqxmd.com/read/29135147/-biomarkers-of-renal-injury-in-contact-ureteral-lithotripsy
#10
A I Tarasenko, A M Pushkarev, I G Rakipov, A V Alekseev, Ya V Kondratenko, V N Pavlov
AIM: To optimize the transurethral endoscopic management of patients with ureterolithiasis by measuring biomarkers of renal parenchymal damage. MATERIALS AND METHODS: One hundred fifty-one patients with solitary ureteral stones were tested for levels of cystatin C, neutrophil gelatinase-associated lipocalin, 2-microglobulin and interleukin 18. RESULTS: An increase in the levels of markers of renal injury was observed both in the preoperative period and after CULT...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29134277/should-mini-percutaneous-nephrolithotomy-minipnl-miniperc-be-the-ideal-tract-for-medium-sized-renal-calculi-15-30%C3%A2-mm
#11
Rajesh A Kukreja
INTRODUCTION: Reducing the percutaneous nephrolithotomy (PCNL) tract size reduces the morbidity associated with the procedure. Prolonged procedure time is a concern. Modification in technique required is to fragment the stone into smaller particles and remove them using the vacuum cleaner effect. This prospective study compares the efficacy and morbidity of reducing the tract size from the standard 24-16.5 Fr for stones sized from 16 to 30 mm. METHODS: 123 patients were enrolled in this prospective study and distributed into 2 groups based on the tract size used (group A 16...
November 13, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29130789/the-evaluation-of-radiologic-methods-for-access-guidance-in-percutaneous-nephrolithotomy-a-systematic-review-of-the-literature
#12
Alberto Breda, Angelo Territo, Cesare Scoffone, Christian Seitz, Thomas Knoll, Thomas Herrmann, Mariannhe Brehmer, Palle J S Osther, Evangelos Liatsikos
INTRODUCTION: Percutaneous nephrolithotomy (PNL) is the treatment of choice for larger and complex renal calculi. First step in performing PNL is to obtain access to the renal cavity using either fluoroscopy or ultrasound (US) guidance or a combination of both. Which guiding method to choose is controversial? A systematic review of the literature was performed comparing image guidance modalities for obtaining access in PNL. Evidence acquisition and synthesis: A PubMed, Scopus and Cochrane search for peer-reviewed studies was performed using the keywords "ultrasound" AND "fluoroscopy" AND "Percutaneous nephrolithotomy"...
November 12, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/29130401/combined-single-tract-of-minimally-percutaneous-nephrolithotomy-and-flexible-ureteroscopy-for-staghorn-calculi-in-oblique-supine-lithotomy-position
#13
Songbai Leng, Donghua Xie, Yi Zhong, Ming Huang
PURPOSE: To present our experience of combined single-percutaneous tract minimally invasive percutaneous nephrolithotomy (MPCNL) and flexible ureteroscopic lithotripsy (FURL) in managing staghorn calculi (SC) in oblique supine lithotomy position and to define the safety, efficiency, and feasibility of this approach. PATIENTS AND METHODS: Eighty-seven patients with SC treated with surgery in our hospital from March 2014 to January 2016 were retrospectively analyzed...
November 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/29118539/laparoscopic-heminephrectomy-in-horseshoe-kidneys-a-single-center-experience
#14
Santosh Agrawal, Jaisukh Kalathia, Saurabh Sudhir Chipde, Udit Mishra, Anurag Tyagi, Sanjay Parashar
Introduction: Laparoscopic approach in horseshoe kidney (HSK) is a challenge because of the aberrant vessels, the renal isthmus and the renal ectopia are all unique features of this anomaly encountered during the surgery. We report our single center experience with this technique in managing three patients with HSK. Methods: A total of 15 cases (9 males and 6 females) were operated between June 2011 and December 2016 for various indications. Of these four patients were managed laparoscopically, two patients with HSK had non-functioning renal moiety underwent transperitoneal heminephrectomy...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29117629/medical-and-dietary-interventions-for-preventing-recurrent-urinary-stones-in-children
#15
REVIEW
Adam Kern, Gwen Grimsby, Helen Mayo, Linda A Baker
BACKGROUND: Nephrolithiasis, or urinary stone disease, in children causes significant morbidity, and is increasing in prevalence in the North American population. Therefore, medical and dietary interventions (MDI) for recurrent urinary stones in children are poised to gain increasing importance in the clinical armamentarium. OBJECTIVES: To assess the effects of medical and dietary interventions (MDI) for the prevention of idiopathic urinary stones in children aged from one to 18 years...
November 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29107030/cessation-of-ureteral-colic-does-not-necessarily-mean-that-a-ureteral-stone-has-been-expelled
#16
Natalia Hernandez, Sarah Mozafarpour, Yan Song, Brian H Eisner
PURPOSE: To evaluate whether cessation of renal colic is consistent with an expelled ureteral stone or whether imaging may be indicated even in the absence of symptoms. MATERIALS AND METHODS: A retrospective study was performed of patients who presented to our institution with acute renal colic and ureteral stone and subsequently were evaluated at a follow-up visit where they reported complete cessation of pain for at least 72 hours. RESULTS: Fifty-two (52) patients met inclusion criteria and reported no pain for at least 72 hours at the time of follow up visit...
October 26, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29105635/clinical-efficacy-of-unani-medicine-renax-for-treatment-of-urolithiasis
#17
Mushtaq Ahmad, Ghazala Shaheen, Saeed Ahmad, Muhammad Akram, Syed Muhammad Ali Shah, Shahbaz Ahmad Zakki
Stone formation occurs most commonly in acute and chronic renal failure. A kidney stone is a solid lump made up of crystals that separate from the urine and build up on the inner surfaces of the kidney. The current study was conducted to investigate the clinical efficacy of Unani medicine Renax in comparison with allopathic medicine (Spironolactone + Furosemide) to treat urolithiasis. The study was conducted in District Dera Ghazi Khan, South Punjab region. This was case control, randomized, double blind clinical study...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29104789/evaluation-of-selected-doppler-parameters-of-renal-blood-flow-in-patients-undergoing-extracorporeal-shock-wave-lithotripsy
#18
Krzysztof Balawender, Stanisław Orkisz
Introduction: Despite the risk of complications, which does not exceed several percent, extracorporeal shock wave lithotripsy (ESWL) causes morphological and functional changes in kidneys as a result of the effect of the generated shock wave energy on the renal parenchyma structure. Material and methods: Forty-two patients were included in the study. The mean age in the studied group was 50.9 years (SD ±13.7). Extracorporeal lithotripsy treatments were carried out during the period from January 2014 to April 2014 using an electromagnetic shock wave generator...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/29102376/-evaluation-of-stone-size-before-flexible-ureteroscopy-which-measurement-is-best
#19
R Diamand, M Idrissi-Kaitouni, E Coppens, T Roumeguère, F Legrand
PURPOSE: To retrospectively assess the clinical utility in ureteroscopy (URS) planning of radiological parameters as predictor of stone-free status after a single flexible ureteroscopy. MATERIAL: Sixty-seven patients with renal stones treated by flexible URS were retrospectively evaluated. To assess the clinical utility of radiological parameters, relationships between stone-free (SF) status and stone burden (maximal diameter, calculated area, calculated volume, cumulative diameter, and tridimentionnal volume [V3D]) were analyzed using the area under the receiver operating characteristics curve and logistic regression...
November 1, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29102372/renal-potassium-physiology-integration-of-the-renal-response-to-dietary-potassium-depletion
#20
REVIEW
Kamel S Kamel, Martin Schreiber, Mitchell L Halperin
We summarize the current understanding of the physiology of the renal handling of potassium (K(+)), and present an integrative view of the renal response to K(+) depletion caused by dietary K(+) restriction. This renal response involves contributions from different nephron segments, and aims to diminish the rate of excretion of K(+) as a result of: decreasing the rate of electrogenic (and increasing the rate of electroneutral) reabsorption of sodium in the aldosterone-sensitive distal nephron (ASDN), decreasing the abundance of renal outer medullary K(+) channels in the luminal membrane of principal cells in the ASDN, decreasing the flow rate in the ASDN, and increasing the reabsorption of K(+) in the cortical and medullary collecting ducts...
November 1, 2017: Kidney International
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